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2014 Award Recipients and Recognition

Honorary Membership

| Honorary Members |

Award Recipients

| Achievement | Arnold J. Lehman |
| Best Postdoctoral Publication Awards | Board of Publications |
| Colgate-Palmolive Grants for Alternative Research |
| Congressional Science Leadership Award | Distinguished Toxicology Scholar | Education |
| Founders | Global Senior Scholar Exchange Program |
| Leading Edge in Basic Science Award | Merit | Public Communications |
| SOT/AstraZeneca/SOT Endowment Fund/IUTOX Travel Awards |
| Translational Impact Award | Undergraduate Educator Award |

Student/Postdoc Award Recipients

| Colgate-Palmolive Awards for Student Research Training in Alternative Methods |
| Colgate-Palmolive Postdoctoral Fellowship Award in In Vitro Toxicology |
| Perry J. Gehring Diversity Student Travel Award |
| Pfizer SOT Undergraduate Student Travel Awards |
| Syngenta Fellowship Award in Human Health Applications of New Technologies |

Recognition

| SOT Endowment Award Recipients |

 

Honorary Membership

 
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Honorary Membership

John B. Gurdon, Kt, DPhil, DSc, FRS

John B. Gurdon, Kt, DPhil, DSc, FRS, was a zoology undergraduate at Oxford University and returned, after a postdoc year at CalTech, as Lecturer in Embryology. In 1971, he joined the MRC molecular biology lab in Cambridge to continue his work on amphibian developmental biology. In 1983 as John Humphrey Plummer Professor of Cell Biology at the University of Cambridge, he co-founded a research institute of developmental and cancer biology (now named the Gurdon Institute) with Professor Laskey, acting as Chairman until 2002. His career has concentrated on nuclear transplantation in the frog and experiments to discover the value of mRNA microinjection, mechanisms of response to morphogen gradients, and recently, mechanisms of nuclear reprogramming by Xenopus oocytes and eggs. Master of Magdalene College Cambridge from 1995–2002, he has received various recognitions, including the 2009 Lasker Award for Basic Medical Science and the Nobel Prize for Physiology or Medicine in 2012.

The Society is pleased to recognize Dr. Gurdon as a 2014 SOT Honorary member.

Honorary Membership

Donald E. Ingber, MD, PhD

Donald E. Ingber, MD, PhD, is the Founding Director of the Wyss Institute for Biologically Inspired Engineering, Harvard University; the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children’s Hospital; and Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences. He also leads the Biomimetic Microsystems platform in which microfabrication techniques from the computer industry are used to build functional circuits with living cells as components. Dr. Ingber has authored more than 325 publications and 70 patents and has received numerous honors including the Holst Medal, Pritzker Award from the Biomedical Engineering Society, Rous-Whipple Award from the American Society for Investigative Pathology, Lifetime Achievement Award from the Society of In Vitro Biology, the Department of Defense Breast Cancer Innovator Award and SOT Leading Edge in Basic Science Award.

The Society is pleased to recognize Dr. Ingber as a 2014 SOT Honorary member.

SOT Award Recipients

 

Achievement

Matthew J. Campen, PhD, MSPH

Matthew J. Campen, PhD, MSPH, is awarded the 2014 SOT Achievement Award.

Dr. Campen received his PhD degree from the Department of Environmental Science and Engineering at the University of North Carolina at Chapel Hill, School of Public Health in 2000 and is an Associate Professor, Pharmaceutical Sciences Department, College of Pharmacy, University of New Mexico, in Albuquerque, New Mexico, since 2009.

Dr. Campen has established methods to assess mode of action of vascular dysfunction and mediator-based injury. He has developed an innovative approach in vitro where he can use rodent blood vessels as a biometric tool to detect and assess mediators that arise in the serum humans exposed to ozone or PM. His laboratory is unique in its ability to explore acute vascular injury and the pathogenesis of atherosclerotic disease due to chronic air pollution exposure.

Dr. Campen has contributed a great deal to our understanding of how airborne toxicants, such as particulate matter and ozone, cause systemic vascular insult. His most recent work (Channell et al., Tox Sci 2012; Robertson et al., 2013) has shown that, in both rodents and humans, exposure to inhaled pollutants can induce compositional changes in the blood that leads to inflammatory responses in the systemic vasculature, which is effectively the initiating step in atherosclerosis. Additionally, Dr. Campen has contributed to regulatory efforts by the Environmental Protection Agency, writing sections on cardiovascular health outcomes related to carbon monoxide and particulate matter for recent Integrated Science Assessments.

Dr. Campen has been a member of SOT since 2002. He received the Mary O. Amdur Award for Environmental Inhalation Toxicology in 1999 and the Young Investigator Award, from the Inhalation and Respiratory Specialty Section in 2013. He served in the presidential chain for the Mountain West Regional Chapter of SOT from 2005–2007. He was a member of the SOT Disease Prevention Task Force, 2008–2011. In addition, Dr. Campen was President and a Founding Officer of the Cardiovascular Specialty Section, 2010–2012. He currently serves on the Publications Committee (2012–2016, Co-Chair, 2013). Dr. Campen served with distinction as the interim Co-Editor-in-Chief of Toxicological Sciences during this past year.

The Society is pleased to present the Dr. Campen with the 2014 SOT Achievement Award.

 


Arnold J. Lehman

B. Bhaskar Gollapudi, PhD

B. Bhaskar Gollapudi, PhD is awarded the 2014 SOT Arnold J. Lehman Award.

Dr. Gollapudi received his PhD degree in Biology from the Dalhousie University, Canada. He is currently a Senior Managing Scientist in Exponent’s Health Sciences Center for Toxicology and Mechanistic Biology.

Dr. Gollapudi specializes in genetic toxicology and chemical carcinogenesis with emphasis on the identification of mode of action and human relevance. Dr. Gollapudi has made many contributions to the field of Genetic Toxicology including the development of novel approaches for assessing genotoxicity, integration of contemporary molecular biology techniques to understand the mode of genotoxic action, and more importantly in leading the push for a paradigm shift in the dogma that there are no thresholds for genotoxic chemicals.

Currently, he is leading an effort under the auspices of International Workshops on Genotoxicity Testing (IWGT) to standardize a new in vivo gene mutation assay (Pig-a) which can be easily integrated into any repeat dose toxicity studies. Dr. Gollapudi has contributed to the area of transgenic animal models for mutagenicity and carcinogenicity assessment and spearheaded their validation in the chemical/agrochemical industry to inform risk assessment. His focus has been on the application of genetically engineered animal models for the identification of mode of action and human relevance of toxicology findings. In recent years, Dr. Gollapudi contributed to the emerging field of epigenetics by critically evaluating its role in product safety assessment and investigating potential markers predictive of adverse toxicological outcomes. He has applied latest technologies in the safety assessment of a diverse portfolio of substances.

Dr. Gollapudi has been a member of the Society of Toxicology since 1998. He has been very active within the Society having served as Associate Editor of Toxicological Sciences from 2005–Present; member, the SOT Scientific Program Committee from 2011–Present; and member of SOT Career Resource and Development (CRAD) Committee from 2007–2010.

The Society is pleased to present Dr. Gollapudi with the 2014 Arnold J. Lehman Award.

 

Annie Lumen, PhD
National Center for Toxicological Research/US FDA, Jefferson, AK

Lumen A, Mattie DR, Fisher JW.

Evaluation of Perturbations in Serum Thyroid Hormones during Human Pregnancy Due to Dietary Iodide and Perchlorate Exposure Using a Biologically Based Dose-Response Model
Toxicological Sciences, 2013 Mar;133(2):320–341.).


Gul Mehnaz Mustafa, PhD
University of Texas Medical Branch, Galveston, TX

Mustafa GM, Petersen JR, Ju H, Cicalese L, Snyder N, Haidacher SJ, Denner L, Elferink C.

Biomarker Discovery for Early Detection of Hepatocellular Carcinoma (HCC) in Hepatitis C (HCV) Infected Patients
Molecular and Cellular Proteomics, 2013 Sep 5. [Epub ahead of print].


Phoebe A. Stapleton, PhD
West Virginia University, Morgantown, WV

Stapleton PA, Minarchick VC, Yi J, Engels K, McBride CR, Nurkiewicz TR.

Maternal Engineered Nanomaterial Exposure and Fetal Microvascular Function: Does the Barker Hypothesis Apply?
American Journal of Obstetrics and Gynecology, 2013 Sep; 209(3): 227.e1–227.e11.

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Board of Publications

The Society of Toxicology Board of Publications Paper of the Year has selected the paper entitled “The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma” as the best paper published in Toxicological Sciences in the past year. The authors are Anja Schinwald, Fiona A. Murphy, Adriele Prina-Mello, Craig A. Poland, Fiona Byrne, Dania Movia, James R. Glass, Janet C. Dickerson, David A. Schultz, Chris E. Jeffree, William MacNee, and Ken Donaldson. The research was conducted at MRC/ University of Edinburgh. Nano-Engineering Answers to Asbestos Toxicity

Many are familiar with the commercials recruiting people into class action lawsuits for mesothelioma. The scruples of the late-night Saul Goodmans notwithstanding, mesothelioma is a real health concern. Inhalation of asbestos fibers can lead to chronic lung inflammation with devastating results. The malignancies that develop in the parietal pleura impair pulmonary function, cause significant chest pain, and lead to other abdominal difficulties. Thousands of people are diagnosed every year. Many of the sufferers were exposed in the workplace decades ago.

For years we have known that inhalation of the fibers was dangerous. The precautionary steps taken during asbestos abatement are with good reason, but we know less about the process of mesothelioma initiation. What is the role of the fiber dimensions in the disease? Specifically, the field has wanted to ascertain the length at which the fibers become pathogenic. Asbestos products used in industrial nations are a mixed bag with a wide array of fiber lengths. It has been nearly impossible to figure out this threshold length.

In Toxicological Sciences (Toxicological Sciences 2012, 128(2): 461–470), research from the laboratory of Ken Donaldson took advantage of high aspect ratio nanomaterials (HARN), nanowires, nanotubes, and nanorods, to shed some light on this problem. The explosive growth of nanotechnology has put an ominous cloud over HARN. There is concern that such materials may lead to future health concerns analogous to the asbestos-mesothelioma connection, but the Donaldson group went right to the silver lining…literally. By synthesizing silver nanowires of precise lengths and then testing them for their ability to cause pleural inflammation, they were able to identify the toxic threshold 4 microns. Additional experiments with carbon nanotubes and nickel fibers confirmed the results; fibers longer than 4 microns induced inflammation, a key event in mesothelioma initiation.

While the direct introduction of the materials into the pleural cavity bypasses the normal route of inhalation, we know that long (>25 micron) asbestos fibers traverse these barriers and end up in this pleural space. It is likely that many of the HARN will possess the same qualities as asbestos. Fortunately, we know the dangers of fiber particles and with HARN we have the ability to control their synthesis.

This study not only provided much needed insight into the initiating events in asbestos-induced mesothelioma, it could also prompt changes in industry practices that can prevent future disease incidence. By identifying the threshold length for inflammation, they have generated a blueprint for safer products. As they suggest in the paper, the engineering process of synthetic nanofibers should follow the green chemistry slogan of “benign-by-design.” Ideally, industries involved in the production of HARN will read the findings published here in ToxSci, embrace the benign mantra, and work to design and produce products with reduced toxic potential. The field of toxicology will always be open for business, but wouldn’t it be nice if things slowed down a bit?

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Distinguished Lifetime Toxicology Scholar

Senator Tom Udall (D-NM)

Senator Tom Udall (D-NM), is the recipient of the 2014 SOT Congressional Science Leadership Award. He began serving as United States senator in 2009, after two decades of public service as a US representative and New Mexico’s state attorney general. Throughout his career, Senator Udall has been a strong advocate for the hardworking families of New Mexico, for a clean energy economy and the environment, for affordable and accessible health care, and for our nation’s veterans. He has also been a leader in the fight for campaign finance reform and for making government more accountable to the American people, not the special interests. He serves on five committees as New Mexico’s senior senator: Appropriations, Foreign Relations, Environment and Public Works (EPW), Indian Affairs, and Rules and Administration.

The senator is receiving the Congressional Science Leadership Award because of his unflagging support for science, preventive health care, and a healthy environment. He is particularly commended for his leadership role in TSCA reform legislation, as well as on renewable energy and many other pro-environment stances. Senator Udall is champion of scientific integrity and integrating science into policymaking.
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Distinguished Lifetime Toxicology Scholar

Richard E. Peterson, PhD

Richard E. Peterson, PhD, is awarded the 2014 Distinguished Toxicology Scholar Award.

Dr. Peterson currently serves as the Charles Melbourne Johnson, Distinguished Chair in Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison. He received his PhD in Pharmacology, in 1972, from Marquette University School of Medicine, Milwaukee, Wisconsin.

Dr. Peterson has made a number of seminal contributions in the areas of reproductive and developmental toxicology, ecotoxicology, cardiovascular toxicology, and risk assessment. He helped to develop and apply TEQ approaches to real world scenarios resulting in a tremendous positive societal benefit. He determined, for the first time, that lake trout embryos in Lake Ontario were exquisitely sensitive to dioxin and dioxin-like compounds. He predicted that if the environmental contaminant levels declined, the population would thrive. The breeding recovery in Lake Ontario lake trout that has taken place is consistent with the decrease in dioxin and dioxin-like compounds. He observed that the cardiovascular system was the primary target of these compounds in fish embryos. This led his group to establish zebrafish as a model for developmental toxicity. Recent efforts have demonstrated that dioxin impacts the development of the cardiovascular and craniofacial system by altering the expression of well-conserved genes opening up opportunities for rapid translational studies. His work has led to a paradigm shift to allow the use of aquatic models for human health related research and has laid a path for scientists to follow. His research on dioxin in fish, birds and mammals demonstrated that embryo and/or fetal exposure is far more susceptible to dioxin toxicity than adult exposure. These findings enhanced recognition of the risk that embryonic exposure to dioxin poses to fish and wildlife populations and to children’s health and revealed how little is known about environmental factors, like dioxin, in the fetal basis of adult disease.

The Society is pleased to present Dr. Peterson with the 2014 SOT Distinguished Toxicology Scholar Award.

 

Education

Herman N. Autrup, PhD, ATS

Herman N. Autrup, PhD, ATS, is the 2014 SOT Education Award recipient.

Dr. Autrup received his PhD in Experimental Pathology in 1975 from the University of Nairobi, Kenya. He currently serves as a professor in Environmental Medicine, Institute of Public Health, at University of Arhus in Denmark.

Dr. Autrup has made impressive contributions to education in the area of environmental health. He established the curriculum in environmental and occupational medicine at Aarhus University in 1990 and currently teaches courses in Human Toxicology, a course in Toxicology and Environmental Health as part of a diploma program offered by Aarhus University, and lectures in environmental and occupational medicine for medical students. These courses are widely recognized in Scandanavia and are well attended each year. Professor Autrup also is editor for the textbook “Miljø- og Arbejdsmedicin” (Environmental and Occupational Medicine) that is used throughout Denmark.

Even more impressive than his teaching efforts within Denmark, Professor Autrup has made a concerted effort to bring education in environmental health to other areas of the world—often where it is most needed. In 1998, he developed a graduate-level course in Environmental and Health Risk Assessment and Management of Toxic Chemicals for the Chulabhorn Research Institute in Bangkok, Thailand. More recently, he also has developed an Advanced Environmental Health Sciences for the doctoral training program at the Chulabhorn Research Institute. Finally, Professor Autrup has extended his global outreach and has been invited to give lectures and present executive-level short courses on risk assessment and toxicology by professional organizations in Uganda, Zimbabwe, Kenya, Bolivia, Thailand, Vietnam and Bhutan.

Dr. Autrup serves as an Associate Editor of Toxicological Sciences and has been a member of SOT since 1998.

The Society is pleased to present Dr. Autrup with the 2014 Education Award.

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Founders Award

John A. Thomas, PhD, ATS



John A. Thomas, PhD, ATS, is the 2014 SOT Founders Award recipient.

Dr. Thomas received his PhD from the University of Iowa in 1961. Currently he a Professor Emeritus in the Department of Pharmacology at the University of Texas Health Science Center—San Antonio, in Texas; as well as an Adjunct Professor at the Indiana University School of Medicine, Indiana.

Throughout his distinguished career, Dr. Thomas’s contributions to toxicological sciences in many different areas ranging from the safety of nutrients and food ingredients, to pharmaceuticals, diagnostics, health promoting agents and environmental chemicals have been highly recognized by his peers and the scientific community. He continues to be an educator and a scientist, and the discipline of toxicology will continue to benefit from his vision and leadership. During his years in academia, he mentored undergraduate and graduate students, post doctoral fellows and numerous colleagues.

In addition to his several decades as an educator in the United States and internationally, Dr. Thomas has volunteered his expertise as a member of various governmental science boards and advisory committees, on various editorial boards, and has provided his expertise as a consultant to the US FDA, National Academy of Sciences and the Department of Defense. Dr. Thomas is a Past-President of the Academy of Toxicological Sciences and also the American College of Toxicology. He is a Fellow in the American College of Toxicology and also the Russian Academy of Medical Sciences.

As a member of SOT since 1971, Dr. Thomas has served as an SOT Continuing Education Lecturer (1983, 1985, and 1988); SOT Councilor (1985–1987); President of two Regional Chapter Executive Committees: Midwest Chapter (1988) and Gulf Coast Chapter (now Lone Star Chapter—1998); and as the SOT Education Committee Chair (2000). He is the recipient of multiple prestigious awards including the SOT Merit Award (1998) and both the Commissioner’s and Distinguished Service Awards from the US FDA.

The Society is pleased to further recognize Dr. Thomas with the 2014 Founders Award.

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Global Senior Exchange Program

Gonzalo J. Diaz, DVM, PhD



Gonzalo J. Diaz, DVM, PhD, is widely recognized in the field of mycotoxins and plant toxins especially in the Andean region. He is a Professor of Toxicology in the Department of Sciences for Animal Health, College of Veterinary Medicine, at the National University of Colombia. He received his MS and PhD degrees at the University of Guelph, Ontario, Canada, with Colombian sponsorship. His PhD in Toxicology/Nutrition was in the Department of Animal and Poultry Science, Ontario Agricultural College and he continued there with postdoctoral research in the Proteomics Laboratory, Department of Biomedical Sciences. He holds two patents, has authored four books and numerous book chapters and other publications.

The National University of Colombia is the largest academic institution in Colombia, having close to 30,000 students and eight campuses across the country. The Toxicology Program is under the Department of Toxicology in the College of Medicine, consisting of faculty from different departments and colleges. Currently he serves as the head of the Toxicology Laboratory and director of the Avian Nutrition and Toxicology Research Group. He supervises graduate students in both the Human Toxicology and Veterinary Toxicology programs as well as teaches an undergraduate course on Veterinary Toxicology and two graduate courses on Advanced Toxicology and Toxicants of Natural Origin.

The Global Senior Scholar Exchange Program will assist Dr. Diaz in establishing collaboration in the field of mycotoxins as well as strengthening the existing toxicology graduate program. Dr. Diaz is interested in toxins produced during the processing of foods such as acrylamides. This is of particular interest in Colombia as deep fried carbohydrate-containing foods are normally consumed and may contain these toxins. Some foods such as yucca (Manihot sculenta), plantain, potato, and corn chips are of particular interest in Dr. Diaz’s research. Specific areas of collaboration between Dr. Diaz and his host institution will focus on toxicants of natural origin and from food processing. Toxins from plants and from fungi can affect both animals and humans and are strictly regulated in human foods. Investigating fungi requires the existence of laboratories that are highly competent in mycotoxin testing and staffed with experienced toxicologists in this field.

Global Senior Scholar Exchange Program

Wilson Kiiza Rumbeiha, DVM, PhD, DABT, ABVTD

Dr. Diaz will be hosted by Wilson K. Rumbeiha under the Interdepartmental Graduate Toxicology Program at Iowa State University (ISU). Dr. Rumbeiha was the Section Head of the Veterinary Diagnostic Toxicology Laboratory, College of Veterinary Medicine, at Michigan State for over 12 years before relocating to ISU where he now conducts research on neurotoxicology of sulfide gases, cyanotoxins, and applied clinical and diagnostic veterinary toxicology. He also is the president of Toxicologists Without Borders, a humanitarian organization of toxicologists working with other professions to solve toxicology-related issues in developing countries. ISU is an institution with a vibrant interdepartmental toxicology program with an intense curriculum leading to the award of MS and PhD degrees. The Veterinary Toxicology Training Program is one of two active Veterinary Toxicology Residency Training programs in the US The broader interdepartmental program has core members from departments across campus including Food Safety and Nutrition. Some of the core faculty are engaged in mycotoxin research. Dr. Diaz will have the opportunity to interact with faculty of the Interdepartmental Toxicology Program. Dr. Diaz’s program will benefit from learning how the host curriculum is structured to strengthen the existing toxicology graduate program at the National University of Columbia. In addition, Dr. Rumbeiha will travel to Colombia to engage in teaching, curriculum development, and to explore collaborative research projects.

 

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Global Senior Scholar Exchange Program

Ebenezer O. Farombi, PhD, FRSC



Ebenezer O. Farombi, PhD, FRSC, is currently Dean, Faculty of Basic Medical Sciences, and Director, Molecular Drug Metabolism and Toxicology Research Laboratories, at the University of Ibadán. He received his PhD from the University of Ibadan and completed his postdoctoral training at the University of Liverpool, UK.

Dr. Farombi’s research over the past 20 years has included molecular toxicology, cellular oxidative stress mechanisms in toxicology, reproductive and environmental toxicology, antioxidant redox biochemistry, nutraceuticals as prophylactic agents, and nutrigenomics. He is known nationally and internationally for his contributions on the biochemical and molecular mechanisms of chemoprevention using Kolaviron, a natural antioxidant biflavonoid from the seed of Garcinia kola (bitter kola, a widely consumed nut in West Africa). The Department of Biochemistry and its Toxicology program are recognized for their pioneering research on environmental compounds such as aflatoxins, palmotoxins, N-nitroso compounds, perfluidone and aryl alkyl sulfonamide pesticides, glyphosates (a broad spectrum herbicide), naturally occurring coumarin compounds chalepin, imperatorin and oxypeucadanine isolated from medicinal plants, and polycyclic aromatic hydrocarbons.

An effective and productive researcher and supervisor, he has mentored over 150 graduate students in areas including environmental and reproductive toxicology and chemoprevention. He has authored or co-authored over 130 scientific articles and ten book chapters and recently edited the book Nutritional Antioxidants in Cancer and Degenerative Diseases with contributors from Nigeria, Cameroon, USA, Mauritius, South Africa, Japan, and Denmark. Dr. Farombi has received several international fellowships and grants. He is currently Vice-President of the Society for Free Radical Research (SFRR)-Africa, and serves as Editor-in-Chief of the journal of the West Africa Society of Toxicology (WASOT).

Global Senior Scholar Exchange Program

James E. Klaunig,
PhD, ATS, IATP

James Klaunig will host Dr. Farombi in the Toxicology Program at Indiana University (IU). Dr Klaunig is Professor of Environmental Health in the IU School of Public Health at Bloomington. His research for the past 38 years has been devoted to understanding the mechanism of action of toxic agents and the risk of these agents to humans with emphasis in the field of chemically induced cancer and pathology (Klauniglab.com). The Toxicology Program at IU Bloomington is a multidisciplinary program in the Department of Environmental Health with significant collaborations of faculty across the Bloomington campus, including the School of Public and Environmental Affairs. The IU Toxicology Program has a long history of international interactions both at the student and visiting scientist levels as well as through international research collaborations. A major new strategic initiative of Indiana University is further development of international interactions, particularly in Africa.

Some of the expectations for this Global Senior Scholar Exchange include updating graduate training in molecular and biochemical toxicology at the University of Ibadan, developing a mechanism for interchange of graduate and postdoctoral trainees, strengthening collaboration and facilitating technology transfer, and increasing exposure to toxicogenomics and molecular techniques relevant to probing the underlying toxicity mechanisms of environmental chemicals. Ultimately Dr. Farombi would like to increase the capacity of the toxicology program in Ibadan University and the region to produce well-trained toxicologists to address safety, quality, and regulatory standards for drugs, chemicals, and foods. For example, the use of complementary and alternative medicines derived from medicinal plants prepared by traditional doctors is very common in the region and there is a dearth of appropriately trained scientists to investigate the safety profiles of these medicines. This and similar programs are invaluable in helping the region make a dent in the vast need for local expertise.

 

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Leading Edge in Basic Science Award

Vishal S. Vaidya, PhD

Vishal S. Vaidya, PhD, is the 2014 Leading Edge in Basic Science Award recipient.

Dr. Vaidya received his PhD in Toxicology from the University of Louisiana in 2003. As an Assistant Professor at Harvard Medical School, he leads the Systems Toxicology Program within Harvard Program in Therapeutic Sciences and directs the Laboratory of Kidney Toxicology and Regeneration at Brigham and Women’s Hospital.

His work in the past five years will change the way textbooks are written and science is conducted with respect to deploying biomarkers for monitoring kidney damage. Dr. Vaidya challenged the fundamental mechanism of kidney toxicity regarding injury assessment and developed, evaluated, and validated novel tools for biomarker detection applicable from bench to bedside, comparing the remarkably consistent sensitivity and specificity of urinary Kim-1 over several other potential biomarkers in a large number of collaborative studies. These studies are going to have a very significant impact on the way we monitor for kidney toxicity in drug development and in the clinic.

The outcome of his work in collaboration with Predictive Safety Testing Consortium is such that Kim-1 is now accepted by US, European, and Japanese Regulatory Agencies as a suitable marker of kidney injury to be used in drug discovery. Currently he is exploring the role of fibrinogen and related molecules and miRNA’s as possible mechanistic markers of kidney injury in humans.

In 2011, Dr. Vaidya was awarded the Outstanding New Environmental Scientist Award by NIEHS and in 2013, he was chosen to be one of six North American scientists to receive the Innovation in Regulatory Science Award from Burroughs Wellcome Fund. Dr. Vaidya has been a member of the Society since 1999. During this time he has served as a member of the CRAD Committee (2006–2009) and Continuing Education Committee (2011–2014). He has also served as Councilor to the SOT Northeast Regional Chapter.

The Society is pleased to present Dr. Vaidya with the 2014 Leading Edge in Basic Science Award.

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Merit

Jay I. Goodman, PhD

Jay I. Goodman, PhD, is awarded the 2014 SOT Merit Award.

Dr. Goodman is Professor, Department of Pharmacology and Toxicology, and Faculty Member, Center for Environmental Toxicology, Michigan State University. He is a Diplomate of the American Board of Toxicology and a Fellow of the Academy of Toxicological Sciences. His research interests are focused on discerning epigenetic mechanisms underlying carcinogenesis and other chemical-induced toxicities, and testing the hypothesis that the capacity to maintain the normal epigenetic status is related inversely to susceptibility to carcinogenesis.

Extensively involved in the training of the next generation of toxicologists, scientists and physicians, Dr. Goodman has served as a mentor and advisor for many PhD students and postdoctoral fellows. He chaired his Department’s Graduate Committee from 1979–1997 and served as the Interim Chair of the Department of Pharmacology and Toxicology, Michigan State University from 2001–2002.

Dr. Goodman has received numerous awards for his scientific achievements, including the Distinguished Alumnus Award, Doctoral Program in Pharmacology, The University of Michigan; the John Barnes Prize Lecture, British Toxicology Society; and the George H. Scott Memorial Award from the Toxicology Forum, among others. He is also the first American to serve on a EUROTOX committee.

Dr. Goodman has participated actively on numerous SOT Committees and Task Forces including the Awards, Nominating, and Program Committees, and in SOT leadership as President of the Michigan Regional Chapter, SOT Secretary, and SOT President. He has published more than 125 peer reviewed manuscripts, given numerous invited presentations both nationally and internationally, and has participated on review panels and advisory boards for the NIH, NIEHS, NSF, NTP, US EPA, CDC, American Board of Toxicology, Academy of Toxicological Sciences, and the International Life Sciences Institute, Health and Environmental Sciences Institute. He continues to serve on editorial boards and as an advisor on toxicologic issues.

The Society is pleased to present Dr. Goodman with the 2014 Merit Award.

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Public Communications Award

David L. Eaton, PhD

David L. Eaton, PhD, is awarded the SOT Public Communications Award.

Dr. Eaton is Professor of Environmental and Occupational Health Sciences and Dean and Vice Provost of the Graduate School at the University of Washington, in Seattle, Washington. He also has served as the Director of the NIEHS P30 Center for Ecogenetics & Environmental Health at the UW since 1995, and currently Chairs the Research Committee of the Health Effects Institute.

Dr. Eaton has and continues to communicate understanding of toxicology to a broad community of nontoxicologists. He has served as an ambassador of Toxicology in many circles and helped to promote the standing of toxicology and environmental health sciences through the world. In addition to his many scientific contributions, Dr. Eaton was one of the pioneers in recognizing the importance of disseminating the message of toxicology to the public and launched one of the first community outreach and education programs in environmental health in the nation.

Dr. Eaton has authored 115 peer reviewed publications 40 book chapters, including the ‘Principles of Toxicology’ chapters in Casarett and Doull’s Toxicology, Rosenstock and Cullen’s Textbook of Occupational and Environmental Medicine, and Sipes, McQueen et al.’s Comprehensive Toxicology series. Relevant to this award, he has an additional 17 general education articles that target audiences outside of Toxicology. He reached out to the legal community providing presentations to law students and has publications directly targeted to lawyers. Some Attorneys and Judges tout Dr. Eaton’s article “Scientific judgment and toxic torts: A primer in toxicology for judges and lawyers” as the definitive source on adjudicating expert testimony and determining whether acceptable scientific practices have been followed in tort cases. He has served on numerous National Academy of Sciences/National Research Council committees, helping to communicate scientific advice to federal agencies and organizations, often related to controversial areas in toxicology.

Dr. Eaton has been very active in the leadership of the Society of Toxicology. Appropriately he first began as a member on the Committee on Public Communications From there he served on various committees including Membership and Finance Committees. He also served as a member on the Board of Publications in addition to many other advisory boards, task forces and working groups. He received the SOT Achievement Award in 1993. He has the distinction of having served on the Society’s Council as SOT Secretary and SOT President. Dr. Eaton was elected, as a fellow of the Academy of Toxicological Sciences in 2000, and as a fellow of the American Association for the Advancement of Science in 2003. He was recently elected to the Washington Academy of Sciences and in 2011 was elected to the Institute of Medicine of the National Academies. The Society is pleased to present Dr. Eaton with the 2014 Public Communications Award.

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Samir Abbès, PhD, Higher Institute of Biotechnology of Béja, Béja, Tunisia

Wafa Hassen, PhD, High Institute of Biotechnology, University of Monastir, Monastir, Tunisia

Gopabandhu Jena, PhD, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India

Sameeh A. Mansour, PhD, National Research Centre, Giza, Egypt

Siti N. Mubarokah, MSc, Laboratory of Pharmacology, School of Medicine, University of Islam Malang, Malang, Indonesia

Olufunke E. Ola-Davies, PhD, University of Ibadan, Ibadan, Nigeria

Iyekhoetin M. Omoruyi, MSc, Benson Idahosa University, Benin City, Nigeria

Ishiaq Omotosho, PhD, College of Medicine, University of Ibadan, Ibadan, Nigeria

Muneeb U. Rehman, PhD, Department of Pharmaceutical Sciences, University of Kashmir, Sprinagar, India

Yang Song, PhD, Zhejiang Academy of Medical Sciences, Hangzhou, China

Jing Zhang, MSc, Shanxi Medical University, Taiyuan City, China

 



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Translational/Bridging Travel Award

Timothy D. Phillips, PhD, ATS

Timothy D. Phillips, PhD, ATS is awarded the 2014 SOT Translational Impact Award

Dr. Phillips is a Distinguished Professor and holds the Reed Endowed Chair in Toxicology at Texas A&M University. Since joining the faculty in 1979, he has published more than 185 papers.

Dr. Phillips’ pioneering research in the US and Africa has established that dioctahedral smectite clays, used as Ancient Medicine more than 2,000 years ago, can bind and render harmless food-born contaminants such as aflatoxin B1. These toxins have been strongly associated with disease and death in people, particularly infants and children in developing countries. The findings from his research are directly relevant to high risk populations (animals and humans) who suffer the consequences as a result of frequent dietary aflatoxin exposure. This work is expected to improve food and feed safety, quality, and security for greater than 4.5 billion people and their animals living in climates conducive to the growth of fungi.

Dr. Phillips’ ongoing translational work in the US and Africa has confirmed the safety, palatability and efficacy of field-practical, clay-based strategies. The delivery of a therapeutic dose of clay has been established using common foods and nutritional supplements. Further developments of his research have resulted in wide-ranging implications for the prevention of chemotherapy-induced diarrhea and the treatment of chronic gastrointestinal illness.

Additionally, Dr. Phillips teaches future toxicologists on the subjects of Food Toxicology, Scientific Ethics and Chemical Hazard Assessment. He is an internationally recognized leader in Food Safety and Toxicology, and has served on panels for numerous International Organizations and Academic Institutions worldwide.

Dr. Phillips has been a member of SOT for over 30 years. During this time he has served on multiple SOT Awards and Nominating Committees. He was also the President of the Lone Star Regional Chapter (formerly known as the Gulf Coast Chapter).

The Society is pleased to present Dr. Phillips with the 2014 SOT Translational Impact Award.

 

UndergradEducator

William D. Atchison, PhD



William D. Atchison, PhD, is awarded the 2014 SOT Undergraduate Educator Award.

Dr. Atchison received his PhD in Pharmacology from the University of Wisconsin, School of Pharmacy. Currently he serves as Associate Dean for Research and Graduate Studies, College of Veterinary Medicine, Michigan State University. There he received the MSU Distinguished Faculty Award, which is among the highest honors bestowed upon faculty members. Dr. Atchison’s research has resulted in over 95 articles in peer-reviewed literature and 14 book chapters. During his tenure, he has trained 17 PhD students, 6 graduate students and more than 100 undergraduate students.

Dr. Atchison’s passion is to provide opportunities for undergraduate education in the biomedical sciences coupled with research experiences aimed at under-represented minority students. In collaboration with the University of Puerto Rico, he developed and established an NIH, NINDS-funded R25-Diversity Education grant that provides research experiences for Hispanic undergraduates, since 2005. Dr. Atchison makes annual visits to campuses of the University of Puerto Rico to recruit/interview students for the program. Many of these students have gone on to participate in SOT’s Annual Meeting by presenting their research. To date, 40 undergraduate students have received training through this program. Similarly, Dr. Atchison has received funding from Michigan State University’s College of Veterinary Medicine to initiate a smaller program for preveterinary students.

Dr. Atchison has been very active member of SOT. He has served on the SOT Program Committee and as Secretary/Treasurer and then President of the Neurotoxicology Specialty Section. He is a recipient of the SOT Astra Zeneca Travelling Lectureship and at the SOT Annual Meeting, Dr. Atchison contributes yearly to the Undergraduate Education Program that serves under-represented minority students.

The Society is proud to present Dr. Atchison with the 2014 SOT Undergraduate Educator Award.

Sponsored Award Recipients

 
 

Patricia E. Ganey, PhD
Michigan State University,
East Lansing, MI

Project Title: Prediction of Idiosyncratic, Drug-induced Liver Injury from Drug-Cytokine Interaction In Vitro

 

Matthew Troese, PhD
MB Research Laboratories,
Spinnerstown, PA

Project Title: In Vitro Coculture Assay for Identification of Dermal Sensitizers

 

 

Jonathan H. Shannahan, PhD
University of Colorado,
Aurora, CO

Project Title: In Vitro Assessment of Vascular Nanoparticle-Induced Toxicity: Implications for a Susceptible Human Subpopulation

 

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Dilshan S. Harischandra, BS
Iowa State University, Ames, IA

Project Title: Role of the Environmental Neurotoxicant Manganse in Cell-To-Cell Transmission on α-synuclein in Parkinson’s Disease


 

Student Award Recipients

 

Laura E. Armstrong, BS
University of Rhode Island, Kingston, RI

Project Title: Isolation and Culture of Mature Adipocytes to Study Induction of the Antioxidant Response in Dieting and Obesity

Host Institution: Institution Boston Nutrition Obesity Research Center—Adipose Biology and Nutrient Metabolism Core (ABM), Boston University—Department of Medicine, Boston, MA

 

Christin M. Grabinski, MS
US Air Force Research Laboratory, Dayton, OH

Project Title: Design and Validation of Nanomaterial Aerosol Exposure Techniques for In Vitro Toxicology.

Host Institution: University of Pennsylvania, Philadelphia, PA

 

 

 

Pamella B. Tijerina
New York University School of Medicine, Tuxedo Park, NY

 

 




Wesley Cai,
University of Arizona,
Tucson, AZ

 

Cory V. Gerlach,
Oregon State University,
Corvallis, OR

 

Lukas Gora,
Michigan State University, East Lansing, MI

 

Elaine Kuo,
Stanford University,
Stanford, CA

 

Virginia Mitchell,
University of Utah,
Salt Lake City, UT

 

Kia Z. Perez-Vale,
University of Puerto Rico,
Arecibo, PR

 

Ricardo Rivera-Soto,
University of Puerto Rico,
Arecibo, PR

 

Bradley Rowland,
McMurray University,
Abilene, TX

 

Kelly Schlotman,
Purdue University,
West Lafayette, IN

 

Jennette Shoots,
Kenyon College,
Gambier, OH

 

Kelly VanDenBerg,
Michigan State University,
East Lansing, MI

 

 




 



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