Types of Algorithms (cont)

• Sequence comparisons

  • Simple cross-sequence comparisons  10 20 30 40musacc CCCCGGGCTGTATTCCCCTCCATCGTGGGCCGCTCTAGG X::::::: :: ::::::::::::::::: ::: : :::humacc CCCCGGGCCGTCTTCCCCTCCATCGTGGGGCGCCCCAGG 170 180 190 200 
  • Comparisons based on substitution matrices using matrix file BLOSUM50 70 80 90 100MWRTC1 EIESKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA :::... ::.::.:....:: :...:.:.::..:.... : MWKW EIEKRIQEKEEEFENTRKNHARALESMQASLETEAKGKAEL 1590 1600 1610 1620 

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