Scientific Sessions

Program Overview

Symposium Sessions

• Autism: Genetic, Epigenetic, and Environmental Factors Influencing Neural Networks
• Autophagy In Toxicology: Essential Process, Adaptive Process, and Disease Process
• Does the Clock Make the Poison? Influence of the Circadian Clock on Toxicological Mechanisms and Outcomes
• Emerging Issues at the Intersection of Reproductive and Mixtures Toxicology
• Macrophages—Regulators of Toxicity and Disease Pathogenesis
• Mechanisms of Inflammation in Skin Carcinogenesis
• New Insights into the Nrf2-Keap1 Pathway and Its Impact on Human Disease
• Ribotoxic Stress: Mechanisms and Models for Human Disease
• Stem Cell Biology and Cell Therapy Approaches to Understanding Cellular Injury and Wound Healing in Dermal, Ocular, and Pulmonary Injury
• Toxicological Considerations in the Gulf of Mexico Oil Spill
• Uncovering the Role of Non-Coding RNAs in Toxicology
• Vascular Developmental Toxicity: Identification, Prioritization, and Application
• Vascular Injury: A Figment of Your Inflammation?

Symposium Sessions: Thematic Track

Emerging Global Public Health Issues Thematic Track

• Translational Toxicology: Molecules to Global Health

Environment and Disease Thematic Track

• Developmental Exposure to Environmental Toxicants: From Persistent Toxicities to Diseases
• Developmental Origins of Adult Disease: The Effects of Low-Dose Lead
• Epigenetics, Metals, and Cancer
• Gene-Environment-Disease Interactions in Fish Models of Human Disease
• Human Variability in Susceptibility to Environmental Toxicants

Global Air Quality and Human Health Thematic Track

• Environmental Oxidative Pollutants-Induced Pulmonary Toxicity
• Metabolic Basis of Respiratory Tract Chemical Toxicity

Integration of Toxicological and Epidemiological Evidence to Understand Human Risk Thematic Track

• When is Exposure Not Exposure? Defining the Dose-Response Region Between “Effect” and “Adverse Effect”: Implications for Human Health Risk Assessment

Novel Approaches to Preclinical Safety Assessment: Bridging the Gap between Discovery and the Clinic through Translational Toxicology Thematic Track

• High Content Imaging-Applications in Toxicology and Toxicity Testing
• Human Pluripotent Stem Cells and Neural Progenitors as Models Of Gene-Environment Interactions In Neurological Disease

Toxicity Testing: State of Science and Strategies to Improve Public Health Thematic Track

• The Use of Epidemiological Data and PBPK Modeling in a Risk Assessment for Manganese That Considers Its Essentiality

Workshop Sessions

• Are We There Yet? Attrition in the Pharmaceutical Industry and Impactful Strategies for Reducing Failure
• Autoimmunity Versus Systemic Hypersensitivity: Commonalities Useful for Immunotoxicity Testing
• De-Risking the Potential for Cardiovascular Toxicity of Type 2 Diabetic Drugs: Preclinical and Clinical Strategies
• Extending Pulmonary Toxicity Findings for Nanomaterials
• Identification of Chemical Respiratory Allergens: Principles and New Developments
• Meeting the Challenges of Respiratory Toxicology Testing: In Search of Best Practices
• Nonclinical to Clinical Abuse Liability Assessment of Drugs: Current Practices, Challenges, and Impact of Recent Regulatory Guidance
• Polishing Today’s Job Candidate in a Tough Economy
• Protein Aggregation as a Common Mechanism of Toxicity in Neurodegenerative Diseases
• Technical Characterization and Dosimetry Challenges Associated with Conducting or Interpreting Nanotoxicity
• The Spectrum of Systems Biology
• Understanding Structural and Physical Chemical Drivers of Drug Toxicity: Utility and Translatable Value
• Understanding the Implications of Preclinical Seizures for Clinical Drug Development

Workshop Sessions: Thematic Track

Emerging Global Public Health Issues Thematic Track

• Advancing Predictive Ecotoxicology Testing and Environmental Risk Assessment in the 21st Century
• Disease Prevention: The Next 50 Years
• Risk Assessment for Proteins Introduced into Genetically Modified Crops
• Role of Biomarkers in Assessing Tobacco Harm Reduction: A Toxicological Perspective
• Safer Products for a Sustainable World: Linking Chemical Design and Toxicology

Integration of Toxicological and Epidemiological Evidence to Understand Human Risk Thematic Track

• Approaches for Incorporating Non-chemical Stressors into Cumulative Risk Assessments
• New Approaches for Integrating Toxicological and Epidemiological Data to Better Inform Risk Assessment
• PBPK Model Use in Risk Assessment: Why Being Published Is Not Enough
• Using Mode of Action Data to Guide Quantitative Cancer Risk Assessment: A Case Study of Hexavalent Chromium in Drinking Water

Roundtable Sessions

• Assessment of Nanoparticle Exposure in Occupational Settings and in Inhalation Toxicology Studies: Is there a Best Dosemetric to Use?
• Current Uses and Understanding of the Tissue Cross Reactivity Assay
• ‘Omics in Toxic Tort
• Reforming the Toxic Substances Control Act (TSCA): Challenges, Opportunities, and Timing

Roundtable Sessions: Thematic Track

Emerging Global Public Health Issues Thematic Track

• Risk and Risk Management of Potentially Toxic Compounds Formed by Cooking Food

Toxicity Testing: State of Science and Strategies to Improve Public Health Thematic Track

• Integrating Alternative Test Methods into the Federal Regulatory Framework

Historical Highlights Sessions

• 1961 to 2011 and Beyond: The Evolution of Toxicology
• 50 Years of “the Pill”: Risk Reduction and Discovery of Benefits Beyond Contraception

Informational Sessions

• Current and Changing Perspectives on Mycotoxins and their Potential Health Risks Worldwide
• Toxicological Considerations of Pharmacotherapy During Pregnancy

Informational Sessions: Thematic Track

Global Air Quality and Human Health Thematic Track

• Coordinating Global Chemical Safety: The Big Four

Integration of Toxicological and Epidemiological Evidence to Understand Human Risk Thematic Track

• Beyond Science and Decisions: From Problem Formulation to Dose-Response
• Emerging Science for Environmental Health Decisions: Tools, Strategies, and Evidence

Novel Approaches to Preclinical Saftety Assessment: Bridging the Gap between Discovery and the Clinic through Translational Toxicology Thematic Track

• Livers on a Plate: Next Generation Hepatocyte Models for High-Throughput Screening and Mode of Action Prediction
• Precision Cut Tissue Slices Revisited: A Classical Method Meets New Challenges

Toxicity Testing: State of Science and Strategies to Improve Public Health Thematic Track

• Progress of the Tox21 Consortium in High Throughput Bioactivity Profiling of Chemicals
• The Application of the Threshold of Toxicological Concern Concept to the Preclinical Safety Assessment of Non-Pharmaceutical Medical Products, Including Medical Devices and Combination Drug-Device Products
• The International Cooperation on Alternative Test Methods (ICATM): Translating Science to Provide Improved Public Health Safety Assessment Tools

Education-Career Development Sessions

• From Pilot Grants to High-End Journals: The Science of Writing
• Social Media and Informatics Essentials for Toxicologists

Toxicity Testing: State of Science and Strategies to Improve Public Health Thematic Track

• Bringing Toxicology to the Decision-Makers Table: Opportunities for Science Policy Positions in Washington D.C.

Regional Interest Session

• Bombs in Our Backyards? Historical Military Activities and Current Public Health Issues in the U.S. Captial Region