Animal Hematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers By G. O. Evans, Wellcome Research Laboratories, UK (retired)
When looking for books in this field, you may find multidisciplinary books with chapters on toxicology, major textbooks written primarily for human medicine, or books geared toward the veterinary field, but few that focus on animal hematoxicology written specifically for laboratory scientists. Until now. Animal Hematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers explores the intersection of these fields and also those areas where the "rules" for human hematology and toxicology do not always apply.
Features:
Presents information on main laboratory animal species with tables of reference values
Includes a chapter on bone marow evaluation containing material on micronucleus tests in genetic toxicology
Explores pre-analytical effects and the common laboratory measurements that indicate fundamental differences in cell counting techniques
Discusses difference between blood cell numbers, shapes, and sizes for laboratory animals
Provides key references on published reference ranges for laboratory animals
The Toxicology and Biochemisty of Insecticides By Smon J. Yu, University of Florida, Gainesville USA
Considers the biological, physiological, and environmental consequences of pesticide use.
The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research in insect detoxification. It discusses mechanisms at the molecular level such as specific enzymes that contribute to insecticide susceptibility and influence hose plant selections in phytophagous insects.
Beginning with a general introduction, eleven chapters integrate classical toxicology with physiology, biochemisty, and molecular biology to present a comprehensive look at the field. The book discusses the demand and formulation of pesticides and describes each type from dusts and powders to baits and aerosols. It classifies insecticidesby target, chemical compound, and mechanism; evaluates toxicity testing procedures; explains pesticide uptake, mode of action, and metabolism; and explores species differences, resistance, and interactions. It also considers pesticides in the environment and federal and state regulatory legislation and enforcement.
A long-waited, state-of-the-science review on insect toxicology, this indispensable book brings you up-to-date on the many aspects and implications of pesticide use and provides the necessary background and platfom from which to conduct future research.
Principles of Food Toxicology By Tõnu Püssa, Estonian University of Life Sciences, Tartu Estonia
Skillfully combining theory and applications, this text introduces toxicology principles at the molecular, cellular, and organism level. The author uses vivid examples, as well as highly detailed, yet accessible information, to emphasize the biochemical mechanisms of toxic effects and toxic response. The book also provides a systemic characterization of the most important food borne toxicants.
Combines general principles of toxicology with the characterization of food-borne toxicants
Explains the biochemistry and chemistry required for thorough understanding of toxicological principles
Provides explanations of the mechanisms of toxic effect and medicinal consequences
Features a comprehensive catalog of all of the most important food-borne toxicants
Environmental Toxicants: Human Exposures and Their Health Effects By Morton Lippmann, New York University Medical Center, USA
Gain the most current information and research available for performing risk assessments on exposed individuals and populations. Giving guidance to public health authorities, primary care physicians, and industrial managers, this third edition:
Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment
Updates and revises the previous editio, in light of current scientific literature and its significance to public health concerns
Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles.
Molecular and Biochemical Toxicology (Fourth Edition) By Robert C. Smart; Ernest Hodgson, North Carolina State University, USA; Editors
Clear and comprehensive, this book covers a range of dynamic aspects in biochemical and molecular toxicology. Compiled and authored by a diverse group of experts, it guides students and professional toxicologists through a broad rand of issues and helps solve problems of basic toxcology questions, integrating myriad fields from nutrition to genetics to toxicology. This latest edition adds timely and thorough coverage of molecular toxicology, including proteomics, toxicogenomics, metaolomics, pharmaco (toxico) genetics.
Fundamentals of Analytical Toxicology By Robert J. Flanagan, King's College Hospital NHS Foundation Trust, UK; Andrew A. Taylor, Royal Surrey County Hospital, UK; Ian D. Watson, Aintree Hospitals, UK; Robin Whelpton, Queen Mary, University of London, UK
This book aims to give principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. The book covers aspecs of sample collection, transport, storage and disposal, and sample preparation as well as general aspects of method implementation/validation and laboratory operation. It concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results.
544 pages | Hardcover or Paperback | 2008
ISBN: 978-0-470-31934-5 or 31935-2
USD: $180.00 or $80.00; CAD: $197.99 or $87.99
On-line Book: ISBN: 978-0-470-51629-4
Toxicology and Risk Assessment: A Comprehensive Introduction By Helmut Greim, Technical University of Munich; Robert Snyder, The State University of New Jersey, USA; Editors
Describing the basic concepts of toxicology, Toxicology and Risk Assessment equips you with the skills required to evaluate risks at given exposures. Topics covered include:
Principles in Toxicology: toxicokinetics including absorption, distribution, metabolism, and excertion; the mechanisms that lead to cytotoxicity, carcinogenicity and effects on reproduction, and the toxic effects on mixtures of chemicals
Organ Toxicology: information on anatomy and physiology of the major organs; why they are specific targets; and the mechanisms of specific chemicals affecting these organs
Methods in Toxicology: the commonly used methods used for toxicity testing, both in vivo and in vitro.
Hepatotoxicity: From Genomics to In Vitro and In Vivo Models By Saura Sahu, Editor
Hepatotoxicity is an authoritative compilation of the most recent advances in this important discipline, presented by international experts and demonstrating the multidisciplinary nature of this science. With this work, you'll gain essential insight into current trends in this area of research and the future directions it may take. A partial sampling of topics covered includes biomarkers of hepatotoxicity, genomics of hepatotoxicity, gender difference in hepatotoxicity, hepatotoxicity of botanical supplements, and risk assessments of hepatotoxins.
The Dose Makes the Poison: A Plain-Language Guide to Toxicology By M. Alice Ottoboni
Improve your understanding to toxic chemicals without taking the time to go back to school. Thoughtful discussions of controversial issues help you to understand news media reports on toxicology, avoid the half-truths that lead to "poison paranoia," and make informed judgments about our use and control of chemicals. The Dose Makes the Poison, Second Edition, is an easy-to-read review of toxicology that has become "required reading" for scientists and managers throughout industry, public health officials, environmental scientists, industrial hygienists, and hazardous waste workers.
Patty's Industrial Hygiene and Toxicology By Eula Bingham, Barbara Cohrssen, Charles H. Powell
Hailed by industry experts as the most reliable, comprehensive, and state-of-the-art reference on the principles and practice of industrial hygiene and occupational health and safety, Patty's Industrial Hygiene and Toxicology is now more accessible that ever before. Containing all 13 volumes of the print edition, this CD-ROM offers quick access to current information on industrial hygiene, occupational safety, toxicological properties of chemical agents, research trends, regulations, permissible exposure level data, and much more. Patty's CD-ROM includes full texts, charts, tables, and illustrations from the celebrated reference, and features:
Simple and complex Boolean searching capabilities
Hyperlinked references, tables, and figures
Comprehensive electronic index for the entire database.
Toxicogenomics: A Powerful Tool for Toxicity Assessment By Saura Sahu, US Food and Drug Administration
Toxicogenomics delivers up-to-date state-of-the-art information presented by recognized experts, and so serves as an authoritative source of curent knowledge in this field of research. The potential link between toxicology, genetics, and human diseases makes this book very useful to investigators in many and varied disciplines of science and toxicology. A sampling of the many topics covered include mechanistic toxicogenomics, the analysis and interpretation of toxicogenomics as a tool to assess immunotoxicity, and the application of toxicogenomics in drug discovery.
Nanoscience and Nanotechnology: Environmental and Healh Impacts By Vicki H. Grassian, Editor
Covering various aspects of nanoscience and nanotechnology and what is know about the potential environmental and health impacts, this comprehensive book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechnology.
Brings together, uniquely in on source, research on environmental implications of nanotechnology and engineered nanoparticles
Has broad interdisciplinary appeal for chemist, engineers, environmental scientists, material scientists, toxicologists, occupational and environmental health specialists, and regulatory personnel
Handbook of Toxicogenomics: A Strategic View of Current Research and Applications By Jürgen Borlak, Fraunhofer Institute of Toxicology and Experimental Medicine, Germany; Editor
Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical perspective. Here, expets from all the fields mentioned will find solid information provided by an international team of experienced authors. With its approach as an interdisciplinary overview, it will prove particularly useful for all those needing to develop appropriate research strategies.
Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals By Sean Ekins, Editor
This unique volume explains how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools. You'll discover how QSAR methods are applied to enzymes, transporters, nuclear receptors, and ion channels. The book also clearly shows how in vitro models are used, covers newer technologies, and addresses regulatory aspects. It offices a complete systems perspective regarding risk assessment prediction and discusses experimental and computational approaches in detail. There are also sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena.
Toxicogenomics: Principles and Applications By Hisham K. Hamadeh, Cynthia A. Afshari, both of Amen, Inc. USA; Editors
Providing a unified, thorough text on key breakthrough technololgies in genomincs, proteomics, metabonomics, and bioinformatics, as well as their applications to toxicology research, this book includes:
A general introduction to toxicology for nonspecialists
The ILSI Health and Environmental Sciences Institute (HESI)
The ILSI Health and Environmental Sciences Institute (HESI) requests proposals on emerging issues for 2009. Deadline for submission: Tuesday, September 2, 2008. Please visit the Web site for more information.
Just published!
Toxicology Principles for the Industrial Hygienist Edited by William E. Luttrell, Warren W. Jederberg, and Kenneth R. Still
AIHA's Toxicology Principles for he Industrial Hygienist, the most comprehensive toxicology reference, is written by industry experts specifically for the industrial hygienist. Emphasis is on basic principles and case studies that relate to the working environment. This book is recommended for classroom text as well as a professional resource.
The book's 36 chapters provide thorough discussions of
Understanding Toxicology
Sites of Action of Chemicals Found in the Workplace
To order visit www.aiha.org/market or call AIHA Customer Service at (703) 849-8888, Monday–Friday, 9:00 AM–5:00 PM ET.
NLM's Disaster Information Management Research Center (DIMRC)
The National Library of Medicine has released a web resource for the
Disaster Information Management Research Center (DIMRC) http://disasterinfo.nlm.nih.gov. The DIMRC web site seeks to provide access to quality disaster health
information at all stages of preparedness, response, mitigation, and
recovery. DIMRC will focus its efforts on providing disaster health
information resources and informatics research that will be directly
beneficial for public health officials, healthcare providers, special
populations, and the public.
Carcinogenic Potency Database
CPDB, the Carcinogenic Potency Database, was developed by the
Carcinogenic Potency Project at the University of California, Berkeley,
and by the Lawrence Berkeley National Laboratory. CPDB includes 6540 chronic, long-term animal cancer tests (both positive
and negative for carcinogenicity) from the general published literature
as well as from the National Cancer Institute and the National
Toxicology Program. Such tests are used in support of cancer risk
assessments for humans. Information that is important in the
interpretation of bioassays is reported in CPDB for each experiment.
Users can search for results on each chemical in TOXNET via chemical
name or name fragment, or by Chemical Abstracts Service Registry Number
(RN). Results include a summary for each sex-species tested, including
carcinogenicity, target organs, and carcinogenic potency values.
Detailed results from each experiment on the particular chemical are
given in a plot format suitable for screen viewing. Chemical structure,
InChI, and SMILES codes are reported.
The National Library of Medicine's Dietary Supplements Labels Database http://dietarysupplements.nlm.nih.gov includes information from the
labels of over 2,000 brands of dietary supplements in the marketplace,
including vitamins, minerals, herbs or other botanicals, amino acids,
and other specialty supplements. The database is designed to help both the general public and health care
providers find information about ingredients in brand-name products,
including name, form, active and inactive ingredients, amount of active
ingredient/unit, manufacturer/distributor information, suggested dose,
label claims, warnings, percentage of daily value, and further label
information.
Provides information on chemical hazards that could impact our way of life. The book address safety data for chemicals in cleaning solvents, pharmaceuticals, plastics…etc.
The Second Edition glossary contains definitions and explanatory notes
for terms frequently used in the multidisciplinary field of toxicology.
It also contains a list of abbreviations and acronyms used in
toxicology, a list of abbreviations and acronyms used by international
bodies and by legislation relevant to toxicology and chemical safety,
and a listing of the classifications of carcinogenicity according to the
weight of evidence available.
Now Available: Enhanced ToxSeek Meta-Search Engine and
Clustering Tool An updated version of ToxSeek is now available
(toxseek.nlm.nih.gov). ToxSeek is an NLM metasearch engine and
clustering tool that enables the simultaneous searching of many
different toxicology and environmental health information databases and
web sites.
ToxSeek enhancements include:
A new spell checker with English and medical dictionaries
The automatic
inclusion of medical subject headings (MeSH) in the subject clusters
The addition of TOXMAP (environmental health e-maps) and ToxTown
(an interactive guide to commonly encountered toxic substances)
Refinements to the search strategies of the CPSC (Consumer Product
Safety Commission) and CDC (Centers for Disease Control and Prevention)
sites
The addition of WHO (World Health Organization).
Toxipedia is a free toxicology encyclopedia and resource center providing comprehensive,
accurate, and scientifically based information on the hazards and risks
of chemical and physical agents, with the goal of advancing human and
environmental health. The site includes a quality control system too.
This FAQ provides guidance on the roles of the Institutional Official
and the IACUC in developing plans to diminish the likelihood that their
institution or its employees will become targets of animal activists.
Institutions are encouraged to review OLAW FAQs and make use of this
resource.
Free Access to the New Online Archive of the Royal Society
Access, the most complete
350-year-old archive of journals for the Royal Society, includes every paper
published in the Royal Society journals since 1665. The vice president
and chair of the Publishing Board, Professor Martin Taylor, described
the uniqueness of the collection as holding interest not only for
scientists but also for anyone with an interest in history. "The rich,
varied, and sometimes entertaining archive documents the earliest
accounts of the seventeenth century's new experimental philosophy,
through which an understanding of the natural world was acquired by
experiment and observation. www.pubs.royalsoc.ac.uk.
New Brochure on PHS Policies on Humane care and Use of Laboratory Animals
OLAW has created a brochure intended to communicate to investigators
their responsibilities under PHS Grants Policy and PHS Policy on Humane
Care and Use of Laboratory Animals. What Investigators Need to Know About
the Use of Animals provides a succinct resource for investigators to
quickly grasp the main expectations and requirements when using animals
in research supported by the PHS. The brochure may be accessed at http://grants.nih.gov/grants/olaw/InvestigatorsNeed2Know.pdf.
OLAW will provide institutions with enough copies to disseminate to all
of their investigators that work with animals. Send requests, along with
the number of copies needed, to olaw@od.nih.gov, and please be sure to
provide your complete mailing address.
CiteULike—Free Service for Academics to Share, Store and
Organize papers
CiteULike is
a free service to help academics to share, store, and organise the academic
papers they are reading. When you see a paper on the web that interests
you, you can click one button and have it added to your personal library.
CiteULike automatically extracts the citation details, so there's no need
to type them in yourself. It all works from within your web browser. There's
no need to install any special software. Because your library is stored
on the server, you can access it from any computer. You can share your
library with others, and find out who is reading the same papers as you.
In turn, this can help you discover literature which is relevant to your
field but you may not have known about.
ScienceSlides—The Leading Tool for Scientific Lectures
and Seminars ScienceSlides is a lecture and seminar companion for Microsoft
Powerpoint aimed at helping scientists and teachers to create professionally
looking slides quickly. Available for both Mac OSX and Microsoft Windows,
for more information and a demonstration about ScienceSlides 2006 visit
www.visiscience.com.
Improved and Updated 2006 Version now available! Over 400 new compounds
and slides. Numerous updates in all fields, expanded diabetes, obesity
and cardiovascular sections. New feature—References in selected
Molecular Pathology and Signaling slides.
Who is ScienceSlides
made
for? Scienceslides for PowerPoint is an indispensable tool for time—conscious
scientists and educators in biomedical fields who require professional presentation
material to support their scientific presentations.
Why do I need ScienceSlides?
Why spend time searching for compound
structures when you have an exhaustive library of objects ready for use.Why
spent time on drawing DNA, signaling pathways, cell structures
and hundreds of
other objects when you can use ScienceSlides' quality objects.
Why spend time
searching reference textbooks for metabolic pathways, signaling pathways, cellular
processes, genetic diseases, etc, when you have them just few clicks
away in PowerPoint's graphical format. Ever used a JPEG signaling
pathway or object and wished you could modify it for your particular
needs? Our slides and objects are fully editable as .ppt files!
MySlidesTagger—Organize your slides and Presentations!Your
personal slide management and sharing system. MySlidesTagger will
make you more organized and save you time! Retrieving and previewing
slides that have similar names but different tags will be a snap.
Read more about MySlidesTagger and how this program can help you here
on the Visiscience Web site. Order now for only $49. Free PowerPoint
tutorials and tips for scientists!Visit our tutorials website for
free guides, tips, and tutorials on PowerPoint that may help you
create better slides. Recent entries include:
* Creating the
impression of depth and perspective with cell membranes
* Applying colors, gradients, shine
and reflections to PowerPoint objects.
* Making posters with PowerPoint
* and much more...
(c) Visiscience Corp. 2006 All rights reserved. ScienceSlides
and the ScienceSlides logo are registered trademarks of VisiScience,
Corp. All other trademarks mentioned in this document or Web site
are property of their respective owners. VisiScience reserves the
right to change the content of ScienceSlides. ScienceSlides requires
Microsoft Windows 2000, XP, or Mac OS X 10.2 and Microsoft PowerPoint
2000 or higher.
VisiScience
PO BOX 4385
Chapel Hill, NC 27515
Training
CD in basic Methodology for Laboratory Mice available from NIH
The National Human Genome Research Institute Office of Laboratory
Animal Medicine has developed a training CD in Basic Methodology
for Laboratory Mice that illustrates the most common practices used
in the NIH intramural research program. It was developed to promote
proficiency in performing common techniques in the mouse. It consists
of eight training modules, table of contents, list of definitions,
and help and reference sections. To obtain a copy of the CD, send
your name, research institution affiliation, full mailing address
and email address to rodent-cd@mail.nih.gov
. One CD per request, please. From AMP News Service Digest, Monday,
January 17, 2005.
Dermatotoxicology,
Sixth Edition, ISBN #0415288622 CAT#TF1588
Author(s) Dr. Hongo Zhai, Dr. Howard I. Maibach List Price $219.95,
Special Price $186.97
Reflects
recent advances in skin toxicology
Contains
25 new chapters covering concepts and methods
Describes
the current state of knowledge of dermatotoxicology
Covers the
mechanisms of action of toxicants on the skin
For twenty-five
years, Dermatotoxicology has stood as the definitive reference book
in the field. A generation of toxicologists and dermatologists has
consulted this volume throughout their careers, finding within it
a wealth of theoretical and practical guidance. Updated and expanded
to reflect the latest developments in skin toxicology, Dermatotoxicology,
Sixth Edition includes fundamental information on the mechanisms
of action of toxic substances on the skin, as well as practical
information on the various methods to evaluating dermal toxicity.
It is unparalleled in its coverage, and this new edition broadens
its scope to include chapters on: mdiprima@crcpress.com
Quantitative Structure Activity Relationships (QSARs)
for Pollution Prevention, Toxicity Screening, Risk Assessment and
Web Applications is the first in a series of books
that describes “current practices” related to the regulatory
acceptance of QSARs. The book provides readers with information
on QSAR topics at a fraction of the cost associated with a larger
book dealing with all aspects of QSARs. It features a chapter entitled
"QSARs for new practitioners" to provide a working knowledge
of QSARs to those who may have a passing interest in QSARs, but
have a desire to learn more. Also included is a unique chapter that
provides hundreds of references on QSARs for pollution prevention,
toxicity screening, risk assessment and web applications from journal
publications, book chapters and documents that were published in
the past 25 years. The book concludes with a “future challenges”
chapter that describes some of the challenges facing QSAR developers
and users related to the regulatory acceptance of QSARs for promoting
pollution prevention, implenting toxicity screening, conducting
risk assessments and employing web applications. Order
on-line at Amazon.com
Current Protocols in Toxicology, Contact: John
Wiley & Sons, Inc., Attn: P.Spillane-9th Floor, 605 Third Avenue, New
York, NY 10158-0012; Tel: (800) 825-7550; E-mail: protocol@wiley.com.
Journal
of Toxicology and Environmental Health, Part B: Critical Reviews.
In keeping with the original scope of Part A, Part B
focuses on environmental toxicology in general as well as on special
interest fields such as: environmental factors affecting health;
target organ toxicities; immunotoxicology; risk assessment; carcinogenesis
and mutagenesis; ecotoxicology and aquatic toxicology.
Part B serves
as an indispensable resource for toxicologists, risk assessment,
industrial hygienists, environmental and occupational physicians,
environmentalists, pharmacologists, biochemists, radiation biologists,
and epidemiologists, as well as for helth care professionals, health
and safety administrators, and oncologists.To order contact: Taylor
& Francis, Attn: Journals Customer Service, 325 Chestnut Street,
Philadelphia, PA 19106; Web site: www.tandf.co.uk;
E-mail:customerservice@taylorandfrancis.com;
Tel: (800) 354-1420 x216.
Risks
Associated with Smoking Cigarettes with Low Machine-Measured Yields
of Tar and Nicotine, The National Cancer Institute (NCI)
Tuesday released this 251-page monograph detailing the dangers of
"low tar" cigarettes. The monograph, the thirteenth in
NCI's Smoking and Tobacco Control Monograph Series, reports findings
that reductions in cancer rates are due to decreases in smoking
prevalence not to changes in cigarette design, which according to
NCI, have done little to address public health needs in the past
50 years. NCI here reports on ways in which smokers compensate for
lower levels of tar and nicotine, reasons why Federal Trade Commission
(FTC) testing methods are inadequate, and marketing methods designed
to give smokers a false sense of security regarding low tar and
nicotine cigarettes. Users can download
the monograph by chapter or as a whole in pdf format.
Book price comparison site that allows you to search for the best prices on toxicology-related books at on-line booksellers like Barnes and Noble, Amazon and many more.
SOT is dedicated to creating a safer and healthier world by advancing the science of toxicology.
