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SOT Science News Alert April 2014

Dear SOT Members,

Below are a number of SOT-sponsored meetings and events that may be of interest to you. For more information, contact the organizers directly.

Drug Safety: Bridging the Divide Between Preclinical and Clinical Drug Safety—Applications Due May 18

A Gordon Research Conference on Drug Safety: Bridging the Divide Between Preclinical and Clinical Drug Safety, will be held June 1–6 at Stonehill College, Easton, Massachusetts. The goals of this new conference are to stimulate discussion of contemporary approaches to assessing drug safety and to bridge the divide that exists between individuals working in pre-clinical and clinical drug safety research. An additional objective is to catalyze discussions among drug safety experts in academia and industry, so as to create opportunities for collaboration and to strengthen the valuable relationship between basic and applied research in the field of drug safety. The target audience is an equal mix of academic and industry scientists striving to improve drug safety. Funding is available for graduate students and postdoctoral fellows who are presenting outstanding posters. Full program details are available on the conference website as well as the application to attend this conference. Apply by May 18.

Society of Toxicologic Pathology 33rd Annual Symposium—June 22–26, 2014

“Translational Pathology: Relevance of Toxicologic Pathology to Human Health” is the theme of the Society of Toxicologic Pathology (STP) 33rd Annual Symposium, which will be held June 22–26, 2014, at the Marriott Wardman Park Hotel in Washington, DC. Topics will include the predictive value of nonclinical models and how animal models and human endpoints inform each other, progress in the development of new nonclinical animal models and other types of models, emerging technologies that have the potential to improve translational capabilities, the role and utility of epigenetic endpoints in toxicologic pathology and their relevance to human health, how pathology outcomes inform human health assessments and regulatory decisions, and the challenges of developing translational models that provide useful information on human populations with comorbidities. By the end of this symposium, the audience will have a better understanding of current trends and data needs in translational pathology and how the field can leverage expertise and tools to meet these needs. An interactive pre-meeting National Toxicology Program (NTP) Satellite Symposium will be held on Saturday, June 21, and four Continuing Education (CE) Courses will be offered on Sunday, June 22. The scientific sessions on Tuesday, June 24, have been designed in response to requests from the Federal regulatory community. US Government employees may register by June 1 to attend Tuesday sessions at no charge. Visit the 2014 STP Annual Meeting website to view the program and additional meeting details on exhibits, sessions, CE courses, and special events

Teratology Society 54th Annual Meeting—June 28–July 2, 2014

The theme of the 54th Annual Meeting of the Teratology Society is “Pushing the Boundaries of Birth Defects Research.” The meeting will highlight the latest scientific information and technology in birth defects and developmental disabilities research. Symposium topics include early prenatal diagnosis of birth defects, testicular dysgenesis syndrome, epigenetics, and thrombosis during pregnancy. The meeting also will feature special programs for the next generation of birth defects researchers including a workshop on building a career in developmental toxicology and a NEW Student Innovative Design Competition for improving prenatal development and child health. This competition asks students to imagine novel solutions to technical problems in the broad field of teratology—encompassing anything from a new measurement technique for exposure to environmental contaminants during pregnancy to a wireless method for assessing fetal health. The interdisciplinary nature of the Society provides unique opportunities to look broadly at complex issues. The Annual Meeting will be held June 28–July 2, 2014, in Bellevue, Washington, located on the eastside of Seattle. For more information, visit the Teratology Society Annual Meeting website.

Environmental Mutagenesis and Genomics Society 45th Annual Meeting—September 13–17, 2014

The 45th Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS) will be held September 13–17, 2014, at the Hilton Orlando Lake Buena Vista, in Orlando, Florida. This year’s theme is “Integrating Environmental, Genomic, and Health Research.” The meeting will provide a forum for the latest research on DNA damage and repair, mechanisms of mutagenesis, epigenetic regulation, and their contributions to environmentally-induced human disease. In addition, current regulatory issues and risk assessment strategies will be discussed. EMGS is unique in that it provides a platform for the cross-disciplinary integration of basic and applied sciences that provide an understanding of the impact of genetic toxicity on human populations.The goals of this meeting are to (1) build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms; (2) integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics; (3) determine how emerging technologies can lead to a better understanding of environmentally-induced genetic disease; (4) have these data serve as a foundation for human risk assessment for disease and disease prevention; and (5) aid in the support of knowledge-based regulation to protect public health and the environment. This is a meeting not to be missed. For additional information, visit the EMGS 2014 Annual Meeting website.

Safety Pharmacology Society 14th Annual Meeting, October 19–22, 2014, Washington, DC

The Safety Pharmacology Society (SPS) 14th Annual Meeting will be held October 19–22, 2014, in Washington, DC and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program will offer in-depth discussions of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two tracks, covering issues such as, Cardiovascular, Central Nervous System, Non Cardiac Ion Channels, Respiratory, Regulatory, New Assays, Peripheral Neuropathy, and an all day Plenary on Wednesday covering the Updates and Perspectives on Comprehensive In Vitro Proarrhythmia Assay (CIPA). The meeting also will offer a full day of Continuing Education courses on October 19, both on an introductory level as well as advanced courses for the expert, and the Diplomate in Safety Pharmacology (DSP) Certification exam will be held the day before the meeting on October 18. For preliminary meeting information, please visit the SPS Annual Meeting website.

American College of Toxicology’s 35th Annual Meeting, November 9–12, 2014, Orlando, Florida

The American College of Toxicology (ACT) Annual Meeting provides an ideal venue for keeping abreast of emerging trends in the discipline of toxicology, for staying connected with friends and colleagues, and for making new connections. This year’s annual meeting will include a world-class scientific program, a unique welcoming reception venue, our popular traditional poster/reception session, more social/functional events in the exhibit hall to enhance broad interactions among attendees, students, and exhibitors, and much more.The ACT Annual Meeting is the perfect blend of educational resource and interpersonal engagement for toxicologists working to stay at the top of their game. Please join us at a beautiful Orlando resort for what is sure to be another memorable ACT Annual Meeting. For more information, visit the ACT Annual Meeting website.

SOT Science News Alert March 2014

Society of Toxicologic Pathology 33rd Annual Symposium, June 22–26, 2014 

“Translational Pathology: Relevance of Toxicologic Pathology to Human Health” is the theme of the Society of Toxicologic Pathology (STP) 33rd Annual Symposium, which will be held June 22–26, 2014, at the Marriott Wardman Park Hotel in Washington, DC. Topics will include the predictive value of nonclinical models and how animal models and human endpoints inform each other, progress in the development of new nonclinical animal models and other types of models, emerging technologies that have the potential to improve translational capabilities, the role and utility of epigenetic endpoints in toxicologic pathology and their relevance to human health, how pathology outcomes inform human health assessments and regulatory decisions, and the challenges of developing translational models that provide useful information on human populations with comorbidities. By the end of this symposium, the audience will have a better understanding of current trends and data needs in translational pathology and how the field can leverage expertise and tools to meet these needs.  An interactive pre-meeting NTP Satellite Symposium will be held on Saturday, June 21, and four Continuing Education (CE) Courses will be offered on Sunday, June 22. The scientific sessions on Tuesday, June 24, have been designed in response to requests from the Federal regulatory community. US Government employees may register by June 1 to attend Tuesday sessions at no charge. Visit the 2014 STP Annual Meeting website for additional meeting details on exhibits, sessions, CE courses, and special events. Abstract Deadline is April 1.

Teratology Society 54th Annual Meeting—June 28–July 2, 2014

The theme of the 54th Annual Meeting of the Teratology Society is “Pushing the Boundaries of Birth Defects Research.” The meeting will highlight the latest scientific information and technology in birth defects and developmental disabilities research. Symposium topics include early prenatal diagnosis of birth defects, testicular dysgenesis syndrome, epigenetics, and thrombosis during pregnancy. The meeting also will feature special programs for the next generation of birth defects researchers including a workshop on building a career in developmental toxicology and a NEW Student Innovative Design Competition for improving prenatal development and child health. This competition asks students to imagine novel solutions to technical problems in the broad field of teratology—encompassing anything from a new measurement technique for exposure to environmental contaminants during pregnancy to a wireless method for assessing fetal health. The interdisciplinary nature of the Society provides unique opportunities to look broadly at complex issues. The Annual Meeting will be held June 28–July 2, 2014, in Bellevue, Washington, located on the eastside of Seattle. For more information, visit the Teratology Society Annual Meeting website

Environmental Mutagenesis and Genomics Society 45th Annual Meeting—September 13–17, 2014

The 45th Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS) will be held September 13–17, 2014, at the Hilton Orlando Lake Buena Vista, in Orlando, Florida. This year’s theme is “Integrating Environmental, Genomic, and Health Research.” The meeting will provide a forum for the latest research on DNA damage and repair, mechanisms of mutagenesis, epigenetic regulation, and their contributions to environmentally-induced human disease. In addition, current regulatory issues and risk assessment strategies will be discussed. EMGS is unique in that it provides a platform for the cross-disciplinary integration of basic and applied sciences that provide an understanding of the impact of genetic toxicity on human populations.The goals of this meeting are to (1) build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms; (2) integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics; (3) determine how emerging technologies can lead to a better understanding of environmentally-induced genetic disease; (4) have these data serve as a foundation for human risk assessment for disease and disease prevention; and (5) aid in the support of knowledge-based regulation to protect public health and the environment. This is a meeting not to be missed. For additional information, visit the EMGS 2014 Annual Meeting website.

Safety Pharmacology Society 14th Annual Meeting, October 19–22, 2014, Washington, DC 

The Safety Pharmacology Society (SPS) 14th Annual Meeting will be held October 19–22, 2014, in Washington, DC and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program will offer in-depth discussions of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two tracks, covering issues such as, Cardiovascular, Central Nervous System, Non Cardiac Ion Channels, Respiratory, Regulatory, New Assays, Peripheral Neuropathy, and an all day Plenary on Wednesday covering the Updates and Perspectives on Comprehensive In Vitro Proarrhythmia Assay (CIPA). The meeting also will offer a full day of Continuing Education courses on October 19, both on an introductory level as well as advanced courses for the expert, and the Diplomate in Safety Pharmacology (DSP) Certification exam will be held the day before the meeting on October 18. For preliminary meeting information, please visit the SPS Annual Meeting website.    

American College of Toxicology’s 35th Annual Meeting, November 9–12, 2014, Orlando, Florida—Registration Opens March 20
ACT’s Annual Meeting provides an ideal venue for keeping abreast of emerging trends in the discipline of toxicology, for staying connected with friends and colleagues, and for making new connections. This year’s annual meeting will include a world-class scientific program, a unique welcoming reception venue, our popular traditional poster/reception session, more social/functional events in the exhibit hall to enhance broad interactions among attendees, students, and exhibitors, and much more.The ACT Annual Meeting is the perfect blend of educational resource and interpersonal engagement for toxicologists working to stay at the top of their game. Please join us at a beautiful Orlando resort for what is sure to be another memorable ACT Annual Meeting. For more information, visit the ACT Annual Meeting website.

Other Meetings of Note

American College of Toxicology Course: Toxicology for Industrial and Regulatory Scientists, April 28–May 2, Gaithersburg, Maryland
This annual ACT course provides basic training in toxicology. Participants will obtain an overall understanding of the principles of toxicology and nonclinical safety evaluation. The course will include discussion of regulatory case studies and hands on analyses of nonclinical data. The course is intended to benefit individuals working with small and large molecules from chemical, biotechnology, and pharmaceutical companies, CROs and regulatory agencies interested in or currently practicing toxicology. For more information, visit the ACT website.

American College of Toxicology and Society of Toxicologic Pathology Course: Pathology for Nonpathologists, May 12–14, 2014, Rockville, Maryland

This joint ACT/STP course is held every other year. The lectures are given by highly respected pathologists with current, relevant experience in toxicologic pathology. Lectures will cover anatomy and physiology, spontaneous and chemically-induced pathological changes, clinical pathology and case examples. The knowledge gained will be immediately applicable to your day-to-day practices. Different organs or systems are featured in subsequent courses. For more information, visit the ACT website

 American College of Toxicology Course: Advanced Comprehensive Toxicology, August 10–15, 2014, Cincinnati, Ohio
The American College of Toxicology (ACT) is offering an advanced course to complement “Toxicology for Industrial and Regulatory Scientists.” In this five-day intensive course, attendees will be provided detailed descriptions of principles of toxicology, effects of xenobiotics on organ systems, mechanisms of toxicity, risk assessment, and regulatory toxicology. The content of this course will provide contemporary toxicological concepts and information that should be helpful to those seeking certification in toxicology and will be consistent with the certification examination content. The faculty consists of well-recognized experts in their field of study who are Board Certified by the American Board of Toxicology. For more information, visit the ACT website.

American College of Toxicology Course: Practical Application of Toxicology in Drug Development,September 15–19, 2014, Edinburgh, United Kingdom

This successful ACT course, taught by distinguished experts, will return in 2014 to Scotland and provide opportunities for scientists from all parts of the world to participate in a course providing basic training in toxicology. Participants will obtain an overall understanding of the principles of nonclinical safety evaluation with emphasis on the practical application of these principles and interpretation of nonclinical safety data. Regulatory toxicology in drug development will be emphasized, from both a European and a US perspective.Through the week, the students will participate in tutored group study of regulatory cases and original data from a regulatory submission, which will conclude with a half-day workshop on the last morning. For more information, visit the ACT website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert December 2013

Dear SOT Members,

Below are a number of SOT-sponsored meetings and events that may be of interest to you. For more information, contract the organizers directly.

FutureTox II CCT, January 16–17, 2014: Registration Is Open

The FutureTox II: In Vitro Data and In Silico Models for Predictive Toxicology Contemporary Concepts in Toxicology (CCT) conference will be held January 16–17, 2014, at the William and Ida Friday Center for Continuing Education, University of North Carolina, Chapel Hill, North Carolina. The conference aims to address the pathway-based strategy by bringing together basic research into a congress that integrates newer in vitro methodologies and computational (in silico) modeling approaches with advances in systems biology. An overarching goal is to clarify the usefulness and validity of new and emerging technologies and approaches so that expectations can be managed in both the regulatory and regulated scientific communities. There will be ample opportunities to network with experts in this fast changing growth area.

Some aspects of this topic were covered in the October 2012 FutureTox CCT meeting. This FutureTox II CCT will provide a forum for a detailed scientific discussion of how the biological pathways of interest will be elucidated, characterized, and qualified for pathway-based risk assessment. Breakout groups will address four key areas: Regulatory Toxicology, Liver Disease and Hepatotoxicity, Developmental/ Reproductive Toxicity, and Cancer. There is global interest in “Adverse Outcome Pathways” (AOPs) as a conceptual framework for mode-of-action approaches in these four areas. Focusing the CCT on scientific issues where new methodologies and advances can move us beyond reliance on animal models will benefit all researchers and regulators as a way of identifying key questions that need research. For additional information and to register, please visit the FutureTox II CCT website.

Teratology Society 54th Annual Meeting—Abstract Deadline February 15

The theme of the 54th Annual Meeting of the Teratology Society is “Pushing the Boundaries of Birth Defects Research” that will highlight the latest scientific information and technology in birth defects and developmental disabilities research. The meeting also will feature special programs for the next generation of birth defects researchers including a workshop on building a career in developmental toxicology and a NEW Student Innovative Design Competition for improving prenatal development and child health. This competition invites bioengineering students and other students to imagine novel solutions to technical problems in the broad field of teratology—encompassing anything from a new measurement technique for exposure to environmental contaminants during pregnancy to a wireless method for assessing fetal health. Symposia topics include early prenatal diagnosis of birth defects, testicular dysgenesis syndrome, epigenetics, and thrombosis during pregnancy. The interdisciplinary nature of the Society provides unique opportunities to look broadly at these complex issues.The 54th Annual Meeting of the Teratology Society will be held June 28–July 2, 2014, in Bellevue, Washington, located on the eastside of Seattle. For more information, visit the Teratology Society Annual Meeting website.

Society of Toxicologic Pathology Modular Education Course: Reproductive System Pathology, April 6–9, 2014, Chauncey Conference Center, Princeton, NJ

The Society of Toxicologic Pathology (STP) is pleased to announce Reproductive System Pathology, the second course in its modular education series. This series is modeled on the highly regarded and successful British Society of Toxicological Pathology (BSTP) Modular Education courses. The objective of this course is to educate individuals in the principles of toxicologic pathology of the reproductive system. The course will bring together attendees and world-renowned subject experts for didactic lectures and practical sessions including whole-slide digital images and data sets. The course will be held over three days in an environment that facilitates an intensive learning experience. Practical evaluation and interpretation of toxicologic pathology data will be emphasized.

The STP modular education courses are designed with the novice toxicologic pathologist in mind; however, pathology residents/graduate students with an interest in toxicologic pathology or experienced pathologists who desire a more in-depth review in reproductive pathology also will benefit from this course. In addition, nonpathologists with an interest in the histology, pathology, or toxicology of the reproductive system also will benefit from this course. For more updated course information and registration, please visit course website.

Society of Toxicologic Pathology 33rd Annual Symposium, June 22–26, 2014

“Translational Pathology: Relevance of Toxicologic Pathology to Human Health” is the theme of the Society of Toxicologic Pathology (STP) 33rd Annual Symposium, which will be held June 22–26, 2014, at the Marriott Wardman Park Hotel in Washington, DC. Topics will include the predictive value of nonclinical models and how animal models and human endpoints inform each other, progress in the development of new nonclinical animal models and other types of models, emerging technologies that have the potential to improve translational capabilities, the role and utility of epigenetic endpoints in toxicologic pathology and their relevance to human health, how pathology outcomes inform human health assessments and regulatory decisions, and the challenges of developing translational models that provide useful information on human populations with comorbidities. By the end of this symposium, the audience will have a better understanding of current trends and data needs in translational pathology and how the field can leverage expertise and tools to meet these needs.

The scientific sessions on Tuesday, June 24, have been designed in response to requests from the Federal regulatory community. US Government employees may register by June 1 to attend Tuesday sessions at no charge.

An interactive pre-meeting National Toxicology Program (NTP) Satellite Symposium will be held on Saturday, June 21, and four Continuing Education (CE) Courses will be offered on Sunday, June 22.

Visit the 2014 STP Annual Meeting website for additional meeting details on exhibits, sessions, CE courses, and special events.

Environmental Mutagenesis and Genomics Society 45th Annual Meeting—September 13–17

The 45th Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS) will be held September 13–17, 2014, at the Hilton Orlando Lake Buena Vista, in Orlando, Florida. This year’s theme is “Integrating Environmental, Genomic, and Health Research.” The meeting will provide a forum for the latest research on DNA damage and repair, mechanisms of mutagenesis, epigenetic regulation, and their contributions to environmentally-induced human disease. In addition, current regulatory issues and risk assessment strategies will be discussed. EMGS is unique in that it provides a platform for the cross-disciplinary integration of basic and applied sciences that provide an understanding of the impact of genetic toxicity on human populations. The goals of this meeting are to (1) build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms; (2) integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics; (3) determine how emerging technologies can lead to a better understanding of environmentally-induced genetic disease; (4) have these data serve as a foundation for human risk assessment for disease and disease prevention; and (5) aid in the support of knowledge-based regulation to protect public health and the environment. This is a meeting not to be missed. For additional information, visit the EMGS 2014 Annual Meeting website.

Safety Pharmacology Society Annual Meeting, October 19–22, 2014, Washington, DC

The Safety Pharmacology Society (SPS) 14th Annual Meeting will be held October 19–22, 2014, in Washington, DC and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program will offer in-depth discussions of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two tracks, covering issues such as, Cardiovascular, Central Nervous System, Non Cardiac Ion Channels, Respiratory, Regulatory, New Assays, Peripheral Neuropathy, and an all day Plenary on Wednesday covering the Updates and Perspectives on Comprehensive In Vitro Proarrhythmia Assay (CIPA).

The meeting also will offer a full day of Continuing Education courses on October 19, both on an introductory level as well as advanced courses for the expert, and the Diplomate SPS (DSPS) Certification exam will be held the day before the meeting on October 18. For preliminary meeting information, please visit the SPS website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert August 2013

Dear SOT Members,

Below are a number of SOT-sponsored meetings and events that may be of interest to you. For more information, contact the organizers directly.

Environmental Mutagenesis and Genomics Society 44th Annual Meeting—Late Breaking Abstract
Deadline is August 28, 2013

The Environmental Mutagenesis and Genomics Society (EMGS) is the primary professional society for scientists involved in research into environmental causes and consequences of damage to the genome and epigenome. The 44th Annual Meeting will be held September 21–25, 2013, at the Hyatt Regency Monterey, in Monterey, California. This year’s theme is “Embracing the Science of the Future through Cross-Disciplinary Research.” The Society’s Annual Meeting is unique in bringing together scientists who carry out basic research with those involved in risk estimation and regulatory concerns related to the consequences of exposure to environmental, industrial, and pharmaceutical agents. The result is a dynamic meeting that is sufficiently large to cover a broad range of contemporary topics, yet focused to facilitate interactions between students and renowned scientists in academia, government, and industry. This is a meeting not to be missed. For additional information, visit the EMGS 2013 Annual Meeting website.

Practical Application of Toxicology in Drug Development, September 9–13, 2013, Edinburgh Capital Hotel, United Kingdom

This course, taught by distinguished experts, is designed to provide a basic training in toxicology. Participants will obtain an overall understanding of the principles of nonclinical safety assessment of drug development with emphasis on the practical application of these principles and interpretation of nonclinical safety data. The course will include a discussion of regulatory case studies and a review of a drug application. This toxicology course is intended to benefit individuals working with small and large molecules from biotechnology and pharmaceutical companies, along with those from CROs and regulatory agencies who are interested in toxicology. Regulatory toxicology in drug development will be emphasized, particularly from the European perspective. To register and for more information, please visit the Practical Application of Toxicology in Drug Development website.

Safety Pharmacology Society Annual Meeting, September 16–19, 2013, Rotterdam, Netherlands

The Safety Pharmacology Society (SPS) 13th Annual Meeting will be held September 16–19, 2013, in Rotterdam, The Netherlands, and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program offers in-depth discussion of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into thematic tracks, covering issues such as, Reducing Safety Related Attrition, Expanding the Frontiers of Safety Pharmacology, Improving Support to Clinical Development, Translation of Safety Pharmacology Studies to Humans, Update and Feedback on CSRC-HESI-FDA Workshop, and a Best Practices Workshop on Comparing Safety Pharmacology as “Stand Alone” to SP-Endpoint Inclusion in Toxicology. The meeting also will offer a full day of Continuing Education courses on September 16, both on an introductory level as well as advanced courses for the expert, and the Diplomate SPS (DSPS) Certification exam will be held the day before the meeting on September 15. For preliminary meeting information, please visit the 2013 SPS Annual Meeting Website.

Product Quality Research Institute Workshop on Nanomaterial Drug Products: January 14–15, 2014

The Product Quality Research Institute (PQRI) Workshop on “Nanomaterial Drug Products: Current Experience and Management of Potential Risks” will be held January 14–15, 2014, at the US Pharmacopeia (USP) Meeting Center, Rockville, Maryland. The overarching goals and objectives of this meeting include a review of analytical science and methods for characterizing nanomaterials and discussion of their application to the characterization and quality control of drug products. Participants will share experiences and results and discuss approaches to the management of potential risks of nanomaterials in drug products starting from early drug development and throughout product lifecycle. The implications for maintaining quality, safety, and efficacy will be highlighted. The expected outcomes are to establish opportunities for collaboration between academia, industry, and government- sponsored research programs and to develop a summary report of the workshop discussions and recommendations. For more information and to register for this meeting, please visit the Workshop on Nanomaterial Drug Products website.

NANOTOX 2014, 7th International Nanotoxicology Congress: Abtract Deadline January 15, 2014

NANTOX 2014 will be held April 23–26, 2014, in Antalya,Turkey.This congress continues the series of international nanotoxicology meetings that has included: 2006 Miami, 2008 Zurich, 2010 Edinburgh, and 2012 Beijing. Commercialization of emerging nanotechnologies influences societal responses to their development and applications and demands for better evaluations of their effects on the environment and human health. Sessions of the congress will highlight the hot topics of nanotoxicology with the world-leading experts in this field. Moreover, this congress will create opportunities for participants to present and share experiences, explore new directions, and debate topics with experts from across the globe in the field of nanotoxicology. The abstract deadline is January 15, 2014. For additional information, please visit the NANOTOX 2014 website.

FutureTox II CCT: Pathways to Prediction—January 16–17, 2014

The FutureTox II: In Vitro Data and In Silico Models for Predictive Toxicology Contemporary Concepts in Toxicology (CCT) conference will be held January 16–17, 2014, at the William and Ida Friday Center for Continuing Education, University of North Carolina, Chapel Hill, North Carolina. The conference aims to address the pathway-based strategy by bringing together basic research into a congress that integrates newer in vitro methodologies and computational (in silico) modeling approaches with advances in systems biology. An overarching goal is to clarify the usefulness and validity of new and emerging technologies and approaches so that expectations can be managed in both the regulatory and regulated scientific communities. There will be ample opportunities to network with experts in this fast changing growth area.Some aspects of this topic were covered in the October 2012 FutureTox CCT meeting. This FutureTox II CCT will provide a forum for a detailed scientific discussion of how the biological pathways of interest will be elucidated, characterized, and qualified for pathway-based risk assessment. Breakout groups will address four key areas: Regulatory Toxicology, Liver Disease and Hepatotoxicity, Developmental/ Reproductive Toxicity, and Cancer. There is global interest in “Adverse Outcome Pathways” (AOPs) as a conceptual framework for mode-of-action approaches in these four areas. Focusing the CCT on scientific issues where new methodologies and advances can move us beyond reliance on animal models will benefit all researchers and regulators as a way of identifying key questions that need research. Partial travel support for graduate students and postdoctoral scholars will be available. To register and for additional information about this conference, please visit the FutureTox II website.

 

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert April 2013

Dear SOT Members,

Below are a number of SOT-sponsored meetings and events that may be of interest to you. For more information, contact the organizers directly.

Dose Response Assessment Boot Camp—May 6–10, 2013

A Dose Reponse Assessment Boot Camp will be held May 6–10, in Cincinnati, Ohio. This training opportunity is for individuals in the risk assessment or toxicology field. The course is a five-day intensive hans-on training in hazard characterization and dose response assessment. Beginners through expert toxicological risk assessors will learn advanced methods, as well as enhance their understanding and skills in the basics. Course lectures will be supplemented with daily hands-on application exercises. Upon completion of the course, participants will be able to derive and evaluate risk values and supporting documentation for both noncancer and cancer risk assessments. Five Continuing Maintenance (CM) points will be available from the American Board of Industrial Hygienists (ABIH). For additional information, please visit the Dose Response Assessment Boot Camp website.

Moving Forward in Human Risk Assessment in the Genomics Era 2.0—May 16–17, 2013

A workshop, “Moving Forward in Human Risk Assessment in the Genomics Era 2.0,” will be held on May 16–17, 2013, at the OECD Congress Center, Paris, France. This workshop will be held with the goal to review progress in human carcinogenesis safety evaluation strategies and cancer risk assessment. Experts and opinion leaders from academia, industry, and regulatory agencies in the US, EU, and Asia, will convene to discuss the utility of exploiting genomics approaches in understanding genotoxicity findings and in chemical carcinogenicity risk assessment, as well as the informatics needs to support optimal access and use of these data. Novel assay development and promising emerging data mining and modeling approaches will be discussed with particular emphasis on identifying gaps and opportunities for their application in human cancer risk assessment. This is a follow-up to a workshop held in Venice in August 2009. For additional information, please visit the Moving Forward in Human Risk Assessment in the Genomics Era 2.0 website.

New York Academy: Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment—May 29–31, 2013

The “Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment” conference will be held May 29–31, 2013, at the New York Academy of Sciences in New York City. To date, two separate groups have been studying bone marrow: toxicologists who examine chemically-induced marrow pathologies and hematologists/oncologists who investigate diseases of the marrow. This conference will bring together representatives from both fields around a jointly shared goal—to better understand, prevent, and treat myeloid malignancies. Conference sessions will combine basic science and toxicology research at the level of the bone marrow niche with clinical findings from healthy subjects and patients. Topics include the bone marrow niche structure and function, the maturation and differentiation of healthy and leukemogenic hematopoietic stem cells, cutting-edge models and tools for research, and the environmental, chemical, and genetic factors involved in the development of myeloid abnormalities, including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). The meeting will feature a series of plenary lectures, panel discussions, a poster session, and short talk presentations by early career investigators. A complete agenda and registration information is available on The New York Academy of Sciences website.

Environmental Mutagenesis and Genomics Society 44th Annual Meeting—Abstract Deadline June 1, 2013

The 44th Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS), will be held September 21–25, 2013, at the Hyatt Regency Monterey, in Monterey, California. This year’s theme is “Embracing the Science of the Future through Cross-Disciplinary Research.” The meeting provides a broad scientific forum for basic and applied researchers as well as students and teachers to review the latest information linking environmental conditions to adverse health outcomes. The emphasis of the meeting is to (i) to build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms; (ii) to integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics; (iii) to determine how interdisciplinary information can be best used to direct translational human epidemiological studies; (iv) to have these data serve as a foundation for human risk assessment for disease and disease prevention; and finally (v) to aid in the support of knowledge-based regulation to protect public health and the environment. The abstract deadline is June 1, 2013. For additional information, please visit the EMGS 44th Annual Meeting website.

Society of Toxicologic Pathology 32nd Annual Symposium—June 16–20, 2013

The Society of Toxicologic Pathology (STP) 32nd Annual Symposium, “Toxicologic Pathology of the Digestive Tract and Pancreas,” will take place June 16–20 at the Oregon Convention Center in Portland, Oregon. The 2013 STP Scientific Symposium will cover fundamental biology and recent innovations in the toxicologic pathology of the digestive tract and pancreas. The focus of this international meeting is to correlate advances in the morphologic evaluation and integration of findings in the digestive tract and pancreas with functional, cellular, and molecular knowledge in a series of plenary and poster sessions. The meeting will provide a venue for interactive discussion of the current state of knowledge in both conventional and specialized nonclinical safety studies of the digestive tract and pancreas. Program information is available on the STP 32nd Annual Symposium website.

Teratology Society 53rd Annual Meeting—June 22–26, 2013

The 53rd Annual Meeting of the Teratology Society will be held June 22–26, 2013, in Tucson, Arizona. The theme of the 2013 meeting is “Application of Cutting-Edge Technologies to Improve Assessment, Treatment, Prevention, and Communication regarding Birth Defects.” Sessions will highlight teratology research and issues that have global impact, with topics including advances in genomic sciences, application of imaging technologies, predictive developmental toxicology, diabetes and pregnancy, and chemotherapeutics. The interdisciplinary nature of the Society provides unique opportunities to look broadly at these complex issues. For more information, visit the Teratology Society 53rd Annual Meeting website.

Society of Toxicologic Pathology Modular Education Series Inaugural Course: Neuropathology—July 21–24, 2013

The Society of Toxicologic Pathology (STP) is offering “Neuropathology,” the inaugural course in the Modular Education Series, July 21–24, 2013, at the Chauncey Conference Center in Princeton, New Jersey. The course is planned in partnership with the British Society of Toxicological Pathology and with help from the STP Special Interest Group in Neuropathology. The course will include both didactic lectures and practical data and slide review sessions. Microscopic evaluation of histologic sections will be done using whole-slide digital pathology images and practical evaluation/interpretation of toxicologic pathology data will be emphasized. The modular course series is designed primarily for novice practitioners of toxicologic pathology. However, pathology residents with an interest in this specialty or experienced pathologists who desire a refresher course are welcome. In addition, nonpathologists with an interest in the normal histology, pathology, or toxicology of the nervous system also will benefit from this module. For course details and registration, please visit the STP website.

Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference: August 11–16, 2013

The Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference will be held August 11–16, 2013, in Andover, New Hampshire. This conference is a premier forum for showcasing the latest, most innovative advances in mechanistic toxicological research. For the 2013 conference, the organizers have assembled a group of world-leading experts working on areas of investigation that are highly relevant to environmental, industrial, and pharmaceutical toxicology. The topics selected are varied and of great appeal to a broad audience of scientists with an interest in toxicology. Mitochondrial diseases, epigenetics, transcriptional control of drug metabolizing enzymes, carcinogenesis, stem cells in toxicological research and novel functions of oxidative stress-related transcription factors are among the topics that will be highlighted at the conference. Applications for this meeting must be submitted by July 14, 2013. For more information, visit the Cellular & Molecluar Mechanisms of Toxicity Conference website.

Safety Pharmacology Society Annual Meeting, September 16–19, 2013

The Safety Pharmacology Society (SPS) 13th Annual Meeting will be held September 16–19, 2013, in Rotterdam, the Netherlands, and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program offers in-depth discussion of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into thematic tracks, covering issues such as, Reducing Safety Related Attrition, Expanding the Frontiers of Safety Pharmacology, Improving Support to Clinical Development, Translation of Safety Pharmacology Studies to Humans, and a Best Practices Workshop on Comparing Safety Pharmacology as “Stand Alone” to SP-Endpoint Inclusion in Toxicology. The meeting also will offer a full day of Continuing Education courses both on an introductory level as well as advanced courses for the expert. For preliminary meeting information, please visit the SPS 13th Annual Meeting website.

FutureToxII CCT: Pathways to Perdiction—January 16–17, 2014

The FutureToxII: In Vitro Data and In Silico Models for Predictive Toxicology Contemporary Concepts in Toxicology (CCT) conference wil be held January 16–17, 2014, at the William and Ida Friday Center for Continuing Education, University of North Carolina, Chapel Hill, North Carolina. The conference aims to address the pathway-based strategy by bringing together basic research into a CCT that integrates newer in vitro methodologies and computational (in silico) modeling approaches with advances in systems biology. An overarching goal is to clarify the usefulness and validity of new and emerging technologies and approaches, so that expectations can be managed in both the regulatory and regulated scientific communities. Some aspects of this topic were covered in the October 2012 FutureTox CCT. The FutureToxII CCT will provide a forum for a detailed, scientific discussion of how the biological pathways of interest will be elucidated, characterized, and qualified for pathway-based risk assessment. Breakout groups will address four key areas: Regulatory Toxicology, Liver Disease and Hepatotoxicity, Developmental/ Reproductive Toxicity, and Cancer. There is global interest in “Adverse Outcome Pathways” (AOPs) as a conceptual framework for mode-of-action approaches in these four areas. As such, focusing the CCT on scientific issues where new methodologies and advances can move us beyond reliance on animal models will benefit all researchers and regulators as a way of identifying key questions that need research. For additional information and to register, please visit the FutureToxII website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert February 2013

Dear SOT Members,

Below are a number of SOT-sponsored meetings and events that may be of interest to you. For more information, contact the organizers directly.

International Drug Abuse Research Society, Mexico City—April 15–19, 2013

The 4th International Drug Abuse Research Society meeting, Research Frontiers and Advances in Drug Addiction, will bring together basic scientists and clinical investigators from the international community to provide in-depth understanding and current knowledge concerning new conceptual insights into the CNS acting drugs, alcohol abuse, drugs of abuse, and treatment of drug addiction. This meeting will be held at the Hyatt Regency Hotel, Mexico City, from April 15–19, 2013. This meeting will address the following: (1) Role of Epigenetic, Proteomics and Metabonomics in Drug Addiction (Cocaine, Alcohol, METH), (2) Drugs of Abuse and Medication Development including Nicotine/cigarette smoking, (3) Novel neurobiological targets for the treatment of Alcoholism, (4) Substituted Amphetamines-induced Neurochemical Changes and Relationship to Neurotoxicity, (5) Drug of Abuse and Imaging Brain Structure and Function, (6) Toluene/GHB/Volatile Solvent/Inhalant/anaesthetics Neurotoxicity, (7) Marijuana/Cannabinoids, and (8) Zebrafish and drug addiction. The format of the meeting will result in a useful exchange of information not only for neurochemists/neuroscientists but also investigators from other disciplines. For additional information, please visit the International Drug Abuse Research Society meeting website.

Lessons Learned, Challenges, and Opportunities: The US Endocrine Disruptor Screening Program Workshop: April 23–24, 2013

A workshop entitled, Lessons Learned, Challenges, and Opportunities: The US Endocrine Screening Program Workshop, will be held April 23–24, 2013, at the North Carolina Biotechnology Center, Research Triangle Park, North Carolina. The purpose of this workshop is to share experience gained and lessons learned by the practitioners and laboratories that conducted the screening as well as the experience of other experts to inform the future of chemical evaluation of endocrine activity. The workshop will include a wide range of stakeholders—representatives from federal regulatory agencies, NGOs, industry, contract laboratory scientists, and academic researchers—to present, discuss, and share experience for potential improvements in Tier 1 assays, and to further advance the ability of the scientific community to assess endocrine disruption and render weight-of-evidence decisions. All interested parties are encouraged to attend—registration is open and free. More information and registration is available on the US Endocrine Disruptor Screening Program Workshop website.

Latin America Risk Assessment Workshop: April 28–May 3, 2013

As risk assessment is introduced into the registration procedure of Latin America countries, there will be an increasing need for well-trained toxicologists to better understand the process leading to sound scientifically supported risk analysis and risk management decisions. This workshop is based on the previous 20 years of experience of the Risk Assessment Summer School (RASS) sponsored by the International Union of Toxicology (IUTOX), with emphasis on learning rather than teaching. This upcoming workshop will be held at the Grande Hotel São Pedro, Águas de São Pedro, São Paulo, Brazil The objectives of the workshop are to offer young Latin American toxicologists unique opportunities (1) to broaden their knowledge and experience in the field of chemical risk assessment and (2) to better understand the data evaluation process.The workshop has been designed to include a limited number of formal lectures with plenty of time for discussions and student mentoring based on these lectures, faculty cases, and, most importantly, study cases written by the participants in advance of the workshop. For more information, visit the Latin America Risk Assessment Workshop website.

American College of Toxicology Course: April 22–26, 2013

A four and one half -day Toxicology for Industrial and Regulatory Scientists course will be conducted by the American College of Toxicology from April 22–26, 2013, in Gaithersburg, Maryland. This course, taught by distinguished experts, is designed to provide a basic training in toxicology. Participants will obtain an overall understanding of the principles of nonclinical safety evaluation with emphasis on the practical application of these principles and interpretation of nonclinical safety data. The course will include discussion of regulatory case studies and a workshop on drug development. It is intended to benefit individuals working in pharmaceutical, biotechnology and chemical/agro-chemical companies, contract research organizations (CROs), and regulatory agencies that are interested in or currently practicing toxicology. For registration and additional information, please go to the American College of Toxicology Course website.

Environmental Mutagenesis and Genomics Society 44th Annual Meeting—Abstract Deadline June 1, 2013

The 44th Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS) will be held September 21–25, 2013, at the Hyatt Regency Monterey, in Monterey, California. This year's theme is “Embracing the Science of the Future through Cross-Disciplinary Research.” The meeting provides a broad scientific forum for basic and applied researchers as well as students and teachers to review the latest information linking environmental conditions to adverse health outcomes. The emphasis of the meeting is (1) to build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms; (2) to integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics; (3) to determine how interdisciplinary information can be best used to direct translational human epidemiological studies; (4) to have these data serve as a foundation for human risk assessment for disease and disease prevention; and finally (5) to aid in the support of knowledge-based regulation to protect public health and the environment. This is a meeting not to be missed. For additional information, visit the EMGS 2013 Annual Meeting website.

14th International Neurotoxicology Association Meeting: June 9–13, 2013, The Netherlands

After 25 years, INA’s biannual meeting will be back in the Netherlands at Egmond aan Zee, June 9–13, 2013. The theme of the meeting is “Neurodevelopmental Basis of Health and Disease.” The latest advances in neurotoxicology will be shared among junior and senior scientists from all over the world. Hotel Zuiderduin, the location of the meeting, is situated in the sand dunes near Egmons aan Zee with the beaches along the North Sea within walking distance. Overall there are 11 programmed symposia. In addition, two symposia are reserved for talented young scientists and another one for “hot topics.” Abstract submission is open until April 1, 2013. The Local Organizing Committee of INA 14 includes Didima de Groot, TNO; Jan Lammers, Remco Westerink, IRAS Utrecht University; Erik de Vries, University Medical Center Groningen; Donald A. Fox, University of Houston USA (President INA 2009–2011). The current INA President is Jordi Lorens (2011–2013), University of Barcelona, Spain. This year’s conference will celebrate INA’s 25th anniversary with an exciting social program and the traditional INA soccer game. For more information see the 14th International Neurotoxicology Association website.

Society of Toxicologic Pathology 32nd Annual Symposium: June 16–20, 2013

The Society of Toxicologic Pathology (STP) 32nd Annual Symposium, “Toxicologic Pathology of the Digestive Tract and Pancreas,” will take place June 16–20 at the Oregon Convention Center in Portland, Oregon. The 2013 STP Scientific Symposium will cover fundamental biology and recent innovations in the toxicologic pathology of the digestive tract and pancreas. The focus of this international meeting is to correlate advances in the morphologic evaluation and integration of findings in the digestive tract and pancreas with functional, cellular, and molecular knowledge in a series of plenary and poster sessions. The meeting will provide a venue for interactive discussion of the current state of knowledge in both conventional and specialized nonclinical safety studies of the digestive tract and pancreas.Preliminary Program information is now available on the STP Annual Meeting website.

Teratology Society 53rd Annual Meeting: June 22–26, 2013

The 53rd Annual Meeting of the Teratology Society will be held June 22–26, 2013, in Tucson, Arizona. The theme of the 2013 meeting is “Application of Cutting-Edge Technologies to Improve Assessment, Treatment, Prevention, and Communication regarding Birth Defects.” Sessions will highlight teratology research and issues that have global impact, with topics including advances in genomic sciences, application of imaging technologies, predictive developmental toxicology, diabetes and pregnancy, and chemotherapeutics. The interdisciplinary nature of the Society provides unique opportunities to look broadly at these complex issues. For more information, visit the Teratology Society Annual Meeting website.

Gordon Research Conference on Mycotoxins & Phycotoxins: June 16–21, 2013

The 16th Gordon Research Conference on Mycotoxins & Phycotoxins will be held June 16–21, 2013, Stonehill College, Easton, Massachusetts. This conference provides an interdisciplinary and international forum of pioneering research for academic, governmental, and industrial scientists and allows for the free exchange of ideas, identification of new research opportunities, and initiation of cross-disciplinary collaborations. Contemporary themes will be explored to facilitate discussion of these natural toxins and related topics of interest. Discussion sessions will include: (1) frontiers in mycotoxin and phycotoxin research, (2) novel and emerging toxins and toxicities, (3) mechanisms of action, genomics, proteomics, and the phylogenetic basis of toxicity, (4) advances in analytical detection: use of analytical recognition elements, (5) advances in analytical detection: direct analysis of mycotoxins and phycotoxins, (6) outbreaks, exposure, and risk assessment, (7) mycotoxins and phycotoxins as therapeutic natural products, (8) strategies and regulation for prevention and control, and (9) future perspectives and directions. For more information, please visit the Gordon Research Conference on Mycotoxins & Phycotoxins website.

Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference: August 11–16, 2013

The Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference will be held August 11–16, 2013, Andover, New Hampshire. This conference is a premier forum for showcasing the latest, most innovative advances in mechanistic toxicological research. For the 2013 conference, the organizers have assembled a group of world-leading experts working on areas of investigation that are highly relevant to environmental, industrial, and pharmaceutical toxicology. The topics selected are varied and of great appeal to a broad audience of scientists with interest in toxicology. Mitochondrial diseases, epigenetics, transcriptional control of drug metabolizing enzymes, carcinogenesis, stem cells in toxicological research and novel functions of oxidative stress-related transcription factors are among the topics that will be highlighted at the conference. Applications for this meeting must be submitted by July 14, 2013. For more information, visit the conference Cellular & Molecular Mechanisms of Toxicity website.

Safety Pharmacology Society Annual Meeting, September 16–19, 2013—Rotterdam, Netherlands

The Safety Pharmacology Society (SPS) 13th Annual Meeting will be held September 16–19, 2013, in Rotterdam, The Netherlands, and will provide a dynamic forum for sharing the latest in safety pharmacology. The scientific program offers in-depth discussion of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two thematic tracks, covering issues specific to Reducing Safety Related Attrition, Expanding the Frontiers of Safety Pharmacology, Improving Support to Clinical Development, and Best Practices. The meeting will kick off with a full day of Continuing Education courses both on an introductory level as well as advanced courses for the expert. For preliminary meeting information, please visit the SPS 2013 Annual Meeting Website.

The Environmental Health of Urban Children: 4-Part Webinar Series—Beginning October 2013

Children are especially vulnerable to toxic exposures. This is of particular relevance in heavily industrialized, urban settings, e.g., Milwaukee, Wisconsin, and Haifa, Israel, which produce a range of toxic chemicals. These two port cities have a significant industrial base and possess populations that are ethnically diverse and of low socioeconomic status. In addition, these populations are exposed to chemical and physical stressors in their respective built environments and demonstrate growing environmental justice awareness. To engage scientists, environmental health professionals, and community leaders, this 4-part webinar series, which will begin in October and continue through December 2013, will focus on air pollution, a major issue for both cities, to (1) develop a platform through which stakeholders from each city will share environmental issues in their region, especially those that affect children, and what steps are being taken to mitigate those problems, (2) identify methods to create and promote healthier environments, and (3) identify next steps to enhance collaborative research and community engagement efforts to improve children’s environmental health. These webinars are co-sponsored by the Clinical and Translational Toxicology and Occupational and Public Health Specialty Sections. More information will follow via the Communiquéblog.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert October 2012

Dear SOT Members,

Below are a number of meetings and events that may be of interest to you. To learn more about these SOT-sponsored meetings and events of interest, contact the organizers directly.

SOT Sponsored-Meeting

SPS 12th Annual Meeting in Phoenix, Arizona—October 1–4, 2012

The SPS 12th Annual Meeting, which will be held October 1–4, 2012, in Phoenix, Arizona, provides a dynamic forum for sharing the latest in safety pharmacology. The scientific program offers in-depth discussion of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two thematic tracks, covering issues specific to important therapeutic areas, new regulatory developments, and new technologies. The meeting will kick off with a full day of Continuing Education courses in a broad range of topics.

CCT Meeting

FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices—October 18–19, 2012

In just a few weeks, scientists will gather to participate in the “FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices” meeting. FutureTox will address the challenges and opportunities associated with effective and efficient implementation of cutting-edge toxicity testing technologies and tools that will inform hazard prediction and risk assessment. This SOT Contemporary Concepts in Toxicology meeting will be held on October 18–19, 2012, in Arlington, Virginia. In addition to SOT, the Dow Chemical Company, US Food and Drug Administration (US FDA), ILSI Health and Environmental Sciences Institute Risk 21, Human Toxicology Project Consortium, and the National Institute of Environmental Health Sciences (NIEHS) are sponsors. FutureTox will provide information of great relevance to scientists in academia, government, and industry.

The Organizing Committee includes James S. Bus and Craig Rowlands, The Dow Chemical Company; Kim Boekelheide, Brown University; Russell S. Thomas, The Hamner Institutes for Health Sciences; Vicki L. Dellarco, US Environmental Protection Agency (US EPA); Marty Stephens, Human Toxicology Project Consortium; George P. Daston, Procter & Gamble; Suzanne Compton Fitzpatrick, US Food and Drug Administration; Raymond R. Tice, NIEHS; Robert J. Kavlock, US EPA; and Laurie C. Haws, ToxStrategies.

For general information, to review the program, and to register, visit the FutureTox website.

IUTOX Upcoming Meetings

1st Malaysian Congress of Toxicology—October 2–3, 2012

The Malaysian Society of Toxicology, one of the newest members to join IUTOX, is holding the 1st Malaysian Congress of Toxicology in Kuala, Lumpur, October 2–3, 2012. The theme of this meeting is “From Mechanistic to Regulatory Toxicology.” For additional information, please visit the 1st Malaysian Congress of Toxicology website.

ICTXIII, Seoul, Korea 2013—Session Proposal Deadline December 31, 2012

The IUTOX 13th International Congress of Toxicology (ICTXIII), which includes the IUTOX General Assembly, convenes in Seoul, Korea, June 30–July 4, 2013, at the COEX Convention and Exhibition Center. The meeting, titled Translational Toxicology from Basic Science to Chemical and Environmental Outcomes, will offer the latest advances in the science of toxicology. Eminent international speakers and leading researchers will discuss the complex issues that arise when drugs or chemicals adversely impact humans, animals, and the environment. January 31, 2013, is the deadline for abstract submissions as well for early registration. For more information, please visit the ICTXIII website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert August 2012

Dear SOT Members,

I am looking forward to seeing you at the 2013 SOT Annual Meeting, March 10–14, in historic San Antonio, Texas. Plans are well underway and many of you are now in the midst of preparing abstracts for the October 3, 2012, deadline. We are pleased that a very recent Nobel Laureate, Dr. Bruce Beutler, recipient of the 2011 Nobel Prize in Physiology and Medicine, already is scheduled for the Plenary Lecture. Dr. Beutler is Director, Center for the Genetics of Host Defense, and Professor of Immunology at the University of Texas Southwestern Medical Center, Dallas. He heads a lab that has as its goal “to advance the fundamental understanding of the genetics of immunity to aid in the treatment of infection, disorders of immunity, and autoimmunity. Failures of the immune system represent a substantial burden to society, and a tragedy for those directly affected by them.” Moreover, many of the scientific sessions at the 2013 Annual Meeting will focus on aspects of the six thematic areas, including Application of Systems Biology to Toxicology; Biomarkers for Exposure Assessment, Safety Evaluation, and Translational Medicine; Effects of Nanomaterials on Biological Systems; and Molecular Basis of Genetic Variability and Susceptibility to Toxicants. More information will follow about the next annual meeting in the months ahead. Below are a number of meetings and events that may be of interest to you. To learn more about these SOT-sponsored meetings and events of interest, contact the organizers directly.

Thank you,

William Slikker Jr.
2012–2013 SOT President

CCT Meeting

FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices—October 18–19

The “FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices” meeting will address the challenges and opportunities associated with effective and efficient implementation of cutting-edge toxicity testing technologies and tools that will inform hazard prediction and risk assessment. This SOT Contemporary Concepts in Toxicology (CCT) meeting will be held on October 18–19, 2012, in Arlington, Virginia. In addition to SOT, ILSI Health and Environmental Sciences Institute Risk 21, Human Toxicology Project Consortium, and the National Institute of Environmental Health Sciences (NIEHS) are sponsors (sponsorship opportunities are available). Three session themes are intended to stimulate more detailed dialog and understanding of “what, when, and how” considerations whereby newly emerging technologies can be constructively engaged in transition to the future vision. These themes include (a) Toxicology testing in the 21st Century (TT21c) approaches for safety assessment and expectations for effective and efficient integration into and potential transition of existing safety assessment practices; (b) TT21c approaches for exposure assessments and links to toxicity test dosimetry, with a particular focus on relationships to contextual dose-exposure considerations associated with high throughput in vitro evaluation systems; and finally (c) Reframing risk assessment practices, with an emphasis on how emerging science can best impact and reshape current risk assessment practices. For general information, to review the Program, and to register, visit the FutureTox website.

SOT Sponsored-Meetings

Environmental Mutagen Society 43rd Annual Meeting—Advance Registration Deadline: August 15

The 43rd Annual Meeting of the Environmental Mutagen Society (EMS), “EMS: The Next Generation,” will be held September 8–12, 2012, at the Hyatt Regency Bellevue, in Bellevue, Washington. The meeting provides a broad scientific forum for basic and applied researchers as well as students and teachers to review the latest information linking environmental conditions to adverse health outcomes. The emphasis of the meeting is to (1) present cutting-edge basic research in the areas of DNA repair, regulation of gene expression, epigenetics, systems biology, mutagenesis, inflammation cancer, and aging in eight symposia and seven keynote lectures; (2) present emerging “next generation” technologies and approaches in genomic research, genetic toxicology, and risk assessment; (3) feature the work of students, new and early stage investigators, and EMS members in six platform sessions; (4) network with students, mentors, and colleagues at ten Special Interest Group (SIG) meetings, two receptions and a banquet; and finally (5) entice students and new and early stage investigators to become the “Next Generation” EMS members. Keynote speakers include: Mary-Claire King, Jan Hoeijmakers, Judith Campisi, John Stamatoyannopoulos, Yosef Shiloh, Leroy Hood, Susan Wallace, and William Martin. This is a meeting not to be missed. For additional information, visit the EMS 2012 Annual Meeting website.

Eleventh International Conference on Neuroprotective Agents—September 30–October 3

The Eleventh International Conference on Neuroprotective Agents (ICNA) will be held September 30–October 3, 2012, at the Wendake Conference Center, Quebec City, Canada. The International Conference on Neuroprotective Agents has been relatively unique in its role of bringing together clinical and basic science researchers from various countries and various disciplines related to neuroprotection in an intellectually stimulating and socially relaxing environment to discuss strategies to protect the nervous system. The multidisciplinary background of the participants and the meeting’s structure (all sessions, including the poster session, are attended by all participants; meals and social events also are group functions) fosters in-depth, real-time discussion and debate. The ICNA brings together researchers involved in (1) conditions toxic to the nervous system (e.g., heat, diabetes, drugs (therapeutic and illicit), alcohol, anesthetic agents, and stroke); (2) neurodegenerative processes ‘toxic’ to the nervous system (e.g., Parkinson’s disease, Alzheimer’s disease); (3) molecular and nanotechnology techniques for understanding nervous system disorders, nervous system repair mechanisms, and neurotoxicity issues; and (4) the fields of personalized, predictive, and preventive medicine as they relate to neuroprotection. For more information including registration and housing, visit the Eleventh International Conference on Neuroprotective Agents website.

XXX Jornadas Interdisciplinarias de Toxicología, Argentina—October 23–26

The Argentine Toxicology Association is organizing its national Toxicology meeting “XXX Jornadas Argentinas Interdisciplinarias de Toxicología,” to be held in Buenos Aires, October 23–26, 2012. This event will provide a great opportunity to meet scientists from Argentina and abroad working in the field. The program covers major areas of interest in Toxicology: clinical, environmental, drugs, mechanisms, ecotoxicology, forensic, etc. In addition, three courses will be offered, including “Smoking and health: treatments, prevention,” “Current topics in Environmental Toxicology,” and “Mentoring.” Buenos Aires is by now a fashion city for tourism and a big safe metropolis (and one of the cheapest!), with a fantastic cultural life and excellent cuisine. Hope to see you! For additional information, please contact Professor Marta A. Carballo and visit the Jornadas Argentinas Interdisciplinarias de Toxicología website.

International Society of Exposure Science Annual Meeting—October 28–November 1

The 22nd annual meeting of the International Society of Exposure Science will be held October 28–November 1, 2012, in Seattle, Washington. The theme is “Lessons Learned: Contributions of Exposure Science to Environmental and Occupational Health.” The meeting will highlight the value that exposure scientists have brought, and continue to bring to environmental and occupational health policy formulation. Plenary, oral, and poster sessions will address a broad range of topics involving human exposure to chemical, physical, and biological agents in communities and the workplace. For further information, email or visit the International Society of Exposure Science Annual Meeting website.

IUTOX Meetings

IUTOX 8th CTDC8—September 10–13, 2012

IUTOX invites you to attend its next two meetings in Asia! The Thai Society of Toxicology (TST) is host to the IUTOX 8th Congress of Toxicology in Developing Countries (CTDC8) being held in Bangkok September 10–13, 2012, TST has put together an excellent program around the theme, “Sharing Toxicological Knowledge of a Healthy Life and Environment” at the beautiful venue Centara Grand at Central Plaza Ladprao Bangkok. WHO is providing an excellent day-long continuing education course titled, Human Health Risk Assessment: Toolkit for Chemical Hazards. The occasion also will be marked by a keynote address delivered by renown toxicologist, Professor Dr. HRH Chulaborn Mahidol. IUTOX is especially grateful to SOT for generously providing travel award funding, which will allow several scientists from developing and least developed countries to attend the meeting. For more information, visit the CTDC8 website.

IUTOX 13th ICTXII—June 30–July 4, 2013

The IUTOX 13th International Congress of Toxicology (ICTXIII), which includes the IUTOX General Assembly, convenes in Seoul, Korea, June 30–July 4, 2013, at the COEX Convention & Exhibition Center. The host organizers from the Korean Society of Toxicology have selected a state-of-the-art venue for this important meeting titled, Translational Toxicology from Basic Science to Chemical and Environmental Outcomes. By attending ICT XIII, attendees will learn of the latest advances in the science of toxicology, hear from eminent international speakers and leading researchers, and be able to discuss the complex issues that arise when drugs or chemicals adversely impact humans, animals, and the environment. For more information on the meeting, please visit the ICTXII website.

Please contact IUTOX Headquarters for questions about the meetings or for further information about sponsorship opportunities. We look forward to seeing you in Bangkok and Seoul!

Webinars of Note

Safety Pharmacology Society Webinars: The Assessment of Safety Pharmacology Endpoints in Toxicology Studies

There is a growing interest for inclusion of safety pharmacology endpoints in toxicology studies in order to:

  • Address ICH S7A & S7B requirements
  • Achieve the 3Rs, better utilize resources, and control costs
  • Generate additional data after repeated dosing

This trend includes both investigative and regulatory toxicology studies and has been facilitated by the advent of new technologies improving data quality and non-invasive measurements.

SPS will host a series of four webinars in September 2012 focused on specific areas of safety pharmacology: CV, CNS, Respiratory, and Supplementary Studies. Please visit the SPS Webinar webpage for specific dates and times. Each webinar will explore the advantages and disadvantages of adding these endpoints in toxicology studies and the impact on drug discovery and development. Webinar participants are encouraged to actively engage in discussion after presentations from an expert panel. The results of these webinars, along with the outcome from an upcoming SPS industry survey, will serve to create a white paper on best practices, industry trends, opportunities, and pitfalls when including safety pharmacology into toxicology studies. Results will be shared at the 2012 SPS Annual Meeting in Phoenix this October, and potentially at the SOT 2013 Annual Meeting in March.

SOT Science News Alert May 2012

Dear SOT Members,

I am forwarding a message received from Seymour Garte of the Center for Scientific Review (CSR) announcing that the Special Emphasis Panel (SEP) called Systemic Injury by Environmental Exposure (SIEE) has been reinstated to review grant applications “in the fields of Environmental Health and Toxicology.” SOT leadership worked with the CSR for a number of years regarding the need for a Study Section focused on toxicology. This is the next step in that process and builds on the efforts and accomplishments of many individuals. You are encouraged to submit your proposals to this SIEE and the guidelines for submission are included in Dr. Garte’s message below.

Thank you,

William Slikker Jr, PhD, ATS
2012–2013 SOT President

Systemic Injury by Environmental Exposure (SIEE) Reinstated

On January 13, 2012, an expert Working Group met in Bethesda to advise CSR on how to proceed with the review of grant applications in the fields of Environmental Health and Toxicology. That Working Group agreed on a recommendation to reconstitute the Special Emphasis Panel called Systemic Injury by Environmental Exposure as a chartered Study Section in the DKUS IRG. The Working Group also developed a set of guidelines to define the scope of the new study section.

Following the Working Group meeting, senior staff at CSR have discussed and considered these recommendations. One consideration was that new Study Sections are generally established directly after the successful conclusion of a trial SEP. Since it has been three years since the final meeting of the SIEE trial SEP, it has been decided to reconstitute SIEE as a SEP, to meet for 1 to 3 review cycles, before moving on to request permanent chartered status. This will give the scientific community time to generate and submit a sufficient number of high quality applications for review, and will give CSR and its Advisory Council sufficient data to ensure the viability of the new Study Section in the current timeframe. Meanwhile, the new SEP will function as a regular study section dedicated to review of environmental health and toxicology applications.

At this point, CSR staff has begun the process of preparation for the return of SIEE, including recruitment of reviewers, setting dates for meetings, etc. We anticipate the first meeting to be in February 2013 to review applications submitted for the October/November 2012 deadlines.

We encourage potential applicants in the field of toxicology and environmental health sciences to consider submitting applications directed to this study section, and to view the new guidelines for SIEE.

Applicants are strongly advised to include a cover letter asking for their applications to be reviewed in the SIEE Special Emphasis Panel (SEP). The future success of this study section will largely depend on the response from the research community in this vital discipline. Best of luck to all applicants.

Seymour Garte, PhD
Director
Division of Physiological and Pathological Sciences
Center for Scientific Review
National Institutes of Health
6701 Rockledge Dr. MSC 7812
Bethesda MD 20892
Tel: 301.435.1260
Fax: 301.480.2644

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert April 2012

It has been my pleasure to serve as the 2011–2012 SOT President and to help develop and launch the SOT 2012–2015 Strategic Plan. Our commitment to aligning our programs and activities with our strategic priorities is demonstrated through the Society’s financial support and/or endorsement of meetings held around the globe. In addition to the two SOT Contemporary Concepts in Toxicology (CCT) conferences listed below, the meetings help to foster our six key priorities:

  • Be a Forum for Novel Discoveries and Approaches Related to Toxicology
  • Increase the Impact of Toxicology on Human Health and Disease Prevention
  • Strengthen Partnerships with Scientific and Health-Based Organizations Worldwide
  • Increase Visibility of SOT as a Global Resource and its Members
  • Increase Reliance of Policy, Regulatory and Corporate Decision Makers on Science of Toxicology
  • Attract, Train, and Retain Toxicologists

Please see the information below and contact the organizers directly if you wish to participate.

You are encouraged to seek support for your meetings through the funding available for Non-SOT Meeting support and Global Initiative Funding.

Moreover, I know that many of you are polishing the SOT 2013 Annual Meeting proposals you will be submitting online by April 30 at 11:59 pm EDT. I look forward to seeing you in San Antonio, Texas, March 10–14 and to attending the scientific sessions you are developing.

Jon Cook, PhD, ATS
2011–2012 SOT President

SOT-Sponsored Meetings

SOT Contemporary Concepts in Toxicology (CCT) Meetings

Building for Better Decisions: Multi-Scale Integration of Human Health and Environmental Data—Register at a Reduced Rate!

The Building for Better Decisions (B4BD) Contemporary Concepts in Toxicology (CCT) meeting will be held May 8–11, 2012, at the US EPA Campus, Research Triangle Park, North Carolina. Toxicologists and other environmental scientists now face the challenge of integrating increasingly complex data to translate their work and predict adverse outcomes in various applications. Thisopen, international workshop provides a unique opportunity to discuss the state of the science and data management and model interoperability needs with software engineers and database architects. Participants will identify and discuss new ways to advance new methods and technologies for the following key areas of: Exposure, Transport, and Transformation; Ecological Risk, Ecosystem Services, and Climate Change; Dose Response, Tox21, and Risk; Life Cycle / Multi-Criteria Assessment and Cost: Benefit Analysis; and Information Technology. A poster session with reception will feature nearly 50 posters submitted under these same themes. Both the posters and breakout group discussions will serve as the basis for perspective papers on the state of the science for each discipline and a set of recommendations for how to advance integrated modeling and interoperability. If you have not already done so, please register now to take advantage of the reduced registration fees.  

PPTOX III: Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms—May 14–16

“PPTOX III: Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms,” will be held May 14–16 in Paris, France. This international conference will focus on the role of environmental exposures and nutrients during development on subsequent diseases/dysfunctions later in life. The goal of the PPTOX (Prenatal Programming and Toxicity) conference is to examine the animal and human data supporting this hypothesis (developmental basis of disease) by disease, target organ, and mechanism in order to review the current state of the literature and to identify mechanisms for the effects as well as to identify research gaps and challenges and to integrate the basic and applied science. PPTOX III will include 130 abstracts, 12 awards, and 43 speakers. For additional information, please visit the PPTOX III website.

SOT Sponsored and Endorsed Non-SOT Meetings

Eurotox 2012 in Stockholm, June 17–20—Late Breaking Abstract Submission Deadline June 6

Eurotox 2012, the 48th EUROTOX Congress, will take place in Stockholm, Sweden, June 17–20, 2012. The scientific program is designed with input from toxicologists from all parts of Europe and incorporates the cutting edge of toxicology and safety science. The congress will take place at the Stockholm Waterfront Congress Centre, which offers fantastic facilities for all activities including the continuing education program, exhibitions, and poster viewing. The scientific program is the result of a careful review of a large number of session proposals. There will be speakers from 20 different countries and presentations that cover the most up-to-date studies and results in the broad field of toxicology. The program includes 17 symposia, 7 workshops, oral sessions, keynote lectures, highlighted lectures, the Eurotox-SOT debate, a hot-issues debate, poster display, and the celebration of 50 years of toxicology in Europe and much more. The Eurotox 2012 congress offers six continuing education courses that connect to the theme of the congress “Safety Science Serving Society” and thus consider risk/safety assessment aspects to varying extent. The courses start at a basic level and end at pointing out emerging issues within the field. In order to support learning, all courses will encourage active participation of participants, for example by group discussions. Visit the Eurotox 2012 website to see the detailed scientific program and continuing educational courses as well as to submit late breaking abstracts and to register for the congress.

Teratology Society 52nd Annual Meeting—June 23–27

The 52nd Annual Meeting of the Teratology Society will be held June 23–27, 2012, in Baltimore, Maryland. The 2012 meeting theme is “Global Perspectives in Teratology” and will highlight birth defects research and issues, which have global impact. Topics include maternal/fetal health in developing countries, impacts of nuclear disasters on reproduction and development, effects of Vitamin D deficiency on maternal and fetal health, international controversies concerning hazard- versus risk-based regulations, and novel computational approaches for assessing safety during pregnancy and development. The interdisciplinary nature of the Society provides unique opportunities to look broadly at these complex issues. For more information, visit the Teratology Society Annual Meeting website.

Upcoming Training Opportunities from Toxicology Excellence for Risk Assessment (TERA)

Toxicology Excellence for Risk Assessment (TERA) has 2 upcoming Dose-Response Assessment Boot Camps. TERA’s Dose-Response Assessment Boot Camp is an intensive, hands-on training course in hazard characterization and dose-response assessment. TERA has trained over 300 people from 11 different countries in the last 5 years! Upcoming courses are a 4-day Course: July 23–26, 2012, in Sydney, Australia (following the World Congress on Risk) and a 5-Day Course: October 15–19, 2012, in Washington, DC. For more details visit the TERA courses website

TERA is also offering a webinar entitled “WEBINAR: Practitioner’s Guide to Risk Assessment for Developmental and Reproductive Toxicology (DART).” The webinar will be held on Wednesday, June 13, 2012, from 1:00 pm–5:00 pm EDT. The course is intended for health scientists and product stewardship professionals who need to consider the potential for reproductive and developmental effects of their chemicals or products. Learning objectives of the course include: interpreting adversity and clinical relevance of DART endpoints; applying dose-response techniques; evaluating mode of action and human relevance; optimizing testing needs and strategies; and understanding key concepts in current risk assessment guidance for DART. For more details visit the TERA webinars website

For more information on any of the training offered by TERA, please contact: Patricia Nance at 513.542.7475, Ext 25.

Society of Toxicologic Pathology 31st Annual Symposium June 24–28

“Mechanisms of Toxicity” is the theme of the Society of Toxicologic Pathology (STP) 31st Annual Symposium to be held June 24–28, 2012, at the Boston Marriott Copley Place. The global regulatory agencies and the general public require outstanding scientific rigor and quality in the human risk assessment of xenobiotics. To meet these demands, the toxicology and pathology professions are positioned to take advantage of key learnings captured from major advances in the molecular understanding of host defense, disease, and toxicity processes. The purpose of the 2012 Annual Symposium will be to examine the mechanism of toxicity in six general sessions covering tissue injury related to 1) host factors; 2) chemical structure; 3) xenobiotic cellular targets (on- and off-target); 4) new technologies (e.g., nanotechnology, siRNA therapy, and immunoconjugates); 5) cellular organelle specific effects; and 6) high profile environmental chemicals and consumer products. For addition information, please visit the STP 31st Annual Symposium website.

Environmental Mutagen Society 43rd Annual Meeting—Abstract Deadline May 15

The 43rd Annual Meeting of the Environmental Mutagen Society (EMS), “EMS: The Next Generation,” will be held September 8–12, 2012, at the Hyatt Regency Bellevue, in Bellevue, Washington. The meeting provides a broad scientific forum for basic and applied researchers as well as students and teachers to review the latest information linking environmental conditions to adverse health outcomes. The emphasis of the meeting is to 1) present cutting-edge basic research in the areas of DNA repair, regulation of gene expression, epigenetics, systems biology, mutagenesis, inflammation cancer, and aging in eight symposia and seven keynote lectures; 2) present emerging “next generation” technologies and approaches in genomic research, genetic toxicology, and risk assessment; 3) feature the work of students, new and early stage investigators, and EMS members in six platform sessions; 4) network with students, mentors and colleagues at ten Special Interest Group (SIG) meetings, two receptions and a banquet; and finally 5) entice students and new and early stage investigators to become the “Next Generation” EMS members. This is a meeting not to be missed. For additional information, visit the EMS 2012 Annual Meeting website.

8th Congress of Toxicology in Developing Countries—Abstract Deadline April 30 (TODAY)

The 8th Congress of Toxicology in Developing Countries (8CTDC) will be held from September 10–13, 2012, in Bangkok, Thailand. The 8CTDC will provide an opportunity to cover a wide range of topics representing the latest scientific advancements as well as toxicological problems in developing countries. Present your work by submitting an abstract by the submission deadline of April 30, 2012. Abstract submission instructions can be found on the 8CTDC website. Those who submit an abstract may be eligible to receive a travel award to assist in attending this world class meeting. Full information and award application can be found on the IUTOX website. A scientific program is planned that will allow attendees to participate and benefit from the exchange of views and ideas from around the world. Due to its natural beauty and rich cultural heritage, Bangkok is a unique city with lots to offer its visitors. Register for 8CTDC by June 2, 2012, to receive discounted registration rates. Full meeting details may be found on the 8CTDC website.

Safety Pharmacology Society, October 1–4—Meeting Abstract Deadline June 15

The SPS 12th Annual Meeting, which will be held October 1–4, 2012, in Phoenix, Arizona provides a dynamic forum for sharing the latest in safety pharmacology. The scientific program offers in-depth discussion of relevant topics to keep you “in the know.” This meeting will feature a diverse range of scientific sessions organized into two thematic tracks and covering issues specific to important therapeutic areas, new regulatory developments, and new technologies. Please consider submitting an abstract for presentation as a poster by the deadline of June 15, 2012. From these submissions, a number will be selected for short oral communications. The meeting will kick off with a full day of Continuing Education courses in a broad range of topics. In an effort to support attendance from our younger colleagues, please note that SPS offers Student and Junior Investigator Travel Awards. Register now to receive the Early Bird rate.

2012 Careers in Toxicology Workshop—July 18–20

The Curriculum in Toxicology at the University of North Carolina at Chapel Hill will hold a workshop on career tracks in toxicology at the North Carolina Biotechnology Center in Research Triangle Park, North Carolina. This workshop is targeted to students enrolled in graduate training programs in toxicology. Its aim is to expose trainees to employment paths beyond traditional academic research settings, including research and regulatory careers in the private and public sectors. The program will include presentations by toxicologists in senior positions in the pharmaceutical, consumer products, energy and chemical industries, as well as government agencies and private consulting firms. Additional information will be available on the NCbiotech website.

2nd International Conference on Environmental Pollution, Restoration, and Management: Hanoi, March 2013—Abstract Submission Open

This international conference will be held in Hanoi, Vietnam, March 4–8, 2013. In addition to SOT, the sponsoring organizations include the Society of Environmental Toxicology and Chemistry (SETAC), Loyola University of Chicago, and Hanoi University of Science. According to the conference organizers, “this conference is important for understanding and solving environmental problems and is critical to scientists, managers, and students in developing countries.” Participants from 54 different countries attended the first conference, and this second conference is anticipated to provide great opportunities for research and education collaborations for students and scientists around the world. The abstract submission site is now open. More information can be found on the conference website or contact Tham Hoang/Rachel Pryor, or Nhan Dang.

Other Meetings of Interest

Pathology for Nonpathologists May 14–16

The American College of Toxicology (ACT) and the Society of Toxicologic Pathology will co-sponsor “Pathology for Nonpathologists 2012,” May 14–16 in Falls Church, Virginia. Presentations by highly respected pathologists with current relevant experience in toxicologic pathology will include the hepatobiliary, urinary, reproductive, cardiovascular, and respiratory systems. The lectures will cover anatomy and physiology, spontaneous, and chemically induced pathological changes, clinical pathology and case examples. The knowledge gained will be immediately applicable to your day-to-day practices. Please see the ACT website for registration and further information.

Short Course on Industrial Toxicology and Pathology July 23–27

The 9th Biennial Short Course on Industrial Toxicology and Pathology, sponsored by the University of Illinois College of Veterinary Medicine and co-sponsored by the Society of Toxicologic Pathology, will be held July 23–27 in Champaign, Illinois.

Session One: Toxicology & Pathology in Drug Discovery and Development including Emerging Issue: Metabolic Syndrome. This session is designed for toxicologists, pathologists, and other professionals working in the pharmaceutical, chemical, and consumer products fields with a primary emphasis on drug discovery and development. The session also is applicable to professionals responsible for design and evaluation, safety assessment, and regulatory issues associated with product development in industry, government, and contract laboratories. The objective of the session is to address current global issues in the rapidly advancing fields of toxicology and pathology; to enhance attendees’ skills in interpreting animal safety studies; to facilitate interactions with federal regulatory agencies; and to provide networking opportunities.

Session Two: Contemporary Concepts in Target Organ Toxicologic Pathology. Renal and Respiratory Systems: This session is designed for pathologists, toxicologists, and other professionals working in toxicology-related fields such as the pharmaceutical, chemical, consumer, and environmental areas. The objective of the session is to provide an understanding of the basis and manifestations of target organ responses to xenobiotic injury as well as cutting-edge concepts. Further information available on the course website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert January 2012

SOT 51st Annual Meeting March 11–15, 2012, San Francisco

SOT has been preparing for months to bring you the SOT 51st Annual Meeting, to be held March 11–15, 2012, in my hometown, spectacular San Francisco, California. I am confident that you liked what you saw as you paged through the Preliminary Program and are already planning your itinerary to include many of the featured sessions and events that make this meeting memorable each year. I look forward to greeting you at the Awards Ceremony on Sunday, March 11 and to seeing you at the roundtables, workshops, and symposiums and in the ToxExpo Exhibit Hall. If you haven’t registered for the meeting, I encourage you to take advantage of the Early Bird Registration that closes on January 27, 2012. For additional information, visit the SOT 2012 Annual Meeting website. See you in San Francisco!

In addition, SOT is committed to strengthening partnerships with other scientific and health-based organizations and sponsors meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Jon C. Cook
SOT President

SOT-Sponsored Meetings

Evidence-Based Toxicology for the 21st Century: Opportunities and Challenges—January 24–25

This workshop, hosted by the multi-stakeholder Evidence-based Toxicology Collaboration (EBTC), will be held January 24–25, 2012, at the US Environmental Protection Agency, Research Triangle Park, North Carolina, and feature sessions on validation of high throughput methods, priority areas for deploying the new methods, case studies of past and current EBT related efforts, and governance and work processes of the EBTC as it moves forward. Primary presentations, followed by invited responses from several individuals, will include ample time for questions and answers. For program and registration information go to the EBTC website and/or send an email.

Individual Variability NAS Workshop—April 18–19

The next Emerging Science for Environmental Health Decisions Workshop, “Individual Variability,” will be held April 18–19, 2012, at the National Academies (NAS), Washington, DC. This workshop will explore new and innovative approaches to characterizing individual variability arising from endogenous, biological factors and its impact on susceptibility to risks from environmental exposures. The workshop also will consider the implications of emerging approaches to policies designed to address susceptibility in public health and risk assessment. The workshops are sponsored by The National Institute of Environmental Health Sciences (NIEHS) that asked NAS to facilitate communication among government, industry, environmental groups, and the academic community about scientific advances that may be used in the identification, quantification, and control of environmental impacts on human health. For more information, visit the NAS Workshop.

Toxicology for Industrial and Regulatory Scientists—April 23–27

The American College of Toxicology (ACT) Course, “Toxicology for Industrial and Regulatory Scientists,” will be held April 23–27, 2012, Falls Church, Virginia. The course, taught by distinguished experts, is designed to provide a basic training in toxicology. Participants will obtain an overall understanding of the principles of nonclinical safety evaluation with an emphasis on the practical application of these principles and interpretation of nonclinical safety data. The course will include discussion of regulatory case studies and a workshop. For more information, please visit the ACT website.

Building for Better Decisions: Multi-Scale Integration of Human Health and Environmental Data—May 8–11

“Building for Better Decisions (B4BD): Multi-Scale Integration of Human Health and Environmental Health” SOT Contemporary Concepts in Toxicology (CCT) meeting will be held May 8–11, 2012, at the US Environmental Protection Agency, Research Triangle Park, North Carolina. This international conference will provide a unique opportunity to convene scientists from different sectors (e.g., government, industry, and academia), across the exposure-dose-response continuum for both ecological and health endpoints, and from other communities (e.g., clinical/biomedical informatics, defense, intelligence) to discuss data interoperability, data integration, data management and model interface needs with software developers, software engineers, database architects and administrators, and data analysts. Experts from these arenas will be brought together to discuss and explore the requirements for data accessibility, data storage, data management, data analysis, and data interoperability that are becoming increasingly critical for computational modeling, research, and regulatory decision making. Technology and design issues that transcend disciplines and that could exercise the science and organizational infrastructure required to ensure the success of these scientific endeavors and data integration also will be examined. It is envisioned that the presentations of perspectives from these arenas will help to advance the application of data from emerging technologies in an integrated fashion to inform health and environmental-based decision making. For further program and registration information, please visit the CCT B4BD website.

PPTOX III Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms—May 14–16

“Prenatal Programming and Toxicity III (PPTOX III) Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms” SOT Contemporary Concepts in Toxicology (CCT) meeting will be held May 14–16, 2012, in Paris, France. This international conference will focus on the role of environmental exposures and nutrients during development on subsequent diseases/dysfunctions later in life. The goal of the conference is to examine the animal and human data supporting this hypothesis (developmental basis of disease) by disease, organ system, and mechanism in order to review the current state of the literature and to identify mechanisms for the effects as well as to identify research gaps and challenges and to integrate the basic and applied science. The following items will be discussed during the meeting: new epidemiological and toxicological evidence for the contribution of developmental exposure to adult disease; predictive value of animal and alternative models; the essential contribution of epigenetics to programming; the effect of chemical or physical insults as well as nutritional imbalance on stem cells, and the long path from discovery to regulation. The outcomes of this meeting will include updated information on the state of the front-line science in this field, expanded contact, and possible development of collaborations among participants. For further program and registration information, please visit the CCT PPTOX III website.

The Contribution of Epigenetics in Pediatric Environmental Health—May 30–June 1, 2012

The Children’s Environmental Health Network (CEHN) will convene a research conference titled “The Contribution of Epigenetics in Pediatric Environmental Health,” May 30–June 1, 2012, at the Stanford Court Renaissance Hotel in San Francisco, California This event will help mark CEHN’s 20th Anniversary and highlight the role of epigenetics in determining the impact of the environment on pediatric disease and children’s current and future health. The abstract submission deadline is 11:59 pm EDT, March 2, 2012. To view the Call for Abstracts, obtain further event details, or to register to attend, please visit the CEHN 2012 Research Conference website.

GRC on Environmental Endocrine Disruption—June 3–8

The 2012 Gordon Research Conference (GRC) on “Environmental Endocrine Disruption” will provide investigators with the latest research findings in the field. The conference will be held June 3–8, 2012, Mount Snow, West Dover Vermont. Sessions will include talks on public policy; links between endocrine disruptors and disease processes; epidemiological studies; outcomes for wildlife and ecosystems; and underlying mechanisms of action of endocrine disruptors. It is anticipated that the collegial and cooperative atmosphere that has traditionally characterized this conference will provide the perfect setting for the intellectual development and collegial discussions to further research in this field. The GRC will be preceded by a Gordon-Kenan Research Seminar (GRS) for trainee-level investigators. More details can be found at the GRC website.

Teratology Society 52nd Annual Meeting—June 23–27

The Teratology Society’s (TS) 52nd Annual Meeting will be held June 23–27, 2012, at the Marriott Baltimore Waterfront Hotel in Baltimore, Maryland. The theme of the 2012 meeting is “Global Perspectives in Teratology” and will highlight teratology research and issues which have global impact, with topics including maternal/fetal health in developing countries, impact of nuclear disasters on congenital malformations, Vitamin D deficiency in pregnancy and neonatal development, international differences in hazard vs risk-based regulation, and novel computational approaches for the assessment of chemical safety. There also will be joint sessions with OTIS and NBTS covering latent functional effects of developmental exposures, effects of methamphetamines, and strategies to reduce the impact of known teratogens, as well as Continuing Education courses on Maternal/Fetal Immunology, Infections during Pregnancy, and the Role of Micro-RNAs in Human Disease and Teratogenesis.

In addition, the 2012 will meeting will feature several first time-ever sessions:

  • Grant Funding Workshop with agency program officers
  • All-day workshop on Issues in Pharmaceutical Safety Testing and Labeling
  • Roundtable Session with the Society of Maternal Fetal Medicine
  • Special workshop with investigators from the National Children’s Study

Share your work by submitting an abstract for poster or platform presentation before the February 15, 2012, deadline, and take advantage of the Early Bird Registration rates and register before the February 22, 2012, deadline. For additional information please visit the TS 52nd Annual Meeting website.

Society of Toxicologic Pathology 31st Annual Symposium—June 24–28

“Mechanisms of Toxicity” is the theme of the Society of Toxicologic Pathology (STP) 31st Annual Symposium to be held June 24–28, 2012, in Boston, Massachusetts. The global regulatory agencies and the general public require outstanding scientific rigor and quality in the human risk assessment of xenobiotics. To meet these demands, the toxicology and pathology professions are positioned to take advantage of key learnings captured from major advances in the molecular understanding of host defense, disease, and toxicity processes. The purpose of the 2012 Annual Symposium will be to examine the mechanism of toxicity in six general sessions covering tissue injury related to 1) host factors, 2) chemical structure, 3) xenobiotic cellular targets (on- and off-target), 4) new technologies (e.g., nanotechnology, siRNA therapy, and immunoconjugates), 5) cellular organelle specific effects, and 6) high profile environmental chemicals and consumer products. For addition information, please visit the STP 31st Annual Symposium website.

Mechanisms of Neurotoxicity and Implications for Neurological Disorders (Barcelona)—July 13

This symposium is a Satellite Event of the Federation of European Neuroscience Societies (FENS) Forum 2012, Barcelona, which will be held July 14–18 in Barcelona. The symposium focuses on the mechanisms of neurotoxicity potentially involved in neurodegenerative diseases and/or neurodevelopmental disorders. Aspects, including gene-environment interactions, specific cellular alterations, and neurodevelopmental implications will be covered by the selected speakers that are internationally recognized experts in the field. Additional oral presentations on the most relevant topics will be selected from the abstracts submitted, and priority will be given to young investigators. Other abstracts will be presented in a poster session. The event is promoted by the International Neurotoxicology Association (INA) and the Neurotoxicity Society (NTS), and is also supported by the University of Barcelona, the Karolinska Institute, and the IDIBELL Research Institute. For additional information, visit the FENS Forum 2012 website.

Xenobiotic Receptors: Physiological Regulators and Mediators of Toxicity, 31st Summer Symposium in Molecular Biology—July 22–24

The 31st Summer Symposium in Molecular Biology at Penn State’s University Park Campus, will be held at the Nittany Lion Inn at State College, Pennsylvania, and is certain to be of broad interest to scientists involved in all fields of basic research as well as those engaged as pharmaceutical and chemical industry scientists and government regulators. This meeting will bring together preeminent scientists to focus on the most recent advances in xenobiotic receptor research that underlie their biological modes of action, and assess the impact of these processes on human health, chemical disposition, and toxicity. Special emphasis will include focus on the receptors—CAR/PXR, the PPARs, AhR, and highlight technological advances in comprehensive pathway analysis of these biological effectors. For more information and to register, please visit the 31st Summer Symposium website.

Occupational and Environmental Factors in Neurological Disease Conference—November 1

The University of California San Francisco (UCSF) Division of Occupational and Environmental Medicine is hosting a special one-day conference, “Occupational and Environmental Factors in Neurological Disease” to take place on Thursday, November 1, 2012, at Fisherman’s Wharf Holiday Inn in San Francisco, California. The conference addresses an important topic with the goal of maximizing interactions among occupational and environmental health clinicians, researchers, and public health policymakers. In addition, a hands-on training workshop the afternoon before the main meeting day will provide an important additional educational training opportunity for non-neurologists who are clinical occupational practitioners. For details on conference registration, please visit the Office of Continuing Medical Education website.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert August 2011

SOT 51st Annual Meeting March 11–15, 2012, San Francisco—October 3 Abstract Deadline Approaching

As the summer months wind down and seasons begin to change, you look at the year ahead and plan for those activities that are of greatest interest and importance to you. For SOT members, one of these major events is the SOT Annual Meeting, which will be held in spectacular San Francisco, March 11–15, 2012. You are invited to submit abstracts for presentation to this largest toxicology meeting and exhibition in the world. We expect to attract more than 7,000 scientists from industry, academia, and government to the convention.

Why Should You Submit an Abstract? Below are just a few of the reasons for you to consider:

  • Contribute your toxicologic research to the leading international forum for toxicologists.
  • Present cutting-edge research that could potentially have a significant impact on the practice of toxicology.
  • Provide attendees with the opportunity to learn about emerging fields and how they apply to toxicology.
  • Open dialogue among your scientific colleagues to effectively develop strategies for active involvement in other areas of toxicology.
  • Gain recognition among your peers by having your research published in The Toxicologist.

For additional information, visit the SOT 2012 Annual Meeting Web site.

I look forward to greeting you in San Francisco!

In addition, SOT is committed to strengthening partnerships with other scientific and health-based organizations and sponsors meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Jon C. Cook
SOT President

SOT-Sponsored Meetings

2011 Genetic Toxicology Association Annual Meeting—September 14–15

The Genetic Toxicology Association (GTA) Annual Meeting, entitled “Scientific and Regulatory Issues in Genetic Toxicology,” will be held September 14–15, 2011, on the campus of the University of Delaware, Newark, Delaware. The program will offer a keynote lecture, symposia, workshops, networking opportunities, and a poster session (including a student and young investigator competition). Topics include the 3Rs- replacement, refinement, and reduction of the use of animals in research, academic cancer research, genotoxic impurities in drugs, nanoparticles, biotherapeutics, as well as other current initiatives in genetic toxicology. For further information, go the GTA Meeting Web site.

Third TIES Conference—September 15–16

The third Toxicogenomics Integrated with Environmental Sciences (TIES) Conference will take place September 15–16, 2011, at the University of North Carolina at Chapel Hill (UNC) William and Ida Friday Center for Continuing Education in Chapel Hill, North Carolina. The two-day event is sponsored by the National Institute of Environmental Health Sciences, the U.S. Food and Drug Administration, National Center for Toxicological Research, the SAS Institute, and UNC. The international meeting will focus on how bioinformatics and emerging technologies help researchers better understand the environmental influences behind the development and progression of human disease. The conference theme is “The Biology and Bioinformatics Behind Environmental and Toxicologic Influences,” and will feature oral presentations and a poster session. For additional information, visit the TIES Conference Web Site.

SPS 11th Annual Meeting—September 19–22, Innsbruck, Austria

The 11th Annual Meeting of the Safety Pharmacology Society (SPS) will be held September 19–22, 2011, in Innsbruck, Austria. The 2011 Scientific Program features a diverse range of scientific sessions organized into three thematic tracks, enabling attendees to stay abreast of new content and developments in all areas of safety pharmacology: Academic-Industrial-Regulatory Interfaces; Applied Technology; and Preclinical-Clinical Translation. The Keynote Address, “Assessment of Nephrotoxicity—What We Know and What We Still Need to Know!” will be delivered by Walter Pfaller, M.D., Professor, Innsbruck Medical University, Austria. The 2011 meeting also offers a broad Continuing Education program, both on an introductory level as well as advanced courses for the more experienced scientist. The SPS Annual Meeting and Exhibition draws nearly 500 Safety Pharmacologists from around the globe to share and discuss the latest developments in research and technology. The SPS Exhibition Hall showcases the latest in technology and services for the safety pharmacologist.

NRC Emerging Science for Environmental Health Decisions Workshop: Applying 21st Century Toxicology to Green Chemical and Material Design—September 20–21

The National Research Council’s (NRC) Standing Committee on Emerging Science for Environmental Health Decisions, sponsored by NIEHS, organizes a number of timely workshops that address questions that are highly significant to toxicologists, risk assessors and public health professionals. The next workshop will take place September 20–21, 2011, in Washington, D.C. You can register on-line now for “Applying 21st Century Toxicology to Green Chemical and Material Design.” Subscribe to receive newsletters and updates on the workshops and other related activities. The workshops are free, open to the public, and posted online after the event. For more information visit the Emerging Science for Environmental Health Decisions Web site.

Dose-Response Assessment Boot Camp—September 19–23, 2011

The next Dose-Response Assessment Boot Camp will be held September 19–23, in Cincinnati, Ohio. Developed by Toxicology Excellence for Risk Assessment (TERA), this course is an intensive hands-on training in hazard characterization and dose-response assessment. Beginners through expert toxicological risk assessors will learn advanced methods, as well as enhance their understanding and skills in the basics. Upon completion of the course, participants will be able to derive and evaluate risk values and supporting documentation for both non-cancer and cancer risk assessments. For more information, visit the the TERA Web site.

42nd EMS Annual Meeting—October 15–19

The 42nd Annual Meeting of the Environmental Mutagen Society (EMS) will be held October 15–19 at the Hilton Montréal Boneventure, Montréal, Canada. The theme of the 42nd EMS Annual Meeting is “Environmental Impacts on the Genome and Epigenome: Mechanisms and Risks.” The goals of this meeting are to (i) build on our past contributions to the field of environmental and molecular mutagenesis and DNA repair and more fully understand the role of epigenetics in these basic mechanisms, (ii) integrate applied genetic toxicology with basic research in DNA damage and repair, toxicogenomics, and epigenetics, (iii) determine how this intermingled information can be best used to direct translational human epidemiological studies, (iv) have these data serve as a foundation for human risk assessment for disease and disease prevention, and finally (v) aid in the support of knowledge-based regulation to protect the public health and the environment. For more information visit the EMS Annual Meeting Web site.

21st ISES Annual Meeting—October 23–27

The 2011 meeting of the International Society of Exposure Science (ISES), entitled “Advancing Exposure Science for Environmental Health,” will be held October 23–27, 2011, at the Baltimore Waterfront Marriott Hotel, Baltimore, Maryland. This ISES meeting will gather scientists from all over the globe to share current research activities and explore emerging trends in exposure science and environmental health. This meeting brings together scientists, engineers, and policy makers from a variety of disciplines to highlight significant achievements and awareness of the role of exposure science in human health. For more information and to register, go to the ISES Annual Meeting Web site.

27th International Neurotoxicology Conference—October 31–November 2

The 27th International Neurotoxicology Conference (NEUROTOX 27) will be held October 31–November 2, 2011, at the Sheraton Imperial Hotel and Conference Center, Research Triangle Park, North Carolina. A series of tutorial talks by world experts will kick off the meeting on Sunday, October 30, 2011. This workshop will focus on endocrine interactions, sex differences, and inflammation as common mechanisms by which environmental factors confer susceptibility to complex neurodevelopmental disorders and synaptic plasticity as a common target. The goal of this session is to provide background and context for the remaining sessions. Presenters will focus on what is currently known about the role of the endocrine and immune systems in neurodevelopment and mechanisms of endocrine disruption. Papers, discussion, and Q&A summaries, and recommendations rapidly will be published on-line and in NeuroToxicology. For additional information, please visit the Neurotoxicology Web site.

Save the Date

PPTOX III—Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms—May 14–16, 2012

The Prenatal Programming and Toxicology (PPTOX III) international conference will be held May 14–16, 2012, in Paris, France. This Contemporary Concepts in Toxicology Meeting, hosted by SOT, also is sponsored by anses (agence nationale de sécurité, alimentation, environment, travail), NIEHS, and NCTR. PPTOX III will focus on the role of environmental exposures and nutrients during development on subsequent diseases/dysfunctions later in life. The goal of the conference is to examine the animal and human data supporting this hypothesis (developmental basis of disease) by disease, organ system, and mechanism in order to review the current state of the literature and to identify mechanisms for the effects as well as to identify research gaps and challenges and to integrate the basic and applied science.

During the meeting the following topics will be discussed: new epidemiological and toxicological evidence for the contribution of developmental exposure to adult disease; predictive value of animal and alternative models; the essential contribution of epigenetics to programming; the effect of chemical or physical insults as well as nutritional imbalance on stem cells, and the long path from discovery to regulation. In additional to the session presentations, oral presentations will be selected from the abstract submissions. The early abstract submission deadline is December 15, 2011, and standard abstract submission deadline is March 22, 2012. To learn more, to register, and to apply for student travel awards, please visit the PPTOX III Web site.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert April 2011

April 10, 2011

Our spectacular 2011 50th Anniversary Annual Meeting is now a memory that we will cherish for years to come. A record-shattering 8,100 attendees from around the globe, including 21% international participants, were engaged in an impressive program of highly informative symposia, workshops, roundtables, and other special sessions.

Proposal submissions for the 2012 Annual Meeting, March 11–15, 2012, in San Francisco, California, are well underway. (The proposal submission site is open until April 30 and is accessible using the Abstract Submission Web site). The Scientific Program Committee is encouraging you to consider contributing proposals that align to the themes below, although all topics relevant to toxicology will be considered on their merits.

  • Aberrant Gene Expression in Toxicity and Disease—Epigenetics and MicroRNAs
  • Characterizing Toxic Modes of Action and Pathways to Toxicity
  • Influence of Global Climate Change on Environmental Health Issues
  • Clinical Toxicology from Bedside to the Bench and Back
  • Regulatory Science: Bridging the Gap between Discovery and Product Availability

In addition, SOT is committed to strengthening partnerships with other scientific and health-based organizations and sponsors meetings that may be of interest to you. Please see the information below or contact the organizers directly if you wish to participate.

Michael P. Holsapple
SOT President

SOT-Sponsored Meetings

Beyond Science and Decisions: ARA Workshop III—May 4–6

The Alliance for Risk Assessment (ARA) has been holding a series of public workshops to continue discussion on dose-response assessment issues set forth by the NAS’s 2008 report: “Science and Decisions: Advancing Risk Assessment” (“The Silver Book”). The third of these workshops, “Beyond Science and Decisions: From Issue Identification to Dose-Response Assessment,” will be held May 4–6, 2011, at Noblis, Inc., Falls Church, Virginia. ARA is a broad-based non-profit, government and NGO coalition. The ultimate goal is consensus among participants on guidance highlighting key considerations for applying a variety of dose-response techniques to different risk assessment settings, as characterized in early problem formulation or issue identification. These workshops are highly interactive, with participation from federal, state, industry, NGO, academia, and research institutes. For additional information, please visit the workshop’s ARA Web site.

ACT Toxicology for Industrial and Regulatory Scientists Course—May 16–20

The American College of Toxicology (ACT) is holding a course to provide basic training in toxicology for individuals who are starting a career in toxicology or as a refresher to those who have been in the industry or regulatory environment. The course will be held from May 16–20 at Noblis Inc., Falls Church, Virginia. Attendees will obtain an overall understanding of the principles of nonclinical safety evaluation with emphasis on the practical application of these principles and interpretation of nonclinical safety data. Topics will include principles and application of toxicology, PK/ADME, safety pharmacology, general and organ system toxicology, clinical pathology, pathology, genetic toxicology, carcinogenicity, reproductive toxicology, immunotoxicology, safety evaluation of biotechnology-derived products, clinical toxicology, risk assessment/evaluation, and regulatory toxicology. A workshop of nonclinical assessment and development strategy of a drug taught by distinguished experts in the field of toxicology is also included. For more information and registration forms see the ACT Web site.

CSTS, SETAC-Africa, and NEF Meeting, Cameroon—
May 31–June 3

The Cameroon Society for Toxicological Sciences (CSTS), in conjunction with Society for Environmental Toxicology and Chemistry (SETAC-Africa), and Africa Educational Initiative (NEF), is holding a joint toxicology conference at the University of Buea from May 31–June 3, 2011. The theme of the conference is “Searching for African Solutions to Human and Environmental Toxicological Challenges.” The joint SOT-Sponsored toxicology conference is organized to bring together stakeholders involved in research, production, utilization, release, management, and regulation of toxic chemicals. The upcoming conference will offer a two-day general toxicology course and workshops that will introduce participants to toxicology as a science; help participants who are interested in toxicology as a future career to make the right choice of disciplines; and broaden the knowledge base of researchers in the areas of toxicology. The conference proceedings will cover most areas in Toxicology with participants from 26 different countries. For details visit the CSTS Web site.

Society of Toxicologic Pathology Annual Meeting—June 19–23

The Society of Toxicologic Pathology (STP) Annual Meeting will be held from June 19–23, 2011, at the Hyatt Regency, Denver, Colorado. STP will host a symposium on the fundamentals and recent innovations in the field of toxicologic pathology and the immune system. The focus of this international meeting is to correlate advances in the morphologic evaluation and interpretation of immunopathology findings with functional, cellular, and molecular knowledge in a series of plenary and poster sessions. The meeting also will provide a unique forum to review the progress in the application of best practices for routine and specialized pathology evaluations of the immune system across the pharmaceutical, chemical, and academic worlds of pathology. For more information, please visit the STP Annual Meeting Web site.

51st Annual Meeting of Teratology Society—Late Breaking Abstract Deadline June 1

The 51st Annual Meeting of the Teratology Society will be held June 25–29, 2011, in Coronado, California. The theme of the meeting is “Translational Research in Birth Defects: From Mechanism to Epidemiology.” This meeting emphasizes translational research in the study of birth defects. There will be special emphasis on the risks of chemicals in our environment, environmental influences on attention deficit hyperactivity disorder, and the impact of iodine on thyroid health and function. For general information, visit the Teratology Society Meeting Web site and to submit late-breaking abstracts visit the Abstract Submission Web page.

Neurobehavioral Teratology Society 35th Annual Meeting—
June 25–29

The 35th Annual Meeting of the Neurobehavioral Teratology Society (NBTS) will be held June 25–29, 2011, at the Loews Coronado Bay Resort, in Coronado (San Diego), California, in conjunction with the 51st Annual Meeting of the Teratology Society and the 24th Annual Meeting of the Organization of Teratology Information Specialists (OTIS). This meeting provides a significant opportunity for research scientists, health professionals, and risk assessors to present and discuss cutting-edge information on the evaluation and interpretation of toxicological effects on the developing nervous system that are associated with exposures to environmental toxicants and other chemicals. For additional information, please visit the NBTS Conference Web site.

GRC Cellular and Molecular Mechanisms of Toxicity, August 7–12

The 2011 Gordon Research Conference (GRC), “Cellular & Molecular Mechanisms of Toxicity: Understanding Innovative Mechanistic Toxicology in the Post-Genomic Era,” August 7–12, 2011, Proctor Academy, New Hampshire, will feature cutting-edge mechanistic toxicological research relevant to environmental, pharmaceutical, and industrial sciences. The conference will bring together outstanding investigators at the forefront of their field in a collegial atmosphere, with programmed discussions as well as opportunities for informal gatherings in the afternoons and evening. This forum for the exchange of ideas in the field of toxicological knowledge and its enabling technologies will include the latest advancements in cellular and molecular mechanisms that underpin toxicology, environmentally-linked human disease, cutting-edge advances in exposure assessment, and evidence-based decision making. Applications are on-line and due by June 30, 2011, to be considered for an oral presentation and by July 10, 2011, for conference attendance. For complete conference information, visit the GRC Web site.

IDARS Third Annual Meeting—August 23–26

The Third Annual International Drug Abuse Research Society (IDARS) Meeting, in conjunction with the International Society for Neurochemistry and the European Society for Neurochemistry, will be held August 23–26, 2011, Istanbul, Turkey. This meeting will bring together basic scientists and clinical investigators from the international community to provide in-depth understanding and current knowledge concerning new conceptual insights into the central nervous system acting drugs and drugs of abuse and treatment of drug addiction. The aim of the meeting is to advance science and better understanding of the underlying toxicology of these drugs of abuse. Participation from 15 different countries is anticipated. The overall format of the meeting will result in a productive exchange of information not only for neuroscientists but also investigators from other disciplines. For more information, visit the IDARS Web site.

EMS 42nd Annual Meeting—Early Review Abstract Submission June 1

The 42nd Annual Meeting of the Environmental Mutagen Society (EMS) will be held October 15–19, 2011, Hilton Montréal Bonaventure, Montréal, Québec. The theme of this meeting is “Environmental Impacts on the Genome and Epigenome: Mechanisms and Risk.” The Society, and the Annual Meeting, are unique in bringing together scientists who carry out basic research with those involved in risk estimation and regulatory concerns related to the consequences of exposure to environmental and pharmaceutical agents. The result is a dynamic meeting that is sufficiently large enough to cover a broad range of contemporary topics yet focused and small enough to facilitate interactions between students and renowned scientists in academia, government, and industry. For general information, visit the EMS Meeting Web site and to submit an early review abstract view the on-line abstract instructions.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert February 2011

January 30, 2011

50th Anniversary SOT Annual Meeting—A Landmark Event

The Annual Meeting is six weeks from now and already over 4,900 scientists have registered to attend. Like me, I am sure you are including many of the special activities described on the 50th Anniversary Web site in your Annual Meeting Itinerary. Highlights of the March 6–11, 2011, SOT Annual Meeting in Washington, D.C. include:

  • Over 2,800 presentations, including featured lectures plus 241 late-breaking and grace period abstracts. This number exceeds all past Annual Meetings
  • For the first time in its 50-year history, SOT will feature four plenary speakers
  • Six “Meet the Directors Series” of lectures will update attendees on key federal initiatives underway to help advance the science of toxicology
  • Historical Highlight sessions feature an overview of the “The Pill” and its impact on Society and a 50-Year Retrospective on the Evolution of the Science of Toxicology

We look forward to seeing you at this special Annual Meeting that will provide you with wonderful memories for years to come.

Jon C. Cook
2010–2011 Vice President

SOT Non-SOT Sponsored Meetings

SOT is committed to strengthening partnerships with scientific and health-based organizations and has sponsored meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

ToxForum Winter Meeting Focuses on U.S. FDA Revisions to GLP Regulations—February 1–3, 2011

The 36th Annual Winter Meeting of the Toxicology Forum will be held February 1–3, 2011, Washington, D.C. Among the topics to be addressed is the U.S. Food and Drug Administration’s (U.S. FDA) proposed revisions to its Good Laboratory Practices (GLP) Regulations, the first since 1978. The proposed rulemaking on 21 CFR Part 58 will constitute “the law” for GLP regulations. Commentary period for this proposal is scheduled to close February 22, 2011, and a late-breaking update, “U.S. FDA Calls for Comments to Amend its GLP Regulations” will be presented. For additional information, visit the ToxForum Web site.

Evidence-Based Toxicology Collaboration Kickoff—March 10 Satellite Meeting

In conjunction with the SOT Annual Meeting, the Johns Hopkins Center for Alternatives in Animal Testing (CAAT) will convene an Evidence-Based Toxicology (EBT) Collaboration Kick-Off Meeting, Thursday, March 10, from 12:00 NOON–3:00 PM in Room 206 of the Walter E. Washington Convention Center. At the workshop, speakers will present the concept of EBT as it pertains to decision-making about the utility of new toxicity tests and their implementation into the risk assessment process. The anticipated promise of EBT is to provide a quality, science-driven approach to assessing the effects of drugs and chemicals on human health and the environment and provides principles of how to incorporate published information into the decision-making process. For further information and to register for the workshop, visit the CAAT Web site.

Environmental Epigenomics and Disease Susceptibility—March 27–April 1, 2011

A Keystone Symposia on Molecular and Cellular Biology, Environmental Epigenomics and Disease Susceptibility, will be held March 27–April 1, 2011, at the Grove Park Inn, Ashville, North Carolina.

The four-day Keystone Symposia conference will include plenary sessions and talks designed to elicit a greater understanding of the effects of pre- and postnatal exposure to environmental toxins on development of various childhood and adult-onset disorders ranging from neurological conditions to cancer and cardiovascular/metabolic disease. The meeting will bring together diverse scientists including toxicologists, developmental biologists, evolutionary biologists, and clinical investigators. For further information, please visit the Keystone Symposia Web site.

IV Latin America Risk Assessment Workshop—April 3–10, 2011

The IV Latin America Risk Assessment (IV LARAW) Workshop will be held April 3–10, 2011, at the Grande Hotel São Pedro, Águas de São Pedro, São Paulo, Brazil. Sponsored by the Brazilian Society of Toxicology and the International Union of Toxicology (IUTOX), the workshop is based on the previous 20 years of experience of the Risk Assessment Summer School (RASS) sponsored by IUTOX. The objectives of the workshop are to offer young Latin American toxicologists unique opportunities (1) to broaden their knowledge and experience in the field of chemical risk assessment and (2) to better understand the data evaluation process. For more information, please view the IV LARAW Flyer.

Society of Toxicologic Pathology Annual Meeting—Abstract Deadline March 1

The Society of Toxicologic Pathology (STP) Annual Meeting will be held from June 19–23, 2011, at the Hyatt Regency, Denver, Colorado. STP will host a symposium on the fundamentals and recent innovations in the field of toxicologic pathology and the immune system. The focus of this international meeting is to correlate advances in the morphologic evaluation and interpretation of immunopathology findings with functional, cellular, and molecular knowledge in a series of plenary and poster sessions. The meeting will also provide a unique forum to review the progress in the application of best practices for routine and specialized pathology evaluations of the immune system across the pharmaceutical, chemical, and academic worlds of pathology. The abstract deadline is March 1, 2011. For more information, please visit STP Annual Meeting Web site.

Teratology Society Holds 51st Annual Meeting—Abstract Deadline February 14

The 51st Annual Meeting of the Teratology Society will be held June 25–29, 2011, in Coronado, California. The theme of the meeting is “Translational Research in Birth Defects: From Mechanism to Epidemiology.” The program includes a variety of scientific sessions on topics ranging from stem cells to zebrafish embryology, epidemiology, chemical safety assessment, and nutrition. The members of this society include clinicians, scientists, and science policy regulators, from academia, industrial, and government sectors. Researchers who attend this meeting are focused on the causes, manifestations, intervention, and prevention of birth defects. For more information, visit the Teratology Annual Meeting Web site.

News of Note

CSR’s Peer Review Notes Includes Updates on Study Sections

The January 2011 issue of Peer Review notes, published by the Center for Scientific Review (CSR), includes two articles that may be of particular interest to SOT members.

New Tool to Assess the Fields of Science Covered by CSR Study Sections

Visualize a new way to see the challenges faced by our study sections—Mapping publication data revealed differences in the extent of interdisciplinarity across study sections. CSI Peer Review Notes, January 2011.

Realignment and Reorganization of CSR Study Sections

Discover what CSR is doing to keep study sections up to date and transparent about significant changes, including the launch of a new Web site. CSI Peer Review Notes, January 2011.

CSR publishes Peer Review Notes to inform reviewers, NIH staff, and other interested constituents about news related to NIH grant application review policies, procedures, and plans. Comments may be sent to Don Luckett, Communications Director.

Upcoming Meetings

Save the Date: August 7–12, 2011

The 2011 Gordon Research Conference (GRC), “Cellular and Molecular Mechanisms of Toxicity,” will feature cutting-edge mechanistic toxicological research relevant to environmental, pharmaceutical, and industrial sciences. With topics such as inflammation, repair/adaptation, clock genes, epigenomics, hepatotoxicity, neuroinflammation, individual susceptibility, and predictive toxicology, the conference will bring together outstanding investigators at the forefront of their field. To apply for this meeting, please visit the GRC Web site. A list of preliminary session topics and speakers is displayed on the conference Web site. The detailed program is currently being developed by the Conference Chair and will be available by April 7, 2011. Please check back for updates by visiting the conference Web site.

For more information on future meetings, please visit the SOT Calendar of Events.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert—SOT Sponsored Meetings

October 5, 2010

Dear SOT Members:

Plans are underway for an exciting 50th Anniversary Society of Toxicology Annual Meeting. A record number of scientific abstracts—almost 2500—were submitted—a preview of the comprehensive, cutting-edge science that will be presented during this March 6–10, 2011, Annual Meeting in Washington, D.C. For an overview of upcoming deadlines and additional information, visit the 2011 Annual Meeting and ToxExpo™ Web site and the 50th Anniversary Celebration Web site.

In the meantime, there are a number of SOT Regional Chapter Meetings and SOT Sponsored Meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Northland Chapter Fall Meeting and Real-Time Web Cast—October 7
Toxicology Testing: Alternatives for the 21st Century, Minnesota Department of Health, St. Paul, Minnesota. An audio recording of this meeting will be posted on-line. For more information, visit the NLSOT Web site.

North Carolina Chapter Fall Meeting—October 7
Bioengineered Cellular and Animal Models for Toxicology, NIEHS Campus, Durham, North Carolina. For more information, visit the NCSOT Web site.

Southern California Regional Chapter Fall Meeting—October 9
Advancing the Science of Carcinogenic Risk Assessment, UCLA—Conference Facility, Lake Arrowhead, California. For more information, visit the SCSOT Web site.

Southeastern Regional Chapter Meeting—October 11–12
Plenary Speakers: Cheryl Lyn Walker, Randy L. Jirtle, Michael Aschner, and Harvey Clewell, Georgia Center for Continuing Education; Location: Athens, Georgia. For more information, visit the SESOT Web site.

Gulf Coast Chapter Meeting—October 14–15
Fetal Basis of Disease, Children’s Nutrition Research Center at Baylor College of Medicine Meeting, Houston, Texas. For more information, visit the GCSOT Web site.

Pacific Northwest Chapter Meeting—October 14–16
Integrative Toxicity Test Methods to Improve Hazard Identification, Oregon State University, Corvallis, Oregon. For more information, visit the PANWAT Web site.

National Capital Area Chapter Fall Symposium—October 28
Food Safety—From Farm to Table, University of Maryland, College Park, For more information, visit the NCAC Web site.

Michigan Regional Chapter, Fall 2010 Meeting—October 29
The Developmental Origins of Disease—Emerging Mechanistic Knowledge, Hanna Center, East Lansing, Michigan. For more information, visit the MISOT Web site.

Mid-Atlantic Chapter Fall 2010 Symposium—November 2
Epigenetics: Toxic Responses and Disease, Rutgers EcoComplex, Bordentown, New Jersey. For more information, visit the MASOT Web site.

SOT Sponsored Meetings

Environmental Mutagen Society 41st Annual Meeting—October 23–27
The 41st Annual Meeting of the Environmental Mutagen Society (EMS), “Complex Systems in Biology and Risk Assessment,” will be held October 23–27, 2010, at the Omni Fort Worth Hotel. The meeting provides a broad scientific forum for basic and applied researchers, students and teachers to review the latest information linking environmental conditions to adverse health outcomes. Topics include Genotoxicity of Nanomaterials, Replication Stress, Is Tobacco Smoke a Germ-Cell Mutagen, Inflammation: From Molecules to Human Populations, Cognitive Consequences of Fetal and Early Postnatal Exposure to Environmental Contaminants, and Genotoxic Consequences of the BP Oil Spill and Clean-Up. Special lectures on Copy Number Variation, Epigenetics and Cancer, Genetic Toxicology, Childhood Cancer Causes, and Women in Science are planned. Of note is a special career development workshop with representatives from both traditional and non-traditional career paths providing career advice and networking opportunities for students and postdocs. This is a meeting not to be missed. For additional information, visit the EMS 2010 Annual Meeting Web site.

Reproductive and Developmental Toxicology for Industrial and Regulatory Scientists Course—October 25–28
The Teratology Society is holding a course to provide basic training in reproductive and developmental toxicology for individuals who are starting a career in reproductive toxicology or as a refresher to those who have been in the industry or regulatory environment. The course will be held from October 25–28, 2010, at Noblis Inc., Falls Church, Virginia. Attendees will obtain an overall understanding of the basic biology in reproduction and development, principles of various testing approaches for reproductive and developmental toxicology, with strong emphasis on the practical application of these principles and interpretation of developmental and reproductive toxicology data. The course will be taught by distinguished experts in the field of developmental and reproductive toxicology. For more information and registration forms visit the Teratology Web site.

Accelerating Implementation of NRC Vision for Toxicity-Testing in the 21st Century—November 9–10
The Human Toxicology Project Consortium is convening a workshop on “Accelerating Implementation of the NRC Vision for Toxicity Testing in the 21st Century,” November 9–10, 2010, at Kellogg Conference Center, Gallaudet University, Washington, D.C. This workshop will evaluate progress to date and identify the highest priority needs to accelerate implementation of the NRC recommendations. It will also underscore the need for a concerted effort…a “Human Toxicology Project”…on the order of large-scale biology projects such as the Human Genome Project, in order to ensure timely success. The workshop will be supplemented with a summary of the proceedings published in the scientific literature. For additional information, visit the workshop’s Web site.

MSU and NIEHS Health Consequences from Xenobiotic—Gut Microbiome—Host Interactions Workshop—November 17–18
Michigan State University (MSU) in cooperation with the National Institute for Environmental Health Sciences (NIEHS) Superfund Research Program, is organizing a workshop, entitled “Health Consequences from Xenobiotic—Gut Microbiome—Host Interactions” to be held November 17–18 on the NIEHS campus in Research Triangle Park, North Carolina. The overarching goal of the workshop is to discuss an emerging area in toxicology and environmental health sciences that is concerned with interactions between gut-associated microbes (i.e., gut microbiota, intestinal microbiome) and environmental contaminants and the untoward consequences of these interactions on human health. This conference will bring together biomedical scientists focused on human health effects of environmental chemicals and microbiologists with expertise in the intestinal microbiome. The workshop will explore the role of interactions between environmentally relevant xenobiotic agents with gut-associated microbes that either increase or decrease the risk or severity of various human diseases. For additional information, visit the workshop’s Web site.

Upcoming Conference of Note

Save the Date: August 7–12, 2011
The 2011 Gordon Research Conference (GRC), “Cellular and Molecular Mechanisms of Toxicity,” will feature cutting-edge mechanistic toxicological research relevant to environmental, pharmaceutical, and industrial sciences. With topics such as inflammation, repair/adaptation, clock genes, epigenomics, hepatotoxicity, neuroinflammation, individual susceptibility, and predictive toxicology, the conference will bring together outstanding investigators at the forefront of their field. To apply for this meeting, please visit the GRC Web site.

A list of preliminary session topics and speakers is displayed on the conference Web site. The detailed program is currently being developed by the Conference Chair and will be available by April 7, 2011. Please check back for updates by visiting the conference Web site.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one- to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert—September 2010 Issue

September 8, 2010

Dear SOT Members:

The next 50th Anniversary 2011 SOT Annual Meeting deadline is fast approaching. The abstract submission site is now open to accept abstracts for poster and platform presentations, with the deadline of October 3, 2010, at 11:59 PM EDT. In addition, we recently announced that key members of federal agencies have confirmed to deliver keynote plenary lectures: Dr. Francis Collins (Director of NIH), Dr. Margaret Hamburg (U.S. FDA Commissioner), and Dr. Lisa Jackson (U.S. EPA Administrator). The fourth plenary lecturer will be featured at the annual MRC Lecture. In addition, we have expanded the Meet the Directors series as requested by attendees from three to five guest lecturers. Be sure to reserve Tuesday night for the special 50th Anniversary Celebration to mark this landmark event. For more information on this sensational celebration, visit the 50th Anniversary Web site.

SOT is committed to strengthening partnerships with scientific and health-based organizations and has sponsored meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Michael P. Holsapple, SOT President

Genetic Toxicology Association 2010 Meeting—September 15–16

The 2010 Genetic Toxicology Association (GTA) Meeting, entitled “Genetic Toxicology in the 21st Century: The Scientific Basis for New Technologies and Regulatory Guidance,” will be held September 15–16 on the campus of the University of Delaware in Newark, Delaware. The meeting will offer a comprehensive program focusing on important emerging issues in genetic toxicology. Symposia and interactive workshop topics include: Screening Strategies and Methods to Predict Genotoxicity, Cellular Response to DNA Damage, Integration of Single or Multiple Genotoxicity Endpoints into In Vivo Studies, In Silico Analysis: Theory and Applications, New Technologies, and Update on Actual and Proposed Regulatory Changes. Presentations will be given by leading scientists representing the cosmetic, pharmaceutical, and chemical industries, as well as U.S. government agencies, contract research organizations, and academia. In addition, the meeting will provide several great opportunities for networking, including a student networking breakfast, a poster session, and a dinner. For further information, please visit the GTA Web site.

Tenth International Conference on Neuroprotective Agents—September 19–22

The Tenth International Conference on Neuroprotective Agents (ICNA) will be held September 19–22, 2010, at the Asilomar Conference Grounds in Pacific Grove (Monterey/Carmel Region), California. Virtually all attendees are presenters (platform or poster); the multidisciplinary background of the participants and the meeting’s structure (all sessions, including the poster session, are attended by all participants; meals and social events are also group functions) fosters in-depth, real-time discussion and debate. The ICNA brings together researchers involved in (1) conditions toxic to the nervous system (e.g., heat, diabetes, drugs (therapeutic and illicit), alcohol, anesthetic agents, and stroke); (2) neurodegenerative processes ‘toxic’ to the nervous system (e.g., Parkinson’s disease, Alzheimer’s disease); (3) molecular and nanotechnology techniques for understanding nervous system disorders, nervous system repair mechanisms, and neurotoxicity issues; (4) the fields of personalized, predictive, and preventive medicine as they relate to neuroprotection. For more information, visit the INCA Web site.

Safety Pharmacology Society—10th Anniversary Annual Meeting—September 20–23

The Safety Pharmacology Society (SPS) Annual Meeting will be held September 20–23 in Boston, Massachusetts. This is the most focused scientific meeting targeting the role of safety pharmacology in drug development. Presentations cover a spectrum from theory to practical experience and specific case studies, and the meeting is regarded as one of the best forums for international “best practice sharing” within the pharmaceutical industry, with contract laboratories, and with regulators. In addition, the SPS Annual Meeting offers a comprehensive program of continuing education courses to accommodate both newcomers to the field as well as those with experience in advanced courses. This meeting is recognized as a forum for highlighting new areas in which safety pharmacology is thought to have an impact in the future to improve drug safety. For further information, please visit the SPS 2010 Annual Meeting Web Site.

Beyond Science and Decisions—ARA Workshop II—October 11–13

The Alliance for Risk Assessment (ARA) has been holding a series of public workshops to continue discussion on dose-response assessment issues set forth by the NAS’s 2008 document: Science and Decisions: Advancement of Risk Assessment (the silver book). The second of these workshops, Beyond Science and Decisions: From Issue Identification to Dose-Response Assessment, will be held October 11–13, 2010, Double Tree Hilton, Crystal City, Virginia. This includes a Joint Meeting with the U.S. Federal-State Toxicology and Risk Analysis Committee (FSTRAC). The purpose of the workshop is to advance the recommendations in the NAS (2008) report concerning issue identification (problem formulation) and dose-response analysis, through review of illustrative case studies for further development of a methods text. This series of workshops will be highly interactive, with participation from federal, state, industry, NGO, academia, and research institutes. For additional information, please visit the workshop’s Web site.

Environmental Mutagen Society—41st Annual Meeting—Late Breaking Abstract Deadline October 4

The 41st Annual Meeting of the Environmental Mutagen Society (EMS), “Complex Systems in Biology and Risk Assessment,” will be held October 23–27, 2010, at the Omni Fort Worth Hotel. The meeting provides a broad scientific forum for basic and applied researchers, students and teachers to review the latest information linking environmental conditions to adverse health outcomes. Topics include Genotoxicity of Nanomaterials, Replication Stress, Is Tobacco Smoke a Germ-Cell Mutagen, Inflammation: From Molecules to Human Populations, Cognitive Consequences of Fetal and Early Postnatal Exposure to Environmental Contaminants, and Genotoxic Consequences of the BP Oil Spill and Clean-Up. Special lectures on Copy Number Variation, Epigenetics and Cancer, Genetic Toxicology, Childhood Cancer Causes, and Women in Science are planned. Of note is a special career development workshop with representatives from both traditional and non-traditional career paths providing career advice and networking opportunities for students and postdocs. This is a meeting not to be missed. Late breaking abstracts can be submitted on-line. For additional information, visit the EMS 2010 Annual Meeting Web site.

Accelerating Implementation of NRC Vision for Toxicity-Testing in the 21st Century—November 9–10

The Human Toxicology Project Consortium is convening a workshop on “Accelerating Implementation of the NRC Vision for Toxicity Testing in the 21st Century,” November 9–10, 2010, at Kellogg Conference Center, Gallaudet University, Washington, D.C. This workshop will evaluate progress to date and identify the highest priority needs to accelerate implementation of the NRC recommendations. It will also underscore the need for a concerted effort…a “Human Toxicology Project”…on the order of large-scale biology projects such as the Human Genome Project, in order to ensure timely success. The workshop will be supplemented with a summary of the proceedings published in the scientific literature. For additional information, visit the workshop’s Web site.

MSU and NIEHS Health Consequences from Xenobiotic—Gut Microbiome—Host Interactions Workshop—November 17–18, 2010

Michigan State University (MSU) in cooperation with the National Institute for Environmental Health Sciences (NIEHS) Superfund Research Program, is organizing a workshop, entitled “Health Consequences from Xenobiotic—Gut Microbiome—Host Interactions” to be held November 17–18 on the NIEHS campus in Research Triangle Park, North Carolina. The overarching goal of the workshop is to discuss an emerging area in toxicology and environmental health sciences that is concerned with interactions between gut-associated microbes (i.e., gut microbiota, intestinal microbiome) and environmental contaminants and the untoward consequences of these interactions on human health. This conference will bring together biomedical scientists focused on human health effects of environmental chemicals and microbiologists with expertise in the intestinal microbiome. The workshop will explore the role of interactions between environmentally relevant xenobiotic agents with gut-associated microbes that either increase or decrease the risk or severity of various human diseases. For additional information, visit the workshop Web site.

Save the Date: August 7–12, 2011

Gordon Research Conference—Cellular & Molecular Mechanisms of Toxicity: Understanding Innovative Mechanistic Toxicology in the Post-Genomic Era

The 2011 Gordon Research Conference (GRC), “Cellular and Molecular Mechanisms of Toxicity,” will be held August 7–12, 2011, Proctor Academy, New Hampshire. The conference will feature cutting-edge mechanistic toxicological research relevant to environmental, pharmaceutical, and industrial sciences. With topics such as inflammation, repair/adaptation, clock genes, epigenomics, hepatotoxicity, neuroinflammation, individual susceptibility, and predictive toxicology, the conference will bring together outstanding investigators at the forefront of their field. A list of preliminary session topics and speakers is displayed on the conference Web site. To apply for this meeting, please visit the GRC Web site.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one-to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT Science News Alert—June 2010 Issue

June 24, 2010

Dear SOT Members:

I am pleased to report that the Society of Toxicology has received a record number—202—proposal submissions for the SOT 50th Annual Meeting, and the Scientific Program Committee has responded by increasing the number of sessions that will be offered in 2011. SOT’s 50th Anniversary Annual Meeting and ToxExpo™ will be held March 6–10, 2011, at the Walter E. Washington Convention Center, Washington, D.C. Special events are planned, including a March 8 celebration that will capture the sights and sounds of 1961, the year SOT was established. You are encouraged to visit and return to the 50th Anniversary Web site often to remain up-to-date on the latest news about the Society’s Annual Meeting activities and events being rolled out to highlight this special landmark. To date, the Society has confirmed plenary speakers Francis Collins, Director of the National Institutes of Health, and Margaret Hamburg, U.S. Food and Drug Administration Commissioner. SOT is committed to strengthening partnerships with scientific and health-based organizations and has sponsored meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Michael P. Holsapple, SOT President


21st Century Validation Strategies for 21st Century Tools—
July 13–14, 2010

A workshop on “21st Century Validation Strategies for 21st Century Tools” will be held July 13–14, 2010, at the Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland. Chemical safety testing has come into the limelight. The emerging discussion of the TSCA reauthorization in the U.S. and the start of REACH registration in the EU leave no doubt that a new approach to toxicology is called for. That new approach was neatly outlined in the 2007 NRC report Toxicity Testing in the 21st Century: A Vision and a Strategy. This program will address the following topics: Integrated Testing Strategies, Modern Technology Integration, Evidence-based Toxicology, and Endocrine Disruption as a possible pilot area. For additional information, contact Marilyn Principe via e-mail or visit the CAAT Workshop Web site.

8th International Symposium on Biological Reactive Intermediates—
July 15–18, 2010

The 8th International Symposium on Biological Reactive Intermediates (BRIVIII), “BRI’s: Impact and Human Relevance,” is being held in Barcelona, Spain, July 15–18, 2010, hosted by the IMIM-Hospital del Mar and Parc de Recerca Biomedica Barcelona (PRBB), Spain. The conference is a Satellite Meeting of the XII International Conference of Toxicology, also being hosted in Barcelona the following week (July 19–23). The strategy for BRIVIII will be the integration of data on biological reactive intermediates from across disciplines (chemistry, analytical chemistry, biochemistry, pharmacology, toxicology, epidemiology, etc.) culminating in examples of human exposure to BRIs resulting in disease. For complete conference information, including a description of the scientific program, visit the BRIVIII Web site.

4th Biennial ACMT Medical Toxicology Board Review Course—
September 11–13, 2010

The American College of Medical Toxicology (ACMT), the only professional association that focuses solely on medical toxicology, will offer its 4th Biennial Medical Toxicology Board Review course in Cincinnati, Ohio, September 11–13, 2010. This course is an excellent review of toxicological topics for anyone seeking an update. Attendees can strengthen their practical knowledge in key subjects by attending the “stimuli” room with clinical images and case-based modules. The setting provides the added benefit of an intensive learning environment that helps prepare you for board subspecialty exams. Download the course brochure for registration and additional course information.

Dioxin 2010—September 12–17, 2010

The International Symposium on Halogenated Persistent Organic Pollutants (POPs)—Dioxin 2010, will be held from September 12–17, 2010, San Antonio, Texas. The symposium will return to the United States after six years around the globe. Dioxin 2010 will offer a diverse scientific program, encompassing many of the traditional topics and also addressing new and emerging areas. The technical program will have a strong focus on toxicology and health, as well policy issues associated with halogenated persistent organic pollutants. For additional information, contact Daniele Staskal via e-mail and visit the conference Web site.

International Workshop on Alternative Methods for Vaccine Potency and Safety Testing: State of the Science and Future Directions—
September 14–16, 2010

Abstract Deadline: July 29 The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces an “International Workshop on Alternative Methods to Reduce, Refine, and Replace the Use of Animals in Vaccine Potency and Safety Testing: State of the Science and Future Directions.” Organized by NICEATM and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) in partnership with the European Centre for the Validation of Alternative Methods (ECVAM), Japanese Center for the Validation of Alternative Methods (Java), Health Canada, and co-sponsored by the SOT, this workshop will be held at the William H. Natcher Conference Center on the campus of the National Institutes of Health, Bethesda, Maryland. Registration information, tentative agenda, and additional meeting information are available on the NICEATM-ICCVAM Workshop Web site. Information is also available upon request from NICEATM via e-mail or call 919.541.2384.

Tenth International Conference on Neuroprotective Agents—
September 19–22, 2010

Abstract Deadline: July 1

The Tenth International Conference on Neuroprotective Agents will be held September 19–22, 2010, at the Asilomar Conference Grounds in Pacific Grove (Monterey/Carmel Region), California. The abstract submission deadline for platform and poster presentations is July 1, 2010. This conference brings together clinical and basic science researchers from various countries and various disciplines related to neuroprotection in an intellectually stimulating and socially relaxing environment. Virtually all attendees are presenters (platform or poster); the multidisciplinary background of the participants and the meeting’s structure (all sessions, including the poster session, are attended by all participants; meals and social events are also group functions) fosters in-depth, real-time discussion and debate. For additional, including abstract submission, registration and housing, visit the conference Web site.

2010 In Vitro Alternatives Forum—
October 18–19, 2010

Abstract Deadline: June 30

The In Vitro Alternative Forum will be held October 18–19, 2010, in Old Town Alexandria, Virginia. The emergence of new national and international programs mandating increased toxicological safety testing of products and ingredients is a major driving force for the development of a “new toxicology.” From the REACH program in Europe to the reauthorization of TSCA in the U.S., new legislation is making faster and more reliable testing methods essential. Join us for the 2010 In Vitro Alternatives Forum to learn about upcoming toxicity testing challenges and the current activities designed to meet them. In addition to presentations on diverse in vitro and in silico methodologies, special emphasis will be placed on alternatives to identify skin sensitizers. Visit the Web site to view the program or submit a poster abstract.

TERA’s Dose-Response Boot Camp—
October 18–22, 2010

Toxicology Excellence for Risk Assessment (TERA) is holding a 5-day intensive hands-on training in hazard characterization and dose-response assessment. TERA’s Dose-Response Boot Camp will be held October 18–22, 2010, at the Noblis facility, located at 3150 Fairview Park Drive South in Falls Church, Virginia 22042. Beginners through expert toxicological risk assessors will learn advanced methods, as well as enhance their understanding and skills in the basics. Course lectures will be supplemented with daily hands-on application exercises. Interested individuals should have a basic understanding of Toxicology and interest in developing skills in human health risk assessment. Upon completion of the course, participants will be able to derive and evaluate risk values and supporting documentation for both non-cancer and cancer risk assessments. Five Continuing Maintenance (CM) points will be available from the American Board of Industrial Hygienists (ABIH). For additional information, visit TERA’s Web site.

Reproductive and Developmental Toxicology for Industrial and Regulatory Scientists Course—
October 25–28, 2010

The Teratology Society is holding a course to provide basic training in reproductive and developmental toxicology for individuals who are starting a career in reproductive toxicology or as a refresher to those who have been in the industry or regulatory environment. The course will be held from October 25–28, 2010, at Noblis Inc., Falls Church, Virginia. Attendees will obtain an overall understanding of the basic biology in reproduction and development, principles of various testing approaches for reproductive and developmental toxicology, with strong emphasis on the practical application of these principles and interpretation of developmental and reproductive toxicology data. The course will be taught by distinguished experts in the field of developmental and reproductive toxicology. For more information and registration forms visit the Web site.

Upcoming Conference of Note

Gordon Research Conference, “Cellular and Molecular Mechanisms of Toxicity (CMOT)”, August 7–12, 2011, Proctor Academy, New Hampshire. To apply or for further information, please visit the conference Web site.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Contemporary Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one-to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT May Science News Alert

May 14, 2010

Dear SOT Members:

Plans are underway for the 50th Anniversary SOT Annual Meeting, March 6–10, 2011, in Washington, D.C., and I encourage you to visit the 50th Anniversary Web site for a preview of what is to come as SOT begins “Celebrating 50 Years of Service in Science.” Commemorative Posters, highlighting key events in SOT’s history are available for your viewing now on the 50th Anniversary Web site and many new features will be rolled out over the upcoming months, including an Anniversary Book and Mentor Tree.

SOT is a proud sponsor of the IUTOX 2010 Congress (XII International Congress of Toxicology), and I look forward to seeing you there July 19–23, 2010, in Barcelona, Spain. SOT also is sponsoring upcoming meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Sincerely,

Michael P. Holsapple, SOT President


9th International Skin Carcinogenesis Conference—June 24–27, 2010

The 9th International Skin Carcinogenesis Conference will be held at Pennsylvania State University, University Park, Pennsylvania, June 24–27, 2010. The conference is a biannual meeting that promotes exchange of state-of-the-art ideas from a diverse group of experts from Europe, Asia, and the United States. The focus of the meeting is on the most recent and relevant advances in biological, cellular, and molecular changes that occur during skin tumor development and discussions of how the skin serves as a model system for the development and treatment of other cancers. Sessions will address understanding the genetic factors that can influence skin cancer susceptibility, how alterations in normal cell signaling and proliferation affect the expression of particular genetic alterations, and how intrinsic and extrinsic factors can modify the neoplastic process. For further information on the program and registration, please visit the conference Web site.

Safety Pharmacology Society 10th Annual Meeting—July 5 Abstract Deadline

The Safety Pharmacology Society (SPS) is holding its 10th Annual Meeting from September 20–23 in Boston, Massachusetts. It is the most focused scientific meeting targeting the role of safety pharmacology in drug development. Presentations cover a wide spectrum ranging from theory to practical experience and specific case studies. Moreover, this event is recognized as one of the best forums for international “best practice sharing” within the pharmaceutical industry, with contract laboratories and regulators. A comprehensive program of continuing education courses are offered to accommodate both newcomers to the field as well as those with experience in advanced courses. To submit an abstract, please access the Scientific Abstract Submission Form. For additional information, visit the conference Web site.

Upcoming Conference of Note

Gordon Research Conference, “Cellular and Molecular Mechanisms of Toxicity (CMOT)”, August 7–12, 2011, Proctor Academy, New Hampshire. To apply or for further information, please visit the conference Web site.

SOT sponsors two types of meetings outside of the SOT Annual Meeting: Current Concepts in Toxicology (CCT) and Non-SOT meetings. CCT meetings are one-to two-day focused, open registration, scientific meetings in contemporary and rapidly progressing areas of toxicological sciences. Non-SOT meetings are sponsored by other not-for-profit organizations and SOT will either endorse or provide sponsorship money to toxicology-related meetings.

SOT March Science Alert—SOT Sponsored Meetings

March 23, 2010

Dear SOT Members:

SOT held another successful Annual Meeting with 6,200 attendees convening in Salt Lake City and plans are underway for the 50th Anniversary Annual Meeting, March 6–10, 2011, in Washington, D.C. In the meantime, many of you are preparing to attend the IUTOX 2010 Congress (XII International Congress of Toxicology), July 19–23, 2010, in Barcelona, Spain and I look forward to seeing you. SOT also is sponsoring upcoming meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Sincerely,

Cheryl Lyn Walker, SOT President


ACT Toxicology for Industrial and Regulatory Scientists Course—April 26–30

The American College of Toxicology (ACT) is holding a course to provide basic training in toxicology for individuals who are starting a career in toxicology or as a refresher to those who have been in the industry or regulatory environment. The course will be held from April 26–30 at Noblis Inc., Falls Church, Virginia. Attendees will obtain an overall understanding of the principles of nonclinical safety evaluation with emphasis on the practical application of these principles and interpretation of nonclinical safety data. Topics will include principles and application of toxicology, carcinogenicity, genetic toxicology, reproduction/developmental toxicology, immunotoxicology, safety pharmacology, statistics, clinical pathology, pathology, biomarkers, PK/ADME, safety evaluation of biotechnology derived products, and regulatory considerations. A workshop of nonclinical assessment and development strategy of a drug taught by distinguished experts in the field of toxicology is also included. For more information and registration forms see the Web site.

Sixth International PCB Workshop—May 30–June 2

The Sixth International PCB Workshop, “Persistent Pollutants Require Persistent Solutions,” will be held May 30–June 2, 2010, Visby, Sweden. Scientists and representatives from agencies involved in the field are invited to make presentations, both oral and in the form of posters. April 10 is the deadline for abstract submissions. Please note that the (oral) platform presentations will be chosen from the abstract submissions. These contributions should clarify the importance of issues related to PCBs and their presence in the environment. The workshop will cover a range of aspects, from analytical issues to the effects of PCBs on the environment and human health. Sessions on how to reduce PCB exposure, including practical and legal implications, will be included. For additional information, visit the workshop Web site.

Twenty-Sixth International Neurotoxicology Conference—June 6–10

The Twenty-Sixth International Neurotoxicology Conference, “Unifying Mechanisms of Neurological Disorders: Scientific, Translational, and Clinical Implications,” will be held June 6–10, 2010, in Portland, Oregon. The abstract deadline for the platform sessions and student poster and travel awards is April 15, 2010. This conference intends to bring together experts from academia, governmental organizations, non-governmental organizations, and industry, from around the world, to discuss the state-of-the-science of what is known, identify information gaps, and help define future directions for research to advance our fundamental knowledge of the causes, mechanisms, diagnosis, related new technologies, treatment, amelioration, and prevention of environmentally-induced or exacerbated diseases and disorders of the nervous system in children and adults. This long-standing conference series has a strong history of convening internationally-recognized experts, neuroscientists, research clinicians, basic scientists, epidemiologists, regulatory scientists, and other informed and interested individuals to provide data and information to draw upon and apply to important scientific, environmental, clinical, treatment, methodological, epidemiological, policy, public health, regulatory, risk assessment, and other contemporary issues related to the theme of the conference. For more information on the 26th International Neurotoxicology Conference including the Overview, Preliminary Program, and Registration, visit the conference Web site.

Teratology Society 50th Annual Meeting—June 26–30

The 50th Annual Meeting of the Teratology Society, “Healthy Lifestyles for Parents and Children,” will be held June 26–30, 2010, Marriott Louisville Downtown, Louisville, Kentucky. This milestone anniversary meeting provides a unique opportunity to celebrate the significant scientific achievements during the past 50 years and to construct the blocks needed to build the future. Cutting edge developments in using high tech biology and informatics for assessment of risk to human development are featured; sessions on maternal nutrition, developmental psychiatry, children’s health are included. The Society is comprised of fellow clinicians, scientists, and science policy regulators, from academic, industrial, and government sectors. This meeting provides an opportunity to promote the shared vision and scientific identity of researchers focused on the causes, manifestations, intervention, and prevention of birth defects, both structural and functional. For more information, please visit the conference Web site.

SOT Members—SOT-Sponsored Meetings—FYI

Februrary 5, 2010

Dear SOT Members:

In addition to hosting the largest toxicology meeting in the world, the 2010 SOT Annual Meeting, March 7–11, 2010, SOT is sponsoring several high-quality meetings that may be of interest to you. Please see the information below and contact the organizers directly if you wish to participate.

Sincerely,

Cheryl Lyn Walker, SOT President


ARA Workshops Advancing Dose-Response Methods—Case Study Nominations Deadline February 20

The Alliance for Risk Assessment (ARA) is planning a series of public workshops to continue discussion on dose-response assessment issues set forth by the NAS’s 2008 document: Science and Decisions: Advancement of Risk Assessment (the silver book). A key component of the workshops will be case studies that illustrate potentially useful dose-response assessment techniques for human health risk assessments of chemicals. Example techniques include: (1) BBDR to address human health risk for a high production volume chemical (e.g., formaldehyde); (2) human health screening approach for data-poor chemicals, as used in U.S. EPA’s Sustainable futures program. We are seeking short proposals for case studies, by February 20. Late proposals may be offered in the meeting, and will also be posted on the Web prior to the meeting. See the Web site for details. Registration is now open for the first workshop, which will be held at the Texas Commission on Environmental Quality (TCEQ), Austin, Texas, on March 16–18, 2010. The meeting can also be attended by webcast. The succeeding two workshops will be held in Fall of 2010 and Spring of 2011. This series of workshops will be highly interactive, with participation from federal, state, industry, NGO, academia, and research institutes. See the Web site for more details. In addition to SOT, the workshop series currently has 18 other sponsors, including professional societies, state environmental agencies, nonprofits, private companies and consortia (see the Web site).

14th International Workshop on QSARs—Early Bird Registration Deadline March 15, 2010.

The 14th International Workshop on Quantitative Structure-Activity Relationships (QSARs) in Environmental and Health Sciences will be held in Montrèal, Canada, May 24–28, 2010. QSAR-2010 intends to bring together modelers and practitioners at various levels to share emerging research results and viewpoints on in silico tools relating to SARs, QSARs and QSPRs for chemicals and pharmaceuticals in the environment regarding: physicochemical properties, environmental fate, toxicokinetics, toxicodynamics, toxicity prediction, and regulatory applications. As part of QSAR-2010, a half-day training course on QSAR-PBPK (physiologically-based pharmacokinetic) modeling, focusing on both ecotoxicology and human health applications, will be offered. The Scientific Program will contain feature presentations on QSARs in the context of the new toxicity testing paradigm and emerging regulatory challenges.

The early-bird registration deadline is March 15, 2010. More details regarding deadlines, accommodation and abstract submission can be found on the Web site or by contacting the Secretariat.

STP/IFSTP 2010 Joint Symposium to Address Neuropathology—June 20–25

The Society of Toxicologic Pathology (STP) in conjunction with the International Federation of Societies of Toxicologic Pathologists (IFSTP) will co-host a symposium on the fundamentals and recent innovations in the field of toxicologic neuropathology, June 20–25, 2010 at the Marriott Downtown Magnificent Mile Hotel, Chicago, Illinois. The focus of this international meeting is to correlate advances in the morphologic evaluation and interpretation of neuropathology findings with functional, cellular, and molecular knowledge in a series of plenary and poster sessions. The major goal of the meeting is to foster an open framework in which to discuss the current state of knowledge of neuropathology evaluations in conventional toxicology and specialized neurotoxicology studies. Foundational sessions will include fundamentals of neurobiology, modern pathology methods for neural investigations, and an interactive panel discussion on “best practices” for brain sampling. The meeting will also provide a unique forum to review the remarkable progress in gene expression, biomarkers, and the role of different glial cell populations in nervous system diseases. A “special problem” session will be dedicated to critical but less understood areas of neuropathology such as the blood-brain barrier, synaptic pathology, and exaggerated pharmacodynamics as a neurotoxic event. The Preliminary Program is available on the Web site.

SOT Science News Alert Oct/Nov

October 21, 2009

Dear SOT Member,

SOT is pleased to sponsor the upcoming meetings described below that are consistent with our vision of “creating a safer and healthier world by advancing the science of toxicology.”

Cheryl Lyn Walker
SOT President

SOT 2010 Annual Meeting Deadlines

SOT Current Concepts in Toxicology (CCT) Meeting

  • PPTOXII: Role of Environmental Stressors in the Development of Origins of Disease, December 7–10, 2009, Loews Hotel, Miami Beach, Florida. The objective of the conference is to examine the animal and human data supporting this hypothesis (developmental basis of disease) disease by disease in order to review the current state of the literature and to identify mechanisms for the effects as well as to identify research gaps and challenges and to integrate the basic and applied science. For additional information, visit the Web site.

Meetings of Groups in which SOT is a Member Organization

  • International Congress of Toxicology

    IUTOX Barcelona 2010—Abstract Deadline January 31, 2010

    IUTOX, AETOX, and EUROTOX, XII International Congress of Toxicology, July 19–23, 2010, Barcelona, Spain, organized by the International Union of Toxicology (IUTOX) in association with The Spanish Association of Toxicology (AETOX), and the Federation of European Toxicologists and European Societies of Toxicology (EUROTOX). The Congress encourages interaction among academia, industry, regulators, human health and environmental toxicologists, basic researchers, developers, and evaluators of new drugs and chemicals. National and international guidelines and regulations require cooperation of all interested parties if new and innovative approaches to safety assessment are to be successful. The abstract deadline is January 31, 2010. For additional information, please visit the meeting Web site.

Sponsored Meetings

  • CDC, NCEH, and ATSDR in conjunction with the National Environmental Health Association, National Environmental Public Health Conference, Healthy People in a Healthy Environment, October 26–28, 2009, Atlanta, Georgia. The 2009 conference aims to develop and encourage innovative strategies for addressing existing and emerging issues and to provide a forum for the Centers for Disease Control and Prevention (CDC), National Center for Environmental Health (NCEH), Agency for Toxic Substances and Disease Registry (ATSDR), and its many partners to share research, scientific, and program information about environmental public health priorities. For more information, please visit the meeting Web site.

  • New York Academy of Sciences, Immunomodulating Therapies and Progressive Multifocal Leukoencephalopathy (PML), November 10, 2009, New York, New York. The aim of this symposium is to provide a forum to discuss whether PML that has been seen in multiple drug trials is a direct consequence of the mechanism of therapeutic action or whether it’s an off-target adverse effect of the therapeutic agent. PML is a rare, but fatal disease that leads to severe brain inflammation and neural demyelination for presenting patients. For additional information, please visit the meeting Web site.

SOT 2010 Annual Meeting and Sponsor Meetings Update

July 21, 2009

Dear SOT Members,

I am writing to remind you of two important deadlines for the 2010 SOT Annual Meeting, which will be held March 7–11, 2010, in Salt Lake City, Utah. In a matter of weeks, the deadlines for Abstract Submissions and Awards Nominations will be upon us, and I hope you will take this opportunity to showcase your scientific research and to acknowledge the achievements of leaders in advancing the science of toxicology. Moreover, consistent with SOT's strategic priority of increasing scientific impact through partnerships with other scientific- and health-based organizations, several upcoming meetings should be of particular interest to you. SOT's next Current Concepts in Toxicology (CCT) meeting, PPTOXII, is sponsored by NIEHS, WHO, U.S. EPA, CDC, NICHD, European Environment Agency, NCTR, Superfund Basic Research Program, NCI, National Institute for Environmental Studies, and IUTOX. SOT also is pleased to sponsor the Non-SOT Meetings described below.

Cheryl Lyn Walker, SOT President

SOT 2010 Annual Meeting Deadlines

SOT Current Concepts in Toxicology

PPTOXII: Role of Environmental Stressors in the Development of Origins of Disease, December 7–10, 2009, Loews Hotel, Miami Beach, Florida. The objective of the conference is to examine the animal and human data supporting this hypothesis (developmental basis of disease) disease by disease in order to review the current state of the literature and to identify mechanisms for the effects as well as to identify research gaps and challenges and to integrate the basic and applied science. Abstract deadline is October 21. For additional information, visit the Web site.

SOT Sponsored Meeting

The Genetic Toxicology Association 2009 Meeting, "Addressing Scientific Challenges Associated with Emerging Regulatory Genetic Toxicology Guidance, Standard Testing Approaches and Genotoxic Impurities," September 9–10, 2009, University of Delaware, Newark, Delaware. A comprehensive program focuses on important emerging issues in genetic toxicology. The abstract deadline is July 30. To submit an abstract, obtain program information, and to register, please visit the Web site.

Environmental Mutagen Society 40th Annual Meeting, "Genomics in the Environmental Century," October 24–28, 2009, St. Louis Union Station Marriott, St. Louis, Missouri. This meeting brings together scientists carrying out basic research with those involved in risk estimate and regulatory concerns related to the consequences of exposure to environmental and pharmaceutical agents. For additional information and to register, please visit the Web site.

SOT Science News Alert—SOT is Pleased to Sponsor These Upcoming Meetings

June 25, 2009

Dear SOT Members,

SOT is pleased to sponsor the upcoming meetings described below that are consistent with our vision of "creating a safer and healthier world by advancing the science of toxicology."

Cheryl Lyn Walker
SOT President

"Benzene 2009: Health Effects and Mechanisms of Bone Marrow Toxicity. Implications for t-AML and the Mode of Action Framework," September 7–11, 2009, Technische Universität München, Munich Germany. A satellite meeting to Eurotox 2009, Benzene 2009 will review the relationship between bone marrow toxicity and leukemia; discuss recent studies on the epidemiology of benzene-induced diseases; explore mechanistic studies of reactive metabolites and reactive oxygen species, transgenics and signal transduction, DNA damage and repair; evaluate exposure metrics and biomarkers; and place the evidence in context using a mode-of-action approach to inform risk assessment. Abstracts for poster and plenary presentations are due by June 30, 2009. Travel fellowships are available for students or postdoctoral researchers. For further information, please the visit Web site.

Safety Pharmacology Society, 9th Annual Meeting, September 15–18, 2009, Strasbourg, France. General information about this scientific meeting targeting the role of safety pharmacology in drug development can be accessed on-line. Presentations cover a spectrum from theory to practical experience and specific case studies. Deadline for scientific abstracts is July 17, 2009. Comprehensive meeting information is available at the SPS Annual Meeting Web site as well as registration and housing information.

4th International Conference on Oxidative/Nitrosative Stress and Disease, October 28–30, 2009, The New York Academy of Sciences, 7 World Trade Center, New York, New York. The aim of the conference is to provide an open forum for the discussion of recent advances related to the cellular and molecular mechanisms mediating the generation of reactive oxygen and nitrogen species and their role in the pathogenesis of human disease, with a particular focus on the respiratory and cardiopulmonary diseases such as asthma, emphysema, and pulmonary hypertension. The conference agenda is now available on-line (click the agenda tab). Deadline for abstract submission is Friday, August 21, 2009. For complete abstract instructions, please contact NYAS via e-mail. Additional meeting information is available at the NYAS Web site.

SOT Science News Alert—February/March Issue

February/March 2009

Toxicological Sciences Forum Series Features Perspectives on Future of Toxicity Testing

SOT Annual Meeting Issue Session—The 'Vision' for Toxicity Testing in the 21st Century: Promises and Conundrums

NAS Symposium on Toxicity Pathway-Based Risk Assessment Announced

2010 Annual Meeting Proposals: Six New Themes

ASTS Will Convene Conference Following SOT Annual Meeting

Opportunity to Take Action: Animals in Research

Upcoming Meetings and Conferences

Non-SOT Meetings—Sponsored by SOT

 

SOT Science News Alert—January Issue

January 2009

SOT Councilors and NICHD Leadership Met To Discuss Opportunities to Work on Areas of Mutual Interest

Nobel Laureate Greengard to Deliver 2009 SOT Annual Meeting Plenary Lecture

Meet the Director of NIEHS and NTP, Linda Birnbaum

NTP to Unveil New Non-Cancer Evaluation Criteria at SOT

Toxicological Sciences Update

NRC Releases Report on Risk Analysis Approaches Used by EPA—Calls for Improvements

SOT Members Eaton and Philbert Lead NRC Committee Reviewing Federal Nanomaterials Research Strategy—Report Available

Non-SOT Meetings—Sponsored by SOT

Opportunity to Take Actions: Petition Urges Congress to Recognize Importance of Journal Revenue to Advancing Science

Update of Guide for the Care and Use of Laboratory Animals—Call for Comments Due January 31, 2009

 

SOT Science News Alert—SOT Past President Linda Birnbaum Named Director of NIEHS

December 3, 2008

Dear SOT Members,

Today it was announced that past SOT Past President, Dr. Linda Birnbaum, has been appointed as the new Director of the National Institute of Environmental Health Sciences (NIEHS). The Office of the Director provides leadership, coordinates initiatives, and oversees the scientific research, administration, and communications for NIEHS and the National Toxicology Program. In addition, the Office of the Director works with other federal agencies, as well as public and private institutes and organizations, to coordinate and support research on environmental health sciences. The mission of NIEHS: "to reduce the burden of human illness and disability by understanding how the environment influences the development and progression of human disease" is closely aligned with our own vision of "creating a safer and healthier world by advancing the science of toxicology."

Dr. Birnbaum joined SOT in 1982 and is a Lifetime Member of the North Carolina Regional Chapter. She served as the 2004–2005 SOT President. In 2007 she received the SOT Public Communications Award and in 2008 she was the first recipient of the Elsevier Mentoring Award conferred by the Women in Toxicology Special Interest Group.

We congratulate NIEHS Director Linda Birnbaum on her appointment. The press release disseminated today is included below.

Sincerely,

Ken Ramos
SOT President

_____________________________________
For Immediate Release
December 3, 2008

Contact:
Christine Flowers
919-541-3665

Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., Named New Director of the National Institute of Environmental Health Sciences

Dr. Raynard S. Kington, acting director of the National Institutes of Health (NIH), today announced the appointment of Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., as director of the National Institute of Environmental Health Sciences (NIEHS). Dr. Birnbaum, who is currently a senior advisor at the Environmental Protection Agency (EPA), where she served for 16 years as director of the Experimental Toxicology Division, will begin her appointment in January 2009.

"I look forward to Dr. Birnbaum joining us," Dr. Kington said. "She has a long and distinguished career conducting research into the health effects of environmental pollutants, and the cause and effects relationships at pollutant concentrations which mimic those occurring in the environment."

As NIEHS director, Dr. Birnbaum will oversee a $730 million budget that funds multidisciplinary biomedical research programs, prevention, and intervention efforts that encompass training, education, technology transfer, and community outreach. NIEHS is located in Research Triangle Park, near Durham, Raleigh, and Chapel Hill, North Carolina. NIEHS currently supports more than 1,240 research grants.

"I am excited about serving as the director of NIEHS at a time when integration across disciplines is essential, from molecular biology to pharmacology and physiology to epidemiology. Complex environmental issues require individual and team efforts to address the interactions between the environment and human health," said Dr. Birnbaum. "Chronic exposures and chronic diseases can have multiple causative factors. A broad array of scientific expertise is needed to understand such problems in order to prevent disease. I am eager to translate the work of the basic scientist and epidemiologist into improvements for the health of our citizens and communities."

A native of New Jersey, Dr. Birnbaum received her M.S. and Ph.D. in microbiology from the University of Illinois, Urbana. A board certified toxicologist, Dr. Birnbaum has served as a federal scientist for nearly 29 years—the first ten of those at NIEHS—first as a senior staff fellow at the National Toxicology Program, then as a principal investigator and research microbiologist, and finally as a group leader for the Institute's Chemical Disposition Group.

Dr. Birnbaum has received numerous awards, including the Women in Toxicology Elsevier Mentoring Award, the Society of Toxicology Public Communications Award, EPA's Health Science Achievement Award and Diversity Leadership Award, and 12 Science and Technology Achievement Awards, which reflect the recommendations of EPA*s external Science Advisory Board, for specific publications. She is the author of more than 600 peer-reviewed publications, book chapters, abstracts, and reports. Dr. Birnbaum's research focuses on the pharmacokinetic behavior of environmental chemicals; mechanisms of actions of toxicants, including endocrine disruption; and linking of real-world exposures to effects. She is also an adjunct professor in the School of Public Health, the Toxicology Curriculum, and the Department of Environmental Sciences and Engineering at the University of North Carolina, Chapel Hill, as well as in the Integrated Toxicology Program at Duke University.

Dr. Birnbaum is also an active member of the scientific community. She is currently president-elect of the International Union of Toxicology, the umbrella organization for toxicology societies in more than 50 countries; former president of the Society of Toxicology, the largest professional organization of toxicologists in the world; former chair of the Division of Toxicology at the American Society of Pharmacology and Therapeutics; and former vice president of the American Aging Association.

NIEHS supports research to understand the effects of the environment on human health and is part of NIH. For more information on environmental health topics, please visit our website at www.niehs.nih.gov.

The National Institutes of Health (NIH)—The Nation's Medical Research Agency—includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.


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