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Thank you for attending the SOT Annual Meeting March 11–15, 2012!

Mark your calendar SOT Annual Meeting March 10–14, 2013.

Submit Session Proposals Now—April 30.


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2011 Annual Meeting Session Proposal Deadline—April 30

The Annual Meeting in Salt Lake City is a good time to work out the details for your session proposals for the 50th Anniversary Annual Meeting in Washington, DC March 6–10, 2011. Proposals will be submitted on-line beginning in early March with a deadline of April 30, 2010.

All proposal submissions will be reviewed for their relevance under the following themes or Continuing Education (CE) target areas for the 2010 Annual Meeting:

Thematic Approach

  • Global Air Quality and Human Health
  • Novel Approaches to Preclinical Safety Assessment: Bridging the Gap Between Discovery and the Clinic Through Translational Toxicology
  • Environment and Disease
  • Toxicity Testing: State of Science and Strategies to Improve Public Health
  • Integration of Toxicological and Epidemiological Evidence to Understand Human Risk
  • Emerging Global Public Health Issues

Continuing Education (CE) Target Areas

  • Cardiovascular Toxicology
  • Epigenetic Mechanisms
  • Systems Biology

Please note that while we are actively soliciting proposals for the themes listed above, all proposal submissions will be reviewed for their timeliness and relevance to the field of toxicology.

The SOT Scientific Program and Continuing Education Committees place great value on the contributions of Specialty Sections and Special Interest Groups (SS/SIGs) in the preparation of high quality proposals for sessions at the SOT Annual Meetings. For this reason, it should be noted that sponsorship and endorsements sought for proposals will continue to be made directly to the SS/SIG(s) by the session organizer prior to submission.

A list of session types with a brief description is posted on-line at the SOT Annual Meeting Web site. Platform and poster abstracts for the 2011 Annual Meeting are due October 3, 2010.

Thematic Approach Descriptions

Global Air Quality and Human Health: It is becoming increasingly apparent that air pollution is not just a local issue, but has international health implications. The goal of this theme is to integrate information on individual susceptibility, disease mechanisms, and levels of exposure and to demonstrate how this information can have a significant impact on the development of global air quality policies and regulations.

Novel Approaches to Preclinical Safety Assessment: Bridging the Gap between Discovery and the Clinic through Translational Toxicology: Toxicology can play a key role in identifying and implementing advances in toxicological mechanisms, safety assessment, and biomarkers when cross-disciplinary efforts are coordinated during the drug development process. The goal of this theme is to highlight advances in toxicology that improve translation from animal models to humans.

Environment and Disease: Growing evidence suggest that the environment is a significant factor in the susceptibility and progression of cardiovascular and neurodegenerative diseases and cancer. The environmental influence on disease theme has been selected to highlight recent advances in these areas as well as contrast how this knowledge is impacting regulation and policy.

Toxicity Testing: State of Science and Strategies to Improve Public Health: In order for Federal regulations to best reflect the current state of the science, toxicity testing paradigms need to adapt to the advances of science. The main challenge inherent in bringing this vision to fruition is to have testing strategies that provide sufficient context for evaluating potential risk. The goal of the toxicity testing theme is to initiate discussion on how toxicity testing could integrate state of the science methodologies and thereby reduce the uncertainties in the interpretation of toxicity-pathway data to humans.

Integration of Toxicological and Epidemiological Evidence to Understand Human Risk: As novel technologies expand the range of biomarker assessments and the NAS vision for toxicity testing begins to be implemented, the integration of mechanistic laboratory animal testing and in vitro systems with human epidemiological data will require new strategies to fully utilize and integrate these data for extending the range of observations and to characterize the exposure-response of human risk. The goal of this theme is to initiate discussion on how new technologies can improve assessment of the dose-response curve and thereby improve human risk assessment from environmental exposures.

Emerging Global Public Health Issues: The global economy raises challenges to protecting human health within the United States for our regulatory agencies. Ultimately, public health issues are no longer just local issues affecting a single country or specific geographic region of the world, but have international health implications. The global public health issues theme has been selected to highlight recent advances in these areas, as well as how this knowledge is impacting regulation and policy.

Continuing Education (CE) Target Areas

Cardiovascular Toxicology: This topic provides an overview of cardiovascular function at the gross and cellular level. It includes descriptions of cellular biochemistry and the impact of toxicants on system components or functions and presents methods and techniques to measure toxicity.

Epigenetic Mechanisms: This topic describes the field of epigenetic mechanisms and reviews fundamental cellular biochemistry. Roles of epigenetic mechanisms in cellular differentiation, aging, disease, therapeutic gene regulation, and toxicity may be presented.

Systems Biology: This topic describes and demonstrates the systems biology approach to the study of chemical mode of action and toxicity. It describes the interdisciplinary nature of the field and provides examples of how a multi-faceted systems biology approach can yield powerful results that both predict and describe the relationship between chemical exposure and cellular/systemic response.


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