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Scientific Sessions

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Scientific Program Overview (dates and times)

To view Scientific Sessions as they are aligned to the 2016 Themes, click here.

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Advances in Neurotoxicology

Developmental Toxicity: Mechanisms and Evaluation

Heath and Environmental Impacts of Man-Made and Naturally Released Toxicants

Molecular Toxicology: Mechanistic Insights and Hazard Assessment

Recent Advances in Safety Assessment

Toxicity of Metals

Monday, March 14

8:00 AM–9:20 AM

Daily Plenary Session—Regenerative Medicine and Tissue Engineering

9:30 AM–12:15 PM

Symposium Session

  • Opening the Black Box: Understanding the Molecular Mechanisms of Developmental Toxicity 

Workshop Sessions

  • Dietary Exposures to Heterocyclic Amines As a Potential Risk Factor for Neurological Disease 
  • Mitochondria As the Central Target of Environmental Contaminants, Pharmaceutical Agents, and Toxicants: Mechanisms of Toxicity and Disease
  • Nanotoxicology and Ocular Drug Delivery: One Size Does Not Fit All
  • Scientific Reproducibility: Does This Pose a Problem for 21st Century Toxicology?  
  • The Cancer Risk Assessment for Ingested Hexavalent Chromium: Challenges and Controversies 
  • Transient Receptor Potential A1 (TRPA1) Cation Channels: Fluttering Hearts, Headaches and Hot Flashes—Can One “Environmental Sensor” Be the Cause of All the Pain? 

Regional Interest Session

  • The Toxicological Implications of the Gulf Oil Spill: Research Accomplishments and Research Needs 

Platform Sessions

  • Investigating Mode of Action in Chemical Carcinogenesis
  • Ozone Research 

9:30 AM–12:45 PM

Poster Sessions

  • Arsenic Toxicity 
  • Bioinformatics and Toxicology 
  • Biomonitoring
  • Cell Death and Apoptosis
  • Immunotoxicology
  • Neurotoxicology of Therapeutic Agents and Abused Substances 
  • Neurotoxicology—Developmental Neurotoxicity 
  • Neurotoxicology—Emerging Technologies for Neurotoxicity Screening 
  • Neurotoxicology—General 
  • Neurotoxicology—Halogenated Hydrocarbons 
  • Respiratory Toxicology
  • Systems Biology and Toxicology 
  • Toxicity of Metal Mixtures 

12:30 PM–1:20 PM

Merit Award Lecture

12:30 PM–1:50 PM

Roundtable Sessions

  • Is a “Thresholdable” Carcinogen Still a Delaney Carcinogen? 
  • Trichloroethylene Exposure and Development of Fetal Cardiac Malformations: What Do the Data Tell Us About Inhalation Exposures Resulting from Vapor Intrusion and Potential Health Risks to Pregnant Women? 

1:15 PM–4:30 PM

Poster Sessions

  • Exposure Assessment
  • Genetic Toxicology I
  • Genetic Toxicology II
  • Mercury Toxicity 
  • Metal Toxicity 
  • Mixtures 
  • Nanotoxicology: General
  • Natural Products 
  • Neurotoxicology—Mercury Neurotoxicity  
  • Neurotoxicology—Metals: Lead, Cadmium, and Others  
  • Ocular Toxicology
  • Safety Assessment: Drug Development 
  • Safety Assessment: Drug Discovery 
  • Toxicology Education

1:30 PM–2:30 PM

Meet the Directors

2:00 PM–4:45 PM

Symposium Sessions

  • Health and Environmental Hazard Assessments of Nanomaterials Along Their Lifecycle
  • The Promise and Reality of Alternative Methods in Inhalation Toxicology and the Development of Inhaled Therapeutics

Workshop Sessions

  • Moving Beyond Prioritization towards True In Vitro-Based Safety Assessment 
  • Quantitative Cumulative Risk Assessment: Is It Feasible Today? 
  • The Role of the Epigenome in Exposure Effects, Susceptibility, and Public Health 
  • Using 21st Century Approaches to Evaluate Endocrine-Active Compounds

Historical Highlights Session

  • Toxicologic Legacies of Major 21st Century Man-Made/Natural Disasters

Platform Sessions

  • AhR and Disease Processes 
  • Pluripotent Stem Cells in Cardiovascular Research

4:45 PM–6:00 PM

SOT/EUROTOX Debate

Tuesday, March 15

8:00 AM–9:20 AM

Daily Plenary Session—Inflammation and Neurodegenerative Disease

9:30 AM–12:15 PM

Symposium Sessions

  • Drug-Induced Taste Change in Clinical Practice and Preclinical Safety Evaluation
  • Genotypic and Intrinsic Risk Factors That Increase Susceptibility to Inhaled Pollutants
  • Systems Understanding of the Impact of the Nrf2 Pathway on Chemical Toxicity and Cell Fate 
  • Unknown, Unknowns: Exploring the Unidentified Fraction of Complex Mixtures

Workshop Sessions

  • Bioactivity-Based Margin of Exposure Safety Assessment: The Next Stop along the Road to 21st Century Safety Assessments 
  • Maternal Exposure to Nanoparticles—How Does It Affect the Fetus? Status, Mechanisms, and Future Directions 
  • Multi-Omics in Predictive Toxicology: Development and Application in Environmental Monitoring Programs 
  • Scientific and Regulatory Advances in Safety Evaluation of Heavy Metals in Food  

Platform Sessions

  • Zebrafish Models: Advances and Applications in DART

9:30 AM–12:45 PM

Poster Sessions

  • Alternative Models: Fish, Worms, and More  
  • Carcinogenesis I
  • Carcinogenesis II
  • Chemical and Biological Weapons 
  • Developmental Basis of Adult Disease 
  • Endocrine Toxiciology
  • Inflammation in Disease
  • Inflammation: Methods and Mechanisms
  • Liver—Mechanisms 
  • Liver—Models
  • Risk Assessment 1
  • Stem Cell Biology and Toxicology
  • Toxic Inhalants Research

12:30 PM–1:20 PM

Leading Edge in Basic Science Award Lecture

1:15 PM–4:30 PM

Poster Sessions

  • 3D Cell and Organ-on-a-Chip Models  
  • Alternative Models for Ocular and Skin Toxicity
  • Biological Modeling
  • Clinical and Translational Toxicology
  • Food Safety/Nutrition 1 
  • Gene Regulation and Signal Transduction 
  • Medical Devices
  • Neurotoxicology—Dopaminergic Systems and Toxicants 
  • Neurotoxicology—Manganese Neurotoxicity  
  • Neurotoxicology—Neurodegenerative Diseases 
  • Neurotoxicology—Pesticide Neurotoxicity 
  • Non-Pharmaceutical Safety Assessment 
  • Oxidative Injury and Redox Biology 
  • Particulate Matter Toxicology
  • Receptors

2:00 PM–4:45 PM

Symposium Sessions

  • New Mechanistic Insights into How the Immune System Drives Hepatic Adverse Drug Reactions
  • Reciprocal Synergism: New Insights into Thyroid Hormone Action in Brain Development and Neurodevelopmental Toxicity  
  • The Role of Gene SLC30A10 on Manganese Homeostasis and Functional Outcomes: Implications for Homeostasis and Neurotoxic  
  • Using Multi- and Transgenerational Effects of Environmental Exposures in Diverse Animal Models for Assessment of Human Health Risks 

Workshop Sessions

  • Cannabis in the Courtroom 
  • Read-Across: Building Scientific Confidence in the Development and Evaluation of Read-Across for Regulatory Purposes Using Tox21 Approaches  
  • Safety Assessment of Topically Exposed Cosmetic Ingredients: Lessons Learned 

Platform Sessions

  • Nanotoxicology: In Vivo
  • Qualification of “New” DART Tools for Hazard Identification 

Wednesday, March 16

8:00 AM–9:20 AM

Daily Plenary Session—Keynote Medical Research Council (MRC) Lecture

9:30 AM–12:15 PM

Symposium Sessions

  • Patient-Specific Stem Cells As Models for Gene, Drug, and Environment Interactions in Disease
  • Sulfur Mustard Poisoning: Mechanisms of Dermal and Pulmonary Toxicity and New Treatment Approaches 

Workshop Sessions

  • An Update on Juvenile Animal Testing 
  • Moving Beyond Cancer: Current State of the Science of Noncancer Health Effects of Arsenic 
  • Paradigm Change in Toxicology: What Will It Take to Bring Advances in the Science of Toxicology into Regulatory Use?  
  • Screening Chemicals for Neurotoxicity Outcomes—Using Large Datasets and Multiple Endpoints to Develop “Toxicity Profiles”  

Informational Session

  • Tox21 Challenge To Build Predictive Models of Nuclear Receptor and Stress Response Pathways As Mediated by Exposure to Environmental Toxicants and Drugs 

Platform Sessions

  • Effects of Food-Associated Agents on Inflammation, Metabolic Disease, and Cancer 
  • Nrf2 in Redox Biology

9:30 AM–12:45 PM

Poster Sessions

  • Autoimmunity/Hypersensitivity
  • Biomarkers
  • Cardiovascular Toxicology
  • Computational and Systems Toxicology I 
  • Computational and Systems Toxicology II 
  • Ecotoxicology
  • Nanotoxicology: In Vitro
  • Nanotoxicology: In Vivo
  • Pesticides
  • Pharmacogenetics/Genetic Polymorphisms 
  • Risk Assessment 2
  • Risk Assessment 3

12:30 PM–1:20 PM

Distinguished Toxicology Scholar Award Lecture

12:30 PM–1:50 PM

Roundtable Session

  • Combination Toxicology: Are We Testing the Right Things?

Informational Sessions

  • Updating FDA’s Redbook: The Importance of Stakeholder Involvement 
  • Why Did the Scientific Program Committee Reject My Proposal? Developing a Good Idea Into an Accepted SOT Session

Education-Career Development Session

  • The Evolution of the Postdoc: Transitioning from Trainee to Professional in the Modern Era

1:15 PM–4:30 PM

Poster Sessions

  • Alternative In Vitro Toxicity Models 
  • Animal Models of Disease
  • Animal Models: Methods and Measurements
  • Cytochrome P450
  • Developmental and Juvenile Toxicology 
  • Developmental Toxicology (Non-Rodent) 
  • Epidemiology and Public Health
  • Epigenetics 
  • Food Safety/Nutrition 2
  • Kidney—Models to Mechanisms and Molecular Biomarkers
  • Liver—Translational
  • Regulation and Policy
  • Reproductive Toxicology 
  • Tobacco Products

2:00 PM–4:45 PM

Symposium Sessions

  • High-Content Imaging for Predictive Toxicology: Discriminating between Adverse and Adaptive Outcomes 
  • Novel Roles of Reactive Oxygen Species (ROS) in Human Diseases: Why ROS Never Gets Stale
  • Use of the Adverse Outcome Pathway (AOP) Concept to Link Epidemiological to Mechanistic Data on the Correlation of Pesticide Exposures and Parkinson’s Disease  

Workshop Sessions

  • Advanced Techniques in PBPK Modeling to Improve Quantitative Risk Assessment for Infants and Children ♞ 
  • “Breaking Bad”: Cardiovascular Autophagy Gone Rogue: A Putative Mechanism of Toxicity and a Drug Target in Disease
  • In Vitro Dosimetry of Engineered Nanomaterials: Too Complicated to Consider, Too Important to Ignore
  • Medical Device Biomaterials: Challenges in Assessing the Toxicity and Biocompatibility of Nanomaterials, Bioabsorbables, and Tissue Scaffolds

Platform Sessions

  • Heavy Metals: Mechanisms and Disease Pathogenesis 
  • Innovations in Toxicology Education

5:00 PM–6:20 PM

Education-Career Development Session

  • “Talksicology”: Effective Oral Presentation Techniques

5:00 PM–5:50 PM

Translational Impact Award Lecture

5:00 PM–6:20 PM

Society of Toxicology–Japanese Society of Toxicology Mini-Symposium

  • Advances in Metal Toxicity
    Lecturer: Michael Aschner, Albert Einstein College of Medicine, Bronx NY; and Yoshito Kumagai, University of Tsukuba, Tsukuba, Japan.

Thursday, March 17

9:30 AM–12:15 PM

Symposium Session

  • Mitochondrial Dysfunction as a Pathogenic Mechanism and Therapeutic Target for Neurodegenerative Diseases  

Workshop Sessions

  • Beyond Benchmark Dose: Advancing Probabilistic and Bayesian Approaches in Hazard Characterization 
  • Bringing More Science into the Process of Risk Assessment for Endogenous Chemicals with Exogenous Exposures 
  • Developmental Immunotoxicology—Are We Adequately Evaluating Safety? 
  • Potential Health and Environmental Effects of Unconventional Hydraulic Fracturing 
  • Which Human Cell Lines Should I Use? Choosing the Appropriate Biological Systems for High-Throughput Toxicity Testing 

Platform Sessions

  • Advances in Mammary Gland Biology and Toxicology
  • Electronic Cigarette Research
  • Flame Retardants

9:30 AM–12:45 PM

Poster Sessions

  • Biotransformation
  • Disposition and Pharmacokinetics
  • Emerging Technologies
  • MicroRNA Biomarkers 
  • Nanotoxicology—Carbon Based
  • Persistent Organic Pollutants 
  • Skin Responses and Toxicology

Late-Breaking Poster Session