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Thematic Approach

The Scientific Program Committee has developed a slate of timely and highly informative Symposium Sessions, Workshop Sessions, Roundtable Sessions, and other special sessions that span the spectrum of topics of interest to our diverse membership.

The 2016 scientific themes listed here illustrate the core contributions toxicology makes to these areas and the sessions that will be highlighted within these themes are indicated.

Thematic Icon Key:

Advances in Neurotoxicology

Developmental Toxicity: Mechanisms and Evaluation

Heath and Environmental Impacts of Man-Made and Naturally Released Toxicants

Molecular Toxicology: Mechanistic Insights and Hazard Assessment

Recent Advances in Safety Assessment

Toxicity of Metals

Advances in Neurotoxicology 

  • Cannabis in the Courtroom—Workshop Session
  • Dietary Exposures to Heterocyclic Amines As a Potential Risk Factor for Neurological Disease—Workshop Session
  • Mitochondrial Dysfunction As a Pathogenic Mechanism and Therapeutic Target for Neurodegenerative Diseases—Symposium Session
  • Neurotoxicology of Therapeutic Agents and Abused Substances—Poster Session
  • Neurotoxicology—Developmental Neurotoxicity—Poster Session
  • Neurotoxicology—Dopaminergic Systems and Toxicants—Poster Session
  • Neurotoxicology—Emerging Technologies for Neurotoxicity Screening—Poster Session
  • Neurotoxicology—General—Poster Session
  • Neurotoxicology—Halogenated Hydrocarbons—Poster Session
  • Neurotoxicology—Manganese Neurotoxicity—Poster Session
  • Neurotoxicology—Mercury Neurotoxicity—Poster Session
  • Neurotoxicology—Metals: Lead, Cadmium, and Others—Poster Session
  • Neurotoxicology—Neurodegenerative Diseases—Poster Session
  • Neurotoxicology—Pesticide Neurotoxicity—Poster Session
  • Reciprocal Synergism: New Insights into Thyroid Hormone Action in Brain Development and Neurodevelopmental Toxicity—Symposium Session
  • Screening Chemicals for Neurotoxicity Outcomes—Using Large Datasets and Multiple Endpoints to Develop “Toxicity Profiles”—Workshop Session
  • The Role of Gene SLC30A10 on Manganese Homeostasis and Functional Outcomes: Implications for Homeostasis and Neurotoxicity—Symposium Session
  • Transient Receptor Potential A1 (TRPA1) Cation Channels: Fluttering Hearts, Headaches and Hot Flashes—Can One “Environmental Sensor” Be the Cause of All the Pain?—Workshop Session
  • Use of the Adverse Outcome Pathway (AOP) Concept to Link Epidemiological to Mechanistic Data on the Correlation of Pesticide Exposures and Parkinson’s Disease—Symposium Session

Developmental Toxicity: Mechanisms and Evaluation 

  • Advanced Techniques in PBPK Modeling to Improve Quantitative Risk Assessment for Infants and Children—Workshop Session
  • An Update on Juvenile Animal Testing—Workshop Session
  • Developmental and Juvenile Toxicology—Poster Session
  • Developmental Basis of Adult Disease—Poster Session
  • Developmental Immunotoxicology—Are We Adequately Evaluating Safety?—Workshop Session
  • Developmental Toxicology (Non Rodent)—Poster Session
  • Embryology and Developmental Toxicity Testing—Continuing Education Course (AM06)
  • Maternal Exposure to Nanoparticles—How Does It Affect the Fetus? Status, Mechanisms, and Future Directions—Workshop Session
  • Qualification of “New” DART Tools for Hazard Identification—Platform Session
  • Opening the Black Box: Understanding the Molecular Mechanisms of Developmental Toxicity—Symposium Session
  • Reciprocal Synergism: New Insights into Thyroid Hormone Action in Brain Development and Neurodevelopmental Toxicity—Symposium Session
  • Reproductive Toxicology—Poster Session
  • Trichloroethylene Exposures Resulting from Vapor Intrusion: What Do the Data Tell About Potential Health Risks to Pregnant Women—Roundtable Session
  • Using Multi- and Transgenerational Effects of Environmental Exposures in Diverse Animal Models for Assessment of Human Health Risks—Symposium Session

Health and Environmental Impacts of Man-Made and Naturally Released Toxicants 

  • Advancing the Detection, Imaging, and Pitfalls in Monitoring Oxidative Stress in Health and Disease—Continuing Education Course (AM02)
  • AhR and Disease Processes—Platform Session
  • Approaches to Investigate and Assess Risks Associated with Drug-Induced Liver Injury (DILI)—Continuing Education Course (PM08)
  • Chemical and Biological Weapons—Poster Session
  • Effects of Food-Associated Agents on Inflammation, Metabolic Disease, and Cancer—Platform Session
  • Food Safety/Nutrition 1—Poster Session
  • Genetics and Population Variability in Chemical Toxicity: The What, the How, and So What?—Continuing Education Course (PM10)
  • Health and Environmental Hazard Assessments of Nanomaterials Along Their Lifecycle—Symposium Session
  • Human Health Risk Assessment: A Case Study Application of Principles—Continuing Education Course (PM11)
  • Mixtures—Poster Session
  • Natural Products—Poster Session
  • One Toxicological Health: Environmental Chemicals and Their Impacts on Humans, Laboratory Animals, and Wildlife—Workshop Session
  • Ozone Research—Platform Session
  • Persistent Organic Pollutants—Poster Session
  • Potential Health and Environmental Effects of Unconventional Hydraulic Fracturing—Workshop Session
  • Sulfur Mustard Poisoning: Mechanisms of Dermal and Pulmonary Toxicity and New Treatment Approaches—Symposium Session
  • The Toxicological Implications of the Gulf Oil Spill: Research Accomplishments and Research Needs—Regional Interest Session
  • Toxicologic Legacies of Major 21st Century Man-Made/Natural Disasters—Historical Highlights
  • Zebrafish As a Tool in Toxicology and Drug Discovery Screening—Continuing Education Course (PM13)

Molecular Toxicology: Mechanistic Insights and Hazard Assessment 

  • 3D Cell and Organ-on-a-Chip Models—Poster Session
  • Advancing the Detection, Imaging, and Pitfalls in Monitoring Oxidative Stress in Health and Disease—Continuing Education Course (AM02)
  • Adverse Outcome Pathway (AOP) Development and Evaluation—Continuing Education Course (AM03)
  • Alternative Models: Fish, Worms, and More—Poster Session
  • Basic Principles and Practices for Applying Epigenetics in Mechanistic Toxicology—Continuing Education Course (SR01)
  • Contribution of Mitochondria to Drug-Induced Organ Toxicities—Continuing Education Course (AM04)
  • Discovery and Validation of miRNA Biomarkers Bridging Preclinical and Clinical Toxicity: Lessons Learned from Hepatotoxicity—Continuing Education Course (AM05)
  • Epigenetics—Poster Session
  • Gene Regulation and Signal Transduction—Poster Session
  • Genetics and Population Variability in Chemical Toxicity: The What, the How, and So What?—Continuing Education Course (PM10)
  • High-Content Imaging for Predictive Toxicology: Discriminating between Adverse and Adaptive Outcomes—Symposium Session
  • Liver—Mechanisms—Poster Session
  • MicroRNA Biomarkers—Poster Session
  • Multi-Omics in Predictive Toxicology: Development and Application in Environmental Monitoring Programs—Workshop Session
  • Next-Generation Sequencing in Toxicogenomics—Continuing Education Course (AM07)
  • Opening the Black Box: Understanding the Molecular Mechanisms of Developmental Toxicity—Symposium Session
  • Oxidative Injury and Redox Biology—Poster Session
  • Paradigm Change in Toxicology: What Will It Take to Bring Advances in the Science of Toxicology into Regulatory Use?—Workshop Session
  • Pharmacogenetics/Genetic Polymorphisms—Poster Session
  • Read-Across: Building Scientific Confidence in the Development and Evaluation of Read-Across for Regulatory Purposes Using Tox21 Approaches—Workshop Session
  • Scientific Reproducibility: Does This Pose a Problem for 21st Century Toxicology?—Workshop Session
  • Screening Chemicals for Neurotoxicity Outcomes—Using Large Datasets and Multiple Endpoints to Develop “Toxicity Profiles”—Workshop Session
  • Systems Understanding of the Impact of the Nrf2 Pathway on Chemical Toxicity—Symposium Session
  • Tox21 Challenge To Build Predictive Models of Nuclear Receptor and Stress-Response Pathways As Mediated by Exposure to Environmental Toxicants and Drugs—Informational Session
  • The Role of the Epigenome in the Exposure Effects, Susceptibility, and Public Health—Workshop Session
  • Use of the Adverse Outcome Pathway (AOP) Concept to Link Epidemiological to Mechanistic Data on the Correlation of Pesticide Exposures and Parkinson’s Disease—Symposium Session

Recent Advances in Safety Assessment 

  • 3D Cell and Organ-on-a-Chip Models—Poster Session
  • Advanced Techniques in PBPK Modeling to Improve Quantitative Risk Assessment for Infants and Children—Workshop Session
  • Adverse Outcome Pathway (AOP) Development and Evaluation—Continuing Education Course (AM03)
  • Alternative In Vitro Toxicity Models—Poster Session
  • Alternative Models: Fish, Worms, and More—Poster Session
  • Approaches to Investigate and Assess Risks Associated with Drug-Induced Liver Injury (DILI)—Continuing Education Course (PM08)
  • Beyond Benchmark Dose: Advancing Probabilistic and Bayesian Approaches in Hazard Characterization—Workshop Session
  • Bioactivity-Based Margin of Exposure Safety Assessment: The Next Stop along the Road to 21st Century Safety Assessments—Workshop Session
  • Bioinformatics and Toxicology—Poster Session
  • Bringing More Science into the Process of Risk Assessment for Endogenous Chemicals with Exogenous Exposures—Workshop Session
  • Computational and Systems Toxicology I—Poster Session
  • Computational and Systems Toxicology II—Poster Session
  • Discovery and Validation of miRNA Biomarkers Bridging Preclinical and Clinical Toxicity: Lessons Learned from Hepatotoxicity—Continuing Education Course (AM05)
  • Exploring Chemical Space in the New Toxicity Testing Paradigm: From Data Curation to Computational Simulations—Continuing Education Course (PM09)
  • Is a “Thresholdable” Carcinogen Still a Delaney Carcinogen?—Roundtable Session
  • Moving Beyond Prioritization towards True In Vitro Based Safety Assessment—Workshop Session
  • Next-Generation Sequencing in Toxicogenomics—Continuing Education Course (AM07)
  • Non-Pharmaceutical Safety Assessment—Poster Session
  • Paradigm Change in Toxicology: What Will It Take to Bring Advances in the Science of Toxicology into Regulatory Use?—Workshop Session
  • Quantitative Cumulative Risk Assessment: Is It Feasible Today?—Workshop Session
  • Read-Across: Building Scientific Confidence in the Development and Evaluation of Read-Across for Regulatory Purposes Using Tox21 Approaches—Workshop Session
  • Safety Assessment of Topically Exposed Cosmetic Ingredients: Lessons Learned—Workshop Session
  • Safety Assessment—Drug Development—Poster Session
  • Safety Assessment—Drug Discovery—Poster Session
  • Systems Biology and Toxicology—Poster Session
  • Scientific and Regulatory Advances in Safety Evaluation of Heavy Metals in Food—Workshop Session
  • Scientific Reproducibility: Does This Pose a Problem for 21st Century Toxicology?—Workshop Session
  • Unique Approaches to Safety Assessment of Gene, Cell, and Nucleic Acid-Based Therapies—Continuing Education Course (PM12)
  • Updating the FDA’s RedBook: The Importance of Stakeholder Involvement—Informational Session Session
  • Using 21st Century Approaches to Evaluate Endocrine-Active Compounds—Workshop Session
  • Which Human Cell Lines Should I Use? Choosing the Appropriate Biological Systems for High-Throughput Toxicity Testing—Workshop Session
  • Zebrafish As a Tool in Toxicology and Drug Discovery Screening—Continuing Education Course (PM13)

Toxicity of Metals 

  • Arsenic Toxicity—Poster Session
  • Heavy Metals: Mechanisms and Disease Pathogenesis—Platform Session
  • Mercury Toxicity—Poster Session
  • Metal Toxicity—Poster Session
  • Mitochondrial Dysfunction As a Pathogenic Mechanism and Therapeutic Target for Neurodegenerative Diseases—Symposium Session
  • Moving Beyond Cancer: Current State of the Science of Noncancer Health Effects of Arsenic—Workshop Session
  • Neurotoxicology—Manganese Neurotoxicity—Poster Session
  • Neurotoxicology—Mercury Neurotoxicity—Poster Session
  • Neurotoxicology—Metals: Lead, Cadmium, and Others—Poster Session
  • Scientific and Regulatory Advances in Safety Evaluation of Heavy Metals in Food—Workshop Session
  • The Cancer Risk Assessment for Ingested Hexavalent Chromium: Challenges and Controversies—Workshop Session
  • The Role of Gene SLC30A10 on Manganese Homeostasis and Functional Outcomes: Implications for Homeostasis and Neurotoxicity—Symposium Session
  • Toxicity of Metal Mixtures—Poster Session