MicroRNAs (miRNAs) are small, regulatory RNAs that control gene expression posttranscriptionally, thus acting as epigenetic regulators within cells. Recent data demonstrates that some miRNAs are specific to or enriched in certain cell types and/or organs and that they are released upon cellular damage, supporting their potential as non-invasive biomarkers of injury. Ease of detection and high stability at room temperature in biofluids contribute to enthusiasm of miRNAs as non-invasive biomarkers. MiRNA detection is relatively straightforward with low inputs of material by quantitative real-time-PCR, microarray, or next-generation sequencing.
Several consortia efforts have been established to discover and validate miRNA biomarkers that:
Critically, several of these biomarkers, particularly for liver injury, have progressed to clinical validation. Communication of recent discovery efforts and discussion of miRNA biomarker research efforts between consortia partners and independent researchers is a critical step toward the streamlined utilization of promising biomarkers for nonclinical and clinical safety assessment.
In an effort to be environmentally conscious, registrants are encouraged to use the online miRNA resources to view conference materials. Use these options to download materials to your computer, smartphone, or tablet.
The CCT: MiRNA Biomarkers for Toxicology Meeting will be held in the Ernest N. Morial Convention Center on Saturday, March 12, 2016. CCT registrants are encouraged to participate in the 55th Annual Meeting that will be held March 13–17. Separate registration is required. Visit the Annual Meeting website for more information.
Room 207—New Orleans Convention Center
New Orleans, Louisiana
March 12, 2016
Meeting attendees may book their housing reservations through the SOT Annual Meeting housing reservation system. You may contact Connections Housing directly at 800.262.9974 or 404.842.0000, 9:00 am–7:00 pm EST Monday through Friday. You benefit when you book your hotel room within the room block by receiving significantly reduced hotel rates and superior reservation services.
Deadline: February 12, 2016
|Registrant Type||Pre-Registration||Standard Registration||Final Registration|
|Received by Jan 15||
Jan 16–Feb 12
After Feb 12
Registrants for this meeting are encouraged to also attend the AM05: Discovery and Validation of miRNA Biomarkers Bridging Preclinical and Clinical Toxicity: Lessons Learned from Hepatotoxicity CE Course. There is an additional fee to participate in the course. You may register for the course at the time of your CCT registration. This CE Course will be held on Sunday, March 13 as part of the SOT Annual Meeting.
SOT Members and Nonmembers alike are encouraged to use SOT’s online registration system. Please select the appropriate registration option below to get started.
Online Registration for 2016 SOT Annual Meeting & CCT Meeting: Attendees who intend to register for both the SOT Annual Meeting and CCT Meeting should use this option. Please note that in order to successfully register for the CCT Meeting, registrants will need to select the “miRNA Biomarkers for Toxicology CCT Meeting” option from the listing of Sessions in the registration system.
Online Registration for CCT Meeting Only: Attendees who will only register for the miRNA Biomarkers for Toxicology Meeting should use this option.
*Please note that attendees not attending the SOT Annual Meeting may register for the AM05: Discovery and Validation of miRNA Biomarkers Bridging Preclinical and Clinical Toxicity: Lessons Learned from Hepatotoxicity CE Course using the CCT Meeting registration system. If you are attending the SOT Annual Meeting, you are encouraged to make your CE Course registrations with your SOT Annual Meeting registration.
You are encouraged to contact SOT Headquarters via email or via telephone 703.438.3115, with any questions about the registration process.
Registration Cancellation Refund Policy: All requests for cancellations and/or refunds must be received in writing to SOT Headquarters by February 12, 2016. These refunds will be processed, less a $30 fee, following the meeting.
Disabled Attendees: If you need special assistance for this meeting please contact SOT Headquarters at 703.438.3115.
Note: For individuals who are not members of SOT, participation in SOT’s miRNA Biomarkers of Toxicology meeting is available only to bona fide individuals who are engaged in or promote the field of toxicology or biotechnology research and support the growth and development of the toxicology field. For organizations, participation in the SOT’s miRNA Biomarkers of Toxicology meeting is available only to bona fide organizations with public policy positions and business practices that are generally consistent with SOT’s mission, goals, reputation, and its policies and principles as determined by SOT. SOT reserves the right to review applications for participation at SOT’s miRNA Biomarkers of Toxicology meeting to confirm that the applicant meets these criteria and may, at the SOT’s sole discretion, reject a registration by an individual or business or withdraw registration privileges at any time if any individual or organization is found to be inconsistent with SOT’s principles and interests.
There will be a 90 minute poster session as part of the lunch break during the meeting. The poster session will be held in Convention Center Room 217.
Prior to the meeting attendees will be able to download accepted abstracts and poster presentations submitted by presenters.
KEYNOTE LECTURE—9:00 AM–10:00 AM
About Chomsky, DNA Patterns, non-Coding RNAs and Cancer Patients
George Calin, MD Anderson Cancer Center, Houston, TX
PLENARY SESSION I: MiRNAs as Biomarkers of Tissue Injury or Disease across Organ
Systems—10:00 AM–1:00 PM
Heidrun Ellinger-Ziegelbauer, Bayer Pharma AG, Wuppertal, Germany
Igor Pogribny, US FDA-NCTR, Jefferson, AR
LUNCH AND POSTER SESSION—1:00 PM–2:30 PM
90 minute poster session and lunch.
Convention Center Room 217
PLENARY SESSION II: Technical Considerations for Measurement and Analysis of Small Non-Coding RNA in Biofluids—2:30 PM–5:30 PM
Karol Thompson, US FDA, Silver Spring, MD
Michael Lawton, Pfizer, Groton, CT
Alison Harrill, University of Arkansas for Medical Sciences, Little Rock, AR
Warren Glaab, Merck, West Point, PA
Meeting attendees also will have the opportunity to attend the AM05: Discovery and Validation of miRNA Biomarkers Bridging Preclinical and Clinical Toxicity: Lessons Learned from Hepatotoxicity CE Course on Sunday morning.
If you plan to attend the SOT Annual Meeting please register for the CE Course as part of your SOT Annual Meeting registration.
If you will only be attending the miRNA Biomarkers for Toxicology Meeting you may register for the CE Course as part of your CCT Meeting registration.
Please visit the SOT Annual Meeting website for complete information on New Orleans.