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“Animal vs. Human Models of Toxcity Testing”

National Capital Area Chapter

Society of Toxicology

Fall Symposium

Tuesday, May 20, 2008

Lister Hill Auditorium

National Library of Medicine

Bethesda, MD


8:30 AM Registration and Continental Breakfast
9:00 AM

Welcome/Opening Remarks

Gary Burin, MPH, Ph.D., DABT President, NCAC-SOT

9:10 AM

Predictive Teratology: Lessons Learned and Current Applications
Karen Augustine, Ph.D., Research Fellow, Drug Safety-Pre Clinical Optimization, Bristol Myers Squibb Research Institute

10:00 AM

The Rodent Chronic Assay Database for Pesticides: Using Mode of Action Data to Assess the Human Relevance of Animal Tumors
Vicki Dellarco, Ph.D., Senior Science Advisor, Office of Pesticide Program, U.S. EPA

10:50 AM Break
11:10 AM

Use of Transgenics in Carcinogenicity Testing
Richard Storer, Ph.D., Senior Scientific Director, Dept. of Laboratory Sciences and Investigative Toxicology, Safety Assessment, Merck Research Laboratories

12:00 PM Lunch (Box lunch and beverage included in registration fee)
1:00 PM Hepatotoxicity Testing: Predictive Strengths and Weaknesses
Rich Miller, DVM, Ph.D., DACVP, VP, Safety Assessment, GlaxoSmithKline
1:50 PM Break
2:10 PM The Generation and Use of Human Data in the Safety Evaluation of Pesticides, Personal Care Products, Food Ingredients and Pharmaceuticals
Gary Burin, MPH, Ph.D., DABT, President, NCAC-SOT and Director, Toxicology and Risk Assessment, Technology Sciences Group Inc.
3:00 PM ToxCast: One Step in Fulfilling the Vision of Toxicity Testing in the
21st Century
Robert Kavlock, Ph.D., Director, National Center for Computational Toxicology, Office of Research and Development, U.S. EPA
3:50 PM Closing Remarks
Donna Mendrick, Ph.D. Vice-President, NCAC-SOT and Program Chair
4:00 PM Meeting Adjourned






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