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Ohio Valley Tele-Seminar: Cellular Responses to Endogenous Oxidative Damage

The Ohio Valley Society of Toxicology Is Pleased to Present:

Larry J. Marnett, Ph.D.
Director of the Vanderbilt Institute of Chemical Biology
Mary Geddes Stahlman
Professor of Cancer Research Professor of Biochemistry and Chemistry

Cellular Responses to Endogenous Oxidative Damage
Thursday, May 11, 2006, 12:00 NOON–1:00 PM EST

Dr. Marnett’s Presentation

Dr. Marnett received his Ph.D. in Chemistry from Duke University in 1973 and did postdoctoral work at the Karolinska Institute and Wayne State University. He began his academic career at Wayne State University where he rose through the ranks to Professor of Chemistry. In 1989, he moved to Vanderbilt. Marnett’s research program focuses on the role of the enzyme cyclooxygenase-2 in cancer and inflammation as well as on the contribution of normal metabolism to the generation of DNA damage and mutation. His group has used structure-based based approaches in conjunction with medicinal chemistry to design selective cyclooxygenase-2 inhibitors as potential anti-inflammatory, cancer preventive, and anti-angiogenic agents. Included in the awards Marnett has received are The Wayne State University President’s Award for Excellence in Teaching, the American Cancer Society Faculty Research Award, the Sigma Xi Research Award, the Michigan Association of Governing Boards Distinguished Faculty Award, the Wayne State University Distinguished Graduate Faculty Award, an Outstanding Investigator Award from the National Cancer Institute, the Harvey Branscomb Distinguished Professorship, and the Stanley Cohen Prize at Vanderbilt University. He is a Fellow of the American Association for the Advancement of Science. He is the author of over 310 research publications and 10 patents. He is the founding and current editor-in-chief of the American Chemical Society journal, Chemical Research in Toxicology. Marnett served as Associate Director of Basic Research of the Vanderbilt Ingram Cancer Center from 1993–2002 and was named Director of the Vanderbilt Institute of Chemical Biology in 2002.

Dr. Marnett will present the seminar via telephone conference bridge. After the presentation, there will be a question and answer session.

A link for downloading Dr. Marnett’s presentation and a call-in number will be provided one week before the seminar.

To familiarize yourself with the subject matter of Dr. Marnett’s upcoming talk please follow the link provided below:

West, J.D., Marnett, L.J.
Endogenous reactive intermediates as modulators of cell signaling and cell death. Chem Res Toxicol. 2006 Feb;19(2):173–94.