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Assessing the Hazards of Fluoropolymers, a Class of Per- and Polyfluoroalkyl Substances (PFAS)

Date: Tuesday, February 27, 2018
Time: 11:00 am–12:00 noon Eastern Time
Link for Attendees: Click Here (Registration Required)
Speaker: Barbara Henry, PhD, Toxicologist, W.L. Gore and Associates

Brief Abstract: This webinar will be of interest to all toxicologists who perform toxicological risk assessments. The regulation of per- and poly-fluoroalkyl substances (PFAS) is a growing topic of interest, due in part to the widespread detection of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). Some believe the most appropriate approach to PFAS regulation or consideration of their potential risks is to lump together both polymeric and non-polymeric categories, treating them as if they were a single class of substances. Fluoropolymers become aggregated into the highly broad PFAS classification without regard to distinct characteristics that qualify them as meeting the globally accepted criteria for Polymers of Low Concern (OECD, 2009; BIO by Deloitte, 2015).

A new paper, in review for publication in Integrated Environmental Assessment and Management (IEAM), is intended to drive further clarity on the broad group of chemistry known as PFAS. The authors conducted a thorough review of the regulatory history of the hazard assessment of polymers and non-polymers, as well as the scientific foundation for the resulting paradigm ("polymers of low concern"), and they articulate a clear and compelling scientific basis for segregating fluoropolymers from other PFAS. Separation of fluoropolymers from the larger list of thousands of substances grouped into five different classes of PFAS is based upon the authors' demonstration that fluoropolymers constitute a distinct class within the PFAS group and, therefore, should be considered separately for hazard assessment or regulatory purposes. The paper further establishes that grouping fluoropolymers with all classes of PFASs for "read-across" or structure-activity relationship assessment is not scientifically appropriate, when a complete, good quality data set exists, as it does for fluoropolymers.

In Vitro Testing: Tales from the Real World
Continuing Education Course AM06

Date: Sunday, March 11, 2018
Time: 8:15 am–12:00 pm
Location: Convention Center, location CC Room 302

Evaluation of Leachable Substances from Materials with Applications in Foods and Pharmaceuticals: Science and Risk Based Approaches
Continuing Education Course PM10

Date: Sunday, March 11, 2018
Time: 1:15 am–5:00 pm
Location: Convention Center, location CC Room 302

MDCPSS Executive Officers Meeting

Date: Monday, March 12, 2018
Time: 8:00 am–9:00 am
Location: Hilton River’s Edge Cafe & Patio Bar

MDCPSS Mentoring Event

Date: Tuesday, March 13, 2018
Time: 5:00 pm–6:00 pm
Location: Grand Hyatt Texas E

MCDPSS Evening Reception

Date: Tuesday, March 13, 2018
Time: 6:00 pm–7:30 pm
Location: Grand Hyatt Texas E

Matching Analytical Methods to Markets: Balancing Regulatory Expectations and Technical Challenges

Date: Wednesday, March 14, 2018
Time: 8:00 am–10:45 am
Location: Convention Center, location CC Hemisfair Ballroom C3

Poster Session: Medical Devices
Poster Session tour mentoring event

Date: Tuesday, March 13, 2018
Author Attended Time: 9:15 am–10:45 am, Poster is available until 4:30pm.
Location: CC Exhibit Hall


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