The Committee on Diversity Initiatives (CDI) is pleased to spotlight the following outstanding toxicologists. Selected from a national applicant pool to attend the Undergraduate Diversity Program at one of the past SOT Annual Meetings, these scientists share more about their lives since their introduction to toxicology at SOT.
Other participants in the SOT Undergraduate Diversity Program are encouraged to touch base with Rachel Woodson at SOT Headquarters to share your career path.
|Undergraduate Education Program Honoree: 2001
Current Position: USDA Research Plant Physiologist & Adjunct Assistant Professor at Purdue University
2005: BS Biology, Morgan State University
2006: MS Biotechnology with a concentration in Biodefense, the Johns Hopkins University
2011: PhD, Molecular Tree Physiology-Genetics, Purdue University
In 2001, Shaneka received an undergraduate travel award to attend the Society of Toxicology (SOT) Annual Meeting with Dr. Dwayne Hill, a professor at MSU and a SOT member. Shaneka was most fascinated with the way chemicals and toxins worked within the body. After graduating with highest honors from MSU with a BS in Biology and minors in Chemistry, English, and Spanish, Shaneka obtained laboratory manager positions at Johns Hopkins University in human genetics and neuroscience to gain both larger skillset and experience with additional model systems.
Inspired by the effects of chemicals and mutagens on those model systems, Shaneka received a Master’s in Biotechnology with a concentration in Biodefense from Johns Hopkins University,
Shaneka achieved her PhD in Molecular Tree Physiology and Genetics at Purdue University in 2011, learning how plants were able to create and produce chemicals and how they could be genetically modified. She genetically engineer several plant species to use less water, tolerate greater amounts of salt, and to overproduce wax by overexpressing a single gene for each result.
Shaneka accepted a position with the USDA Forest Service (USDA-FS) to work on Acacia koa (koa) in Hawai’i. Koa is a tree species endemic to the all islands within the Hawaiian archipelago whose numbers are severely declining because of disease, invasive pests, and climate change. Shaneka’s research uses NextGeneration technologies to uncover genes and proteins involved in climate, pest, and altitude adaptation.
Shaneka works diligently with diversity groups on the Purdue University and with the American Society for Plant Biology Minority Affairs Committee to support and encourage other minorities working in plant biology. She is an adjunct faculty member in the Department of Forestry and Natural Resources at Purdue University and the Special Emphasis Program Manager for African-American programs at the USDA-FS Northern Research Station.
Shaneka has returned to MSU to speak with students about career options and the value of attending conferences. She continues to support the efforts of young minority scientists in a variety of fields with which she is experienced and often serves as a science fair and research competition judge on the local and national scale.
Undergraduate Education Program for Minority Students Honoree: 2005
During Ebany’s graduate career she was co-mentored by Drs. Andrea Allan and Jim Liu. Her dissertation examined the effect of moderate exposure to arsenic (As) during the perinatal period on learning and memory behavior in adolescence. The project resulted in three first-authored publications, the first reported learning and memory deficits and elevated stress levels produced by exposure to environmentally relevant concentrations of As (50ppb) (Martinez, 2008). The second reported the impact of As-exposure on other stress axis parameters known to mediate memory behavior (Martinez-Finley, 2009) and the third reported the dramatic downstream effect of the altered stress axis (Martinez-Finley, 2011). Ebany was supported by a fellowship from Pfizer and an F31 NRSA and was the recipient of four grants funded by the NM legislature. During this period, Ebany received several awards for travel and oral presentations of her work and she served as a teaching assistant for pharmacy and medical students and taught an undergraduate health sciences lab. While Ebany had experienced many facets of research by this point she had yet to explore toxicology from the industry perspective so she took an internship at Pfizer under the direction of Dr. Tiffini Brabham. Her project assessed ways to characterize drug-induced neuropathy through behavioral analysis.
After graduation, Ebany moved to Nashville to start postdoctoral work in the lab of Dr. Michael Aschner at Vanderbilt. Her research is focused on methylmercury toxicity and neurodegeneration. She currently serves as the Junior Co-chair for the Postdoctoral Association at Vanderbilt and as the Secretary for the Postdoctoral Assembly of SOT.
|Undergraduate Education Program for Minority Students Honoree: 1999
Current Position: Toxicologist II, Global Product Safety, Kimberly-Clark Corporation
2001: BS in Chemistry (minor in Biology), Paine College
2005: PhD in Pharmacology and Toxicology, Virginia Commonwealth University
Kristini knew she wanted to gain a better understanding of toxic mechanisms of action and how to utilize in vitro techniques in correlating clinical outcomes in vivo. During her laboratory rotations in the department of Pharmacology and Toxicology, she identified her advisor, Dr. Joseph Ritter. His laboratory’s research was focused on a major family of phase II enzymes (UDP-glucuronosyltrasferases (UGTs) and their respective detoxification pathway. While under his guidance, Kristini worked on her dissertation research that focused on understanding the involvement of UGTs in the prevention of gastrointestinal toxicity associated with an immunosuppressant, mycophenolic acid (MPA). Her research was exciting, challenging and essential in developing her career path going forward. She aspired to incorporate her educational training into a broader, corporate environment and become involved in the area of risk assessment.
In 2006, Kristini accepted a position with Kraft Foods and worked in the Scientific and Regulatory Affairs division, where she supported food safety on a global basis. Under the guidance of Dr. Daniel Skrypec, she conducted safety assessments for food ingredients and novel technologies. This experience allowed her to obtain a position with Kimberly-Clark Corporation in 2008 where she is currently employed. In her current role, Kristini supports innovative product development and Kimberly-Clark’s global businesses by evaluating the safety of surface sanitizers, disinfectants and non-woven consumer products.
Kristini continues to play an active role in the CDI program by volunteering as a host mentor. In addition, she is the 2010–2011 Secretary/Treasurer of the Toxicologists of African Origin (TAO) Special Interest Group. She believes in the mission of CDI’s program and encourages her colleagues and peers to become involved in ensuring the long-term success of this program.
|Undergraduate Education Program for Minority Students Honoree: 1997
Current Position: Scientist, Department of Protein Chemistry, Genentech
1998: BS in Biochemistry, University of Oklahoma
2003: PhD University of Arizona
2003–2007: Postdoctoral Fellowship, Harvard University
Because I was interested in understanding how drug toxicity and environmental chemicals damaged cells and tissues, I chose to pursue a PhD degree in the area of Pharmacology and Toxicology at the University of Arizona. During my graduate studies I continued my involvement in the SOT Undergraduate Program. Professor Jay Gandolfi was my research mentor and my dissertation focused on characterizing the effects of low level arsenic insults on the ubiquitin-proteasome pathway. The final part of this work was to develop cutting edge mass spectrometry tools, a decision which has dramatically altered my career path. After receiving my PhD in 2003, I moved to Harvard Medical School for a postdoctoral fellowship in Professor Steven Gygi’s lab. During this exciting period, the ubiquitin and mass spectrometry fields began to explode scientifically. I worked to develop quantitative tools for studying differences between normal and diseases cells and received the opportunity to speak at a number of international scientific meetings.
With this experience I was able to secure a position as Scientist in the Department of Protein Chemistry at Genentech in 2007. My group employs mass spectrometry to help understand the mechanisms of action for therapeutic agents and identify new drug targets. We believe that disruption of ubiquitin system is an underlying cause of diseases as diverse as cancer, neurodegeneration, and immune dysfunction and continue to investigate this pathway in contributing to Genentech’s goal of serving patients with unmet medical needs.
|Undergraduate Education Program for Minority Students Honoree: 2000
Current Position: Scientist, Discovery Toxicology, Amgen, Inc.
2002: BS in Microbiology, University of Texas at Austin
2007: PhD in Molecular Biology and Biochemistry, University of Louisville
2007–2008: Postdoctoral Fellowship, University of Texas MD Anderson
I continued to participate as a UEP peer mentor from 2001–2008 and met my graduate mentor, Dr. Kenneth Ramos, during the recruiting session at the 2001 SOT in San Francisco, CA. My graduate work focused on determining the molecular mechanism by which the Aryl Hydrocarbon Receptor and Wilms’ Tumor transcription factor govern ontogenesis as regulated by somatic and environmental factors in utero. I continued my molecular toxicology training in the laboratory of Dr. Cheryl Walker as a postdoc at the University of Texas MD Anderson examining the involvement of the mammalian Target of Rapamycin (mTOR) signaling cascade in carcinogenesis and autophagy.
My diverse research experience prepared me for my current position as a Scientist in the Discovery Toxicology group at Amgen, Inc. Our group coordinates the integration of proactive safety assessments and works with internal and external groups to address potential safety concerns.
In 2008, I was nominated CDI Chair thus allowing me to give back to the program that changed my life setting me on my path as a toxicologist. Through the leadership of those before me and those to come, the CDI will continue to nurture the careers of budding toxicologists and will continue to strengthen and diversify the pipeline of young talent to the field of toxicology.
|Undergraduate Education Program for Minority Students Honoree: 1998
Current Position: Assistant Dean for Graduate Education, Stanford University School of Medicine
BS in Chemistry, Mary Baldwin College, Program for the Exceptionally Gifted
MS in Toxicology, University of Rochester
PhD in Toxicology, University of Rochester
Associate Scientist, Genentech, Inc.
Research Scientist, Gilead Sciences, Inc.
During her sophomore year of college, at age 15, Tenea Watson decided upon Chemistry major. Through the recommendation of her advisor, Dr. Elizabeth Hairfield, Tenea applied to several summer internships and was accepted to work in a molecular biology laboratory under the tutelage of Janet DiPasquale at the U.S. Department of Agriculture (USDA). After two summers at the USDA determining the genetic similarities between viral isolates from cucumber plants, Tenea recognized graduate school as the next step to achieve her educational and professional goals. Tenea decided to pursue a PhD in Toxicology after Dr. Hairfield gave her the SOT book The Resource Guide to Careers in Toxicology (now online). She also had candid conversations with her mother, Aremita Watson, who described her own experiences as an African American female in the sciences.
Tenea then applied to and was invited to attend the 1998 SOT-SCMI Undergraduate Education Program for Minority Students in Seattle, Washington, which confirmed her desire to pursue a PhD in toxicology. As a direct result of this program, Tenea participated in yet another summer internship in the genetic toxicology lab of Warren Ku at Pfizer, studying the induction of cytochrome P450 isoforms by candidate pharmaceuticals. A few weeks later Tenea enrolled in the Toxicology Training Program at the University of Rochester. During her time in graduate school, she studied the immunomodulatory effects of Clara Cell Secretory Protein under Drs. Barry Stripp and Jacob Finkelstein. She was able to network at the SOT Annual Meetings and meet her future manager, who offered her an associate scientist position in the Safety Assessment Department at Genentech. Tenea evaluated the safety of candidate pharmaceuticals to combat cancer and autoimmune disease while employed there. Continuing on the path of drug development, Tenea is currently a toxicologist at Gilead Sciences, in Foster City, California, where she evaluates the safety of pharmaceuticals for the treatment and management of HIV/AIDS.
During school, Tenea was regularly involved in the student recruitment efforts and in affinity groups for underrepresented minorities. At Gententech she was a co-chair of African Americans in Biotechnology. She continues to give back to the community through science education and health awareness. Dr. Nelson encourages underrepresented minorities in the sciences to find a mentor to help them navigate the nuances of higher education and careers.
Tenea has parlayed her interest in broadening diversity in the sciences into her current career as Assistant Dean for Graduate Education and Director of Biosciences Diversity Programs in the Stanford School of Medicine. In her role she develops and manages programs to recruit and retain underrepresented minorities to PhD programs in the Biosciences, such as the Stanford Summer Research Program and the Stanford Diversity Outreach for Doctoral Education Centers of Influence Retreat. She travels the country, attending research conferences and visiting individual schools, to encourage and guide undergraduates in the sciences. Tenea is a member of the Committee for Graduate Admissions and Policy and serves as a mentor for current graduate students.
|Undergraduate Education Program for Minority Students Honoree: 2001
Current Position: Toxicologist at SRC
2001: BS in Biology, BS in Environmental Science, North Carolina
2006: PhD in Environmental Sciences & Engineering, University of North Carolina at Chapel Hill
In addition to classes, Jennifer continued to work in Dr. Byrd’s laboratory and was able to present her work in poster format at the National Minority Research Symposium (NMRS) in New Orleans, Louisiana. The following Summer, Jennifer worked in Dr. Jonathan Ladapo’s laboratory (NCCU) purifying and characterizing microorganisms from a recreational lake.
She presented a poster of this work at the 1998 NMRS meeting in New York City. The summer of 1999 found Jennifer in Massachusetts in the MIT Summer Research Program. While there she worked with Dr. Leila Bradley under Dr. Hazel Sive at the Whitehead Institute for Biomedical Research to examine morphological changes in Xenopus laevis injected with Xfrb RNA and Xwnt8 RNA and DNA. That experience showed her how to combine her previous biological research with environmental science and led her to consider the effects of environmental pollutants on embryonic development. Jennifer was able to give a seminar in Cambridge and a poster presentation (NMRS, 1999) of her work.
The next summer she participated in the Summer Pre-Graduate Research Experience Program (SPGRE) at the University of North Carolina at Chapel Hill (UNC-CH) in Dr. Marc Peifer’s laboratory. There she used Drosophila melanogaster as a model to study the effects of the tumor suppressor adenomatous polyposis coli on muscle and nervous system development in embryos. Through her SPGRE mentor, Dr. LaMont Bryant, Jennifer was able to talk to faculty at UNC as well as the U.S. Environmental Protection Agency (U.S. EPA), where LaMont was conducting his doctoral research. These discussions led to Jennifer volunteering the final semester of her senior year at the U.S. EPA with Dr. Suzanne Fenton. Jennifer was selected during this time to participate in the SCMI Undergraduate Education Program for Minority Students. This program was crucial to influencing Jennifer’s goals as she entered graduate school at UNC-CH. Once again, and with permission of her graduate advisor Dr. Louise Ball, Jennifer began research the summer before starting classes. She chose to remain at the US EPA working with Dr. Fenton on examining how atrazine, a widely used herbicide, affects mammary gland development in offspring exposed during gestation. In 2002, Jennifer presented her work at the North Carolina SOT and Triangle Consortium for Reproductive Biology. She was also asked to serve as a Peer Mentor for the Undergraduate Education Program for Minority Students at the SOT Annual Meeting and gladly accepted.
Since 2002 Jennifer has served as a Peer or Host Mentor for the program and has loved being able to share her experiences with the students. She has also continued to present her work at the Annual Meeting. Through working with the program, Jennifer has made many contacts, one of whom, Charles Azuka, introduced her to the summer intern program at The Proctor & Gamble Company. She participated during the summer of 2005 and worked in the laboratory of George Daston and Jorge Naciff. The summer program, in addition to doing research using in vitro techniques, introduced her to an area of toxicological work different from what she had experienced in academia and government. Jennifer graduated in 2006 with a PhD in Environmental Sciences and Engineering. She is currently working as a toxicologist at Oak Ridge National Laboratory, Oak Ridge, TN, where she develops toxicity assessments and technical documents regarding human health risks and environmental impacts. She has several published peer-reviewed journal articles and abstracts. In 2009, Jennifer was appointed to serve on the CDI, and has aided in creating a memorable experience for undergraduate students.
|Undergraduate Education Program for Minority Students Honoree: 1993
Current Positions: Associate Professor of Biology and the Cancer Research Program, North Carolina Central University, Durham, NC and Adjunct Assistant Professor of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill
1995: BS in Biology, Norfolk State University
2001: PhD in Pharmacology and Toxicology, University of Arizona
2001–2006: Postdoctoral Fellowship, University of North Carolina at Chapel Hill
Two important events occurred at this meeting that significantly influenced Dr. Baines’ decision to work towards a scientific career. First, he was paired with Ed Sargent, an experienced toxicologist who worked for the pharmaceutical company Merck. Dr. Sargent was responsible for taking Dr. Baines “under his wing” at the conference. He demonstrated how to evaluate posters and ask the right types of questions to researchers. This was an eye-opening experience for Dr. Baines that has stayed with him even to this day. Secondly, he was awarded the opportunity to meet Dwayne Hill, one of the minority speakers of the Educational Program at SOT who spoke about his research. At this time, Dr. Hill was a senior-level graduate student at the University of Arizona (U of AZ) and worked in the laboratory of I. Glenn Sipes, a former Department Chair of Pharmacology and Toxicology and a former President of SOT. This meeting resulted in the opportunity to conduct research in toxicology for 2 summers in Dr. Sipes’ lab as an undergraduate student. These two summer research experiences led to an authorship on two publications and a research poster that Dr. Baines presented at the 1995 SOT Annual Meeting in Baltimore, MD.
In the Fall of 1995, Dr. Baines entered the graduate program in pharmacology and toxicology at the U of AZ and worked in the laboratory of Dr. Mark A. Nelson. His dissertation research focusing on the mechanism of action of the anticancer effects of selenomethionine (organic derivative of selenium) was presented at several national SOT meetings and a regional Mountain West SOT meeting.
While in graduate school, Dr. Baines participated in different capacities for SOT as a guest speaker for the Undergraduate Education program and as a peer mentor. After receiving his PhD in May 2001, becoming the second African-American to graduate with a doctorate from the Pharmacology and Toxicology graduate program at the U of AZ, Dr. Baines entered a teaching/research postdoctoral fellowship program at the University of North Carolina at Chapel Hill in the Departments of Pharmacology and Radiation Oncology.
Dr. Baines’ research focuses on trying to find novel molecular targets for potential treatments of pancreatic cancer. He continues to work with the Educational program of SOT from time to time. Dr. Baines served as a guest speaker at the 2005 SOT Annual Meeting where he discussed “Mentoring Diverse Undergraduates” with professors and administrators. His career goal is to become a faculty member at an undergraduate institution where he can teach and get students involved and excited about cancer research.
After finishing his postdoc in the summer 2006, Dr. Baines accepted a tenure-track faculty position in the Department of Biology and the Cancer Research Program at North Carolina Central University in Durham, North Carolina. As a junior faculty member, he splits his time between teaching classes such as Graduate Toxicology and mentoring students in his cancer biology research laboratory. The focus of Dr. Baines’ research lab is to identify and validate novel molecular targets in pancreatic cancer which potentially could be targeted by therapeutics. In addition, he is an adjunct faculty member in the Department of Pharmacology at the University of North Carolina at Chapel Hill. Along with helping to discover better treatments against pancreatic cancer, Dr. Baines works to improve the lack of diversity in the sciences and has continued his involvement in the SOT Undergraduate Education Program.
|Undergraduate Education Program for Minority Students Honoree: 1995
Eye on SCMI Success
Current Position: Toxicologist at Procter and Gamble
1996: BS, Pharmacy, University of Puerto Rico School of Pharmacy
2002: PhD, Pharmacology and Toxicology, University of Connecticut
2002–2004: Postdoctorate Position, University of Rochester
2004: Procter and Gamble
While obtaining her BS in Pharmacy at the University of Puerto Rico School of Pharmacy, Dr. Silva knew that she wanted to attend graduate school. In order to strengthen her graduate application, she understood that research experience was necessary. In 1994, she joined Braulio Jiménez-Velez’s toxicology laboratory at the University of Puerto Rico, School of Pharmacy. Dr. Jiménez-Velez quickly noticed Dr. Silva’s potential as a scientist and encouraged her to apply for research internships and awards. In 1995 Dr. Silva had the honor of being selected to participate in the 1995 SOT-SCMI Undergraduate Education Program for Minority Students Program in Baltimore, Maryland. This program turned out to be a crucial experience in Dr. Silva’s professional career as it was there that she met her PhD advisor, José Manautou and discovered the many opportunities that toxicology has to offer. After working in Dr. Manautou’s laboratory at the University of Connecticut that summer, she was able to write her first abstract for the 1996 SOT in Anaheim, California and subsequently joined the University of Connecticut Graduate Program in 1997. From 1998–2002, she wrote other abstracts focusing on her graduate research: the effects of organic anion in acetaminophen hepatotoxicity. While in graduate school, Dr. Silva took on a different role within the SCMI Program by participating as a peer mentor to other minority undergraduates selected under the same Program she once attended. After receiving her PhD in October 2002, she started her postdoctoral appointment in November 2002, and in July 2003, she received a US EPA pilot project grant to conduct studies on the effects of ultrafine particles in the cardiovascular system. Through these years she continued to participate as a peer mentor and subsequently as a host or well-established toxicologist. As a peer mentor and host in this program, she has been able to encourage many other minorities like herself to pursue graduate studies. In addition, Dr. Silva adds a unique perspective as she is able to share her own personal experiences as an undergraduate student honoree of SCMI, a graduate student and peer mentor of SCMI, and as a newly established toxicologist in the consumer product industry. In her position she is in charge of assessing the safety of raw ingredients in feminine hygiene products as well as safety for new products.