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Thank you for attending the SOT Annual Meeting March 11–15, 2012!

Mark your calendar SOT Annual Meeting March 10–14, 2013.

Toxicology Terms

Toxicology Enrichment Materials

Bioaccumulate

The increased concentration of harmful substances in tissues of organisms higher up the food chain

Biotransformation

The sum of the processes by which a xenobiotic is subjected to chemical change by living organisms

Carcinogen

Any substance that causes cancer

Mutagen

Any substance that causes DNA damage, ranging from changes in one or a few base pairs to gross changes in chromosome structure or number

Pollutant

A substance present in greater than natural concentration as a result of human activity and having a net detrimental effect on its environment

Risk

Probability a substance will cause harm under specific conditions of use, i.e., hazard

Teratogen

Any substance that causes fetal malformations (birth defects)

Toxic substance (regulatory term)

Any substance that can cause acute or chronic injury to the human body or is suspected to do so; US National Institute of Occupational Safety and Health publishes a list of toxic substances

Toxicant

Any agent capable of producing a deleterious response in a biological system

Toxicologist

A scientist specially trained to examine the nature of these adverse effects and to assess the probability of their occurrence

Toxicology

The study of the adverse effects of chemicals on living organisms

Toxicosis

A diseased condition resulting from poisoning

Toxigenic

An organism producing toxins or poisons

Toxin

A poisonous substance of natural origin (plant, animal, bacterial, fungal)

Toxoid

A toxin that has been treated to destroy its toxicity

Xenobiotic

Compounds exogenous (external) to normal metabolism of the organism, i.e., foreign compounds

 

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