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Satellite Meetings

Each year, SOT endorses several Satellite Meetings that are held in conjunction with the Annual Meeting. Satellite Meetings are organized around scientific topics related to toxicology and are scheduled at the end of the Society’s program. The 2016 Satellite Meetings will be held in and around the New Orleans area.

Updates on Activities Related to 21st Century Toxicology and Related Efforts: Invited Presentations and Open Microphone

Thursday, March 17, 12:30 PM–4:00 PM

Hilton New Orleans Riverside, Jefferson Ballroom

Hosted by: Thomas Hartung, Johns Hopkins Center for Alternatives to Animal Testing (CAAT), Baltimore, MD.

If you’re planning to attend the Society of Toxicology conference in New Orleans this March, please join the Center for Alternatives to Animal Testing (CAAT), the Human Toxicology Project Consortium (HTPC), and the Human Toxome Project Consortium for our annual satellite meeting on 21st century toxicology activities and related efforts. The satellite meeting provides an informal setting in which interested stakeholders can update each other on these important topics.

The meeting will feature a number of invited presentations but also leave time for an “open microphone” segment in which participants are welcome to give brief presentations on germane topics, with or without a few slides.

The draft program is as follows:

12:30 PM—Box Lunch (for pre-registered participants) and Welcome. Thomas Hartung, Johns Hopkins University

1:00 PM—Invited Speakers (10 minute presentations each followed by 5 minute of discussion)

  • ToxCast Update. Russell Thomas, US Environmental Protection Agency
  • EDSP21 Update. David Dix, US Environmental Protection Agency
  • Tox21 Update. Richard Paules, US National Toxicology Program
  • Hamner TT21C Update. Melvin Andersen, Hamner Institutes
  • NICEATM Update. Warren Casey, NICEATM
  • SEURAT/EU Tox-Risk Update. Michael Schwarz, University of Tuebingen
  • CAAT’s Read-Across Initiative and Human Toxome-Related Activity Update. Thomas Hartung, Johns Hopkins
  • Human Toxicology Project Consortium Update. Catherine Willett, HTPC
  • Evidence-Based Toxicology Update. Martin Stephens, Johns Hopkins

3:15 PM—Open Microphone for Additional Presentations and Discussio

4:00 PM—Adjourn

Please register by email at your earliest convenience with Jamie DeRita. Box lunches will be available to those who have pre-registered.

3D or Not 3D: That Is the [Predictive Toxicology] Question…

Thursday, March 17, 1:00 PM–5:00 PM

Room 213

Hosted by: Elaine Faustman, University of Washington, Seattle, WA; and Barbara Klieforth, US Environmental Protection Agency, Washington, DC.

Purpose of the Meeting: How complex must cell cultures be to replicate the dynamics of tissue interactions and functions in order to be predictive of in vivo responses? We will discuss the latest successes and challenges in differing organotypic and three-dimensional cell culture systems. The US EPA’s Chemical Safety for Sustainability program provided Science to Achieve Results (STAR) research grants to develop and evaluate medium to high throughput toxicity screening systems in order to assess chemicals. Their work, on tissue systems including the brain, liver, kidney, testis, breast tissue, heart and neurovascular systems, is intended to complement ongoing US EPA research and lead to refined models of how organs and tissues respond to environmental chemicals. Researchers from the four US EPA STAR grant Centers and from US EPA’s Office of Research and Development will present their work.

12:00 PM Poster set up and display
1:00 PM–1:10 PM Welcome
Tom Knudsen, US EPA Chemical Safety for Sustainability National Program
1:10 PM–1:30 PM Human Pluripotent Stem Cell Models for Predicting Neural Toxicity
Jamie Thomson, The Morgridge Institute for Research
1:30 PM–1:50 PM “Ready, Seed, Perfuse”: Application and Challenges to Constructing a Competent Human Liver on a Chip
Lawrence Vernetti, Vanderbilt University
1:50 PM–2:10 PM Rebuilding the Whole From the Parts: A Case Study of the Kidney
Ed Kelly, University of Washington
2:10 PM–2:30 PM EPA Virtual Tissue Models
Sid Hunter, EPA Chemical Safety for Sustainability National Program
2:30 PM–3:00 PM Break
3:00 PM–3:20 PM “It’s Not 3D, but It’s Alive!” Studies of Cardiac Physiology in Cell Culture
Ivan Rusyn, Texas A&M University’s Center Cardiotoxicity Adverse Outcome Pathway
3:20 PM–3:40 PM
Building the Microenvironment into In Vitro Models of Cancer
David Beebe, University of Wisconsin, Madison
4:00 PM–5:00 PM POSTER SESSION—Posters of EPA/ORD and STAR Organotypic Culture Model Centers research
5:00 PM–8:00 PM CLOSED SESSION & Dinner with STAR OCM Centers Investigators and EPA

Agenda PDF icon

Registration: Open registration. No fee to register and attend.

Lectures followed by Q&A and a poster session.

For more information on this Satellite Meeting, contact Barbara Klieforth.

A Toxicology User’s Guide to the Roadmap Epigenomics and ENCODE Data Resources

Thursday, March 17, 1:00 PM–6:00 PM

Room 205

Hosted by: Ivan Rusyn, Texas A&M University, College Station, TX; and Lisa Chadwick, NIEHS, Research Triangle Park, NC.

Purpose of the Meeting: Improvements in DNA sequencing technologies have resulted in an exponential increase in the amount of genomic and epigenomic data available. Some of these data have been generated as part of large-scale, focused mapping efforts aimed at understanding how genes are regulated, such as the NIH Roadmap Epigenomics Program, and ENCODE (Encyclopedia of DNA Elements). Efforts such as these can be extremely valuable for hypothesis generation and data mining, but can only be useful if one knows what is available and how to use it. This SOT satellite meeting will provide toxicology researchers with an overview of these two NIH-funded programs, introduce attendees to the informatics tools that have been developed to help navigate these large datasets, and walk through several use cases. The meeting will be of broad interest to researchers interested in learning more about how environmental exposure might impact gene regulation.

Registration: Open registration. No fee to register and attend.

Lectures followed by Q&A and a poster session.

For more information on this Satellite Meeting, contact Lisa Chadwick.