Program Overview

This page is meant to provide a quick glimpse at the schedule of sessions and events which will occur during the 2019 SOT Annual Meeting and ToxExpo. As information becomes available and activities are finalized, they will be added to this page. Full details and information on the sessions and events listed on this page are available on the Program Details page.

Key:  

90 90-minute sessions  IAT Innovations in Applied Toxicology  ITS Innovations in Toxicological Sciences

  

Saturday, March 9

5:00 PM to 7:30 PM

Undergraduate Diversity Program


7:30 PM to 8:30 PM

Committee on Diversity Initiatives (CDI) Reunion


Sunday, March 10

7:00 AM to 7:45 AM

Continuing Education Sunrise Mini-Courses

  • SR01: Handling Uncertainties in Evaluating Mixtures: What’s the Difference between a “Similar” and a “Sufficiently Similar” Mixture?
  • SR02: Publicly Available Exposure Tools to Inform the Toxic Substances Control Act

8:00 AM to 5:00 PM

Undergraduate Diversity Program

Undergraduate Education Program


8:15 AM to 12:00 Noon

Continuing Education Morning Courses

  • AM03: Assay Development Principles and Good Research Practices for Rigor and Reproducibility in In Vitro Toxicology
  • AM04: Complex Mixtures and UVCBs: Analysis, Testing, and Risk Assessment
  • AM05: Developmental Toxicity of the Skeletal System: Interpretation of Findings in DART Studies and Implications for Risk Assessment
  • AM06: Industrial Application of Computational Toxicology in the 21st Century
  • AM07: Role of Toxicokinetics in Human Health Safety Assessments
  • AM08: Mechanistic Understanding and Quantitative Risk Assessment in Immunotoxicology

1:15 PM to 5:00 PM

Continuing Education Afternoon Courses

  • PM09: Applications and Review of Physiologically-Based Pharmacokinetic Modeling for Regulatory Risk Assessment
  • PM10: Beauty of the Skin Is in the Eye of the Beholder: A Basic Course on Dermal and Ocular Toxicology
  • PM11: Conducting Systematic Review in Toxicology—Why, When, How?
  • PM12: Current Dose-Response Modeling Strategies and Applications in Chemical Risk Assessment
  • PM13: Microbiome and Environmental Toxicants: From Study Design and Analysis to Regulatory Guidance
  • PM14: Structural and Functional Alterations of Mitochondria in Chemically-Induced Cytotoxicity

4:45 PM to 5:15 PM

Awards Ceremony Music


5:15 PM to 6:30 PM

Awards Ceremony


6:30 PM to 7:30 PM

Welcome Reception


7:00 PM to 8:00 PM

25-Year (Or More) Member Reception


7:30 PM to 9:00 PM

Student/Postdoctoral Scholar Mixer


Monday, March 11

6:15 AM to 7:45 AM

SOT Mentoring Breakfast


6:30 AM to 8:00 AM

Past Presidents’ Breakfast


6:30 AM to 8:30 AM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Leadership Breakfast Meetings


7:30 AM to 5:30 PM

Undergraduate Diversity Program


8:00 AM to 9:00 AM

Opening Plenary Session

Robust Assembly of Human Tissues for Disease Modeling and Discovery
Lecturer: William L. Murphy, University of Wisconsin-Madison, Madison, WI.

Dr. Murphy will enlighten us on his interdisciplinary approaches to develop innovative biomaterials, or as he describes, ‘bioinspired materials,’ because they mimic the fascinating ways that nature builds materials—including human organs. Such materials are quickly being adopted by toxicologists to bridge the gap between alternative methods that rely on molecular- and cellular-based platforms and whole organs or organisms. His lecture promises to be of particular interest to anyone interested in the development of new alternative methods and how these methods can be used to fulfill the vision of toxicity testing in the 21st century.”

— Ron Hines
Chair, Scientific Program Committee


9:00 AM to 5:30 PM

Exhibitor-Hosted Sessions


9:15 AM to 12:00 Noon

Symposium Sessions

  • Advances in In Vitro to In Vivo Extrapolation: Approaches and Applications
  • Alpha-Synuclein: A Good Protein Turned Bad in Chronic Brain Diseases with Toxicological Implications
  • Assessing Acute Health Risk: Potential Application of Next-Generation Toxicological Tools
  • Novel Genetic-Based Tools for Evaluating Toxicity Potential, Mechanism of Action, and Population Dynamics

Workshop Sessions

  • Application of Computational Modeling to Risk Assessment of Endocrine Disruptors
  • MALDI Tissue Imaging: A New Tool for Making TK/TD Connections to Histopathology
  • Mechanisms and Effects of Diabetogenic Environmental Metals: Type II Diabetes Mellitus and Diabetic Kidney Disease
  • Pharmaceutical Investigative Toxicology: Case Studies in Optimizing Drug Discovery and Guiding Human Risk Assessment

9:15 AM to 4:30 PM

Poster Sessions

ToxExpo Exhibits


9:30 AM to 11:30 AM

IUTOX Global Collaboration Coffee


9:30 AM to 3:00 PM

Research Funding Insights: Network with Grant Program Officers


9:45 AM to 10:45 AM

Trainee Discussion with Plenary Session Presenter: Dr. Murphy


11:45 AM to 12:15 PM

Global Gallery of Toxicology—Representative Attended

Toxicology societies from around the world are invited to develop and display a poster in the Global Gallery that showcases the organization, upcoming meetings, strategic activities, and accomplishments of their organization. On display during ToxExpo hours, the Global Gallery gives attendees the opportunity to gain insights on the global aspects of toxicology. The posters will be attended by group representatives on Monday, March 11, from 11:45 am to 12:15 pm.

Global Gallery of Toxicology Posters

Upload your poster to the virtual gallery, which will display below. (Please allow up to 24 hours for the poster to display.)


Regional Chapter, Special Interest Group, and Specialty Section Poster Sessions—Representative Attended

On display during ToxExpo hours, the SOT Regional Chapter, Special Interest Group, and Specialty Section posters share information about the activities and opportunities associated with membership to these SOT groups. The posters will be attended by group representatives on Monday, March 11, from 11:45 am to 12:15 pm.

Virtual Regional Chapter, Special Interest Group, and Specialty Section Posters

Upload your poster to the virtual gallery, which will display below. (Please allow up to 24 hours for the poster to display.)


12:00 Noon to 1:30 PM

In Vitro Toxicology Lecture and Luncheon for Students: Patient-Based Cellular Model Systems to Assess Individual Risk to Neurotoxicants


12:00 Noon to 2:00 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Lunch Networking Events


12:10 PM to 1:30 PM

Roundtable Session

  • Data for Chemical Evaluations: Secret or Otherwise

Informational Sessions

  • Electronic Waste: An Evolving Global Health Concern and Risk Assessment Challenge
  • Federal Efforts in Rapidly Assessing Hazard and Risk to Emerging Threats and Emergency Response

12:30 PM to 1:30 PM

Distinguished Toxicology Scholar Award Lecture

Lecturer: Cheryl Lyn Walker, Baylor College of Medicine, Center for Precision Environmental Health, Houston, TX


1:45 PM to 4:30 PM

Symposium Sessions

  • Immune-Epithelial Cell Cross Talk in Lung Toxicology and Disease
  • Patterns of Co-Exposure and Its Implications for Understanding the Health Effects of Mixtures
  • Scaling Barriers: Cellular Dynamics and Models of Blood-Brain Barrier Developmental Toxicity ITS
  • Strategic Development of Read-Across within the EU-ToxRisk Project and Beyond

Workshop Sessions

  • A Herculean Switch? Rethinking Chemical Carcinogenicity Assessment
  • A Tale of an In Vitro Method: From Inception to International and Regulatory Acceptance
  • Applying Systems Biology Approaches to Understand the Joint Action of Chemical and Nonchemical Stressors
  • NextGen Renal Proximal Tubule Toxicity Screening: Novel Cellular Model and Complex Culture Platforms IAT

3:00 PM to 4:30 PM

Research Funding Insights Session: Funding 101: Multiple Perspectives on the NIH Grant Process


4:30 PM to 5:50 PM

Education-Career Development Session

  • Models and Strategies for Building Diversity and Inclusion in Toxicology

4:45 PM to 6:00 PM

SOT/EUROTOX Debate

Classification of Substances as Endocrine Disruptors Has a Public Health Benefit
Debaters: Paul Foster, NIEHS (Retired), Research Triangle Park, NC; and Martin Van den Berg, Utrecht University, Utrecht, Netherlands.


4:45 PM to 9:30 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Group Receptions


Tuesday, March 12

7:00 AM to 8:00 AM


8:00 AM to 10:45 AM

SOCIETY OF TOXICOLOGY AND JAPANESE SOCIETY OF TOXICOLOGY SYMPOSIUM

Epigenetic Modification of Chronic Pathology and Toxicology
Lecturers: Masatoshi Hagiwara, Kyoto University, Kyoto, Japan; Jun Kanno, Japan Bioassay Research Center, Kanagawa, Japan; Dana Dolinoy, University of Michigan School of Public Health, Ann Arbor, MI; and Cheryl Lyn Walker, Baylor College of Medicine, Center for Precision Environmental Health, Houston, TX.

Symposium Sessions

  • “Not Your Father’s ED”: Expanding the Definition and Understanding of Endothelial Dysfunction (ED) Due to Inhaled Toxicants
  • Stem Cells and Metals Toxicity: From Tissue Regeneration and Repair to Carcinogenesis
  • Systems Toxicology Approaches to the Science of Safety Evaluation
  • Using Zebrafish as a Model to Understand and Ultimately Prevent Neurotoxicity

Workshop Sessions

  • Emergent Mechanisms of Cytochrome P450 Gene Regulation: Defining an Improved Roadmap towards 21st Century Pharmacogenomics
  • Predicting Metabolic Clearance Rates for Drug Leads and Environmental Chemical Risk Assessment
  • Shifting Currents in Predictive Toxicology and Safety Evaluation with In Vitro and Alternative Approaches
  • Strategies to Mitigate the Health Impacts of Air Pollutants in Susceptible Populations

9:00 AM to 5:30 PM

Exhibitor-Hosted Sessions


9:15 AM to 4:30 PM

Poster Sessions

ToxExpo Exhibits


9:30 AM to 4:30 PM

Research Funding Insights: Network with Grant Program Officers


11:00 AM to 12:00 Noon

Meet the Directors

Linda S. Birnbaum, Jennifer Orme-Zavaleta, and Mark S. Johnson
Panelists: Linda S. Birnbaum, NIEHS, Research Triangle Park, NC; Jennifer Orme-Zavaleta, US EPA, Research Triangle Park, NC; and Mark S. Johnson, Army Public Health Center, Aberdeen Proving Ground, MD.

Meet the Directors

Translational Impact Award Lecture

Lecturer: Harmut Jaeschke, University of Kansas Medical Center, Kansas City, KS.


11:00 AM to 12:20 PM

Roundtable Session

  • The Delaney Clause, from 1958 to 2019: Making the Model Relevant

Informational Sessions

  • Challenges and Opportunities Encountered with TSCA Reform: Working toward a Shared Vision for Product Safety
  • Science at the Nexus of Wildfire Smoke and Public Health

11:30 AM to 2:00 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Lunch Networking Events


12:00 Noon to 1:00 PM

Postdoctoral Assembly Luncheon


12:30 PM to 1:30 PM

Merit Award Lecture

Lecturer: Stephen H. Safe, Texas A&M University, College Station, TX.


1:00 PM to 2:30 PM

Toxicological Sciences Featured Session

From the Pages of ToxSci: Mouse vs. Machine … Are Animal Studies Being Supplanted by Computers?
Panelists: Gary W. Miller, Columbia University, New York, NY; Alison Harrill, NIEHS/NTP, Research Triangle Park, NC; Thomas Hartung, Johns Hopkins University Center for Alternatives to Animal Testing (CAAT), Baltimore, MD; Nicole Kleinstreuer, NIEHS, Research Triangle Park, NC; and Ivan Rusyn, Texas A&M University, College Station, TX.

Symposium Sessions 90

  • Explicating the Pathogenic Environmental Factors in Nonalcoholic Fatty Liver Disease
  • Integrated ‘Omics Approaches to Toxicity Assessments
  • Scientific and Regulatory Update in the Application of the 3Rs Principle in Chemical and Drug Development

Workshop Sessions 90

  • Adverse or Not-Adverse?: Thinking Process behind Adversity Determination during Nonclinical Drug Development
  • Assessing the Bisphenol Class of Chemicals
  • In Vitro Static and Dynamic Skin Metabolism Methods and Strategies to Address the Safety Assessment of Topically-Applied Chemicals
  • Innovation in Biomarker Qualification

1:00 PM to 2:30 PM

Hot Topic Featured Session

Proposal submission period begins in December 2018


1:30 PM to 2:50 PM

Career Exploration through Speed Informational Interviews


2:30 PM to 3:00 PM

Networking Time


3:00 PM to 4:30 PM

Symposium Sessions 90

  • Microbiota and Contributions to Neurodevelopment: Implications in Neurological Function, Behavior, and Toxicity
  • Novel Safety Biomarker Qualification: Updates and Progress
  • Perfluoroalkyl Substances (PFAS): Global and Persistent Environmental Contaminants
  • Species Relevance: Approaches to Determine the Most Relevant Species for Safety Assessment of Pharmaceutical Products
  • The Current Application, Limitations, and Recent Advances in Humanized Mouse Models for Evaluations of Immune Function and Preclinical Immunotoxicology Studies
  • When “Natural” Is Not Synonymous with “Safe”: Toxicity of Natural Products Alone and in Combination with Pharmaceutical Agents

Workshop Sessions 90

  • New Approaches Using Mode-of-Action to Predict Acute and Systemic Toxicity IAT
  • The Utility of Echocardiography in Cardiac Safety Assessment

4:45 PM to 6:05 PM

Education-Career Development Session

  • Tips for Improving Scientific Communication with a General Audience

4:45 PM to 6:15 PM

SOT Annual Business Meeting


6:00 PM to 10:00 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Group Receptions


7:30 PM to 9:00 PM

Tox ShowDown


Wednesday, March 13

6:30 AM to 8:00 AM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Leadership Breakfast Meetings


8:00 AM to 10:45 AM

Symposium Sessions

  • Establishing Effective Alternatives for Acute Oral and Inhalation Systemic Toxicity Testing
  • Progress toward Charting the Course for Improving Carcinogenicity Assessments of Human Pharmaceuticals and Pesticides
  • The Role of Dynamic RNA Modifications in Environmental Response and Disease ITS

Workshop Sessions

  • A Sharp Stick in the Eye: Understanding and Managing Ocular Findings in General Toxicology Studies
  • Can We Panelize Seizure? IAT
  • Nerve Agent Poisoning: Mechanisms of Toxicity, Recent Releases, Verification, and Innovative Treatment Approaches
  • Pregnant and Vaping: Knowns and Unknowns of Reproductive and Developmental Toxicity Related to Electronic Cigarettes
  • Understanding the Impact on the Immune System of Occupationally-Relevant Exposures to Multiwalled Carbon Nanotubes

9:00 AM to 5:30 PM

Exhibitor-Hosted Sessions


9:15 AM to 4:30 PM

Poster Sessions

ToxExpo Exhibits


9:30 AM to 4:30 PM

Research Funding Insights: Network with Grant Program Officers


11:00 AM to 12:20 PM

Roundtable Session

  • The Necessity of Uncertainty: Quantifying Uncertainty for Regulatory Application of New Approach Methodologies

Informational Session

  • Toxicology Education and Risk Assessment Training in Africa: Status, Challenges, and Role of SOT Special Interest Groups in Moving Forward

Education-Career Development Session

  • Stepping Out of the Lab: Maximizing Access and Experience for Internships in Toxicology

11:00 AM to 12:00 Noon

EUROTOX Bo Holmstedt Memorial Award Lecture

Metabolism, Inflammation, and Cancer
Lecturer: Nigel Gooderham, Imperial College London, London, United Kingdom.

Professor Gooderham was selected as the Bo Holmstedt Memorial Lecturer from a strong field of European toxicologists. With interests in mechanisms of chemical carcinogenesis and molecular and cellular responses to toxicity, his presentation describes the role of microRNAs in colon carcinogenesis.”

— Heather Wallace
EUROTOX President 2018–2020


12:00 Noon to 1:30 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Lunch Networking Events


12:30 PM to 1:30 PM

Plenary Keynote Medical Research Council (MRC) Lecture

Ageing and Multimorbidity: Time for a New Approach
Lecturer: Janet M. Lord, University of Birmingham Institute of Inflammation and Ageing, Birmingham, United Kingdom.

Professor Janet Lord will tell us about the many factors that make aging unpleasant, and a few that are important in lessening the impact of age. This talk will be especially important to those of us who are interested in the interplay of factors that contribute to chronic diseases with environmental etiologies.”

— George P. Daston
Co-Chair, Scientific Program Committee


1:30 PM to 4:15 PM

Symposium Sessions

  • Consideration for Safety Assessment of Chemically Synthesized Therapeutic Peptides: A Drug Development Paradigm between the Large and Small
  • Role of Oxidative Stress in Health and Disease: Mechanisms, Methods of Detection, and Biomarkers
  • Understanding the Utility of In Vitro Developmental Toxicity Assays and Building Integrated Testing Strategies

Workshop Sessions

  • Air Pollution-Induced Cardiovascular Toxicity: Endothelial Progenitor Cells as Critical Mediators
  • Microphysiological Systems: A New Era in Neurotoxicology?
  • Order from Chaos: Pattern Recognition in Challenging Human Health Datasets
  • Risk Assessment of Consumer Products and Articles: Critical Considerations and Case Studies for Characterizing and Quantifying Consumer-Relevant Exposures to Chemicals and Nanomaterials
  • This Is Your Teen Brain on Drugs: In Search of Biomarkers Unique to Dependence Toxicity in Adolescents IAT

2:00 PM to 3:00 PM

Trainee Discussion with Medical Research Council (MRC) Lecturer: Dr. Lord


4:30 PM to 5:30 PM

Leading Edge in Basic Science Award Lecture

Lecturer: Sven E. Jordt, Duke University Medical Center, Durham, NC.


4:30 PM to 5:50 PM

Roundtable Session

  • A Multi-Stakeholder Dialogue on Using Proprietary Modeling Platforms to Support Risk Assessment and Regulatory Decisions

Education-Career Development Session

  • Navigating Turbulent Waters: How to Address Conflict throughout Your Career

4:15 PM to 7:30 PM (Start and End Times Vary by Event)

Regional Chapter, Special Interest Group, and Specialty Section Group Receptions


Thursday, March 14

7:00 AM to 8:00 AM

SOT Strategic Plan Update


8:30 AM to 11:15 AM

Symposium Sessions

  • Nerve Agent and Pesticide Poisoning: Best Practice Methodologies for Assessing Long-Term Health Effects
  • New Mechanistic Insights into Causes and Outcomes of Epigenetic Dysregulation by Carcinogenic Metals
  • Preconception Exposure to Toxicants: Assessing Gamete Quality and Reproductive Outcomes

Workshop Sessions

  • Potential Alternatives to Systematic Review: Evidence Maps and Scoping Reviews
  • Use of Adverse Outcome Pathways to Design Nonanimal Testing Strategies for Assessing Inhalation Toxicity

8:30 AM to 11:30 AM

Late-Breaking Poster Session

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