Events

A Machine Learning Model for PFAS Toxicokinetic Half-Lives: Enhancing Machine Learning with Biologically-Relevant Descriptors

Hosted by: The SOT Biological Modeling Specialty Section

Speaker:
John Wambaugh, PhD, Research Physical Scientist, US EPA

Materials:
Webinar Recording
Presentation

Generic Pharmacokinetic Models for Mother-to-Offspring Transfer of Chemicals

Hosted by: SOT Risk Assessment Specialty Section and Biological Modeling Specialty Section

Speaker:
Dustin F. Kapraun, PhD, US EPA

Materials:
Webinar Recording
Presentation

Improving Best Practices in Mathematical Modeling

Speaker:
Herbert Sauro, PhD
Professor and Director of Center of Reproducibility
University of Washington, Department of Bioengineering
Seattle, WA

Materials:
Webinar Recording
Presentation

Standardization of PBPK Modeling Practice

Speaker(s):
Cecilia Tan, PhD, US EPA
Paul Schlosser, PhD, US EPA

Materials:
Webinar Recording
Dr. Tan’s Presentation
Dr. Schlosser’s Presentation

Opportunities and Challenges Related to Saturation of Toxicokinetic (TK) Processes: Implications for Risk Assessment

Speaker(s):
Michelle Embry, PhD

Materials:
Webinar Recording
Presentation

Assessing the Impact of Multi-route Co-exposures on Human Variability in Toxicokinetics of Drinking Water Contaminants in Binary and Quaternary Mixtures

Speaker(s):
Mathieu Valcke, PhD
Sami Haddad, PhD

Materials:
Webinar Recording
Presentation

Mathematical models and COVID-19

Speaker(s):
Dr. Ben Lopman

Materials:
Webinar Recording
BMSS Business and Reception
COVID-19 transmission Abstract

Comparison of Various Approaches to AOP Quantification

Speaker(s):
F. Y. Bois
W. Gao
D. Reddyhoff

Materials:
Webinar Recording
Presentation

Migration of AcsIX Model Code to Magnolia

Speaker(s):
Conrad Housand

Materials:
Webinar Recording
Presentation

In Vitro to In Vivo Extrapolation (IVIVE) to Support New Approach Methodologies (NAMs)-based Safety Assessment: A Tiered Approach with a Focus on the Consideration of Kinetics and Metabolism

Speaker(s):
Miyoung Yoon

Materials:
Webinar Recording
Presentation

Quantitative Systems Toxicology as a Tool for Explaining and Predicting Drug-Related Organ Toxicity

Materials:
Webinar Recording (Unavailable)
Presentation

A Liver-centric Multiscale Modeling Framework for Xenobiotics

Speaker(s):
James P. Sluka
Xiao Fu
Maciek Swat
Julio M. Belmonte
Alin Cosmanescu
Sherry Clendenon
John F. Wambaugh
James A. Glazer

Materials:
Webinar Recording (Unavailable)
Presentation

An introduction to PK-Sim: the open source platform for PBPK

Speaker(s):
Andrea Edginton

Materials:
Presentation

There was no recording for this Webinar.

TRA Vitro—Vivo

Speaker(s):
Miyoung Yoon

Materials:
Webinar Recording (Unavailable)
Presentation

Performance Assessment and Translation of Individual or Population Physiologically Based Pharmacokinetic Models from acslX to Berkeley Madonna, MATLAB, and R language.

Speaker(s):
Zhoumeng Lin

Materials:
Webinar Recording (Unavailable)
Presentation

Application of Physiologically-Based Pharmacokinetic Modeling to Explore the Role of Kidney 2 Transporters in Renal Reabsorption of Perfluorooctanoic Acid in the Rat

Materials:
No Recording Available.
No Slides Available.

PharmML-Exchange Format for Models Used in Quantitative System Pharmacology and Pharmacometrics

Speaker(s):
Maciej J. Swat

Materials:
Webinar Recording (Unavailable)
Presentation

Saying I do to the QSAR/PBPK marriage in GastroPlus to predict chemical exposure for safety evaluation

Speaker(s):
John DiBella, MS
Fagen Zhang and Leah Luna

Materials:
Webinar Recording (Unavailable)
Presentation DiBella
Presentation Fagen Zhang and Leah Luna

Biological Modeling Webinar Series: Developing PBPK Models in MATLAB and SimBiology

Materials:
Webinar presentations and recording have been removed at the presenter’s request.

Understanding Dermal Drug Disposition Using TC`AT—A Novel PBPK Model

Materials:
Webinar Recording (Unavailable)
Presentation

PBPK Modelling

Speaker(s):
George Loizou
Drs. Paul Hinderliter and Christopher Ruark
R. Woodrow Setzer

Materials:
Webinar Recording (Unavailable)
George Loizou Presentation
Drs. Paul Hinderliter and Christopher Ruark Presentation
R. Woodrow Setzer Presentation