Welcome to the Biological Model Specialty Section (BMSS) web site. If you are not a member, please consider joining our group. The section officers and I are always happy to answer questions that you may have. For those of you who are already members, thank you for your support and for being part of this important group. The BMSS is a diverse group of people from academia, industry, and government with a passion for using quantitative, mathematical, and computational methods to solve challenging problems in toxicological safety and risk assessment. Our field is in a boom phase with high demand for new computational techniques and approaches to meet the needs of Tox21 and other forward-thinking initiatives, with challenges ranging from in vitro to in vivo extrapolation to the prediction of gene and cell perturbations associated with adverse pathways. On the drug side, PBPK and computational systems biology approaches are increasingly used in drug safety assessment and in a regulatory capacity to address issues ranging from population variability to drug-drug interactions and pediatrics. Over the last few years, BMSS has featured informative webinars on software options and applications for computational analyses. These webinars were well received, and I thank all those who volunteered to speak and those BMSS officers and members who made this happen. On behalf of the current officers and volunteers in the BMSS, who donate their time, thank you for being part of BMSS.