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Web Resources

Primary Sources

National Library of Medicine’s TOXNET

International Programme on Chemical Safety Main Search Site (IPCS)

Agency for Toxic Substances and Disease Registry (ATSDR)

European Chemical Agency Registered Substances Database (ECHA)

Screening Information Data Sets (source of old SIDS profiles)

OECD Existing Chemicals Database (source of new SIDS profiles)

Secondary Sources

Concise International Chemical Assessment Document (CICADS)

Minimal Risk Levels (MRLs)

Risk Assessment Information System (RAIS)

Chemistry Data

CDC’s ppm to mg/m3 conversion calculator


Common Chemistry (CAS numbers)

ECHA Chemical Information Database

NCI Online SMILES Translator and Structure File Generator

NIST Chemistry Web Book

OECD eChemPortal


Wolfram Alpha

Cancer Data

California Proposition 65 (CA Prop 65)

Carcinogenic Potency Database (CPDB)

International Agency for Research on Cancer Monographs (IARC)

National Toxicology Program 12th Report on Carcinogens (RoC)

Environmental & Occupational

Environmental Health Criteria Monographs (EHC)

International Chemical Safety Cards (ICSCs)

National Library of Medicine Haz-Map

NIEHS CEBS (Chemical Effects and Biological Systems)

NIOSH Pocket Guide to Chemical Hazards (NPG)

NIOSH Publications Database

NTP Health Assessment and Translation

OSHA Permissible Exposure Limits (PELs)

Registry of Toxic Effects of Chemical Substances (RTECS®) (subscription-based)

US EPA Databases

US EPA’s Integrated Risk Information System (IRIS)

US EPA’s ChemView

US EPA’s EcoTox

US EPA’s Toxicity Reference Database (ToxRefDB)

US EPA’s Toxicity Data Warehouse (ACToR)

US FDA Databases

US FDA’s List of Color Additives for Foods, Drugs, Cosmetics, and Medical Devices

US FDA’s List of Indirect Food Contact Additives

US FDA’s List of Direct Food Additives

US FDA’s Everything Added to Food in the United States (EAFUS)

US FDA’s Inactive Drug Ingredients

US FDA’s Active Drug Ingredients

US FDA’s Informatics and Computational Safety Analysis

Food & Cosmetics

WHO Joint FAO/WHO Expert Committee on Food Additives (JECFA) publications: Technical Report Series and Toxicological Monographs

Cosmetics Ingredient Review (CIR)

The Good Scents Company Information System

In Silico Prediction Tools

Analog Identification Methodology (AIM). Finds similar structures with tox data.

CAESER. Descriptor-based models that predict REACH tox endpoints.

IHCP Predictive Toxicology. Free computational tools.

OECD QSAR Toolbox. Uses structures to categorize chemicals and predict endpoints.

OncoLogic™. Predicts cancer potential of chemicals.

Tox Match. Estimates skin irritation and sensitization based on structural similarity.

Tox Predict. Estimates toxic hazard based on chemical structure.

Tox Tree. Estimates toxic hazard by applying a decision tree approach.

(All free from EPA and EU)

Lit Search

Google Scholar

National Library of Medicine’s PubMed

Pharmaceuticals & Biologics

Drug Information Portal

EBI (European Bioinformatics Institute) Database

Reproductive Toxins

California Proposition 65 (CA Prop 65)

Tox Profiles

REACH Registered Substances (free tox profiles on 11,000 chemicals)

BIBRA Toxicology Profiles ($200 each)

NSF International Profiles ($25 each)

Tox Reference Books

Merck Index

Patty’s Toxicology (often available online from corporate and university libraries)

Sax’s Dangerous Properties of Industrial Materials (often available online from corporate and university libraries)

Report of the Task Group on Reference Man (great source of chemical body burden data)

A Small Dose of Toxicology (free E-book, introduction to toxicology)

Medical Device Regulations

Worldwide medical device regulations

US FDA’s Recognized Consensus Standards

Toxicology Terms

Open Toxipedia

Other Useful Sites

The EXtension TOXicology NETwork

European Centre for Ecotoxicology and Toxicology (reports on chemicals)

US Federal Register

Federal Register (publishes notices regarding acceptable limits of chemicals)