Web Resources
Primary Sources
National Library of Medicine’s TOXNET
International Programme on Chemical Safety Main Search Site (IPCS)
Agency for Toxic Substances and Disease Registry (ATSDR)
European Chemical Agency Registered Substances Database (ECHA)
Screening Information Data Sets (source of old SIDS profiles)
OECD Existing Chemicals Database (source of new SIDS profiles)
Secondary Sources
Concise International Chemical Assessment Document (CICADS)
Minimal Risk Levels (MRLs)
Risk Assessment Information System (RAIS)
Chemistry Data
CDC’s ppm to mg/m3 conversion calculator
ChemSpider
Common Chemistry (CAS numbers)
ECHA Chemical Information Database
NCI Online SMILES Translator and Structure File Generator
NIST Chemistry Web Book
OECD eChemPortal
PubChem
Wolfram Alpha
Cancer Data
California Proposition 65 (CA Prop 65)
Carcinogenic Potency Database (CPDB)
International Agency for Research on Cancer Monographs (IARC)
National Toxicology Program 12th Report on Carcinogens (RoC)
Environmental & Occupational
Environmental Health Criteria Monographs (EHC)
International Chemical Safety Cards (ICSCs)
National Library of Medicine Haz-Map
NIEHS CEBS (Chemical Effects and Biological Systems)
NIOSH Pocket Guide to Chemical Hazards (NPG)
NIOSH Publications Database
NTP Health Assessment and Translation
OSHA Permissible Exposure Limits (PELs)
Registry of Toxic Effects of Chemical Substances (RTECS®) (subscription-based)
US EPA Databases
US EPA’s Integrated Risk Information System (IRIS)
US EPA’s ChemView
US EPA’s EcoTox
US EPA’s Toxicity Reference Database (ToxRefDB)
US EPA’s Toxicity Data Warehouse (ACToR)
US FDA Databases
US FDA’s List of Color Additives for Foods, Drugs, Cosmetics, and Medical Devices
US FDA’s List of Indirect Food Contact Additives
US FDA’s List of Direct Food Additives
US FDA’s Everything Added to Food in the United States (EAFUS)
US FDA’s Inactive Drug Ingredients
US FDA’s Active Drug Ingredients
US FDA’s Informatics and Computational Safety Analysis
Food & Cosmetics
WHO Joint FAO/WHO Expert Committee on Food Additives (JECFA) publications: Technical Report Series and Toxicological Monographs
Cosmetics Ingredient Review (CIR)
The Good Scents Company Information System
In Silico Prediction Tools
Analog Identification Methodology (AIM). Finds similar structures with tox data.
CAESER. Descriptor-based models that predict REACH tox endpoints.
IHCP Predictive Toxicology. Free computational tools.
OECD QSAR Toolbox. Uses structures to categorize chemicals and predict endpoints.
OncoLogic™. Predicts cancer potential of chemicals.
Tox Match. Estimates skin irritation and sensitization based on structural similarity.
Tox Predict. Estimates toxic hazard based on chemical structure.
Tox Tree. Estimates toxic hazard by applying a decision tree approach.
(All free from EPA and EU)
Lit Search
Google Scholar
National Library of Medicine’s PubMed
Pharmaceuticals & Biologics
Drug Information Portal
EBI (European Bioinformatics Institute) Database
Reproductive Toxins
California Proposition 65 (CA Prop 65)
Tox Profiles
REACH Registered Substances (free tox profiles on 11,000 chemicals)
BIBRA Toxicology Profiles ($200 each)
NSF International Profiles ($25 each)
Tox Reference Books
Merck Index
Patty’s Toxicology (often available online from corporate and university libraries)
Sax’s Dangerous Properties of Industrial Materials (often available online from corporate and university libraries)
Report of the Task Group on Reference Man (great source of chemical body burden data)
A Small Dose of Toxicology (free E-book, introduction to toxicology)
Medical Device Regulations
Worldwide medical device regulations
US FDA’s Recognized Consensus Standards
Toxicology Terms
Open Toxipedia
Other Useful Sites
The EXtension TOXicology NETwork
European Centre for Ecotoxicology and Toxicology (reports on chemicals)
US Federal Register
Federal Register (publishes notices regarding acceptable limits of chemicals)
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