FutureTox V

New Technologies to Evaluate Organ-Specific Effects of Drugs and Chemicals

University of North Carolina at Chapel Hill Friday Center
Chapel Hill, North Carolina

About FutureTox V

FutureTox V: New Technologies to Evaluate Organ-Specific Effects of Drugs and Chemicals will focus on issues of interest to regulatory and investigative toxicologists and discuss new technologies and strategies that are being used to improve, reduce, and/or replace animal testing (3Rs). The conference also will have presentations on computational analysis and artificial intelligence (AI). For example, new technologies will need to be developed to meet the computational challenges that genomics poses for the near future—given highly distributed data acquisition that involves heterogeneous formats—as well as emerging opportunities for data reduction and real-time analysis.

The FutureTox series focuses on building the road for 21st-century toxicology and risk assessment practices, utilizing in vitro data and in silico models for predictive toxicology, and taking the high-throughput risk assessment paradigm forward to address challenges in implementing the emerging big-data toolbox for risk assessment and regulatory decision-making.

Background and Vision for the Conference

  FutureTox V Will Address

  • Microphysiological Systems (MPS) and Engineered Microtissues:
    These represent 3D tissue function in a way that more realistically represents human organ function and can be used in efficacy and safety testing for pharma, disease models and therapies, and hazard identification for environmental chemical management programs. Important issues are in the capacity to recapitulate or invoke human disease processes utilizing integrated and translational multi-omics approaches, bioinformatics, AI-based computational models, and multi-chip circuits.

  • Novel Cross-Cutting Technologies:
    These involve single cell transcriptomics, novel imaging tools, and other emerging cutting-edge methods for breaking down cellular functions into subtype-specific effects that are topographically linked to tissue physiology and organ function. Elucidating “subtype cellular functions” promises to revolutionize the way to assess local changes in a tissue that cascade from toxicant-induced changes at single cell resolution to altered organ function.

  • Computational Integration and Synthesis:
    Mechanistic understanding of biological and toxicological processes is becoming increasingly dependent on big data. AI (e.g., machine and deep learning) and virtual-reality technologies are examples of data-related innovations that herald a new era for biomedical research, requiring quantitative systems for extracting knowledge and concepts.

  • Managing Expectations:
    Short-term and long-term activities for pragmatic use of technologies to answer questions on organ-specific toxicity (e.g., 2D versus 3D, screening versus targeted testing, in vitro to in vivo extrapolation, kinetics and dynamics, etc.) will be addressed in the discussion and breakout group sessions.

By presenting these cross-cutting topics (e.g., technology used in a tissue type and big data), it is expected that individuals working on the technology side will learn about potential new applications, scientists working on a type of toxicity will become educated about new approaches they might use in their field, and all will become acquainted with ways to store and utilize the resulting data.


Through April 18, 2022
SOT Member
SLC Member
Federal Scientist
SOT Student/Postdoc Member
Student/Postdoc Nonmember
After April 18, 2022
SOT Member
SLC Member
Federal Scientist
SOT Student/Postdoc Member
Student/Postdoc Nonmember
All registration fees will be processed in US dollars.

Mail-In Registration

Download Form

When using the mail-in registration form, payment must be submitted in one of the following ways:

  • Check (please list all registrants on the check stub)
  • Money Order
  • Credit Card (Visa, MasterCard, Discover, or American Express)
  • US Government Purchase Order (check must be drawn from the US Department of the Treasury)
  • Wire Transfer (include an additional $40 processing fee)

Submit your completed registration via:

  • Mail:
    Society of Toxicology
    11190 Sunrise Valley Drive, Suite 300
    Reston, VA 20191-4375
  • Fax: 703.438.3113
  • NOTE: To prevent double-billing, if you are registering by fax, DO NOT mail your original registration form. SOT needs only one copy for processing.

Registration Terms and Conditions

Registration Cancellation Refund Policy: All requests for cancellations and/or refunds must be received in writing to SOT Headquarters. These refunds will be processed, less a $30 fee, following the CCT meeting by April 18, 2022.

SOT reserves the right to review all registrations and to determine that individuals or organizations meet the Society’s criteria for participation.

For individuals who are not members of SOT, participation in FutureTox V is available only to bona fide individuals who are engaged in or promote the field of toxicology or biotechnology research and support the growth and development of the toxicology field. For organizations, participation in FutureTox V is available only to bona fide organizations with public policy positions and business practices that are generally consistent with the Society’s mission, goals, reputation, and its policies and principles as determined by SOT. SOT reserves the right to review applications for participation to confirm that the applicant meets these criteria and may, at the Society’s sole discretion, reject a registration by any individual or business or withdraw registration privileges at any time if any individual or organization is found to be inconsistent with the Society’s principles and interests. By registering for FutureTox V, you are agreeing to the terms and conditions the SOT Code of Conduct policy and are agreeing to abide by the Health and Safety guidance listed below.

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Health and Safety

SOT looks forward to seeing you in Chapel Hill, North Carolina for FutureTox V: New Technologies to Evaluate Organ-Specific Effects of Drugs and Chemicals and is prioritizing the safety of all meeting participants in planning for and conducting the event.

The Society is monitoring safety, health, and travel guidance from the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and state and local health authorities. SOT will continually adjust its processes for the event in accordance with these directives.

Reviewed May 2022
There are no restrictions or measures imposed by executive order for the public. There are no travel restrictions in place for North Carolina, and visitors do not have to quarantine upon arrival. All guests attending a meeting on the UNC Chapel Hill campus must abide by UNC’s Community Standards, including, if applicable at the time of the meeting, complying with any mask requirements.




Abstracts should relate to the topics and themes for this CCT meeting and submission is open to all FutureTox V attendees. Registration status will be confirmed before publication, and only conference attendees' work will appear at the meeting and in program materials. There is no fee associated with submission. For additional details on topics and themes, please visit the “Background” section of this website. Further instructions for poster preparation will be shared upon acceptance. Accepted abstracts will be displayed during the poster session on Tuesday, May 10, 2022.

Graduate students and postdoctoral scholars are encouraged to submit abstracts. Based on availability of funding, travel support will be provided to graduate students and postdoctoral scholars based on the merit of their submitted abstract and confirmation of their presenting a poster at the FutureTox V conference. Awards will be presented only to those individuals who attend the conference and present a poster.

Users will be directed to Oxford Abstracts, where you must create an account to submit your abstract.

All submissions must be received by 11:00 PM ET on Friday, April 8, 2022.

Abstract Submission is Now Closed.

Hotel Information

There is a wide variety of hotel accommodations in the area. The listing below includes recommendations from the Chapel Hill Convention and Visitor Bureau, sorted by distance from the Friday Center.

  Courtyard by Marriott (0.3 miles)
  100 Marriott Way
  Chapel Hill, NC 27516

  Aloft Chapel Hill (1.2 miles)
  1001 South Hamilton Road
  Chapel Hill, NC 27517

  Hampton Inn & Suites Chapel Hill/Durham (2.3 miles)
  6121 Farrington Road
  Chapel Hill, NC 27517

  Holiday Inn Express (2.3 miles)
  6119 Farrington Road
  Chapel Hill, NC 27514

  The Carolina Inn (3.1 miles)
  6119 Farrington Road
  Chapel Hill, NC 27514

  Graduate Chapel Hill (3.5 miles)
  311 W. Franklin Street
  Chapel Hill, NC 27514

  Residence Inn (4.2 miles)
  101 Erwin Road
  Chapel Hill, NC 27514

  Sheraton Chapel Hill (4.4 miles)
  One Europa Drive
  Chapel Hill, NC 27514

  Hyatt Place Chapel Hill/Southern Village (4.7 miles)
  3690 S. Columbia Street
  Chapel Hill, NC 27514

Organizing Committee

Chair: Ivan Rusyn, MD, PhD

Texas A&M University, College Station, TX

Co-Chair: Thomas B. Knudsen, PhD

US EPA/NCCT, Research Triangle Park, NC

Patrick Allard, PhD

University of California Los Angeles, CA

Jamie J. Bernard, PhD

Michigan State University, East Lansing, MI

Suzanne C. Fitzpatrick, PhD, DABT

SOT Council Contact
US FDA/CFSAN, College Park, MD

Jill A. Franzosa, PhD

US EPA, Research Triangle Park, NC

Kevin S. McDorman, DVM, PhD, DACVP

Charles River, Frederick, MD

Donna L. Mendrick, PhD

US FDA/NCTR, Silver Spring, MD

Xi Yang, PhD

Collaborative Conferences Committee Liaison
US FDA, Silver Spring, MD


Diamond Level

Society of Toxicology (SOT) Logo

Scientific Liasion Coalition (SLC) Logo

Platinum Level




InSphero logo


Gold Level


Foundation for Chemistry

Nortis Bio

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 11190 Sunrise Valley Drive, Suite 300, Reston, VA 20191-4375