|President||Jon A. Hotchkiss|
|Vice President||Debra L. Laskin|
|Vice President-Elect||Matthew J. Campen|
|Secretary/Treasurer||Melanie L. Doyle-Eisele|
|Past President||Flemming R. Cassee|
|Councilors||Andrea De Vizcaya-Ruiz|
|Judith T. Zelikoff|
|Postdoctoral Representative||Donald Scott Anderson|
|Student Representative||Tamara L. Young|
Committee Member Bios
Dr. Jon A. Hotchkiss
Dr. Jon A. Hotchkiss has over 30 years of experience in respiratory cell biology and inhalation toxicology. His graduate research to develop immunoreagents to label, isolate, and quantitate pulmonary epithelial and capillary endothelial cells was conducted at the Oak Ridge National Laboratory. He developed expertise in in aerosol science and inhalation toxicology at the (Lovelace) Inhalation Toxicology Research Institute in Albuquerque, New Mexico. He has conducted numerous inhalation studies to environmental pollutants, tobacco smoke, and industrial chemicals, to study mechanisms of epithelial injury, adaptation, and repair including enzyme and mucin gene expression. As an Assistant professor at Michigan State University (MSU) he examined the role epithelial/inflammatory cell interactions in upper and lower airway remodeling using rodent models of chronic human respiratory diseases. Dr. Hotchkiss is currently the Sr. Inhalation Toxicologist and technical leader of the Respiratory Toxicology Laboratory in The Dow Chemical Companys Toxicology & Environmental Research and Consulting Laboratory in Midland, Michigan. His laboratory conducts acute, subchronic, and chronic guideline and mode of action studies in support of product registration, product stewardship, and human risk assessment activities for Dow businesses and external consortia. He is a consultant and subject matter expert for several Dow businesses; a member of Dows Human Subject Review Board, develops Dow industrial hygiene guidelines and has active research programs in respiratory sensitization and in vivo/in vitro dosimetry and target cell toxicity.
Dr. Debra L. Laskin
Dr. Laskin is a Distinguished Professor and Chair of the Department of Pharmacology and Toxicology, and the Roy A. Bowers Endowed Chair at Rutgers University Ernest Mario School of Pharmacy. She joined the faculty of Rutgers in 1982 after completing her Ph.D in Pharmacology and Toxicology at the Medical College of Virginia, followed by postdoctoral training at the Wistar Institute, University of Pennsylvania. She currently serves as Deputy of the Rutgers University NIEHS P30 Center of Excellence.
Dr. Laskin is well recognized for her contributions to toxicology in the area of nonspecific immunity and inflammation, with a specific focus on the role of activated macrophages and inflammatory mediators in the pathophysiology of xenobiotic-induced lung and liver injury. She has been continuously funded by NIH for her research for over 30 years and has published >200 papers, reviews and book chapters. She has also been recognized for her scientific contributions to toxicology by a number of different awards including the SOT Achievement Award, the SOT Frank R Blood (now the Board of Publications) Award, the Burroughs Welcome Toxicology Scholar Award, the SOT Women in Toxicology Mentoring Award, and most recently, the IRSS Career Investigator Award. Dr. Laskin has also been active in SOT, previously serving as a member of Council, the Awards Committee, the Continuing Education Committee, Secretary/Treasurer of Mechanisms SS, and Council member of Dermatology Specialty Section. She also served as Chair of the Toxicology Division of ASPET. Currently, Dr. Laskin is an Associate Editor for Toxicology and Applied Pharmacology and a permanent member of new SIEE NIH study section. She is also very active in mentoring and training graduate students and postdoctoral associates.
Dr. Matthew J. Campen
Dr. Matthew J. Campen is a Professor: Pharmaceutical Sciences at the University of New Mexico Health Sciences Center College of Pharmacy. Dr. Campen received a BS in biochemistry from Virginia Tech in 1994 and a Master of Science in Public Health concentrating on environmental health from the University of North Carolina at Chapel Hill, in 1997. He received his PhD, in environmental health from UNC Chapel Hill in 2000 followed by a postdoctoral fellowship at the Johns Hopkins University School of Medicine. Prior to his current appointment, he worked as an independent scientist at the Lovelace Respiratory Research Institute in Albuquerque. Dr. Campen is an expert in the cardiopulmonary health effects of air pollution, such as ozone, combustion emissions and nanomaterials. He is also broadly interested in the crosstalk of the cardiovascular and respiratory systems in health and disease, conducting basic and clinical research into the nature of comorbidities that promote cardiovascular illness. His primary research focus involves the impact of inhaled toxicants, especially common air pollutants, on vascular function and injury.
Dr. Melanie L. Doyle-Eisele
Dr. Doyle-Eisele is the Director of Life Sciences at Lovelace Respiratory Research Institute/Lovelace Biomedical and Environmental Research Institute/Lovelace Biomedical. She received BS form University of South Carolina and her MS and PhD from the University of North Carolina at Chapel Hill. Her main research emphasis areas intersect Drug Development from early model evaluation to completion of Investigational New Drug/New Drug Applications and Emergency Use Authorizations. This is conducted through her expertise in pharmacokinetics, pharmacology, toxicology and specialized capabilities in pulmonary disease, infectious disease, inflammation and injury. Her division has developed animal models of inflammation (pulmonary/other), acute distress and nervous system (primarily chemical and toxin injury), disposition (ADME and radionuclide models), toxicology (IND/NDA enabling and exploratory), radiation-induced injury (hematopoietic, gastrointestinal, and dermal), chemical injury, and infectious disease (select agent and non-select agent). Dr. Doyle-Eisele oversees Study Directors and technical staff with expertise in each of these research areas.
Dr. Flemming R. Cassee
Dr. Flemming R. Cassee is an inhalation toxicologist at the National Institute for Public Health and the Environment (RIVM) of the Netherlands since 1995 and is involved in the research on the adverse health effects of ambient particulate matter, nanomaterials and gaseous components. He supports government authorities at all levels, from the local to the international by coordinating and conducting research and providing. His international working experience involves collaborations with EU framework programs and projects and with other institutions. He serves in a number of international advisory committees including WHO and act as grant application reviewer for US EPA and other funding agencies. He has written and co-authored over a hundred scientific reports, book chapters and articles in international journals. He is the editor-in-chief of Particle and Fibre Toxicology, editorial board member of Inhalation Toxicology, Nanotoxicology and Air Quality, Atmospheres and Health. He also is a co-editor of the book “Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles.” He is currently the leading investigator of the Inhalation Toxicology unit of the Center for Sustainability, Environmental & Health, RIVM and is the president-elect of the Dutch Society of Toxicology.
Dr. Andrea De Vizcaya-Ruiz
Dr. Andrea De Vizcaya-Ruiz is a researcher in toxicology at the Department of Toxicology at the Center for Advanced Research and Studies (CINVESTAV-IPN) in Mexico. She studied Veterinary Medicine at the National Autonomous University of Mexico (UNAM) where she graduated in 1995, to continue a PhD in Toxicology at the University of Surrey in the United Kingdom in 2000. After completing a 2 year pos-doc at the Department of Toxicology at CINVESTAV-IPN she became a member of the Department as an assistant professor in 2002 and in 2013 she became associate professor and level II in the National Research System of the Mexican Council of Science and Technology (SNI-Conacyt). Dr. Andrea De Vizcaya-Ruiz has authored and co-authored more than 44 publications in indexed journals and chapter books, and has presented her work at international conferences. Dr. Andrea De Vizcaya-Ruiz has participated as an advisor in the Mexican Ministry of Health and the Mexican Ministry of Environment in the establishment of guidelines pertaining air pollution indexes and guidelines. She participates in the Editorial Board of Particle and Fibre Toxicology journal and a reviewer of a number of international scientific journals. She mainly develops studies on in vitro and in vivo models related with inhalation toxicology, related with the adverse health effects from the exposure to airborne particulate matter in ambient air, and has recently extended her research interests in the study of the biointeraction and safety of nanomaterials. Dr. Andrea De Vizcaya-Ruiz is a lecturer in the Preclinical Toxicology course and in the Mechanisms of Toxicology course, in the postgraduate program in Toxicology at CINVESTAV-IPN (http://toxicologia.cinvestav.mx/programas). Amongst her academic duties is also the mentoring of PhD (7) and MSc (16) thesis, as well as being the Principal Investigator for numerous projects funded by national and international agencies: Conacyt, EU, Fogarty Program-USA, amongst others. She is a member of the Mexican Toxicology Society and currently Vice-president for ICT2016 to be held in Mérida, Yucatán, Mexico.
Dr. Irfan Rahman
Dr. Irfan Rahman is a Professor of Environmental Medicine, Medicine (Pulmonary), and Public Health Sciences at the Environmental Health Sciences Center, University of Rochester, Rochester, New York. After postdoctoral work at the University of Miami, Georgetown University, and leading to faculty appointment at the University of Edinburgh, Scotland, he joined the University of Rochester as an Assistant Professor in 2004. He is a full member of the SOT and participated in various study sections (various panels of NHLBI, NIEHS, NCI, NCCAM, and VA). He has chaired and participated in numerous symposia and has published over 200 peer-reviewed research original articles (H-index 74), reviews, and book chapters in the field of pulmonary/inhalation redox biology relating to oxidative stress, biomarkers, inflammation, epigenetics, and cellular senescence. His research focuses on understanding the redox signaling, chromatin remodeling-epigenetic changes, involvement of sirtuins and HDACs in DNA damage/repair in cellular senescence, and mitochondrial dysfunction by environmental inhaled toxicants, as well as molecular targets for interventions. He is an Associate Editor of Nature Scientific Report, Journal of Inflammation, International Journal of COPD, and Experimental Lung Research, and editorial member of several basic science and respiratory journals. He has recently edited a book on Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions by Elsevier, and recognized as Highly Cited Researchers, 2014–2015 by Thomson Reuters in Pharmacology & Toxicology.
Dr. Judith T. Zelikoff
Dr. Judith T. Zelikoff is Professor in the Department of Environmental Medicine, New York University Langone Medical Center. She received her PhD from Rutgers School of Biomedical and Health Sciences. The major focus of Dr. Zelikoff’s research laboratory has long been the effects of inhaled toxicants on immune system function and the reproductive process. Ongoing studies include those using inhaled nanoparticles, particulate matter (PM), cigarette smoke or its components, as well as alternative tobacco products such as gutkha and hookah. One of her main interests is studying the effects of inhaled metal nanoparticles (oxides of cadmium or silver and gold) on embryonic, fetal, and postnatal development and growth. For instance, her work has shown exposure to inhaled cadmium oxide nanoparticles during pregnancy lead to shortened body length of newborns and leads to diminished rate of weight gain early in life and mechanisms for these actions are part of on-going studies in. Another focus of Dr. Zelikoff’s laboratory is how particulate matter in air pollution causes premature birth and low birth weight. She is trying to understand how exposure at different times during pregnancy can lead to premature birth/low birth weight as well as to determine the mechanisms involved and potential intervention strategies to improve the health of the baby. She has shown experimentally that exposure to PM can cause changes in the uterine environment that lead to premature birth and that timing and duration of exposure are both important factors. A long-time focus of Dr. Zelikoff’s laboratory is gaining a better understand for how cigarette smoking during pregnancy affects the unborn offspring, and how these effects increase a child’s susceptibility to diseases such as cancer or heart disease later in life (i.e., developmental basis of adult disease). Her laboratory has extended this work to examining how smokeless or “heat-not-burn” tobacco products can affect the reproductive process. These products, gutkha (South Asian product) and shisha smoked in a hookah (Middle Eastern product), are traditionally used by ethnic/immigrant populations, but are now being used with greater frequency by the population at large. These products, along with e-cigarettes are being studied for their toxic effects on male and female reproduction, immunity, and brain neurotransmitters which lead to addiction. Dr. Zelikoff has over 150 publications.
Dr. Ilona Jaspers
Dr. Ilona Jaspers, PhD, is a Professor in the UNC Department of Pediatrics, the Director of the Curriculum in Toxicology and the Deputy Director of the UNC Center for Environmental Medicine, Asthma and Lung Biology. Dr. Jaspers is a professor with more than 15 years of experience at the University of North Carolina at Chapel Hill who specializes in the effects of ambient air pollutants on respiratory immune dysfunction. She has established several human in vitro and clinical in vivo models to determine the adverse health effects induced by pollutant exposures. As the deputy director of the Center for Environmental Medicine, Asthma and Lung Biology, Dr. Jaspers collaborates extensively with investigators from UNC and the US Environmental Protection agency to conduct translational studies related to air pollution health effects. Research in Dr. Jaspers’ laboratory also focuses on the mechanisms by which exposure to air pollutants can enhance the susceptibility to and the severity of respiratory virus infections. Specifically, she is examining the effects of air pollutants such as woodsmoke, e-cigarettes, and cigarette smoke on influenza virus infections, using several in vitro models of the respiratory epithelium. Dr. Jaspers is also the director of the Curriculum in Toxicology, overseeing the training and mentoring graduate students as well as postdoctoral fellows.
Dr. Donald S. Anderson
Dr. Donald S. Anderson is a Postdoctoral Fellow at the University of Montana, where he is investigating changes in phagosome/lysosome lipid structure that results in membrane permeability after exposure to engineered nanomaterials. This includes using time-resolved fluorescence spectroscopy/microscopy to determine changes in lipid membrane local environments. Additionally, Dr. Anderson is working on a ViCTER grant supplement project investigating the development of autoimmunity from exposure to nanomaterials. He received his doctorate in Pharmacology and Toxicology from the University of California, Davis in 2014 and was awarded a Kirschstein-NSRA F32 postdoctoral fellowship in 2016.
Tamara Young is third-year PhD student in the department of Pharmaceutical Sciences at the University of New Mexico. Tamara graduated with a Bachelor of Science in Biology from Benedict College, Columbia, SC. Prior to enrolling at the University of New Mexico, she worked as a research technician at the Center for Developmental Pharmacology and Toxicology, Nationwide Children’s Hospital, Columbus, OH and in the department of Pathology, University of Manitoba, Canada. Her research focuses on the role of inhaled toxicants, particularly air pollutants and nanomaterials, and the cardiopulmonary-systemic crosstalk in the pathogenesis of disease.