|President||Melanie L. Doyle-Eisele|
|Vice President||Kymberly M. Gowdy|
|Vice President-Elect||Laura Van Winkle|
|Past President||Judith T. Zelikoff|
|Natalie M. Johnson|
|Robert M. Tighe|
|Katie E. Zychowski|
|Postdoctoral Representative||Emma Karey|
|Student Representative||Michael Yaeger|
To email the Inhalation and Respiratory Specialty Section Leadership, please send an email to SOTHQ@toxicology.org.
Committee Member Bios
Melanie L. Doyle-Eisele, President
Dr. Doyle-Eisele is the Senior Director of Laboratory Animal Sciences and a Senior Scientist at Lovelace Biomedical (Lovelace Biomedical Research Institute, Lovelace Respiratory Research Institute) where she oversees the execution of core life sciences research, responsible for technical guidance, resource, and budget allocation, operational flow and compliance, integration with appropriate subject matter experts, and interfaces with Sponsors/Clients for model development, evaluation, and drug testing. In addition to testing facility management responsibilities and serving on Lovelace committees (Radiation Safety Chair and IACUC committee), she conducts research, performs studies, and leads programs in drug development, and medical countermeasures (CBRNE), biomarkers, ADME, pharmaceutical and environmental exposures. She received her Doctorate from UNC-Chapel Hill from the School of Public Health in 2006, Masters from UNC in 2003, and began a postdoctoral position before heading to New Mexico in 2007 to further her scientific journey. Dr. Doyle-Eisele has been a member of SOT since 2007. She has served as officer the Mixtures Specialty Section, Inhalation and Respiratory Specialty Section, and Mountain West Regional Chapter. In addition to SOT activities, she is actively involved in review panels for several focus areas and has authored or co-authored more than 60 peer reviewed publications, completed more than 500 regulated studies, and has led studies as part of approval for several approved Investigational New Drug (IND) or Emergency Use Authorization (EUA, National Stockpile) applications to the regulatory agencies.
Kymberly M. Gowdy, Vice President
Dr. Gowdy is an Associate Professor in the Department of Internal Medicine at Ohio State University, where she examines mechanisms of how air pollution increases susceptibility and severity of infectious and inflammatory lung diseases. Specifically, her research examines how danger-associated molecular patterns generated in the lung after air pollution exposure shape the innate immune response. She received her doctorate in Immunology and Toxicology from the North Carolina State University in 2008 and was a postdoctoral fellow at Duke University from 2008–2011 and the National Institutes of Environmental Health Sciences from 2011–2014. Dr. Gowdy is the author/co-author of 50 publications including peer-reviewed articles, reviews, and book chapters. She has been an active member of SOT and the Inhalation Respiratory Specialty Section since 2007. She has previously served SOT as the Councilor for the Inhalation and Respiratory Specialty Section, Councilor for the Cardiovascular Specialty Section, and President for the North Carolina Society of Toxicology.
Laura Van Winkle, Vice President-Elect
Dr. Laura S Van Winkle is a Professor of Respiratory Toxicology in the School of Veterinary Medicine Department of Anatomy, Physiology and Cell Biology at UC Davis. She received a BS with honors from UC Santa Barbara in Pharmacology and worked in the biotech sector for several years before earning her Ph.D. in Pharmacology and Toxicology from UC Davis. Following completion of her American Lung Association Research Training Fellowship, she joined the faculty at UC Davis in 1997. Her laboratory is at the Center for Health and the Environment where she is the Director of the Cellular and Molecular Imaging Core and Associate Director of the Center. She is a Diplomate of the American Board of Toxicology (DABT) and is a current member of the American Thoracic Society (ATS) Environmental Occupational and Public Health planning committee. She has published over 95 research articles in the fields of inhalation toxicology, developmental lung biology, chemical bioactivation, and lung injury and repair. Her research has focused on the interaction of environmental pollutants and specific lung regions, such as the distal conducting airway epithelium of the lung, and how that contributes to lung remodeling across the lifespan. Currently, she is the Chair of the UC Davis Graduate Group in Pharmacology and Toxicology and Director of the UC Davis NIEHS T32 for Advanced Training in Environmental Health Sciences. Her research lab has mentored over 115 diverse undergraduate and graduate students in STEM. She has served on many NIH Study Sections, including SIEE as a standing member, and as an Associate Editor for the SOT society journal Toxicological Sciences. She was the recipient of the SOT Inhalation and Respiratory Specialty Section Young Investigator Award and the Women in Toxicology Mentoring Award and has previously served IRSS as a councilor and as secretary/treasurer. She has been a full member of SOT since 1998.
Meghan Rebuli, Secretary/Treasurer
Dr. Meghan Rebuli is an inhalation toxicologist and Assistant Professor in the Department of Pediatrics at the University of North Carolina at Chapel Hill. Her research focuses on sex differences in response to environmental toxicants, such as tobacco products, wood smoke, and ozone, in the respiratory innate immune system. Dr. Rebuli earned her doctorate from North Carolina State University in 2015 where she studied neuroendocrine toxicology and was a postdoctoral fellow at the University of North Carolina at Chapel Hill from 2015–2020 studying inhalation toxicology. Dr. Rebuli’s research has resulted in authorship/co-authorship of 17 peer-reviewed publications in journals such as Toxicological Sciences, the American Journal of Physiology Lung Cellular and Molecular Physiology, and the American Journal of Respiratory and Critical Care Medicine, and two book chapters. Dr. Rebuli has been a member of SOT since 2015 and has regularly participated in the national meeting. She served as the postdoctoral representative for the Women in Toxicology special interest group from 2019–2020, was on the Awards Committee and Newsletter Committee from 2016–2020, in addition she served as WIT Newsletter Assistant Editor from 2018–2020. Dr. Rebuli has also chaired Inhalation and Respiratory Specialty Section (IRSS) mini-symposia and poster sessions and was a CE course volunteer. In 2019, she proposed a symposium in concert with the IRSS, which was programed and held during the 2020 virtual meeting. Dr. Rebuli has immensely benefited from involvement with IRSS, winning the Postdoctoral Award, Donald E. Gardner Education Award, and the Paper of the Year Award, and she looks forward dedicating service back to the Specialty Section which has provided so many wonderful opportunities to her, other trainees, and young investigators.
Judith T. Zelikoff, Past President
Dr. Judith T. Zelikoff is Professor in the Department of Environmental Medicine, New York University Langone Medical Center. She received her PhD from Rutgers School of Biomedical and Health Sciences. The major focus of Dr. Zelikoff’s research laboratory has long been the effects of inhaled toxicants on immune system function and the reproductive process. Ongoing studies include those using inhaled nanoparticles, particulate matter (PM), cigarette smoke or its components, as well as alternative tobacco products such as gutkha and hookah. One of her main interests is studying the effects of inhaled metal nanoparticles (oxides of cadmium or silver and gold) on embryonic, fetal, and postnatal development and growth. For instance, her work has shown exposure to inhaled cadmium oxide nanoparticles during pregnancy lead to shortened body length of newborns and leads to diminished rate of weight gain early in life and mechanisms for these actions are part of on-going studies in. Another focus of Dr. Zelikoff’s laboratory is how particulate matter in air pollution causes premature birth and low birth weight. She is trying to understand how exposure at different times during pregnancy can lead to premature birth/low birth weight as well as to determine the mechanisms involved and potential intervention strategies to improve the health of the baby. She has shown experimentally that exposure to PM can cause changes in the uterine environment that lead to premature birth and that timing and duration of exposure are both important factors. A long-time focus of Dr. Zelikoff’s laboratory is gaining a better understand for how cigarette smoking during pregnancy affects the unborn offspring, and how these effects increase a child’s susceptibility to diseases such as cancer or heart disease later in life (i.e., developmental basis of adult disease). Her laboratory has extended this work to examining how smokeless or “heat-not-burn” tobacco products can affect the reproductive process. These products, gutkha (South Asian product) and shisha smoked in a hookah (Middle Eastern product), are traditionally used by ethnic/immigrant populations, but are now being used with greater frequency by the population at large. These products, along with e-cigarettes are being studied for their toxic effects on male and female reproduction, immunity, and brain neurotransmitters which lead to addiction. Dr. Zelikoff has over 150 publications.
Natalie M. Johnson, Councilor
Dr. Johnson is currently an Associate Professor in the Department of Environmental & Occupational Health at Texas A&M University. Her research group is currently investigating the effects of air pollution on infant immune and respiratory dysfunction, including oxidative stress and stress-activated signaling pathways as targets for protection. In vivo findings reveal a window of pulmonary immunosuppression in offspring following prenatal PM exposure, and this model served as the basis for characterizing mechanisms underlying PM-driven immune modulation and neonatal respiratory infection risk. Dr. Johnson obtained her Ph.D. in Toxicology, with an emphasis on exposure biomarkers and translational toxicology, from Texas A&M University in 2010. She then completed a post-doctoral fellowship at Johns Hopkins University, focusing on molecular toxicology and mechanisms of chemoprevention. Dr. Johnson has been an active member of SOT since 2006 and served in multiple leadership positions, including peer or host mentor in the Undergraduate Education Program, councilor for the OPHSS (2015&dash2017), councilor/secretary for LSSOT (2019–2020), where she is currently serving as vice-president (beginning in 2021).
Katie E. Zychowski, Councilor
Dr. Zychowski is an Assistant Professor in the University of New Mexico-Health Sciences Center where she studies biological mechanisms of inhaled exposures such as metal-based particulate matter and woodsmoke. She received her doctorate in Toxicology from Texas A&M University in 2014 and was a Postdoctoral Fellow at the University of New Mexico from 2014-2018. Dr. Zychowski has served as an ad hoc member of several study sections for both NIH/NIEHS and CDC/NIOSH. In addition, she has also peer-reviewed toxicological profiles for the Agency for Toxic Substances and Disease Registry (ATSDR). She has authored 29 peer-reviewed publications and 2 book chapters. She has been a member of the SOT since 2010 and has served the SOT as a member of the Committee for Diversity Initiatives (2010–2014), the Cardiovascular Toxicology Specialty Section (CVTSS) Postdoctoral Representative (2016–2018), the CVTSS Treasurer (2020–2022), and was the inaugural recipient of the IRSS Don E. Gardner Education Award
Patricia Silveyra, Councilor
Dr. Silveyra is an Associate Professor in the Department of Environmental and Occupational Health at the Indiana University Bloomington School of Public Health, where she conducts research on sex differences in lung disease and sex-specific mechanisms of lung inflammation triggered by environmental exposures. Dr. Silveyra is an Argentine-American scientist who received her doctorate from the University of Buenos Aires in 2007 and was a postdoctoral fellow at Penn State College of Medicine from 2008–2011. Dr. Silveyra has served on the LIRR, SIEE, and IRAP NIH study sections, and on multiple international review panels for federal and foundation programs. She is on the Editorial Board of the American Journal of Physiology-Lung Cellular and Molecular Physiology, and Frontiers in Pharmacology-Respiratory Pharmacology. She is author/co-author of over 50 peer-reviewed publications, 2 books and 7 book chapters. She has been a member of the SOT since 2017 and has participated in multiple mentoring events, served as poster session leader and speaker at SOT meetings, and has mentored trainees and junior faculty that are SOT and HOT members. She has also recently established an alliance between SOT and SACNAS members to increase participation of URM trainees in activities organized by the society.
Robert M. Tighe, Councilor
Dr. Tighe is an Associate Professor of Medicine at Duke University, where he works on defining susceptibility factors for pulmonary responses to air pollution with a particular interest in understanding crosstalk between macrophages and epithelial cells. He received his doctorate in Medicine from the University of Tennessee College of Medicine in 2002, did his residency and chief residency in Internal Medicine at Boston University and his clinical and research fellowship in Pulmonary and Critical Care Medicine at Duke University from 2006–2010. Dr. Tighe has served on the Editorial Board of the American Journal of Respiratory Cell and Molecular Biology, is the Vice-Chair of the Publications and Policy Committee for the American Thoracic Society, and has been a regular member of the Pulmonary Section Review Committee for the Department of Veterans Affairs. He has authored/co-authored 37 publications including peer-reviewed articles and/or book chapters. He has been a member of the SOT since 2016 and has been a member of IRSS and the North Carolina Chapter of SOT since joining.
Emma Karey, Postdoctoral Representative
Emma Karey obtained her doctorate in Pharmacology and Toxicology from the University of California at Davis in 2018, where she characterized the autonomic mechanisms underlying cardiovascular dysfunction induced by environmental tobacco smoke. Upon graduating, she joined the Department of Environmental Medicine at NYU Langone as a postdoctoral researcher working with Drs. Terry Gordon and Michael Weitzman to evaluate the health effects of alternative tobacco products (ATPs), including electronic cigarettes and hookah water pipes. Over the past three years, Dr. Karey has identified novel respiratory effects — ones associated with ATPs that have not been observed with more traditional combustible-tobacco products. She also spearheaded a study that found unique behaviors among ATP users that might explain these differences in respiratory toxicity. This past year, Dr. Karey coauthored several additional publications, including a comprehensive review of e-cigarette toxicity and multiple epidemiological papers identifying novel associations between vaping, inflammation, and mental health. Most recently, she has found respiratory inflammation in children passively exposed to vaping emissions in the home, providing some of the first data to suggest that secondhand e-cigarette exposures may cause harm.
Michael Yaeger, Graduate Student Representative
Mr. Yaeger is a PhD student at Ohio State University in Dr. Kymberly Gowdy's laboratory. His Ph.D. research is focused on how dietary lipids can alter the pulmonary and systemic inflammatory responses to the criteria air pollutant, ozone. Prior to enrolling in the Ph.D. program at Ohio State, Mr. Yaeger received his BS (2016) in engineering and MS (2018) in biomedical engineering at East Carolina University. From 2018–2020, Mr. Yaeger worked at Lovelace Biomedical as a research associate, where he assisted study directors with study management and reporting, as well as contributed to publications on model development for irradiation in minipigs and non-human primates. Michael has 1 first author publication (under review), co-authorship on 5 publications (2 under review), and has presented his research by oral presentation or poster 12 times (including 2020 Ohio Valley SOT), earning 3 first-place awards (including at 2020 Ohio Valley SOT for graphical abstract) and 1 third-place award (2020 Ohio Valley SOT Tox on the Clock). Although Michael is in his first year as a SOT member, he is excited to get involved and become a contributing member to IRSS and SOT.