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Upcoming Events

NorCal SOT 2020 Webinar Series

November 12, 2020, 12:00 Noon–1:30 PM (PT)

QSAR Approaches in Toxicology for PMIs

Speaker: Alejandra Trejo-Martin, BSc, MBA, Gilead

Overview of Acute Toxicity, Its Use in Classification and Labelling (C&L), the 3Rs and the Objective of Project

Speaker: Jean Lord, PhD, Genentech

Overview of In Silico Models for Acute Toxicity Prediction and Study Design

Speaker: Glenn Myatt, PhD, Leadscope (an Instem company)

Results, the Important of Expert Review, How to Perform an Expert Review

Speaker: Catrin Hasselgren, PhD, Genentech

How to Incorporate In Silico Assessments into the C&L Workflow and Concluding Remarks

Speaker: Melissa Masuda-Herrera, PhD, Gilead

Registration link >>

Past Events

Webinar Series

October 15, 2020

Utility of Digital Pathology and Image Analysis in Nonclinical Drug Development and an Introduction into Machine Learning

Webinar Recording

Famke Aeffner, DVM, PhD, DACVP, Principal Pathologist; Amgen Inc, Amgen Research, Translational Safety and Bioanalytical Sciences, South San Francisco, CA, USA; and
Vanessa Schumacher, DVM, MS, DABT, DACVP, Head of Digital Pathology and Tissue Technologies; Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland

Webinar Series

September 10, 2020

Using Publicly Available Resources for Identifying and Characterizing Chemicals of Potential Toxicity Concern: Proof-of-Concept with Chemicals That Affect Cancer Pathways

Speaker: Shoba S. Iyer, PhD, Office of Environmental Health Hazard Assessment, Safer Alternatives Assessment and Biomonitoring Section

Biology Dictates Model Validity: A Case Study with Sulfuryl Fluoride

Speaker: Daisy Dong, PhD, California Environmental Protection Agency, Department of Pesticide Regulation, Risk Assessment Section

Northern California 2019 Fall Symposium

October 24, 2019

Venue: South San Francisco Conference Center, San Francisco, California

“The Hematopoietic System: Therapeutics, Toxic Responses, and Strategies for 21st Century”

Preliminary Agenda


Brian Cathers | John Leighton | Nancy Everds | Kathleen Meyer

Northern California 2019 Spring Symposium

April 25, 2019

Venue: South San Francisco Conference Center, San Francisco, California

NorCal SOT Annual Reception at the 58th SOT Annual Meeting

Tuesday, March 12, 2019

Venue: Tir Na Nog Irish Bar and Grill

NorCal SOT Career Panel

Monday, February 25, 2019 from 6:00–8:00 pm

Venue: Berkeley Way West Building, Rm 5101 (Address: 2121 Berkeley Way)

Northern California 2018 Fall Symposium

October 25, 2018

Venue: South San Francisco Conference Center, San Francisco, California

"A New Hope: Nonclinical Challenges in the Burgeoning Field of Gene Therapy"

Draft Agenda

Online Registration

Northern California 2018 Spring Symposium

April 27, 2018

Venue: South San Francisco Conference Center, San Francisco, California

“Immuno-Oncology: Opportunities, Therapeutic Approaches, and Safety Considerations”

Meeting Agenda

Online Registration


Keith Bahjat | Allyson Byrd | Sanjay Sethi | Greg Bannish | Henry Li | Herve Lebrec

NorCal SOT Annual Reception at the 57th SOT Annual Meeting

Our Reception this year was held on Tuesday, March 13, 2018
at Zinc Bistro & Bar, from 7:00 pm–10:00 pm.

Northern California 2017 Fall Symposium

September 28, 2017—South San Francisco Conference Center, San Francisco, California

“The 3R’s”

Meeting Agenda

Fall Symposium Presentations:

Clive Roper | Lisa Wong | Gertrude-Emilia Costin | Shaun D. McCullough | Glenn J. Myatt

Northern California 2017 Spring Symposium

Tuesday, May 16, 2017—South San Francisco Conference Center

“Combination Therapy: Fundamentals, Advances, and Case Studies” 

Our eight speakers provided seminars on topics related to development of combination therapeutics for small and large molecules (peptides, proteins, antibodies). General topics include toxicology/regulatory considerations, pharmacokinetic/pharmacodynamic, immunogenicity, bioanalytical chemistry, manufacturing, and production. This one-day event was held on May 16, 2017 from 7:30 am to 5:30 pm at the South San Francisco Conference Center located at 255 South Airport Boulevard, South San Francisco, CA 94080. 

Final Agenda

Spring Symposium Presentations:

Joe Francisco | Jessica Hawes | Phil Gatti

NorCal SOT Reception at the 56th SOT Annual Meeting

Our Reception this year was held on Tuesday, March 14, 2017
at Tir Na Nog Irish Bar and Grill, from 7:30 pm–10:30 pm.

Northern California 2016 Fall Symposium

Tuesday, October 18, 2016—South San Francisco Convention Center, South San Francisco, California

A diverse and interesting agenda has been prepared for this meeting. The scientific themes for this meeting will be “Infectious Diseases” and “Cardiovascular Safety Pharmacology.” In addition to the scientific program there will also be a Mentoring Luncheon open to interested Mentors and Mentees as well as a poster session. Please see the meeting agenda for further details.

Meeting Agenda

Managing the Risks of Leachables from Pharmaceutical Manufacturing Equipment—A Blueprint for Success

April 20, 2016—San Diego, California

Join NSF and PharmaEd for our seminar, “Managing the Risks of Leachables from Pharmaceutical Manufacturing Equipment—A Blueprint for Success” April 20, San Diego, California. Pharmaceutical companies understand that a leachables risk assessment of the components in their manufacturing trains must be performed; however, it is unclear as to what factors should be considered and what role the vendors of equipment should take in this assessment. This training course will describe a practical, materials-based approach to manage risk that has worked in meeting the US FDA’s expectations for equipment evaluations.

Northern California 2016 Spring Symposium

Tuesday, April 26, 2016—SRI International, Menlo Park, California

We have an exciting line up covering diverse topics including latest advances in ADCs, epigenetics, reprotox, and genetox (agenda below). In addition, we would like to introduce our graduate and postdoctoral achievement award winners who will share their research.

Final Agenda

NorCal 2015 Fall Symposium

Thursday, October 22, 2015—South San Francisco Conference Center

A Tail of Two Fields: Reproductive & Juvenile Toxicity, and Public Health & Risk Assessment The afternoon session will be a tribute to the late Dr. George Alexeeff and his legacy at Cal/EPA. Dr. Alexeeff was the Director of OEHHA at CalEP and a Past President of NorCal SOT.

Final Agenda

NorCal SOT Preclinical Drug Safety Networking Dinner—It’s a mAb, mAb, mAb World

September 2, 2015—Chalet Ticino, Foster City, California

The Bay area toxicology discussion group is looking forward to our next get-together on September 2, 2015. The discussion topic will focus on post translational modifications for monoclonal antibodies. Basically, what types of modification are observed during development, which have biological/DMPK ramifications, and what preclinical strategies are pragmatic in managing these CMC issues Kathila Rajapaksa from Genentech will give a short (10–15 minute) introduction and then help lead the discussion. This presentation will set the basics for a Q&A session to follow.

NorCal SOT Spring Symposium

April 23, 2015—South San Francisco Convention Center, South San Francisco, California

Agenda | Speaker Flyer

Preliminary Program:

“Preclinical Drug Development, Bio-Threats and Biomarkers of Toxicity”

  • Rebecca Abergel, PhD, Chair of Radioactive Drug Research Committee, Lawrence Berkeley National Laboratory: Development of New Therapeutics for Radionuclide Decorporations: From Discovery to IND
  • Tracy Goldstein, PhD, Associate Director and Professor, UC Davis, One Health Institute: Using a One Health Approach to Reduce Pandemic Risk and Promote Global Health: PREDICT, A Project of USAID’s Emerging Threats Program
  • Serguei Liachenko, MD, PhD, US FDA: Preclinical Development of Neurotoxicity Biomarkers Using MRI
  • Jon Mirsalis, PhD, DABT, Managing Director of Biosciences, SRI International: Biomarkers of Cardiac Toxicity
  • Gene Garrard Olinger Jr., PhD, MBA, Principal Advisor Science, MRI Global IncDevelopment of Passive Immunity for Ebola Virus Infections Through Convergence of Science & Technology: Mice, Primates and Plants
  • Frances Shafforecipient of the NorCal SOT Graduate Student Achievement Award: Effects of Organophosphorus Pesticides (OPs) on Airway Physiology
  • Fenna Sillé, recipient of the NorCal SOT Postdoctoral Fellow Achievement Award: Arsenic and Innate Immunity: Macrophage Function Upon Arsenic Exposure

Additional Activities:

  1. Lunch with an Expert–opportunity for students and postdocs to network with professionals
  2. Poster presentation (limited to students and postdocs)–opportunity for students and postdocs to present their research

K–12 Event

April 25, 2015

NorCal SOT will be holding another Science Day event in partnership with Berkeley Undergraduate Toxicology Association (ToxSa) and Peninsula Girl Scout on Saturday April 25, 2015. We are in need of volunteers to serve as expert toxicologists addressing parents and students questions during the day and supporting the ToxSa student when needed. We need total of 4–6 volunteers.

The event will be held at the following location: LGI Room, Audubon Elementary School, 841 Gull Avenue, Foster City, California 94404

This is a fun event that has become a tradition for NorCal and we look forward to your participation.

If you are interested to volunteer, please email Toufan Parman.

Special Joint SJSU MBT - SOT Seminar

April 2, 2015, 7:00 PM–9:00 PM

Venue: SJSU Boccardo Business Complex (BBC) 0032 Conference Rm

NorCal Reception at the SOT Meeting in San Diego

Tuesday, March 24, 2015, 7:30 PM–9:30 PM

Venue: Yard House, 1023 4th Avenue, San Diego, CA 92101

NorCal SOT Speed Mentoring

Thursday, January 15, 2015,  6:00 PM–9:00 PM

Venue:  Sudwerk Restaurant & Brewery, 2001 2nd Street, Davis, CA 95618

NorCal SOT Preclinical Drug Safety Networking Dinner

Thursday, December 4, 2014

Venue: Chalet Ticino, 1058-C Shell Boulevard, Foster City, CA 94404 (in Charter Square Center)

NorCal SOT Preclinical Drug Safety Networking Dinner

There’s no Formula to Formulation

Where: Chalet Ticino

Address: 1058-C Shell Boulevard, Foster City, CA 94404 (in Charter Square Center)

Date: Thursday, December 4

Time: 6:15 PM

The Bay area toxicology discussion group is looking forward to our next get-together on December 4, 2014. We will start the evening with network time with wine and appetizers. Please select one of the three menu choices below when you register for this 3-course dinner that includes: salad or soup, entry, and then choice of sorbet or ice cream:

  • Ribeye luganese over portobella mushrooms and creamy polenta
  • Veal piccata served with potato gnocchi
  • Fresh petrale sole sauteed in a white wine, lemon butter sauce served with fresh vegetable

The discussion topic will focus on formulation and is primarily directed toward toxicologists in the drug development field to understand the formulation process, and to understand how it would affect preclinical safety evaluations.  We will begin with a 10–15 minutes presentation from Novartis talking about the formulation support at each R&D step from lead optimization to phase I. Topics to be covered include: Once a lead molecule is identified for further development, what do the formulation folks do? How do they start? What are the important concepts? This presentation will set the basics, and then we will have a Q&A session.

Northern California Regional Chapter Fall Symposium

October 21, 2014, 8:30 AM–5:00 PM

Venue: Genentech Building 42, South San Francisco

Symposium Agenda, Speaker Bios, and Abstract Information

Northern California Regional Chapter Spring Symposium

April 29, 2014, 8:30 AM–5:00 PM

Venue: David Brower Center, 2150 Allston Way, Berkeley, CA

Topics: In vitro safety profiling of drugs and chemicals, neurotoxicology, neuroelectrophysiology, screening for drug abuse liability, current topics in therapeutic proteins, and more!

Symposium Agenda

UC Davis Careers in Toxicology Event

April 2, 2014, 4:00 PM–8:00 PM

The Careers in Toxicology Event will be held at UC Davis! The chapter will host the event featuring a panel discussion with professionals with government, academic, or industry careers. Panelists discuss their jobs, their path in gaining their position with students, answering questions and concerns about careers in toxicology. There will be a networking event following the panel discussion to allow for further discussion and mentorship. If you would like to attend as a panelist, mentor or student please contact Sandra Chang.

K–12 Event

April 6, 2014, 1:00 PM–6:00 PM

We are planning another K–12 education event in collaboration with Berkeley Toxicology Student Association (ToxSA) and Girl Scouts. This event will be catered to 6th–8th grade students. The event will be held at Audubon Middle school in Foster City, California. We are looking for toxicology volunteers to help with various activities. This is a fun event and last year not only the students but also the volunteers enjoyed it. If you are interested in volunteering for this event please contact Toufan Parman.

NorCal SOT Reception—2014 Annual Meeting, Phoenix, Arizonia.

Date: Tuesday, March 25
Location: Arrogant Butcher, 2 E Jefferson St, Ste 150, Phoenix AZ 85004
Time: 7:00 PM–9:00 PM

NorCal SOT Preclinical Drug Safety Networking Dinner

Wednesday, December 4, 2013

Sapore Italiano
1447 Burlingame Ave
Burlingame, CA 94010

NorCal 2013 Fall Symposium

Thursday, October 24, 2013

South San Francisco Convention Center
225 South Airport Blvd
South San Francisco, California

“ADME and Its Role in Toxicology”

  • Mitochondrial Toxicity of Nucleoside Analogs: Joy Feng, PhD, Sr. Scientist, Gilead Sciences
  • Role of Metabolism in Respiratory Toxicity: Alan Buckpitt PhD, Professor Molecular Biosciences, UC Davis
  • Role of Ceruloplasmin in Mn Distribution and Toxicity: Donald Smith PhD, Professor Physical and Biological Sciences, UC Santa Cruz
  • Chemoproteomic and Metabolomic Strategies for Drug Discovery and Toxicology:  Keynote Speaker, Daniel Nomura PhD, Assistant Professor Nutritional Sciences and Toxicology, UC Berkeley
  • Transporters in Metabolism and Toxicity: Joseph Ware PhD, Sr. Scientist, Genentech, Inc.
  • How Drugs Get into the Brain & Assessment of Brain Levels: Carol Green PhD DABT, Senior Director, Toxicology and Pharmacokinetics, SRI International

Speed Mentoring

Tuesday, October 1, 2013

2001 2nd Street
Davis, CA 95618

NorCal SOT Preclinical Drug Safety Networking Dinner—Open Forum

After three popular events in 2012, we are organizing another dinner for those involved in pharmaceutical research and development. The idea, as before, is to get to know others in our field and to learn from each other.

Tuesday, July 23, 2013

Sapore Italiano
1447 Burlingame Ave, Burlingame, CA 94010

NorCal 2013 Spring Symposium

Tuesday, April 23, 2013

South San Francisco Convention Center
225 South Airport Blvd, South San Francisco

The NorCal Society of Toxicology Presents: Speed Mentoring

Wednesday, January 30, 2013
6:00 PM–9:00 PM

Pyramid Alehouse
901 Gilman St.
Berkeley, California 94710

  • Network with fellow scientists from around the Bay Area
  • Learn about toxicology career opportunities and/or share what path you took to your career
  • Practice your ‘elevator speech’
  • Enjoy delicious drinks and appetizers

Speed Mentoring Flyer

NorCal SOT Networking Dinner

Title: Safety Considerations in Developing Drugs for Epigenetic Targets
Where: Genentech, Building 83, conference room 1A
Address: 611 Gateway Blvd., South San Francisco, California 94080
Date: Thursday, December 13
Time: 6:00 PM–8:00 PM


6:00 PM–6:20 PM: Arrival, networking, appetizers will be served

6:20 PM–6:50 PM: Presentation: Jatinder Singh, Sr. Scientist, Safety Assessment, Genentech, Inc.

6:50 PM–7:30 PM: Dinner with group discussion of hypothetical case study and questions

7:30 PM–8:00 PM: Open discussion, conclusion, departure

NorCal Fall 2012 Symposium

“New Frontiers in Oncology Drug Development”

Topics: Developing Antibody Drug Conjugates (ADCs), Epigenetics, cancer and micro RNAs, and more!

Date: September 27, 8:30 AM–5:00 PM

Meeting Presentations

NorCal SOT ‘25th Anniversary’ Spring Symposium

Path Forward with the Revised ICH-S2 Genetox Guidelines
Endocrine Modulators in the Environment and Medicine
New Perspectives in Antibody Drug Development
NorCal SOT ‘25th Anniversary’ Reception

When: April 19 , 8:45 AM–6:00 PM (lunch provided with registration)

Where: SRI International Conference Facility, Menlo Park

Registration deadline: April 16 (end of day)

NorCal Biopharma Preclinical Drug Safety Networking Dinner

Tuesday, April 3, 2012
6:00 PM–8:00 PM

Location: Elan Pharmaceuticals, South San Francisco, California

Speaker: Thomas Gelzleichter, Genentech
Topic Title: Biosimilars

NorCal SOT 2011 Fall Meeting

Thursday, October 6, 2011

SRI International Conference Facilities
Menlo Park, California

This one-day event will feature morning presentations on stem cells followed by an on-site networking lunch. The afternoon presentations will cover current topics in toxicology, and the day will conclude with a wine and reception.

NorCal SOT Spring Symposium

Wednesday, April 13, 2011

Berkeley City Club
2315 Durant Avenue
Berkeley, CA 94704-1606

Event Flyer


Charles River Laboratories
MPI Research
WIL Research Laboratories

NorCal SOT Reception—2011 Annual Meeting, Washington, D.C.

All Annual Meeting attendees from Northern California are cordially invited to attend the NorCal SOT reception.

Date: Monday, March 7
Location: District ChopHouse & Brewery
509 7th Street, NW, just 1/2 block from the Verizon
Center and Gallery Place/Chinatown Metro
Time: 6:30 PM–8:30 PM

Career Workshop at UC Davis

NorCal SOT hosted an outreach workshop at UC Davis January 20, 2011. The workshop, “Toxicology Related Career Options,” gave students the opportunity to learn from, and interact with, professionals in toxicology-related careers. With 79 students and 16 toxicology professionals in attendance the event was a great success!

2010 Fall Meeting

Northern California SOT will be hosting a Fall Symposium on “Advances in Predictive and Investigative Toxicology” on November 4, 2010, at Genentech. Our guest speakers from U.S. EPA, academics, and pharm/biotech industry will share the latest information in the field of investigative toxicology. Please view the attached meeting flyer containing the program, presentation abstracts and speaker biographical sketches. Pre-registration is highly recommended for security reason. It is a one-day meeting. Like always, we will have some fun networking with our colleagues and learn something new.

Meeting Presentations

Mail/Fax Registration Form

Meeting Flyer

Career Social Brunch

NorCal SOT is starting a “Career Building Social” program. This program is meant to extend our education outreach efforts, connecting students/postdocs and young scientists with veteran toxicologists.

Please join us for the first Career Building brunch on Saturday, October 30. We hope that the brunch will be filled with friendly, interesting people with which to network. The brunch will be held in an upstairs private room at Acqua Pazza in San Mateo. The food is reasonably priced and very good.

The agenda is loosely structured, providing an informal venue where students, young professionals and more seasoned toxicologists can get together to share experiences. We hope this format will facilitate relationship building that will foster more meaningful associations for both those seeking advice and those willing to share their experience.

More Information

Best regards,

Jeff Tepper (Program Coordinator) Vice President-Elect, NorCal SOT

2010 Spring Meeting

NorCal SOT will be hosting a Spring Meeting on Drug Development: From Small Molecules to Biologics on Thursday, May 6, 2010, at SRI International (333 Ravenswood Avenue, Menlo Park, CA 94025).

Registration is $25 for NorCal SOT members, $35 for nonmembers and FREE for students/postdocs. Students are encouraged to bring posters documenting their research and will receive $50 for doing so. Students may have their posters printed by contacting Steve Dizio. All attendees will have the opportunity to participate in a Lunch with an Expert program. The meeting is generously sponsored by BioReliance, Corp., California Department of Toxic Substances Control, ChanTest Corp., Charles River Laboratories, Comparative Biosciences, Covance, Genentech, ITR Laboratories, Inc., LAB Research, Inc., MPI Research Inc., Novartis, and SRI International.

View the meeting flyer containing the program, sponsors, presentation abstracts and speaker biographical sketches

Spring Meeting Presentations