Webinars and Downloads

Upcoming Webinars

Risk Assessment Specialty Section (RASS) with the International Society for Exposure Science (ISES) Webinar

Wednesday February 14, 2018 3:00 PM to 4:30 PM (EST)
(See below for Instructions on Webinar Access)

Exposure Assessment for Chemical and Non-chemical Exposures for Urban Epidemiology

Jane E. Clougherty, MSc ScD
Associate Professor
Drexel University Dornsife School of Public Health
Philadelphia, PA

Abstract

Stronger health effects of some chemical exposures—notably urban air pollution—have been observed in communities of lower socioeconomic position (SEP).  To better understand this differential susceptibility, there is a growing need to more accurately quantify social and physical environmental exposures, which may be spatially confounded in urban settings.
Separate epidemiologic and toxicologic evidence suggests that chronic stress—shown to influence immune, endocrine, and metabolic function—may exacerbate health effects of some pollutant exposures.  As a result, there is a need to accurately measure exposures to specific social stressors (e.g., poverty, exposure to violence), which may comprise SEP-related susceptibilities, and to develop methods for accurately testing their potential interactions with chemical exposures.

More clearly elucidating the specific factors underlying pollution susceptibility will improve our ability to identify and characterize at-risk populations, and to deliver targeted, cost-effective interventions to reduce health disparities.  In this presentation, Dr. Clougherty will describe new methods for: (1) quantifying chronic stress across large urban communities, and (2) accounting for potential confounding and effect modification by non-chemical stressors in environmental epidemiology.

Webinar Access Instructions

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Past Webinars

Webinar January 10, 2018: Assessing the Health Impact of Diverse Mixtures in the Environment

Webinar December 13, 2017: A Liver-centric Multiscale Modeling Framework for Xenobiotics

Webinar November 8, 2017: Systematic Review: Concept and Tool Development with Application to Assessment Processes of the National Toxicology Program (NTP) and the Integrated Risk Information System (IRIS)

Systematic Review Methods to Support Transparency and Consistency in Environmental Health Decision Making

Webinar October 11, 2017: A Source to Outcome Approach for Inhalation Risk Assessment

Webinar September 13, 2017: Mixing Hazardous Agents in a Mouse Model: Noise with Lead and Cadmium

Complex Mixtures of Anti-Androgens at Concentrations below Individual Chemical Effect Levels Produce Reproductive Tract Malformations in the Male Rat

Webinar May 10, 2017: Putting Exposure Back in Risk Assessment (Or: The Dose Makes the Poison)

Webinar April 12, 2017: Crowdsourcing Scientific Perspectives with SciPinion™: Hexavalent Chromium as a Case Study

Webinar February 8, 2017: How Can Mechanistic Data from Systems Approaches Improve our Understanding of Carcinogenic Risk for Mixtures?

Webinar January 11, 2017: German Environmental Survey and Environmental Specimen Bank and the Use of Human Biomonitoring Data for Risk Assessment

Webinar December 14, 2016: Aggregate Exposure Pathway (AEP): An Organizational Approach for Advancing Exposure Science Research and Applications

Webinar November 9, 2016: Improving Causal Inference in Cumulative Risk Assessment Using Directed Acyclic Graphs

Webinar October 12, 2016: Overview of TSCA Reform and Introduction to Key Provisions in the New
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Webinar May 11, 2016: Unconventional Gas and Oil Drilling Is Associated with Increased Hospital Utilization Rates

Webinar April 13, 2016: Studying Biology to Understand Risk: Dosimetry Models and Quantitative Adverse Outcome Pathways

Webinar February 10, 2016: Characterization of Murine Hepatocarcinogenesis Induced by the Nitrification Inhibitor Nitrapyrin: Mode of Action, Human Relevance Framework and Risk Assessment Implications

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Webinar December 9, 2015: Highly fluorinated chemicals: A Legal and Technical Challenge

Webinar November 18, 2015: Framework for Human Health Risk Assessment of Noncancer Effects Resulting from Short-Duration and Intermittent Exposures to Chemicals

Webinar October 14, 2015: The Integration of LNT and Hormesis for Cancer Risk Assessment Optimizes Public Health Protection

Webinar September 9, 2015: Mechanisms of Action for Arsenic in Cardiovascular Toxicity and Implications for Risk Assessment

Webinar June 10, 2015: Quantitative Evidence Integration to Facilitate the Use of Tox21 Data for Rapid Risk Screening

Webinar April 8, 2015: Adverse Outcome Pathways

Webinar February 11, 2015: CHAMACOS: Lessons from the Fields

Webinar January 14, 2015: Systematic Reviews, Risk of Bias and Evidence Evaluation for Characterization of Environmental Chemicals

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Webinar December 10, 2014: Improving Reproducibility in Toxicology

Webinar November 12, 2014: Introduction to Decision Analysis and Value of Information Analysis for Toxicology and Environmental Science

Webinar October 8, 2014: Every Breath You Take: Exposure Science and the Virtual Respiratory System

Webinar September 10, 2014: Toxicology for Breast Cancer Prevention

Webinar June 11, 2014: Environmental Decisions in the Face of Uncertainty

Webinar May 14, 2014: Cancer Clusters in the USA: What Do the Last Twenty Years of State and Federal Investigations Tell Us?

Webinar January 8, 2014: Environment-wide Association Studies (EWAS) to Connect Multiple Personal Exposures to Health

Webinar December 11, 2013: Providing the Missing Link: the Exposure Ontology (ExO) , High Throughput Human Exposure Forecasts for Environmental Chemical Risk

Webinar November 13, 2013: Approaches to Dose-response Analysis for Compounds with Endogenous Production: Two Case Studies Critical Issues for Formaldehyde Cancer Risk Assessment (Swenberg Presentation and Starr Presentation ) and Derivation of Methanol RfD and RfC—Accounting for Background Blood Levels

Webinar September 11, 2013: International Experience in Addressing Combined Exposures: Increasing the Efficiency of Assessment

Webinar May 8, 2013: Cumulative Risk Assessment: Approaches and Case Study

Webinar May 8, 2013: Evidence for the Existence of Nonmonotonic Dose-Response: Does It or Doesn’t It?

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Webinar April 10, 2013: Interface of Health Effects Caused by the CardioMetabolic Syndrome and Exposures to Air Pollutant Mixtures

Webinar February 13, 2013: Roundtable Panel Discussion: Should Journals Require the Release of Supporting Data As a Condition for Publication?

Webinar January 9, 2013: Mode of Action Research, Multispecies Pharmokinetic Modeling, and Risk Assessment for the Carcinogenesis of Hexavalent Chromium in the Small Intestine

Webinar December 12, 2012: Deming and Statistical Strategies to Make Observational Studies More Reliable

Webinar October 10, 2012: Alternative Methods for the Evaluation of Bioavailability of Arsenic in Mining Soils

Webinar September 12, 2012: A More Efficient and Effective Testing and Assessment Paradigm for Chemical Risk Management

Webinar June 13, 2012: Identification and Characterization of Adverse Effects in 21st Century Toxicology and Risk Assessment

Webinar April 25, 2012: Introduction to the New WHO/IPCS Guidelines for Immunotoxicity Risk Assessment for Chemicals

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Webinar February 8, 2012: Challenges in the Application Of Quantitative Approaches in Risk Assessment: A Case Study with Di-(2-Ethylhexyl)Phthalate

Webinar January 11, 2012: Comprehensive Environmental Assessment of Nanomaterials:
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Webinar December 14, 2011: Studies with Diesel Exhaust Particulate: Implications for the Potential Human Health Hazards of Nanoparticles

Webinar November 9, 2011: Risk from Multiple Chemicals in Polluted Communities

Webinar October 12, 2011: Estimating the Economic Value of Improved Information for Health Risk Assessment

Webinar June 8, 2011: Linear Low-Dose Extrapolation for Noncancer Health Effects Is the Exception, Not the Rule

Webinar May 11, 2011: The Maximum Cumulative Ratio (MCR): A Tool That Uses Both Exposure and Toxicity Data to Determine When Cumulative Assessments Are Most Necessary

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Webinar January 12, 2011: NexGen Risk Assessment Framework

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Teleconference November 10, 2010: The Use of PBPK Modeling to Reduce Uncertainty in Risk Assessment: Example of Manganese

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Teleconference June 30, 2010: Developments and Good Practice in Mode of Action/Human Relevance Anaylsis

Teleconference June 9, 2010: Analyzing Genomic Dose-Response Information to Inform Key Events in a Mode of Action for Carcinogenicity: An Example with Arsenic

Teleconference May 12, 2010: Opportunities for Progress in the Applications of Mechanistic Information in Risk Assessment

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Teleconference November 12, 2008: Pb NAAQS Human Health Risk Assessment—Overview of Design and Implementation

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Updated Principles for Risk Analysis—Nancy Beck

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Model Averaging: Beyond Model Uncertainty in Risk Analysis—Matthew W. Wheeler

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The Application of Genomic Dose-Response Data in Risk Assessment—Harvey Clewell and Rusty Thomas CIIT Centers for Health Research

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