Program Overview

Nearly 60 Scientific Sessions will be presented as part of the Virtual 2021 SOT Annual Meeting, alongside 14 Continuing Education courses. The titles of the accepted sessions and courses are listed on this web page. More details on these sessions, as well as the official schedule, will be available in the coming months.


IAT Innovations in Applied Toxicology   ITS Innovations in Toxicological Sciences

In focus in the background of the image is a man standing behind a lecture podium on a stage. A large projection screen is behind the man and is partially displaying him standing at the podium. Behind the screen are curtains that alternate between aqua and royal blue. In the foreground of the photo, you can see the backs of people’s heads. These people are seated in rows all facing the stage and the man at the podium.

Opening Plenary Session: Blending Art and Science to Master Science Communication

Monday, March 15, 10:00 AM to 11:00 AM

Speaker: Laura Lindenfeld, Alan Alda Center for Communicating Science, Stony Brook University, Stony Brook, NY.

In this keynote, Dr. Lindenfeld will introduce participants to the Alda Center’s unique approach to science communication. Building on the foundations of improvisational theater, which cultivates a stronger ability to relate and connect, the Alda Center leverages scientific research on science communication to empower scientists to connect with diverse audiences in clear and vivid ways.


SOT will present 14 Continuing Education courses during the 2021 Annual Meeting and ToxExpo. Visit the “Continuing Education” web page for the full descriptions, presenters, and other details.

  • SR01: Chemical Probes: New Tools to Identify Molecular Targets
  • SR02: Insider Secrets for Design and Analysis of Defined Mixture Experiments
  • AM03: Advances in Single Cell Genomic Analyses for Toxicological Testing
  • AM04: Guidelines for Developing and Implementing Organ-on-a-Chip/Microphysiological Systems for Toxicity Evaluation of Drug Candidates in Drug Development
  • AM05: Less Is More: Sustainable Product Development Requires More Toxicological Considerations
  • AM06: Rapid Chemical Assessment Using Open Computational Methods
  • AM07: Risk Assessment, DART, and Endocrine Disruption: A World View
  • AM08: Timing Is Everything: Role of Aging in Immune Responses and Toxicological Implications
  • PM09: Applications of In Vitro and In Silico New Approach Methodologies for Predictive and Mechanistic Thyroid Toxicity Testing
  • PM10: Concepts and Approaches for Current and Future Metals Toxicological Research
  • PM11: Development, Toxicology, and Pathology of the Female Reproductive Tract: Interpretation of Findings from the Pathologist and Regulatory Perspectives
  • PM12: Establishing Confidence in Organ-on-a-Chip Systems for Toxicity Testing: Lung-on-a-Chip as an Example
  • PM13: Navigating New Modalities: A Preclinical Roadmap for Developing a Novel Oligonucleotide Safety Strategy
  • PM14: Understanding Tox21/ToxCast High-Throughput Screening Data and Applications to Modeling


  • Across the Life Span: Emerging Mechanisms of Prenatal and Transgenerational Toxicity
  • Application of Computational Genomic Approaches to Address Toxicity Mechanisms and Prediction
  • Applications of Novel High-Throughput Approaches for Mechanism-Based Chemical Safety Assessment
  • Botanical Mixtures: Predictive Approaches to Evaluating Pregnancy, and Reproductive and Developmental Health
  • Challenges and New Approaches in Characterizing Toxicity within the Military
  • Challenges and Opportunities in Applying Quantitative and Translational Systems Toxicology Models to Drug Safety Testing ITS
  • Closing the Data Gap: Assessing Population Variability Using Next-Generation Tools in Toxicology
  • Controlling the Message: Safely Navigating the Development of Novel Oligonucleotide Therapeutics
  • Developmental Toxicity Hazard Assessment without Animals: Pathways and Prospects IAT
  • Environmental Influences on Placental Origins of Development
  • Evolving Technologies for Determination of Biotherapeutic Specificity
  • From Conception to Cane: Unique Life-Stage Considerations for Reproductive Toxicity
  • From Inhaled Particles to Neurodegeneration and Toxicity: Evidence from Studies in Volunteers, Experimental Animals, and Cell-Based Systems
  • Hereditary Disorders of Manganese Metabolism: Mechanisms, Clinical Presentation, and Neurotoxicity ITS
  • Identifying and Communicating Adverse Neurological Outcomes from Parental Cannabis Use
  • Impaired Brain Barrier Systems: Relationship to Chemical-Induced Neurotoxicities
  • Industrial Applications of Artificial Intelligence in Toxicology
  • It Is Not Just Air: Exposure to Indoor Air Pollution, Diagnostic Tools, and Evaluation of Health Effects
  • Mind the Gap: Finding Practical Ways to Fast-Track the Future of Animal-Free Toxicology Testing
  • Nonclinical Safety Toxicology Strategies for the Development of Novel Ocular Biotherapeutics
  • Novel Emerging Treatments for Acetaminophen Toxicity
  • Opportunities and Challenges in Utilization of Toxicokinetic Data in Dose-Level Selection for Repeated-Dose Toxicity Studies
  • Opportunities for Human-Induced Pluripotent Stem Cell–Derived Neurons in In Vitro Neurotoxicity Safety Testing
  • Pairing Adverse Outcome Pathway Discovery with Advances in Gene Editing to Solve Toxicity Mechanisms
  • SETAC-SOT Session: Environmental Risk Assessment of PFAS
  • Testing the Waters: How the Zebrafish, Xenopus, and Medaka Models Are Advancing Our Understanding of Reproductive and Developmental Toxicity
  • The Power of Integrating Computational Toxicology with Multiparametric In Vitro Assay Systems


  • A Future Framework for Application of In Vitro Metabolism and QIVIVE Models to Inform Risk Assessment
  • Applicability Domains and Future of Nonanimal Tests for Skin Sensitization
  • Are Aircraft Cabin Fume Releases a Cause for Toxicological Concern?
  • Bile Acids Profiling as Biomarkers for Hepatobiliary Toxicity and Disease
  • Cannabidiol 2021: Science, Safety, and Societal Issues IAT
  • Chemical-Induced Mouse Lung Tumors: Mode of Action, Relevance, and Risk Assessment
  • Establishing Quality, Safety, and Regulatory Principles for Probiotics: More Than Just a Gut Check
  • Improving Our Understanding of Toxicant Metabolism and Cytochrome P450s Using Novel Knockout Models and High-Throughput Methods
  • Molecular-Based Points of Departure as the New Basis for Chemical Risk Assessment: Are We Ready?
  • Navigating Your Health and Wellness through Graduate School and Early Careers
  • New Approach Methodologies for Exposure: Advancing Chemical Risk Assessment
  • New Approach Methods for Cancer Risk Assessment
  • New Approaches for the Identification and Evaluation of Chemical Respiratory Sensitizers
  • Paving the Way for Greater Data Sharing to Advance Biomarker and Drug Development: Industry, Academia, and Regulatory Insights
  • Precision-Cut Lung Slices: A Versatile Tool for Pulmonary Toxicology
  • Regulatory Learnings from the EU Flagship Nonanimal Toxicology Project, EU-ToxRisk
  • Revising Biology: Alternative Splicing in Toxicology
  • Standardization of In Vitro Inhalation Exposure for Regulatory Acceptance
  • Tackling the Potential Human Health Impacts of Microplastics and Nanoplastics: Challenges for Toxicologists in the Assessment of Real-World Complex Mixtures
  • The Community Exposome: Effects of Environmental Contamination on Health Disparities and Marginalized Populations through the Lens of a Toxicologist
  • The Methodological Road toward Single Cell High-Throughput Transcriptomics (scHTTr) IAT
  • The Scientific Challenges in Regulating Organohalogen Flame Retardants (OFRs) as a Class in Consumer Products
  • Thresholds of Toxicological Concern: Reassessing the Basis and Expanding the Horizon
  • Using Human Genetics to Aid in Safety Assessment of Therapeutics ITS
  • The Need for Protocol Harmonization in the Advancement of Zebrafish as a Model for Toxicological Screening: Global Perspectives and Recent Advancements


  • The Future of Uncertainty Factors with In Vitro Studies Using Human Cells


  • Safety Assessment of Devices Used in Assisted Reproduction Technology: Mouse Embryo Assay
  • Strategies to Increase Global Awareness of Toxicology: Focus on Developing Countries
  • Toxicology for Chemists: Preparing Chemists to Design Safer Products through Smarter Molecular Design
  • Turning Over a New Leaf: An Update on the Clinical Toxicology of Synthetic Cannabinoids
  • Understanding the Spread and Toxicological, Environmental, and Public Health Impact of the COVID-19 Pandemic on the African Continent


  • Innovation in Toxicology Training during Summer Undergraduate Internships


  • Undergraduate Diversity Program
    Organized by the SOT Committee on Diversity Initiatives, this program is designed for sophomores and juniors and students who are from racial/ethnic groups underrepresented in the sciences, are first-generation college students, or are attending institutions receiving low amounts of federal funding for biomedical research.
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  • Undergraduate Education Program
    Undergraduate students are invited to participate in the complimentary Undergraduate Education Program, but registration is required.
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