Schedule and Publications

Sunday, March 19, 7:00 AM to 7:45 AM

Separate Registration and Fee

• An Introduction to Clinical and Medical Toxicology

Sunday, March 19, 7:15 AM to 7:45 AM

By invitation only

Sunday, March 19, 8:00 AM to 5:00 PM

Free Reservation Required

Sunday, March 19, 8:15 AM to 12:00 Noon

Separate Registration and Fee

• AM02: A Training on the OECD Guidance for Characterizing, Validating, and Reporting Physiologically Based Kinetic Models
• AM03: Advanced Discovery Toxicology: Integrating Toxicology with Other Functions on the Team
• AM04: Beyond the Powerhouse: Investigating Mechanisms of Mitotoxicity
• AM05: Non-traditional In Vivo Animal Models in Developmental, Reproductive, and Juvenile Toxicology
• AM06: Tools Supporting Open Chemical Evaluations
• AM07: Unique Applications of Systematic Review Methods: Assessment of Ecotoxicity, Environmental Fate, Exposure, Mechanisms, and Comparison of Test Methods

Sunday, March 19, 1:15 PM to 5:00 PM

Separate Registration and Fee

• PM08: Checking In on Adverse Outcome Pathways: Evolving Development, Evaluation, and Application
• PM09: Immunosafety: Current Considerations and Applications in the Landscape of Immunomodulatory Therapies
• PM10: PM10: In Vitro to In Vivo Extrapolation Strategy and Guidance across Organ System Toxicities
• PM11: Inhalation Drug Development: Back to Basics
• PM12: Making the Most of Your Data: How to Build Machine-Learning Models for Toxicology
• PM13: Put Your Science Where Your Mouth Is: Practice Makes Progress in Effective Science Communication

Sunday, March 19, 5:15 PM to 6:30 PM

Sunday, March 19, 6:30 PM to 7:30 PM

Sunday, March 19, 7:00 PM to 8:00 PM

By invitation only

Sunday, March 19, 7:30 PM to 9:00 PM

Free Reservation Required

Monday, March 20, 6:15 AM to 7:45 AM

Add-On Event

Monday, March 20, 8:00 AM to 9:00 AM

Namandjé N. Bumpus

US FDA, College Park, MD.

Monday, March 20, 8:00 AM to 5:00 PM

By Invitation Only

Monday, March 20, 9:00 AM to 4:30 PM

Monday, March 20, 9:15 AM to 12:00 Noon

Symposium Sessions

• AI Buzz or Bliss: Case Studies for Successful Applications of Artificial Intelligence in Predictive Toxicology
• House on Fire: Chemistry and Toxicology of Structural Fire Smoke at the Wildland Urban Interface
• Mechanistic Insights on Gene x Environment Interactions in Autism
• Microplastics: Factors to Consider When Assessing Potential Environmental and Human Health Risks

Workshops Sessions

• Biocompatibility Assessment of Absorbable/Degradable Materials Employed in Medical Devices: Challenges, Pitfalls, and Emerging Testing Methods
• Drug-Induced Liver Injury: Challenges and Opportunities to Predict and Measure the Hepatotoxic Potential of Therapeutic Agents in Early and Late Phases of Drug Development and after Marketing
• Understanding the Concept of Similarity and Its Applications to Toxicological Research and Risk Assessment

Monday, March 20, 9:30 AM to 3:00 PM (hours may change)

Monday, March 20, 9:30 AM to 10:30 AM

Free Reservation Required

Monday, March 20, 12:00 Noon to 1:30 PM

Add-On Event

Monday, March 20, 12:10 PM to 1:30 PM

Roundtable Sessions

• A Transformative Vision for an ’Omics-Based Regulatory Chemical Testing Paradigm
• Evaluating and Rethinking the Use of Dogs in Agrochemical Evaluation and Registration
• OK, Google, “How Do I Science?” Roles and Responsibilities of Developers and Users in Computational Toxicology

Informational Session

• Toxicology, Translational, and Regulatory Considerations of Antisense Oligonucleotides and Other RNA-Centric Modalities

Monday, March 20, 1:45 PM to 4:30 PM

Symposium Sessions

• Humanized Mouse Models for Preclinical Evaluation of CAR T Cells
• New Approach Methodologies to Evaluate Botanical Safety
• Placenta as a Target of Environmental Exposures: From Bench to Society
• Playing with Fire: Human Exposure, Health Risks, and Safer Design of Flame Retardants
• Using a Toxic Aging Coin to Investigate the Intersection of Toxicology and Aging: Heads for Age Differences, Tails for Gerontogens

Workshop Session

• Establishing Scientific Confidence in New Approach Methods: A Modern Framework

Monday, March 20, 3:00 PM to 4:30 PM

Monday, March 20, 4:30 PM to 5:30 PM

Monday, 4:45 PM to 6:05 PM

SOT Debater: Robert O. Wright

Icahn School of Medicine at Mount Sinai, New York, NY.

EUROTOX Debater: Robert Barouki

Université Paris Descartes, Paris, France.

Tuesday, March 21, 8:00 AM to 10:45 AM

Chris Corton

US EPA, Research Triangle Park, NC.

Keiko Taguchi

Tohoku University School of Medicine, Sendai, Japan.

John P. Wise Sr.

University of Louisville, Louisville, KY.

Naoko Hattori

National Cancer Center Research Institute, Tokyo, Japan.

Tuesday, March 21, 8:00 AM to 10:45 AM

Symposium Sessions

• Breaking Down Barriers: Blood-Brain Barrier Model Development and Applications in Drug Safety
• Challenges in the Development of In Vitro-In Vivo Extrapolation Models for Next-Generation Risk Assessment

Workshop Sessions

• A Current Perspective on Environmental Chemicals and Their Role in Initiating and Exacerbating Cardiovascular Disease
• Continuing toward Best Practices in Organizing, Assessing, and Applying Mechanistic Data in Hazard Characterization and Risk Assessment
• Developing Human-Relevant New Approach Methodologies to Measure Key Events in Pulmonary Adverse Outcomes: Focus on Chronic Endpoints
• How to Be an Active Ally and Upstander for Promoting an Inclusive Environment in Toxicology

Tuesday, March 21, 9:00 AM to 4:30 PM

Tuesday, March 21, 9:30 AM to 3:00 PM (hours may change)

Tuesday, March 21, 11:00 AM to 12:30 PM

Workshop Session

• Establishing Confidence in New Approach Methods for Human Health Risk Assessment: Recent Examples of Context of Use

Tuesday, March 21, 12:00 Noon to 1:00 PM

Add-On Event

Tuesday, March 21, 12:30 PM to 1:30 PM

Tuesday, March 21, 1:00 PM to 2:00 PM

William Joel Meggs

East Carolina University Brody School of Medicine, Greenville, NC.

Andrew A. Monte

University of Colorado Anschutz Medical Campus, Aurora, CO.

Tuesday, March 21, 1:00 PM to 3:45 PM

Rick Woychik

NIEHS/NTP, Research Triangle Park, NC.

Christopher Frey

US EPA/ORD, Research Triangle Park, NC.

Steven Musser

US FDA/CFSAN, College Park, MD.

Tuesday, March 21, 1:00 PM to 2:30 PM

Jeffrey M. Peters

Pennsylvania State University, University Park, PA.

Kristine Willett

University of Mississippi, University, MS.

Matthew J. Campen

University of New Mexico, Albuquerque, NM.

Tuesday, March 21, 1:00 PM to 2:30 PM

Symposium Session

• Achieving Successful Reproducibility for Next-Generation Toxicological Methods

Workshop Sessions

• Challenges and Future Directions in NAM Applications to Mixtures Risk Assessment
• Crucial Role of Physiologically Based Pharmacokinetic (PBPK) Modeling in Human Health Risk Assessment in Different Sectors
• Placental Biology, Toxicology, and In Vitro Modeling for Predictive Developmental Toxicology

Tuesday, March 21, 1:30 PM to 2:50 PM

Free Reservation Required

Tuesday, March 21, 3:00 PM to 4:30 PM

Symposium Session

• It’s Getting Hot: Extreme Heat Events and Disparate Health Impacts, Perceptions, and Vulnerability

Workshop Sessions

• Down the Rabbit Hole: Exploring the Rabbit as a Nonrodent Species in the Wake of Primate and Dog Shortages
• Computational Visualization Tools for Communicating Large, Complex Data

Tuesday, March 21, 4:45 PM to 6:15 PM

Tuesday, March 21, 7:30 PM to 9:00 PM

Wednesday, March 22, 8:00 AM to 10:45 AM

Symposium Sessions

• Expanding Our Knowledge of Neurological Disease Etiologies: Current Research on the Neural Exposome
• Human Cells as Nonanimal Alternative Approaches for Immunotoxicity Testing
• Metals Matter: The Potential Effects of Metal-Mediated Cell Death in the Pathogenesis of Cardiopulmonary Diseases
• The Future of Fire Safety: Exploring the Intersection of Wildfires and Human Health

Workshop Sessions

• Cancers, Chemicals, and the Microbiome
• Moving Stem Cell–Derived New Approach Methods toward Regulatory Acceptance
• Peer Reviewing for Scholarly Journals: Best Practices, Tips, and Case Studies
• Shedding Light on Population Variability and Susceptibility: New Approach Methods to Inform Risk Assessment
• Targeted Protein Degradation Therapeutics: Opportunities and Challenges

Wednesday, March 22, 9:00 AM to 4:30 PM

Wednesday, March 22, 9:30 AM to 3:00 PM (hours may change)

Wednesday, March 22, 11:00 AM to 12:00 Noon

Helena Kandarova

Slovenská Akadémia Vied, Bratislava, Slovakia.

Wednesday, March 22, 11:00 AM to 12:20 PM

Roundtable Session

• 21st-Century Agrochemical Evaluation: Discussing a New Vision

Informational Session

• Evidence-Based Methods in Toxicology: Progress in the Past Decade and Collaborative Projections for the Future

Education-Career Development Session

• A Day in the Life of an Industry Toxicologist

Wednesday, March 22, 12:30 PM to 1:30 PM

Emma Rawlins

University of Cambridge Gurdon Institute, Cambridge, United Kingdom.

Wednesday, March 22, 1:30 PM to 4:15 PM

Symposium Sessions

• Epitranscriptomic Mechanism of Metal Toxicity and Carcinogenesis
• Opening Our Eyes: Ocular Gene Therapies from Theory to Practice
• Tackling the Challenge of Assessing Human-Relevant Thyroid Disruption
• Toxicology 2.0: Moving from Reductionist to Holistic Paradigms

Workshop Sessions

• Grappling with the Grim Reaper: Epigenetics of Aging
• New Approach Methodologies in the Pharmaceutical Sciences: Novel Strategies Challenging the Traditional Testing Paradigm to Increase Regulatory Confidence
• Safety Assessment Approaches for Stem Cell Therapy

Wednesday, March 22, 2:00 PM to 3:00 PM

Free Reservation Required

Thursday, March 23, 8:30 AM to 11:15 AM

Symposium Sessions

• High-Content Imaging: Cell Painting Basics and Emerging Applications to Toxicological Research
• Refining Inhalation Risk Assessments by Integrating New Approach Methodologies
• What’s All the Buzz about Tungsten?

Workshop Sessions

• A Roadmap to Modernized Agrochemical Carcinogenicity Assessment
• Cannabis Contaminants: Current Status of Regulations and Implications to Public Health
• Emerging Environmental Contaminants and Issues of Concern: Developing Toxicologic Strategies to Identify and Address Tomorrow’s Public Health Issues